Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Effects of Oil type on the Stability of Oil-in-Water Lipid Nanoemulsion

  • Lee, Seung-Jun (Department of Chemical & Biomolecular Eng., KAIST) ;
  • Han, Sa Ra (Department of Chemical Engineering, Soongsil University) ;
  • Jeong, Jae Hyun (Department of Chemical Engineering, Soongsil University) ;
  • Kim, Jong-Duk (Department of Chemical & Biomolecular Eng., KAIST)
  • Received : 2016.11.23
  • Accepted : 2016.12.16
  • Published : 2016.12.30
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Abstract

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

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References

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