This thesis is consisted of studying of the medical literature about Five sense of organs. Five sense of organs are the eyes, tongue, mouth, nose and ears. Five sense of organs are performed human senses which external sensory information by accepting an important feature for maintaining the biological activity to be performed. The contents was compiled up to the Donguibogam to Chinese literature and documents encompass the Korea medical literature, Donguibogam related to the senses to identify the citation of each chapter, the actual quotation through doctrine and other publications revealed that the citation is to investigate how accurately identified through studying the analysis and observation. It is as following as I observed carefully the senses of Donguibogam quotations related to each other through doctrine and publishment institution follows in order of dynasties. There are four volumes of Han-dynasty, one volume of Weijinnanbei-Era, two volumes of Tang-dynasty, nineteen volumes of SongJinYuan-dynasty, seven volumes of Ming-dynasty as Chinese medical literature. There are four volumes of Chosun-dynasty as Korean medical literature. It is the most quotation publishment that the books of SongJinYuan-dynasty of above thirty-six-volume. It is the latest quotation book that is Gujinyigan in Chinese medical literature and Euirimchwalyo in Korean medical literature. It is very positive quotation considering even Donguibogam publishment year in 1613. The reference books are four volumes of Chosun-dynasty as Korean medical literature and thirty-two-volume of Chinese medical literature. By observing the quotation frequency, 157 times in Sheyideaiofang, 115 times in Yixuerumen, 74 times in Yixuegangmu, 39 times in Wanbinghuichun, 31 times in Euibangryuchwi, 30 times in Renzhezhizhifang and Gujinyigan, 28 times in Danxixinfafuyu, 23 times Hwangdineijing, 17 times in Nanshibizang and Yixuezhengchuan. Other else books have been cited less than 10 times. It might be made error that did not find the source of the books even though cited reference, also even though defining the source of reference it is only rare reference book. As mention above, there are a lot of discovering as the feature of reference Publications. Most of all we could find out the reference literature cited in Donguibogam, however we couldn't clarify other books in original books. Thus, we should remember that it did not coincide with cited marks when studying the Donguibogam.