We describe a heterogeneous simulation framework, so called DEVS-HLA, in which conventional simulation models and the DEVS (Discrete Event System Specification) models are interoperable. DEVS-HLA conceptually consists of three layers: model layer, DEVS BUS layer, and HLA (High Level Architecture) layer. The model layer has a collection of heterogeneous simulation models, such as DEVS, CSIM, SLAM, and so on, to represent various aspects of a complex system. The DEVS BUS layer provides a virtual software bus, DEVS BUS, so that such simulation models can communicate with each other. Finally, the HLA layer is employed as a communication infrastructure, which supports several good features for distributed simulation. The DEVS BUS has been implemented on the HLA/RTI (Run-Time Infrastructure) and a simple example of a flexible manufacturing system has been developed to validate the DEVS-HLA.