• Journal of Integrative Natural Science
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• v.4 no.4
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• pp.273-277
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• 2011

It's a threat for the public health that H1N1 (Influenza virus A) causes disease and transmits among humans. WHO (world health organization) declared that the infections caused by the new strain had reached pandemic proportions. The approved neuraminidase inhibitors (Zanamivir and Oseltamivir) and related investigative drug (BCX-1812) are potent, specific inhibitors of influenza A and B viruses. These drugs are highly effective to prevent influenza A and B infections. Early therapeutic use reduces illness duration and respiratory complications. Recently, we found one of the potent inhibitor of erystagallin A ($IC_{50}$ of 2.04 ${\mu}M$) for neuraminidase target, this inhibitor shows most similar structure to its natural substrate, sialic acid. Therefore, we chose 1l7f to get the receptor structure for docking study among many crystal structures. A docking study has been performed in Surflex-Dock module in SYBYL 8.1. In the present study, we attempt to compare the docking studies of pterocarpin and erystagallin A with neuraminidase receptor structure. In the previous report, the methoxy group of pterocarpin had H-bonding with Arg residues. The present docking results for erystagallin A showed the backbone of hydroxyl group shows significant H-bonding interactions with Arg152 and Arg292. The results showed that erystagallin A interacts more favorably with distinctive binding site rather than original active site. Therefore, we tried to reveal plausible binding mode and important amino acid for this inhibitor using docking and site id search calculations of Sybyl. The results obtained from this work may be utilized to design novel inhibitors for neuraminidase.

• Korean Journal of Materials Research
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• v.27 no.1
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• pp.48-52
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• 2017

In this study, we used I-V spectroscopy, photoconductivity (PC) yield and internal photoemission (IPE) yield using IPE spectroscopy to characterize the Schottky barrier heights (SBH) at insulator-semiconductor interfaces of Pt/$HfO_2$/p-type Si metal-insulator-semiconductor (MIS) capacitors. The leakage current characteristics of the MIS capacitor were analyzed according to the J-V and C-V curves. The leakage current behavior of the capacitors, which depends on the applied electric field, can be described using the Poole-Frenkel (P-F) emission, trap assisted tunneling (TAT), and direct tunneling (DT) models. The leakage current transport mechanism is controlled by the trap level energy depth of $HfO_2$. In order to further study the SBH and the electronic tunneling mechanism, the internal photoemission (IPE) yield was measured and analyzed. We obtained the SBH values of the Pt/$HfO_2$/p-type Si for use in Fowler plots in the square and cubic root IPE yield spectra curves. At the Pt/$HfO_2$/p-type Si interface, the SBH difference, which depends on the electrical potential, is related to (1) the work function (WF) difference and between the Pt and p-type Si and (2) the sub-gap defect state features (density and energy) in the given dielectric.

• Fire Science and Engineering
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• v.33 no.5
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• pp.140-148
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• 2019

In line with the "mandatory seismic design of fire protection facilities," development of design automation software is indispensable for improving the reliability and efficiency of seismic design. The seismic design automation software developed in this study is an automated S/W for seismic design of fire-fighting facilities, and functions such as automatic arrangement of anti-shake braces according to Korea National Fire Agency's Seismic Design Standards for fire-fighting facilities, output of seismic bracing calculation bills and automatic quantities counting. In addition, the seismic design automation software not only reduces the work speed by three times compared to the manual design of the designer, but also improves the reliability of the design by reducing the human error related to the design quantity such as the brace. In addition, in the seismic design method of fire protection facilities that have been approached conservatively, it was possible to perform the optimal seismic design by using computer algorithms for at least in the use of braces.

• The Journal of the Korea Contents Association
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• v.10 no.1
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• pp.213-221
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• 2010

The purpose of this study is to consider a social influence and fitness with related a ripple effect of media fortune-contents in digital age. This Work was studied by Q-methodology to approach in-depth and essential meaning about this study. The perception type of this study was divided into three types. Above all, in this study we investigate two points to us. Points of this study ; First, how the type of the perception is divided on the subjectivity about Media Fortune-contents in Digital Age? Second, what is a trait of character in same or different quality within these types? The result reveals three types that divided '1 : Scientific Appeal Type ; N=10', '2 : Value-depended Type ; N=7', '3 : Positive Preference Type ; N=3'. Those types found that there is very different type all over. In conclusion, it was found that general mass preferred and enjoyed positively on fortune culture, and were concerned about various a practical use and participation of media fortune-contents.

• Journal of Digital Convergence
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• v.14 no.12
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• pp.471-476
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• 2016

Recently, important information related with smart work such as office and video conference are handled in smart device quite a lot compare with before. Also, execution environment of smart devices is getting developed as open software environment. It brought convenience to download and use any kind of application software. By that, security side of smart devices became vulnerable. This paper will discuss characteristics of smart device security technology based on virtualization that is a mobile device platform with isolated secure execution area based on TEE (Trusted Execution Environment). Also, this paper will suggest an implementation method about safe smart device security platform based on domain separation for application software which can be executed in smart devices. The domain separation based smart device security platform technology in this paper blocks unauthorized access and leakage of sensitive information in device. Also it will be the solution can block transmission and execution of malicious code in various area including variety of IoT devices in internet rather than just smart devices.

