With the advancement of industrial development and diversification of workplaces development, the development of filtration technologies for capturing fine dusts and preventing facilities in workplaces that require specific management of various emissions, such as high temperature, high humidity, and acidic/alkaline conditions, has gained a large interest. Among several polymeric filtration materials, polytetrafluoroethylene (PTFE), commonly known as Teflon, is recognized for its excellent thermal stability, chemical resistance, and low coefficient of friction. However, these properties of PTFE pose challenges in conventional melt-blowing or electrospinning techniques and production processes for filtration materials. In this study, we successfully performed electrospinning by emulsifying granular PTFE powder into a heterogeneous polymeric solution and fabricated a nonwoven fabric composed solely of PTFE fibers through subsequent heat treatment. The developed PTFE nonwoven fabric consisted of fibers with a diameter of about 1.2 ㎛ and achieved superior heat stability, water resistance, chemical resistance, and tensile properties compared to conventional filtration materials. Moreover, it demonstrated excellent filtration efficiency with a pressure drop of 94.04% and 89.84 Pa, respectively, and confirmed its potential as an industrial filter that can be utilized in extremely harsh environments.