1. 전신가토(全身家兎) 및 척수가토(脊髓家兎)에서 MAO 억제하(抑制下)에서의 brethylium의 tyramine 승압효과(昇壓效果)에 미치는 영향(影響)을 관찰(觀察)하였다. 2. 전신가토(全身家兎) 및 척수가토(脊髓家兎)에서 bretylium 정주(靜注) 후(後)에는 tyramine의 승압효과(昇壓效果)는 강화(强化)되었으나 MAO 억제제(抑制劑)인 catron을 정주(靜注)하고 bretylium을 추가(追加) 주입(注入)한 후(後)에는 tyramine의 승압효과(昇壓效果)는 catron 투여전(投與前)의 그것보다 감약(減弱)되었다. 3. Bretylium에 의한 tyramine 승압효과(昇壓效果)의 강화(强化)는 MAO 억제작용(抑制作用)으로 설명(說明)되고, tyramine 승압효과(昇壓效果)의 감약(減弱)은 교감신경말단(交感神經末端)의 차단작용(遮斷作用)으로 설명(說明)된다.

In Korea, life insurance policies are sold to the policy holders by insuring either the insureds undergo a medical examination at a clinic or the insureds' report their history of diseases ever experienced that replaces the medical examination. This study aimed to measure the level of death rates for the insureds between those who received medical examination and those who did not receive medical examination, and to examine differences of the rates in terms of the insureds' characteristics such as age, sex, cause of death and duration. A total number of 32,358 insureds were selected for the population of this study from the D. Life Insurance Company located in Seoul City. Out of the 32,358 insureds, 2,997 received medical examination and the rest of 29,381 did not received any medical examination. Results of analysis are summarized as follows: 1. Death rate per 100,000 insureds for the all was 19.3 in the first year, 96.3 in the second year, 143.8 in the third year 93.4 in the fourth year. For the group of medical examination received, the rate was zero in the first year, 41.3 in the second year, 55.4 in the third year and 268.8 in the fourth year, and for the group of non-medically examined the rate was 21.3 in the first year, 101.9 in the second year, 152.2 in the third year and 76.8 in the fourth year. The levels of death rates between the insureds with medical examsination and the inureds without medical examination were non-significant in the differences by duration except the levels of the third year, which indicated the death rate of non-medically examined group was higher than that of the medically examined group. 2. 73.0 per cent of the total deaths observed during the insured period were caused by various diseases and the rest of 27.0 per cent deaths were due to accidents. For the group of medical examination received, 55.6 per cent deaths were caused by diseases, and for the group of nonmedically examined, 74.7 per cent of deaths were due to diseases. 3. cancer was the most frequent cause which accounted for 22.0 per cent of the total deaths. Proportion of deaths due to cancer from the group of medical examination received was 22.2 per cent, and the corresponding rate for the group of non-medically examined also showed high rate of 22.0 per cent.

The serum total cholesterol levels were measured by Rosenthal modified method for the insured persons who had passed the medical examination in a life insurance company, Seoul. The sera were obtained from 1,878 adults, 626 males and 1,252 fermales, from sep 1980 to Dec. 1981. The results obtained in the measurement were as follows; 1. The mean and standard deviation of serum cholesterol level in the healthy insured persons were $163{\pm}$ in male, and $157{\pm}24mg%$ in female. The difference of the values between male and female showed statistical signifi- (p<0.01). With regard to sex and age differences, female were significantly higher than male in the 10's, and male were higher than female in the 20's and 50's between both sexes. 2. The cholesteol of male was gradully increased about 12mg% according to the increase of every 10-year interval, but no increase was observed from the 40's to the 50's. The cholesterol level of female was higher in the 10's than in the 20's, and was increased gradually from the 20's to the 50's. 3. No significant difference in serum total cholesterol levels between the insured persons and other normal Korean groups was observed; the frequency distribution of the cholestrol level for the population showed normal distribution.