• Journal of Digital Convergence
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• v.18 no.9
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• pp.337-342
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• 2020

Art work based on computer and internet media technologies such as digital art, computer art, internet art, interactive art. Through examples, we studied the interaction and communication method between the audience and the exhibition objects. It was confirmed that the new media works are expressed in a new form by fusion with various technologies of experimental propensity, and research and analysis of overseas media-related exhibition cases and interactive media use cases of works exhibited at the 'Media City Exhibition' in Korea were conducted. Was able to confirm the main characteristics of new media art. I think it will be a more meaningful study by setting specific criteria and focusing on the fields of application of new media art and comparing and analyzing the future values of the times.

• Advanced Composite Materials
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• v.17 no.3
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• pp.277-299
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• 2008

High quality and expedient processing repair methods are necessary to enhance the service life of bridge structures. Deterioration of concrete can occur as a result of structural cracks, corrosion of reinforcement, and freeze.thaw cycles. Cost effective methods with potential for field implementation are necessary to address the issue of the vulnerability of bridge structures and how to repair them. Most infrastructure related applications of fiber-reinforced plastics (FRPs) use traditional hand lay-up technology. The hand lay-up is tedious, labor-intensive and relies upon personnel skill level. An alternative to traditional hand lay-up of FRP for infrastructure applications is Vacuum Assisted Resin Transfer Molding (VARTM). VARTM uses single sided molding technology to infuse resin over fabrics wrapping large structures, such as bridge girders and columns. There is no work currently available in understanding the interface developed, when VARTM processing is adopted to wrap fibers such as carbon and/or glass over concrete structures. This paper investigates the interface formed by carbon fiber processed on to a concrete surface using the VARTM technique. Various surface treatments, including sandblasting, were performed to study the pull-off tensile test to find a potential prepared surface. A single-lap shear test was used to study the bond strength of CFRP fabric/epoxy composite adhered to concrete. Carbon fiber wraps incorporating Sikadur HEX 103C and low viscosity epoxy resin Sikadur 300 were considered in VARTM processing of concrete specimens.

• Journal of the Ergonomics Society of Korea
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• v.26 no.2
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• pp.35-44
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• 2007

Work-related musculoskeletal disorders (WMSDs) are a major problem in industries in which manual materials handling is performed by workers. To prevent these WMSDs, it is necessary to understand the muscular strength capability and use this knowledge to design job and selection and assignment of workers. Even though two-hands lifting activity of manual materials handling tasks are prevalent at the industrial site, many manual materials handling tasks which require the worker to perform one-hand lifting are also very common at the industrial site and forestry and farming. However, a few researches have been done for one-hand lifting activity of manual materials handling tasks. The objective of this study is to compare one-hand and two-hands lifting strength in terms of static and dynamic strength of the lifting activity for the ranging from the height of knuckle to elbow. It is shown in this study that the isometric lifting strength of one-hand is ranging from 54.7 to 63.3% of the one of two-hands. However, it is found that there is no significant difference between a person's isometric lifting strength for left-hand and right-hand. It is also shown that there is no significant difference between the peak force under the dynamic sub-maximal loading with one-hand and two-hands lifting activity. Similar results were obtained for the peak acceleration and peak velocity under the dynamic sub-maximal loading with one-hand and two-hands lifting activity. Isometric lifting strength at the height of knuckle was ranging from 2 to 3 times of the dynamic peak force during sub-maximal lifting. It is concluded that the dynamic peak forces under the sub-maximal loading are not highly correlated with the isometric lifting strength in similar postures.

• Journal of Institute of Control, Robotics and Systems
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• v.12 no.1
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• pp.47-53
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• 2006

Localization is a essential technology for mobile robot to work well. Until now expensive sensors such as laser sensors have been used for mobile robot localization. We suggest RFID tag based localization system. RFID tag devices, antennas and tags are cheap and will be cheaper in the future. The RFID tag system is one of the most important elements in the ubiquitous system and RFID tag will be attached to all sorts of goods. Then, we can use this tags for mobile robot localization without additional costs. So, in this paper, the smart floor using passive RFID tags is proposed and, passive RFID tags are mainly used for identifying mobile robot's location and pose in the smart floor. We discuss a number of challenges related to this approach, such as tag distribution (density and structure), typing and clustering. When a mobile robot localizes in this smart floor, the localization error mainly results from the sensing range of the RFID reader, because the reader just ran know whether a tag is in the sensing range of the sensor. So, in this paper, we suggest two algorithms to reduce this error. We apply the particle filter based Monte Carlo localization algorithm to reduce the localization error. And with simulations and experiments, we show the possibility of our particle filter based Monte Carlo localization in the RFID tag based localization system.

• Korea journal of population studies
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• v.20 no.2
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• pp.43-66
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• 1997

This work examines reemployment processes through the use of event history unemployment data in the United States. Two aspects of these processes, the duration of unemployment and changes in the reemployment rate, are modelled and analyzed in terms of individual characteristics and their structural positions in the labor market. The secondary labor market is a competitive market in which unemployment occurs because people quit their jobs to devote more time in search for better jobs. Using search theory, the rate of reemployment has a positive time dependence as the searcher lower her reservation wage with the passage of time. By contrast, the primary market is characterized by long-term employment relations which reduce voluntary turnovers but generate layoffs temporarily. Relying on contract theory, because workers on temporary layoffs wait for recall, reemployment rates have a constant time dependence. Empirical results of unemployment durations indicate that reemployment processes are influenced by individual's positions in dual labor market structures. While the analysis suggests that the amount of search reemployment seems to be positively related to the degree of competitiveness of a market, somewhat weaker results are noted in the search reemployment processes in competitive markets.