• 한방재활의학과학회지
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• 제21권4호
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• pp.23-40
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• 2011

Objectives: This study was designed to examine the effects of extracts of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) on the lipid lowering, anti-oxidation and concentration of proinflammatory cytokines and was investigated on hyperlipidemic rats. Methods: Male rats weighing $182.39{\pm}4.71g$ were fed high fat diet for 8 weeks and 36 rats(above 400 g) were divided into 4 groups. Each of 9 rats was divided a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline(100 mg/kg, 1 time/1 day) for 4 weeks. And we fed each experimental group of rats basal diet and administered an extract of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) extracts(100 mg/kg, 200mg/kg, 300 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflmmatory cytokines, anti-oxidative activity and $TNF-{\alpha}$, Apo-B, Apo-E and leptin gene expression. Results: 1. Concentration of plasma free fatty(FFA) showed no significant difference in all the treatment groups. Concentration of plasma triglyceride(TG) showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 2. Concentration of plasma total cholesterol showed a significant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma low density lipoprotein(LDL)-cholesterol showed a Significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma high density lipoprotein(HDL)-cholesterol showed a significant increment in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group. 3. Concentration of liver total cholesterol showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. Concentration of liver TG showed a significant decrement in all Ojeoksangamibang groups than that of control group. 4. Concentration of plasma and liver thiobarbituric acid reactive substance(TBARS) showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. 5. The values of glutathione peroxidase(GSH-Px), superoxide dismutase(SOD) and catalase(CAT) activity showed a significant increment in all Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 6. The values of plasma aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activity showed no significant different in all treatment group. 7. Concentration of plasma $interleukin(IL)-1{beta}$ showed no significant difference in all the treatment groups. Concentration of plasma IL-6 showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. Concentration of plasma tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ a siginifant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. However the concentration of plasma IL-10 in the 300 mg/kg Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant increment than that of control group. 9. In the analysis of reverse transcription-polymerase chain reaction(RT-PCR), gene expression of $TNF-{\alpha}$, Apo-B and Apo-E in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a lower expression than that of control group. However the gene expression of leptin showed no difference in the treatment groups. 10. The ratio of $TNF-{\alpha}$, Apo-B, and Apo-E per ${\beta}-actin$ expression in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant decrement than that of control group. However The ratio of leptin expression per ${\beta}-actin$ expression showed no significant difference among all the treatment groups. Conclusions: According to above results, in lowering lipid effect, anti-oxidation and control of pro-inflammatory cytokines production, Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) gives effect.

• Natural Product Sciences
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• 제5권2호
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• pp.85-87
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• 1999

Two new sesquiterpenes, 3'-chloro-2'-hydroxy-3-epi-arguticinin (1) and argutenol (2) belonging to eudesmane and gorgonane classes respectively, have been isolated from Pluchea arguta. Their structures were elucidated with the help of sophisticated spectroscopic techniques including nOe difference and NOESY experiments.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2007년도 The 1st International Symposium on Advanced Magnetic Materials
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• pp.15.2-15.2
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• 2007

• Journal of applied mathematics & informatics
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• 제38권1_2호
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• pp.189-200
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• 2020

Let G be a simple connected graph with n vertices and m edges. Denote by d₁ ≥ d₂ ≥ ⋯ ≥ d_n > 0 and d(e₁) ≥ d(e₂) ≥ ⋯ ≥ d(e_m) sequences of vertex and edge degrees, respectively. If vertices v_i and v_j are adjacent, we write i ~ j. The general sum-connectivity index is defined as 𝒳_α(G) = ∑_i~j(d_i + d_j)^α, where α is an arbitrary real number. Firstly, we determine a relation between 𝒳_α(G) and 𝒳_α-1(G). Then we use it to obtain some new bounds for 𝒳_α(G).

