• English & American cultural studies
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• v.18 no.2
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• pp.27-50
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• 2018

Old age is often compared as climbing mountains which requires walking out of breath, yet with wider vision. And it is also likened to the estuary where the river flows slowly and broadly into the open sea. Socially, old age has been regarded as a symbol of wisdom and reflection, and elderly people often take the role of sage who leads the community. On the other hand, the dementia, gray hair and wrinkles of old age were sometimes perceived as the decline of intellect and vitality. Especially, in the digital age in which technology makes people more sensitive to physical artificiality, the evaluation of the old age becomes more complex and obscure. In other words, some elderly people can not escape from Confucious convention of the elders first, which causes the denouncement by younger generations. On the other hand, some elderly people are becoming more adaptable to the trend of young people, emerging as the new elderly people. The anti-aging movement, early adaptation of IT, bioengineering regimen also strong for the advanced age. However, as the new elderly people are active in many fields of society, they also face intergenerational conflicts in some areas where remains the overlap between young people and them due to the limited openings in economy and culture. This study is a transdisciplinary research which can be called old age humanities. First of all, this paper looks at the aspects of lifestyles and intergeneration conflicts in old age in four Korean and Western literary works about the old people, and also searches how to improve the quality of the later life of old people, Overall, this paper aims to explore the way the old people can achieve the full life with the help of intergenerational dependency through building aging humanities and new communities for old people.

• 한국노년학
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• v.39 no.2
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• pp.199-211
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• 2019

The purpose of this study is to analyze leisure satisfaction and leisure performance according to whether elderly people are performing their preferred leisure activities. For the analysis, we used sample from the 6th (2015) panal data as Korean Retirement and Income Study(KReIS). The results of this study were as follows. First, the total data of 4,197 elderly (2,212 young-old and 1,985 old-old) were analyzed. As a result, weekday and weekend leisure time of the old-old (7.64 hours / 7.81 hours) than the young-old (6.83 hour / 7.39 hour) was increased and resting activites (over 70% of watching TV and listening to the radio) accounted for more than 80% of the both elderly leisure activities. Leisure performance were higher in old-old who did not perform preferred leisure activities during weekdays. Leisure performance on weekends was higher in old-old regardless of whether they had preferred leisure time. Average of leisure performance was high in both groups and they responded leisure satisfaction was moderate. In the case of need for leisure change, young-old was higher than oid-old regardless of preference leisure performance and day of the week. However, the responses of the both groups are closed to those that do not want to change. Based on the results of this study, it should be practiced such as develomenting program and introduction of health management system considering leisure constraints to improve leisure satisfaction and continuance of leisure activities for young-old and old-old. We also emphasize the need for a systematic survey scale that takes into account the qualitative aspects of leisure activities as well as the subjective factors influencing leisure participation.

• Journal of Embryo Transfer
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• v.33 no.4
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• pp.305-311
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• 2018

Gonadotropin releasing hormone (GnRH) centrally plays a role in control of the hypothalamic-pituitary-gonadal axis-related hormone secretions in the reproductive neuroendocrine system. In addition, hormone receptors like luteinizing hormone receptor (LHR) are important element for hormones to take effect in target organ. However, ageing-dependent changes in terms of the distribution of GnRH neurons in the brain and LHR expression in the acyclic ovary have not been fully understood yet. Therefore, we comparatively investigated those ageing-dependent changes using young (1-5 months), middle (11-14 months) and old (21-27 months) aged female mice. Whereas a number of GnRH positive fibers and neurons with monopolar or bipolar morphology were abundantly observed in the brain of the young and middle aged mice, a few GnRH positive neurons with multiple dendrites were observed in the old aged mice. In addition, acyclic ovary without repeated development and degeneration of the follicles was shown in the old aged mice than others. LHR expression was localized in theca cells, granulosa cell, corpora lutea and atretic follicle in the ovaries from young and middle aged mice, in contrast, old aged mice had few positive LHR expression on the follicles due to acyclic ovary. However, the whole protein level of LHR was higher in the ovary of old aged mice than others. These results are expected to be used as an important basis on the relationship between GnRH and LHR in old aged animals as well as in further research for reproduction failure.

• Biomolecules & Therapeutics
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• v.29 no.4
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• pp.399-409
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• 2021

1,2-Diacetylbenzene (DAB) is a metabolite of 1,2-diethylbenzene, which is commonly used in the manufacture of plastics and gasoline. We examined the neurotoxic effects of DAB in young and old rats, particularly its effects on hippocampus. Previously, we reported DAB impairs hippocampal neurogenesis but that the underlying mechanism remained unclear. In this study, we evaluate the toxicities exhibited by DAB in the hippocampi of 6-month-old (young) and 20-month-old (old) male SD rats by treating animals intraperitoneally with DAB at 3 mg/kg/day for 1 week. Hippocampal areas were dissected from brains and RNA was extracted and subjected to RNA-seq analysis. RNA results showed animals exhibited age-dependent sensitivity to the neurotoxic effects of DAB. We observed that inflammatory pathways were up-regulated in old rats but that metabolism- and detoxification-related pathways were up-regulated in young rats. This result in old rats, especially upregulation of the TREM1 signaling pathway (an inflammatory response involved in Alzheimer's disease (AD)) was confirmed by RT-PCR. Our study results provide a better understanding of age-dependent responses to DAB and new insight into the association between DAB and AD.

