High-fructose corn syrup (HFCS) is widely used as sweetener, and its overconsumption is become a major health problem. In the present study, we used adult female rats and applied a 28 days HFCS feeding model to monitor the estrous cycle and changes in tissue weights and histology. Adult female rats were divided into three groups. Animals were fed with ad libitum normal chow and (1) 24 hours tap water (Control group), (2) 12 hours HFCS access during dark period and 12 hours tap water (12H group), and (3) 24 hours HFCS only access (24H group). Total exposure period was 28 days. There is no significant change in body weight between control and HFCS-fed animals. Both absolute and relative weights of ovary in 24H animals were significantly heavier than those in control or 12H animals. The absolute and relative weights of the kidney and liver in 24H groups were significantly heavier than those in control or 12H animals. The estrous cycles of the 24H animals were significantly longer. Histological analyses revealed that 24H ovaries were relatively bigger and possessed more corpus lutea than control ovaries. Uterine sections of 12H and 24H animals showed a well-developed stratum vasculare between inner and outer myometrial layers. The number of endometrial glands were decreased in 12H uteri, and recovered in 24H uteri compared to control. Numbers of convoluted tubule in distal region increased in 12H and 24H kidney samples. Liver specimens of 12H and 24H showed the increased number of fat containing vacuoles. In conclusion, our study demonstrated that HFCS treatment for 28 days could induce (1) changes in length of estrous cycle with extended estrous and diestrous stages, (2) altered ovarian and uterine histology, and (3) liver and renal lipid accumulation. These findings reveal the adverse effects of HFCS drinking on the reproductive function and lipid metabolism of female rats.
After large-scale flooding damage occurred along the Imjin river in 1996, 1998, and 1999, the Hantan river flood control dam was planned, and it has since been under construction. Unlike existing dams in Korea, the Hantan river flood control dam will remain fully open except during high floods, when the dam will store flood water temporarily to reduce flood peaks and flood water volume downstream. During past flooding seasons, floating debris has caused difficulties in the management of large-scale dams. Most of the existing multipurpose dams in Korea have installed nets to collect floating debris based on many years of experience with and data about inflow and distribution of floating debris in the dams. For the Hantan river flood control dam, however, collection of data about inflow and distribution of floating debris is not possible as the dam is located near the border area between North and South Korea. In order to devise a preliminary plan to collect floating debris in the Hantan river flood control dam, an EFDC hydrodynamic model was used to analyze the behavior of floating debris during high floods. The Lagrangian particle tracking method was utilized to simulate the behavior of floating debris in the dam. Based on the analysis of paths and final destinations of the particles, seven collection points were selected where it seemed to be effective to collect floating debris, as debris is likely to accumulate there in high density.
Objectuves : The purpose of this study was to investigate the effects of Cheunghyeoltang(CHT) and Gami-Cheunghyeoltang(GCHT) on the obesity in rats. Methods : After we divided rats into four different groups, we Provided to normal group general diet and distilled water, to control group high fat diet and distilled water, to CHT group high fat diet and CHT and to GCHT group with high fat diet and GCHT for 9 weeks. Afterward we check the change of body weight, the concentration of AST, ALT, total cholesterol, HDL-cholesterol, LDL-cholesterol, the Atherogenic index and the gene expression of leptin in rats. Results : The increase of body weight were suppressed significantly in the CHT group and GCHT group in comparision with control group, the serum ALT showed significant decrease in the GCHT group in comparison with control group, the serum total cholesterol showed significant decrease in the CHT and GCHT group in comparison with control group, the atherogenic index(AI) showed significant decrease in the GCHT group in comparison with control group and the serum leptin showed increase of gone expression in the GCHT group in comparison with control group. Conclusions : According to the experimental results, it is suggested that CHT is effective to the suppression of body weight's increase, the improvement of hyperlipidemia and the activation of leptin's gene expression, GCHT is effective to the suppression of body weight's increase, the improvement of hyperlipidemia, the decrease of arteriosclerosis and the activation of leptin's gene expression. Therefore CHT and GCHT seem to be applicable to obesity, arteriosclerosis and hyperlipidemia in clinical practice.