Among the person who want to insure, there are not only fair persons who want to become the insurance with not realizing that one was not infected with certain disease but also someones on purpose to overcome the disease through the insurance company with be recognized by oneselves. However, it was found that the ultrasonography and exact effects of medical examination with the existing medical equipments of the insurance company could not be expected. We present some several proven examples for the purpose of getting the advanced effects in medical examination by utilizing the ultrasonic device which is not harmful to human body presently as far as known. We could find affirmation through the check of ultrasonography from 907 cases, in our Department of Medical selection that many portion of the cases checked the medical examination have the present condition of illness even though they enjoy social life with good health and finally the conclusions we have learned are as follows; The aged cases show the increase of rate of possessing disease and man shows 2.2 times of possessing disease than woman. Fatty infiltration of liver take portion of 74.7% from the case checked. 12 cases of cholelithiasis are not conscious of symptom at all. Through the check of ultrasonography in obstetrics and gynecology, myoma uteri be showed high rate of 72.2% from the case of possessing disease. In Case of the potential pregnancing woman it made clear to find pregnancy which was undistincted still more also know the existence and nonexistence of fetal death when pregnancy expected.

In the 2,218 healthy cases-male 1,574 female 644-who were conducted serum examination from May 1st 1983 to November 1st 1983 by the medical selection of Dae Han Kyouk life insurance Co., the results which investigated the HBsAg by using the Reverse Passive Hemagglutination(RPHA) method are as follows; 1. The number of 167 from 2,218 cases proved to be positive, showing 7.52%, the number of 143 from 1,574 male positive, showing 9.08%, and the number 24 from 644 female positive, showing 3.73%. The positive rate of the male was indicated by 5.36% higher than that of the female as the former marked 2.4 times higher distribution than the latter. 2) The positive rate by the type of occupations appears as follows; The highest positive rate group is that of discharger from military service in 1983, the number of 70 from 736 persons marking 9.51% and the next is the merchant 8.79%(8/91), employee of a company markes 8.53%(44/516), high school boy 7.69%(19/247), house wife 5.71%(10/210), carrier woman 3.45%(10/290) and the group of the high school girl records the minimum rate of all, 3.13%(4/128). 3. The positive rate by the age group appears as follows; The highest rate group is that of 31 to 35 years, marking 9.80% positive rate, and the next is $26{\sim}30$(9.3%), $21{\sim}25$(8.01%), $41{\sim}45$(6.96%), $36{\sim}40$(6.9%), those below 20(5.99%), 46 to 50 years shows the minimum rate of all(2.94%) Among the male case, 26 to 30 years shows the highest positive rate by 10.59% and female, 31 to 35 years shows the highest rate by 7.89%. 4. The positive rate by the blood type represents as follows; Blood type A shows 7.30%, type B 7.17%, type O 6.11% and type AB indicates 5.88% in order.

We've reviewed 5,067 cases of claims by death that had occured for about 5 years from January, 1979 to October, 1983. As a result, We came to following conclusions; First, the greater part of deaths above mentioned were due to the Disease of Adult such as the Malignant neoplasm(18.4%), a Heart disease(10.4%), Liver cirrhosis(9.1%) and the Cerebrovascular disease(7.6%) as well as Accidental Death(26.5%), which were occupied by 72% of the whole. Second, classifying them by medical examination or non-medical, deaths in case of non-medical examination showed 80.8% of the. whole. And for age, sections ranging from 40 to 49 and from 30 to 39 took the overwhelming portions by 36.9% and 29.8% respectively, both of which showed 66.7% of the whole. Third, for the period elapsed, deaths within 1 year from the entrance showed 21.3% and that from 1 years to under 2 years, 19.9%. Thus the rate of early death under 2 years stood for 41.2% of the whole. Fourth, for occupation of the insureds, commerce occupied 20.4%, company employees 14.4%, agriculture 13.3%. These three categories marked 48.8% of the whole. From this, it appeared that the accidental death rate of the insured with the risky occupation was much greater than orthers.