Objectives: The purpose of this study was to identify the mediated effect of social support in relationship of stress and mental health of woman college students. Methods: Data were collected by distributing self recording type questionnaire to 336 woman students in three universities placed in Gyeonggi-do, who agreed attending to the research, and then were re-collected. The statistical methods used for data analysis were the descriptive statistics, frequency analysis, One-way ANOVA test, Pearson correlation coefficient, hierarchial regression analysis. Results: 1. According to the research, it appeared that social support differed depending on the grade the one is in(F=10.643, p<0.05), and mental health(F=3.446, p<0.05) and social support(F=2.444, p<0.05) differed depending on the family's economical level. 2. As the result of analysis of relationship of objects' mental health, stress, and social support, it appeared that mental health and stress(r=-0.605, p<0.01), mental health and social support(r=0.276, p<0.01) have relationship to each other. 3. As the result of hierarchial regression analysis for verifying the mediated effect of social support in relationship of research objects' stress and mental health, it showed that social support partially mediate in relationship of stress and mental health. Conclusion: The program which can intensify woman college students' social support and decrease stress needs to be developed and provided, in order to arrange solution of promoting woman students' mental health.