• Journal of Periodontal and Implant Science
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• v.37 no.sup2
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• pp.311-323
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• 2007

Receptor activation of nuclear factor ${\kappa}$ B ligand (RANKL)은 파골세포의 분화와 기능에 중요한 역할을 하는 단백질로 이들 물질의 조절에는 p38 MAP kinase가 관여한다. 그러나 치주인대 섬유모세포에서 RANKL 발현 시 p38 MAP kinase의 역할은 잘 알려져 있지 않다. 이에 이번 연구는 마우스 치주인대 섬유모세포의 $IL-1{\beta}-induced$ RANKL 발현과정에서 p38의 역할을 규명하고자 하여 다음과 같은 결과를 얻었다. 마우스 치주인대 섬유모세포에 $IL-1{\beta}$ (1ng/ml)의 자극은 수용성 RANKL의 합성을 증가시켰다. 수용성 RANKL의 합성은 p38 MAP kinase 억제제인 SB203580에 의해 농도 의존적으로 억제되었으나 다른 MAP kinase 억제제인 SP600125, JNK 억제제와 PD98059, ERK 억제제에 의해서는 수용성 RANKL의 합성이 조절되지 않았다. NF-kB 억제제에 의해서도 수용성 RANKL의 합성이 억제되지 않았다. RANKL 유전자의 발현은 $IL-1{\beta}$로 자극 시에는 대조군에 비해 약 5배의 발현 증가를 보였으나 SB203580으로 전처치 시 $IL-1{\beta}$ (1ng/ml)로 자극시보다 약 1.5배의 감소를 보였다. 그러나 SP600125, PD98059, 및 NF-kB 억제제로 전처치한 경우에는 $IL-1{\beta}$로 자극한 경우와 비슷한 수준을 보였다. $IL-1{\beta}$로 자극 시 RANKL 유전자의 반감기가 90분 이었으나 SB203580로 전처치 후 $IL-1{\beta}$로 자극 시 RANKL 유전자의 반감기는 60분으로 감소하였다. Cycloheximide 전처리 시 SB203580에 의한 RANKL 유전자 발현 억제가 관찰되지 않았다. 단백질 분석결과 p38 MAP kinase의 인산화 활성은 30분까지 증가하였으나 그 이후 감소하여 2시간째에는 그 발현이 미약하였다. SB203580로 전처치 후 $IL-1{\beta}$로 자극 시 p38 MAP kinase의 인산화 활성이 감소하였다. 이상의 결과는 p38 MAP kinase가 RANKL 유전자 조절에 중요한 역할을 담당하고 있음을 시사한다.

• Honam Mathematical Journal
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• v.38 no.2
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• pp.305-316
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• 2016

In this paper we study general rotational surfaces in the 4-dimensional Euclidean space $\mathbb{E}^4$ and give a characterization of flat general rotational surface with pointwise 1-type Gauss map. Also, we show that a flat general rotational surface with pointwise 1-type Gauss map is a Lie group if and only if it is a Clifford torus.

• Journal of the Korean Mathematical Society
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• v.35 no.2
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• pp.315-330
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• 1998

Chen and Piccinni [7] have classified all compact surfaces in a Euclidean space $R^{2＋p}$ with 1-type generalized Gauss map. Being motivated by this result, the purpose of this paper is to consider the Lorentz version of the classification theorem and to obtain a complete classification of space-like surfaces in indefinite Euclidean space $R_{p}$ $^{2＋p}$ with 1-type generalized Gauss map.p.

• Knowledge Management Research
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• v.13 no.1
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• pp.1-12
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• 2012

A knowledge map is a network-typed diagram visualizing all kinds of knowledge that influences each other to solve a problem. A knowledge map determines the structure of knowledge categorizing and archiving by defining the relationship of referential navigation among knowledge. Since tremendous and increasing number of knowledge needs to be included in a knowledge map, a knowledge map must be organized automatically by considering the contents and relationships of knowledge. This paper suggests the concept and prototype of a semi-automated knowledge map which automatically maps new piece of knowledge onto a manually provided draft map. The prototype knowledge map is based on the recursive programming to make a knowledge map automatically determine the location of the newly-entered knowledge by considering the referential relationship between knowledge. The proposed knowledge enables the knowledge network to expand autonomously by automatically including and storing knowledge. Also, it can improve the accuracy and applicability of knowledge for problem-solving, because the relationship of referential navigation among knowledge can be efficiently and effectively expressed.

