• Journal of Veterinary Science
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• v.22 no.1
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• pp.9.1-9.11
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• 2021

Background: Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives: This study examined the effects of bee venom (BV) stimulation on scalding burn injury-induced nociception in mice as a new treatment for burn pain. Methods: To develop a burn injury model, the right hind paw was immersed temporarily in hot water (65℃, 3 seconds). Immediately after the burn, BV (0.01, 0.02, or 0.1 mg/kg) was injected subcutaneously into the ipsilateral knee area once daily for 14 days. A von Frey test was performed to assess the nociceptive response, and the altered walking parameters were evaluated using an automated gait analysis system. In addition, the peripheral and central expression changes in substance P (Sub P) were measured in the dorsal root ganglion and spinal cord by immunofluorescence. Results: Repeated BV treatment at the 2 higher doses used in this study (0.02 and 0.1 mg/kg) alleviated the pain responses remarkably and recovered the gait performances to the level of acetaminophen (200 mg/kg, intraperitoneal, once daily), which used as the positive control group. Moreover, BV stimulation had an inhibitory effect on the increased expression of Sub P in the peripheral and central nervous systems by a burn injury. Conclusions: These results suggest that a peripheral BV treatment may have positive potency in treating burn-induced pain.

• Nano
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• v.13 no.10
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• pp.1850113.1-1850113.11
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• 2018

Environmental and energy issues have always been a hot topic of global research. Oil leakage has caused great damage to the environment, affecting a wide area and it is difficult to clean up. In most cases, carbon-based adsorbents are typically utilized to remove oil spills because of their economic benefits and high adsorbent efficiency. At the same time, its excellent material properties can also be used for the preparation of supercapacitors. In this paper, the carbon aerogels were prepared by the one-step method. The prepared materials endowed a 3D network structure with a huge number of micropores and mesoporous, and the material is light-weight, stable, hydrophobic and has affinity for oil (17.02 g/g) to the KGM carbon aerogel. Through the physicchemical characterization, the KGM carbon aerogel shows specific surface area is $689m^2/g$, high water contact angle ($136.64^{\circ}$) and excellent reusability (more than 15 cycle times). In addition, we also discussed the electrochemical properties of the material and obtained the specific electrical capacity of 139 F/g under the condition of 1 A/g.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.1
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• pp.10-16
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• 2019

In order to investigate the effects of Eucomiae Cortex extracts on the depression caused by aging, histochemistry and immunohistochemistry were performed on the hippocampus of aged rats and the following results were obtained. Experimental animals were divided into three groups as follows: 8 week old ICR male mice, Aging-elicited group (AE group) and Eucomiae Cortex treatment group (EC group) 50 week old male ICR mice were used. The control group and AE group did not take any treatment and did not restrict diets and negatives. In the EC group, 0.51g/kg of Eucomiae Cortex extract was dissolved in distilled water once a day for 6 months. The Eucomiae Cortex extract reduced pyramidal neuronal damage in C3 hippocampus and dentate gyrus, increased DJ-1, SHH positive responses in aged mouse hippocampus, and 8-OHdG positivity was reduced, ${\beta}$-endorphin positivity was reduced in aged mouse substantia nigra. Therefore, based on the above results, Eucomiae Cortex extract reduces damage of pyramidal neurons in the hippocampus caused by aging, inhibits neuronal cell death, induces proliferation and differentiation of stem cells in the hippocampus, reduces DNA damage-induced oxidative stress, so improves the reduction of hippocampus volume. It is also thought to improves depression due to aging through ${\beta}$-endorphin which enhances mood through the inhibition of pain.

• Korean Journal of Environmental Agriculture
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• v.37 no.3
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• pp.221-228
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• 2018

BACKGROUND: Spoilage fungi can reduce the shelf life of fresh fruits and cause economic losses by lowering quality. Especially, mulberry fruits have high sensitivity to fungal attack due to their high water content (> 70%) and soft texture. In addition, the surface of these fruits is prone to damage during harvesting and postharvest handling. However, any study on postharvest spoilage fungi in mulberry fruit has not been reported in Korea. This study aimed to examine the spoilage fungi occurring in mulberry fruits during storage after harvest. METHODS AND RESULTS: In this study, we isolated postharvest spoilage fungi from mulberry fruits stored in refrigerator (fresh fruits) and deep-freezer (frozen fruits) and identified them. In the phylogenetic analysis based on comparisons of the ITS rDNA sequences, the 18 spoilage fungi isolated from mulberry fruits and the 25 reference sequences were largely divided into seven groups that were subsequently verified by high bootstrap analysis of 73 to 100. Alternaria spp. including A. alternate and A. tenuissima, were the most frequently isolated fungi among the spoilage isolates: its occurrence was the highest among the 18 isolates (38.9%). CONCLUSION: The findings of this study will be helpful for increasing the shelf life of mulberry fruits through the application of appropriate control measures against infection by spoilage fungi during storage.