• Korean Journal of Child Studies
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• v.33 no.3
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• pp.131-148
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• 2012

This study examines the scientific concept development of young children in terms of the day-night cycle. The subjects consisted of 180 three-, four-, and five-year-old children from two kindergartens and one children's center located in Seoul and Jeju. Individual interviews were conducted to collect verbal and pictorial responses on the day-night cycle. The scientific concepts on the day-night cycle are classified five stages including : no recognition, egocentric concept, initial mental models, synthetic mental models, and scientific mental models. Using two-way ANOVA, scores for the types of concept on the day-night cycles were then analyzed according to both the ages and genders of the children. The results reveal the existence of significant differences in terms of the types of concept of young children according to age. Most three-year-olds children had no recognition. Most three, four, and five-year-old children revealed egocentric concepts. Four-year-old children revealed that were in the initial stages of experiencing the mental models and synthetic mental models of the day-night cycle. Five-year-old children revealed that they were in the early stages of experiencing the initial, synthetic, scientific mental models of the day-night cycle. The results suggest appropriate ways of science education for young children based on the development of scientific concepts of the day-night cycle.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1342-1349
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• 2013

This study was performed to investigate the factors which impact on the health-related quality of life of young-old(65-69 yr), old-old(70-79 yr), and oldest-old(80 yr or above) women in vulnerable elderly received home care service from public health centers in B city. The data were collected from 383 elderly women using structured questionnaires from September to November, 2010. Multiple regression with the SPSS WIN 18.0 program were used to analyze the data. There were statistically significant differences among young-old, old-old, and oldest-old women regarding the health-related quality of life, life satisfaction, cognitive function, frail condition. The models including life satisfaction, frail condition, cognitive function, perceived health status, number of chronic diseases were explained variance of the health-related quality of life elderly women differently like 42.8% of young-old, 28.9% of old-old, and 31.5% of oldest-old. Finally, frail condition and life satisfaction were predictors in explaining the level of health-related quality of life among vulnerable old women regardless of age. Based on the findings of the study, health promotion programs should be developed to improve health-related quality of life of vulnerable aged women according to age differences.

• Journal of the Health Care and Life Science
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• v.8 no.2
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• pp.155-163
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• 2020

The purpose of this study is to examine the current status of the Injury based on the 7th National Data on the National Health and Nutrition Survey, identify the relationship between general characteristics, safety awareness, health status, injury, and identify the factors that affect the occurrence of injury. The subjects were selected for the final analysis of 1,608data. For the analysis, frequency analysis, cross analysis, and multiple logistic regression analysis were performed. the results of the study show that in the young-old elderly, gender(woman), marital status(separated of divorced), lower the awareness of safety, body discomfort, sickness, and in-outpatient, Annual unmet medical service experienced are higher the occurrence of injury. Therefore, as a prevention education that lowers the incidence of injury. selective education is required for the Young-old and Old-old elderly, and legal penalties for drunk driving on various means of transportation and an integrated approach to strengthening and education is required.

• 한국노년학
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• v.39 no.4
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• pp.699-721
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• 2019

The purpose of this study was to examine and compare factors affecting the subjective life expectancy among the elderly, and to suggest health practice and social welfare service implications for later life. A total of 4,483 seniors from the 6th wave(2016) of the Korean Longitudinal Study on Aging (KLoSA) were used for analysis. The subjects were divided into three age groups: the young-old (n=2,106, 65~74 years), middle-old (n=1,803, 75~84 years), and oldest-old (n=574, 85 years and older). Control variables were sociodemographic factors and health status factors. Independent variables were health promotion behavior, cognition of public care, participating social activity, economic activity, and receiving basic pension. The data were analyzed using hierarchical multiple regression. The main results were as follows. Health promotion behavior was associated with the young-old. Social activities and economic activity were associated with the young-old and middle-old. Receiving basic pension had a significant impact on all age groups. In the middle-old, significant results were focused on socio-demographic and health status factors compared to other groups. The results of this study will provide basic data for the elderly policy and welfare service and will help to find and improve the important factors for the life of the elderly.

• Journal of Microbiology and Biotechnology
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• v.10 no.2
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• pp.272-274
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• 2000

Temperate bacteriophage P2 has a nonessential gene called old(overcoming lysoginization defection). In the presence of old, the growth of the host (Escherichia coli) with recBC- genotype is ingibited, and another bacteriophage, lambda, cannot superinfect. The Old protein has been shown to possess an exonuclease actibity. Three mutant P2s(old 1, old 17, old 49) which did gene was coned into expression vectors to produce hexahistidine-tagged proteins. The proteins were affinity-purified and shown to lose its exonuclease activity on both double-stranded and single-stranded DNA substrates. Thus, it was concluded that the lambda exclusion was related to Old's exonuclease activity.

• The Korean Journal of Community Living Science
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• v.15 no.2
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• pp.55-64
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• 2004

The purpose of this study was to examine the differences in skin temperature and thermal comfort of participants in a $19^\circ{C}$ room (the recommended room temperature in the winter) depending on age, sex and clothing weight. Subjects were divided into four groups (6 young males, 5 young females, 6 old males, 6 old females) and experimental trials consisted of three conditions: wearing underwear in a $19^\circ{C}$ room (19CUW), without underwear in a $19^\circ{C}$ room (19C), and without underwear in a $24^\circ{C}$ room (24C). The results indicated the following: 1) There were no significant differences in mean skin temperature based on age or sex, and the mean skin temperatures of the four groups were in the range of 32.4∼$34.0^\circ{C}$. 2) In the 19C condition, the skin temperatures of the hands and feet of old females were higher than those of the other three groups. 3) In terms of perceived thermal comfort, young females showed a tendency to feel the most uncomfortable. Both old and young groups agreed that the 24C condition was the most comfortable. 4) Relational coefficients between thermal comfort and skin temperatures were higher in the young group than in the old group. Furthermore, the perceived thermal comfort had a stronger relationship with mean skin temperatures than with local skin temperatures. 5) The mean skin temperatures of subjects who indicated they were 'comfortable' were in the range of 31∼$36^\circ{C}$ regardless of age or sex.