The conductivity test is a measure of electrolytes leakage from plant tissue. The shorter the maturation period after heading was the greater electrical conductivity (EC) of rice seed. The polymer-coated seed was not different in EC compared with non-coated seed. As soaking time of rice seed increased, EC increased gradually. The EC varied from 9.9 to 20.7$\mu$S $cm^{-1}g^{-l}$ for control plots and from 21.3 to 41.7$\mu$S $cm^{-1}g^{-l}$ for heat-killed seeds which were produced by autoclaving seeds at 121$^{\circ}C$ for 20 minutes. The germination speed (the rate of 5th day) of rice seed was 94% at control plot, 83% at low temperature and 20% at high temperature. Besides, germination percentage was 95% for the control, 92% for the low temperature treatment and 39% for the high temperature treatment. The EC was negatively correlated (r=-0.771$^{**}$) with germination percentage at low temperature. Water uptake in seeds of 30, 40, 50 days after heading (DAH) was greater than that of 20 DAH. Plant height of seedlings was 9.84 cm for the control but 4.32 cm for the high temperature treatment, and the tallest for polymer-coated seed. Dry weight of seedlings was 0.841 g for the control and 0.287 g at high temperature. Besides, the polymer-coated seed was heavier than non-coated seed. The number of roots was largest from 40 to 50 DAH and polymer-coated seed, but was decreased from 20 to 30 DAH. The length of roots was 20.52 cm at control plot and 19.89 cm polymer-coated seed but 8.68 cm for the low temperature treatment and 7.28 cm for the high temperature treatment.
This study was conducted to determine the effect of L. casei KCTC 3109 on physico-chemical characteristics and TBARS values of fermented pork meat. Each pork meat were allotted to two treatments ; Control (0%), $T_1$ (supplemented with L. casei KCTC 3109 10%). The pH tenderness and water holding capacity (WHC) of $T_1$ were higher than those of control (p<0.05), cooking loss of control was higher than $T_1$. Water content, crude Int and ash were not significantly different crude protein was higher in $T_1$ compared with control (p<0.05). $L^*,\;a^*$ and $b^*$ values of control were higher than those of $T_1$ (p<0.05). TBARS values was higher in $T_1$(0.02 MA mg/1,000 g) than control (0.19 MA mg/1,000g) (P<0.05).
Journal of the Korean Society of Food Science and Nutrition
/
v.28
no.1
/
pp.233-239
/
1999
This study was performed to evaluate the effects of the supplementation of lactic acid bacterias (LAB; S. thermophilus, L. acidophilus) aluminum accumulation and function kidney in rats treated with 250 g/g aluminum sulfate for 4 weeks. Fifty male Sprague Dawley strains were divided into five groups according to the types of supplement. the control, S. thermophilus culture group(A), autoclaved S. thermophilus culture(B), L. acidophilus culture group(C) and autoclaved L. acidophilus(D). The weight gain was increased by supplementation of S. thermophilus culture(A), autoclaved S. thermophilus culture(B), L. acidophilus culture(C), autoclaved L. acidophilus culture(D), especially by supplementation of S. thermophilus cultured(A) as compared to control group. The amount of water intake was increased in control group as compared to the LAB supplemented group. The content of aluminum were decreased 19.57%, 31.25%, 37.10%, and 32.40% in kidney after supplementation of non autoclaved culture group (A,C), and autoclaved group(B,D) respectively, as compared to control group. Water balance, urine volume, and excretion of sodium and potassium decreased in LAB supplemented group and control group. Excretion of creatinine increased in control group and tendency to increased in LAB supplemented group. In conclusion, the effect of suppression of aluminum accumulation was more effective in sup plementation of S. thermophilus culture(A), and L. acidophilus culture(C) than autoclaved S. thermo philus culture(B), and L. acidophilus culture(D).