• 대한수학회논문집
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• 제17권4호
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• pp.719-729
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• 2002

Consider the random n $\times$ m assignment problem with m $\geq$ $_{i,j}$ Let $u_{i,j}$ be iid uniform random variables on [0, 1] and exponential random variables with mean 1, respectively, and let $U_{n, m}$ and $T_{n, m}$ denote the optimal assignment costs corresponding to $u_{i, j}$ and $t_{i, j}$. In this paper we first give a comparison result about the discrepancy E $T_{n, m}$ -E $U_{n, m}$. Using this comparison result with a known lower bound for Var( $T_{n, m}$) we obtains a lower bound for Var( $U_{n, m}$). Finally, we study the way that E $U_{n, m}$ and E $T_{n, m}$ vary as m does. It turns out that only when m - n is large enough, the cost decreases significantly.tly.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 춘계학술대회 논문집 전력기술부문
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• pp.123-125
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• 2001

In general, the PSS/E program is used for analyzing KEPCO System in terms of stability and the EMTDC Program is needed to analyze the transient characteristics of power system. The FSS/E provides various control models such as exciter. governor and PSS models whereas there ale few control of models in EMTDC. In this paper. we developed an EMTDC model for IEEET3 exciter which has been applied in KEPCO system. The EMTDC model is developed by examining PSS/E control block and using User Define Model in addition to default.lib provided by EMTDC we verify the correctness of developed IEEET3 model with PSS/E and EMTDC simulation results for the same test system.

• 한국전자파학회:학술대회논문집
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• 한국전자파학회 2000년도 종합학술발표회 논문집 Vol.10 No.1
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• pp.297-301
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• 2000

ELF 전자파의 생물학적인 영향 평가를 위한 in vitro 세포 실험에서 노출장치의 설계는 코일내피 유도기전력(E)과 전류밀도(J) 해석과 함께 이루어져야 한다. 균일 자기장 속에서 세포를 배양할 경우애도 배양기내의 전도성 매질로 인해 균일한 E와 J가 분포하지 않는다. 따라서 균일한 ELF 자기장 노출장치로부터 발생되는 샘플 매질 내에서의 E나 J를 정확히 예측하는 것은 in vitro 세포실험의 성공여부를 가늠 할 정도로 매우 중요한 정보가 된다. 이에 본 논문에서는 in vitro 실험에 적합한 ELF in vitro 노출 장치를 설계하고 노출 장치에 대한 전자기학적 평가를 수행하였다. 코일 내에서 샘플 매질의 유무와 샘플 내에서도 세포가 놓여질 임의의 위치에 따라 E와 J를 예측하고 검증을 위한 측정과 시뮬레이션을 시도하였다. 노출장치는 헬름 홀쯔 코일로 제작되었고 자기장의 세기는 1-2OG 범위 내에서 가변이 가능하다. 또한 코일내의 자기장의 분포가 균일(uniform), 비균일(nonuniform)만 두 가지모드를 각각 제작하여 보았다.

• Natural Product Sciences
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• 제4권3호
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• pp.170-173
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• 1998

A new derivative of allo-inositol has been isolated from the aerial parts of Stocksia brahuica and named as brahol (1). The structure of 1 was elucidated with the help of extensive 2D-NMR spectroscopic techniques and identified as 5-O-methyl-allo-inositol. The structure was reconfirmed by acetate derivative (2).

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2013년도 춘계학술대회 논문집
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• pp.769-770
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• 2013

• Journal of applied mathematics & informatics
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• 제24권1_2호
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• pp.295-303
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• 2007

In this paper we investigate the boundedness character of the positive solutions of the rational difference equation of the form $$x_{n+1}=\frac{a_0+{{\sum}^k_{j=1}}a_jx_{n-j+1}}{b_0+{{\sum}^k_{j=1}}b_jx_{n-j+1}},\;\;n=0,\;1,...$$ where $k{\in}N,\;and\;a_j,b_j,\;j=0,\;1,...,\;k $, are nonnegative numbers such that $b_0+{{\sum}^k_{j=1}}b_jx_{n-j+1}>0$ for every $n{\in}N{\cup}\{0\}$. In passing we confirm several conjectures recently posed in the paper: E. Camouzis, G. Ladas and E. P. Quinn, On third order rational difference equations(part 6), J. Differ. Equations Appl. 11(8)(2005), 759-777.