In this paper, we investigated the relationship between the variables related to manufacturing environment and industrial accident. Also we wish to analyze how much these variables influence in production result of company: the manufacturing performances such as production quantity, quality, cost and delivery. For this investigation, we collected the real data from 16 small/medium-sized manufacturing companies by performing a questionnaire survey and one-site interview with the workers. Sixteen companies were made up of the following four industries: metal processing, machinery manufacturing, chemical products manufacturing and electronic products manufacturing, The data analysis was made using SPSS PC+. Based on the result of the analysis, we came to the conclusion that most of variables related to manufacturing environment and industrial safety were connecting with industrial accident occurrence and also influenced in manufacturing performance.