• Journal of the Korean earth science society
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• v.40 no.1
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• pp.9-23
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• 2019

Super-refraction of radar beams tends to occur primarily under a particular vertical structure of temperature and water vapor pressure profiles. A quality control process for the removal of anomalous propagation (AP) ehcoes are required because APs are easily misidentified as precipitation echoes. For this purpose, we collected X-band polarimetric radar parameters (differential reflectivity, cross-correlation coefficient, and differential phase) only including non-precipitation echoes (super-refraction and clear-sky ground echoes) and precipitation echoes, and compared the echo types regarding the relationships among radar reflectivities, polarimetric parameters, and the membership functions. We developed a removal algorithm for the non-precipitation echoes using the texture approach for the polarimetric parameters. The presented algorithm is qualitatively validated using the S-band Jindo radar in Jeollanam-do. Our algorithm shows the successful identification and removal of AP echoes.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.6
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• pp.1405-1410
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• 2018

The Ringer's Solution used in medical institutions is one of the injections helpful for recovering the body condition from fever or dehydration by supplying the water to the body. The medical staffs frequently check the amount of Ringer's Solution prescribed for the relevant patient to check the time for replacing the Ringer's Solution. However, currently, many nurses experience the excessive workload because of the insufficient workforce and lots of workload assigned to each of the nurses; so the they cannot provide the high-quality medical services to patients and guardians. In order to solve this problem, this thesis designed and realized the Ringer's Solution replacement time control system through the non-contacting sensor, IoT device using WiFi, and OCS interlock. Thus, this study is expected to be able to efficiently operate the Ringer's Solution replacement work and also to provide the high-quality medical service to patients and guardians by automatically notifying the timing of Ringer's Solution replacement to medical staffs, and omitting the inefficient intermediate step in the past.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.65-71
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• 2019

The propose of this study has been conducted to examine expression of c-Myc and Thymosin-${\beta}4$ in liver cirrhosis model from liver fibrosis and For the method of study, the experiment was conducted in 2 groups; liver cirrhosis model experiment group due to liver fibrosis and control group with distilled water. This study outcome showed that liver cirrhosis model experiment group had significantly higher expression of c-Myc and Thymosin-${\beta}4$. with changes to hepatic tissue of special staining and electron microscopy. In conclusion, in clinical tests regarding liver function, molecular evaluation of c-Myc and Thymosin-${\beta}4$ and their expression along with serological change and histological assessment can be utilized as a reference for diagnosing liver disease for prevention and diagnosis of the disease, Based on this research in the future, we will carry out an in-depth study by adding the types of experimental groups and related genes.

• Parasites, Hosts and Diseases
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• v.57 no.3
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• pp.257-264
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• 2019

We tried a series of morphological and molecular approaches to identify a new species of Stellantchasmus (Digenea: Heterophyidae) originating from the wrestling half-beaked fish, Dermogenys pusillus of Thailand. Adult worm samples of the new species were recovered from hamsters experimentally infected with the metacercariae from D. pusillus in Thailand. Two isolates (Thai and Korean) of Stellantchasmus falcatus were used as comparative control groups. Worm samples of 3 Stellantchasmus groups were morphologically observed and molecularly analyzed with the mitochondrial cytochrome c oxidase 1 gene. The morphological characteristics of S. dermogenysi n. sp. are similar to S. falcatus originating from brackish water fish, but minor difference was noted including the absence of the prepharynx, position of the ovary near the ceca end, smaller body size, and shorter esophageal length. A phylogenetic tree derived from neighbor-joining and maximum-likelihood methods suggests that S. dermogenysi n. sp. is separated from S. falcatus supported by high bootstrap values. The relative divergences persist between these host-specific trematodes, which we suggest should be recognized as 2 distinct species. Comparisons of S. dermogenysi n. sp. with S. falcatus isolated from mullets in Thailand and Korea indicate a genetic divergence of mitochondrial DNA of 19.4% and 21.7%, respectively. By the present study, a new species, Stellantchasmus dermogenysi n. sp. (Digenea: Heterophyidae), is proposed in Thailand based on molecular evidences, in addition to minor morphological differences between S. falcatus and the new species.

• Geomechanics and Engineering
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• v.18 no.5
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• pp.515-525
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• 2019

A karst collapse, as a natural hazard, is totally different to a normal collapse. In recent years, karst collapses have caused substantial economic losses and even threatened human safety. A risk assessment model for karst collapse was developed based on the fuzzy analytic hierarchy process (FAHP) and grey relational analysis (GRA), which is a simple and effective mathematical algorithm. An evaluation index played an important role in the process of completing the risk assessment model. In this study, the proposed model was applied to Jiaobai village in southwest China. First, the main controlling factors were summarized as an evaluation index of the model based on an investigation and statistical analysis of the natural formation law of karst collapse. Second, the FAHP was used to determine the relative weights and GRA was used to calculate the grey relational coefficient among the indices. Finally, the relational sequence of evaluation objects was established by calculating the grey weighted relational degree. According to the maximum relational rule, the greater the relational degree the better the relational degree with the hierarchy set. The results showed that the model accurately simulated the field condition. It is also demonstrated the contribution of various control factors to the process of karst collapse and the degree of collapse in the study area.

• Journal of the Society of Disaster Information
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• v.15 no.2
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• pp.214-222
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• 2019

Purpose: The purpose of this study is to develop a sprinkler head that can be controlled and initial suppressed by installing it in a rack-type warehouse. Method: Considering the spray radius and spray pattern, various deflectors were designed, and the spray angle, discharge characteristics and protection performance test was conducted, and these results were compared and analyzed. Results: An optimal sprinkler head was developed to protect full load, front side of a commodity with minimum water volume 115L/min. Conclusion: The developed head of K-115 and 1Bar pressure was tested with one tier storage confirming that the fire control is carried out without burning all the loadings. In addition, the vertical distance from the top of the load to the deflector shall be separated by 450mm and installed to allow sufficient discharge to the outer part of the commodity.