Kim, Soon-Dong;Lee, Shin-Ho;Kim, Mee-Jung;Oh, Young-Ae
Journal of the Korean Society of Food Science and Nutrition
/
v.17
no.3
/
pp.255-261
/
1988
For the purpose of fermentation control and edible period extension of lower salted Kimchi, the contents and compositions of pectic substances in Kimchi, by adding 2 percent salt and 0.4 percent sodium malate buffer(SMB), fermented at $20^{\circ}C$ were investigated. Edible period of SMB added chinese cabbage Kimchi was extended 40 hrs compared to that of control (added 2.5% salt) with good flavor, texture and freshness. The contents of alcohol insoluble solid(AIS) and protopectin(PP) of control were more decrensed during fermentation than those of SMB added Kimchi. But, the contents of pectic adid(PA) and water soluble pectin(WSP) of control were more increased during fermentation than those of SMB added Kimchi. Hexose and pentose from hemicellulose in control, PP and PA respectively, were more decreased during fermentation than those in SMB added Kimchi. Lower polarity and higher molecular weight PP was eluted and higher polarity and lower molecular weight PP was decreased considerably in control compared to those in SMB added Kimchi during fermentation.
Bobitang(BBT) is one of the most important prescription that has been used in oriental medicine(dongyibogam) for recovering spleen condition. The study was done to evaluate effects of BBT water extract on the spleen lipid peroxide content and metabolic enzyme system changes. After pretreatment of BBT I (100mg/kg), BBT II(250mg/kg), BBT III(350mg/kg), BBT IV(500mg/kg) for 1 week, lipid peroxide content and metabolic enzyme system changes of the spleen was measured in 8 months rats. The results were obtained as follows : 1. The content of spleen lipid peroxide was significantly decreased in all experimental groups as compared with control, and best in BBT III IV treated groups. 2. The activity of spleen superoxide generation was significantly decreased in all experimental groups as compared with control, and best in BBT IV III treated groups. 3. The activity of cytochrome P-450 and aminopyrine demethylase wasn't significant change. 4. The activity of aniline hydroxylase was significantly decreased in BBT IV II treated groups, xanthine oxidase was significantly decreased in all experimental groups, aldehyde oxidase was significantly decreased in BBT IV treated group as compared with control. 5. The activity of antioxidant enzymes as superoxide dismutase, catalase, glutathione peroxidase was significantly increased in all experimental groups as compared with control. 6. The activity of glutathion S-transferase was significantly increased in all experimental groups, the concentration of spleen glutathione was significantly increased in BBT IV treated group as compared with control. 7. The activity of ${\gamma}$ -glutamylcystein synthetase was significantly increased in BBT III IV I treated groups as compared with control, the activity of glutathione reductase wasn't significant change. From the above results, BBT is cosidered to have effect of remove peroxide content and free radical that was made during ageing process. It is expected that treatment of BBT can be applied in future clinical study of delaying the ageing process.
Journal of the Korean Society of Industry Convergence
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v.24
no.6_2
/
pp.801-808
/
2021
In this paper, a numerical analysis was conducted on the effect of the flow control valve of a oscillation water column(OWC) type wave power generator turbine. The OWC wave power turbine operates with compressed air in the air chamber according to the change of wave height. When the wave height changes rapidly, a flow control valve is required due to overload of the turbine and reduced efficiency. Therefore, in this paper, a flow control valve with an opening angle of 60 degrees was installed in the front of the turbine, and the pressure drop, torque, and overall performance were calculated according to the change of turbine RPM and flow rate of turbine inlet. In conclusion, the flow control valve with an opening angle of 60 degrees affects when the turbine rotates at low rotation and the inlet flow rate is large. But it does not have a significant effect on overall turbine performance and it is necessary to find the optimal angle in the future works.
Objectives : This study was performed to investigate the effect of water extracts from Saengkankeonbi-tang on prevention of hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rats the control and Saengkankeonbi-tang groups with 25% alcohol for 55 days. For the same period we fed the Saengkankeonbi-tang group with Saengkankeonbi-tang extract as well and rats in normal and contrlo group on saline solution. We measured the serum components in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Saengkankeonbi-tang on prevention of hyperlipemia induced by alcohol. Saengkankeonbi-tang group showed significant decrease in total cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase in HDL-cholesterol levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. 2. At second, we observed effects of Saengkankeonbi-tang on prevention of liver damage induced by alcohol. Saengkankeonbi-tang group showed significant decrease in GOT, GPT, LDH and ALP levels in comparison with those of the control group. Saengkankeonbi-tang group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Saengkankeonbi-tang have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.
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