• Korean Journal of Remote Sensing
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• v.8 no.1
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• pp.45-58
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• 1992

The study is aimed at extraction of the groundwater potential area using the Geographic Information System. The study was to develop techniques of the thematic mapping such as slope map, geologic map, soil map and suitability mapping for grotential area. There thematic maps were combined and weightages were given to produce suitability map for groundwater potential area. The results of this study are as follows. 1) The 78% of cased wells have releation to lineament coincided with the appraisement point of the suitability map. 2) The 9 sites of 18 test sites produced over than 200 m$^3$/day. The with the highest appraisement point of the suitability map. 3) Suitability map is effective to extract groundwater potential area which can not be extracted from the remotely sensed data. The developed suitability mapping techniques are expected to do as an important tool for exploration and development of the newable and unnewable resources such as groundwater, petroleum etc.

• Journal of the Korean Mathematical Society
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• v.41 no.6
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• pp.1007-1021
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• 2004

In this paper, we study rotation surfaces in the Minkowski 3-dimensional space with pointwise 1-type Gauss map and obtain by the use of the concept of pointwise finite type Gauss map, a characterization theorem concerning rotation surfaces and constancy of the mean curvature of certain open subsets on these surfaces.

• Journal of Korean Society for Geospatial Information Science
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• v.13 no.1 s.31
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• pp.27-35
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• 2005

It is impossible to call in the cost of map-production from the supply cost because the map produced in NGI is the public property. The aims of this research are to calculate a map manufacture cost and to assess the reasonable map prices with considering public property of map. For these aims, We have calculated the cost according to the scale and the form of paper and digital map, have determined the map supply cost, and have analyzed the situation of map supply and the map circulation market. We propose two alternatives. Firstly, supply price of map is reached the goal price after 6-years(raising ratio 30%) and Secondly, supply price of map is reached the goal price after 3-years(raising ratio 50%) because map supply price raising ratio is very much if research results are reflected after 1-year.

• Journal of Bio-Environment Control
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• v.32 no.4
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• pp.267-277
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• 2023

This study is in order to the effect of 1-methlycyclopropene (1-MCP) treatment and film package as modified atmosphere packaging (MAP) on the changes in fruit quality factors of 'Daehong' peaches during cold storage. The concentrations of 1-MCP were treated at 1µL·L^-1 and 2µL·L^-1, and peaches in film package were stored for 28 days in cold storage at 5±1℃ and 85±5% RH. The fruits stored carton box were used as a control of MAP, and 1-MCP free fruits were used as the control of both packages. Rate of fresh weight loss during storage was not significantly different between groups with and without 1-MCP treatment, but was higher in the box package than in the MAP. The control group had a higher incidence of both gases with the 1-MCP treatment group showing statistically significantly low. Carbon dioxide in the package was lowered by about 12% compared to the non-treated group, and the ethylene concentration was maintained at 1µL·L^-1, showing a significance low compared to other treated groups. As the storage period elapsed, the firmness of 1-MCP and MAP treated fruits remained significant at 5-9% compared to the control group. Regardless of the packaging method Hunter a^* values of exocarp and mesocarp were significantly higher in fruit treated with 1-MCP 1µL·L^-1 treatment than in the control group, and anthocyanin was significantly higher in the fruit during the storage period, especially high in MAP. In summary, fruits of MAP group with 1-MCP 1µL·L^-1 had rate of lower respiration and ethylene production, and little changes in firmness, Hunter a^* values of exo-carp and meso-carp, and anthocyanin, which is considered the most suitable method for preserving postharvest quality of the peach cultivar during the storage.

• Journal of the Korean Mathematical Society
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• v.55 no.4
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• pp.923-938
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• 2018

In this paper, we handle the Gauss map of a tubular surface which is constructed according to the parallel transport frame of its spine curve. We show that there is no tubular surface having harmonic Gauss map. Moreover, we give a complete classification of this kind of tubular surface having pointwise 1-type Gauss map in Euclidean 4-space ${\mathbb{E}}^4$.

• Journal of Environmental Impact Assessment
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• v.7 no.2
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• pp.27-35
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• 1998

In Korea, the initial installation of GIS requires lots of cost, time, and human efforts. If the accuracy of GIS data does not meet the certain standard for use, the system may not work as expected. So, it needs to be investigated for the accuracy of raw data. However, there is little study for the accuracy of raw data in Korea. Therefore, the purpose of this study is to review the data accuracy of raw data - geologic map, 1:5,000 and 1:25,000 scale topographic map, forest stand map, degree of green naturality(DGN) map, and detailed survey data of DGN map-, which are to be used in Environmental Information System(EIS) in Korea. After this study, some errors in data were surveyed and following conclusions were derived. (1) There is no map data, e. g, wildlife habitat map. (2) Some data are misinterpreted depending on the location in the geologic map. (3) Some data are not updated properly after change of topography in the topographic map or the elevation and location is different depending on the scale.. (4) Some data are not edited properly in the forest stand map, e. g. two attributes in one polygon. (5) DGN classification system does not reflect the characteristic of Korean vegetation community. So, it needs to be refined and restructured.