• Earthquakes and Structures
• /
• 제26권1호
• /
• pp.31-48
• /
• 2024

In order to get a better understanding of seismic performance of exterior beam-column joint, reciprocating loading tests with variable loading speeds or axial forces were carried out. The main findings indicate that only few cracks exist on the surface of the joint core area, while the plastic hinge region at the beam end is seriously damaged. The damage of the specimen is more serious with the increase of the upper limit of variable axial force. The deflection ductility coefficient of specimen decreases to various degrees after the upper limit of variable axial force increases. In addition, the higher the loading speed is, the lower the deflection ductility coefficient of the specimen is. The stiffness of the specimen decreases as the upper limit of variable axial force or the loading speed increase. Compared to the influence of variable axial force, the influence of the loading speed on the stiffness degradation of the specimen is more obvious. The cumulative energy dissipation and the equivalent viscous damping coefficient of specimen decrease with the increase of loading speed. The influence of variable axial force on the energy dissipation of specimen varies under different loading speeds. Based on the truss model, the biaxial stress criterion, the Rankine criterion, the Kent-Scott-Park model, the equivalent theorem of shearing stress, the softened strut-and-tie model, the controlled slip theory and the proposed equations, a calculation method for the shear capacity is proposed with satisfactory prediction results.

• Journal of Microbiology
• /
• 제45권6호
• /
• pp.572-577
• /
• 2007

To enhance therapeutic potential of murine monoclonal antibody, humanization by CDR grafting is usually used to reduce immunogenic mouse residues. Most humanized antibodies still have mouse residues critical for antigen binding, but the mouse residues may evoke immune responses in humans. Previously, we constructed a new humanized version (AKA) of mouse CC49 antibody specific for tumor-associated glycoprotein, TAG-72. In this study, to select a completely human antibody light chain against TAG-72, guided selection strategy using phage display was used. The heavy chain variable region (VH) of AKA was used to guide the selection of a human TAG-72-specific light chain variable region (VL) from a human VL repertoire constructed from human PBL. Most of the selected VLs were identified to be originated from the members of the human germline VK1 family, whereas the VL of AKA is more homologous to the VK4 family. Competition binding assay of the selected Fabs with mouse CC49 suggested that the epitopes of the Fabs overlap with that of CC49. In addition, they showed better antigen-binding affinity compared to parental AKA. The selected human VLs may be used to guide the selection of human VHs to get completely human anti-TAG72 antibody.

• International Journal of Industrial Entomology and Biomaterials
• /
• 제15권2호
• /
• pp.123-130
• /
• 2007

The Hsp 20.8 and Hsp 90 cDNA sequence retrieved from NCBI database and consists of 764 bp and 2582 bp lengths respectively. The corresponding cDNA homologus sequences were BLAST searched in Bombyx mori genomic DNA database and two genomic contigs viz., BAAB01120347 and AADK01011786 showed maximum homology. In B. mori Hsp 20.8 and Hsp 90 is encoded by single gene without intron. Specific primers were used to amplify the Hsp 20.8 gene and Hsp 90 variable region from genomic DNA by using the PCR. Obtained products were 216 bp in Hsp 20.8 and 437 bp in Hsp 90. There was no variation found in the six silkworm races PCR products size of contrasting response to thermal tolerance. The comparison of the sequenced nucleotide variations through multiple sequence alignment analysis of Hsp 90 variable region products of three races not showed any differences respect to their thermotolerance and formed the clusters among the voltinism. The comparison of aminoacid sequences of B. mori Hsps with dipteran and other insect taxa revealed high percentage of identity growing with phylogenetic relatedness of species. The conserved domains of B. mori Hsps predicted, in which the Hsp 20.8 possesses ${\alpha}-crystallin$ domain and Hsp 90 holds HATPase and Hsp 90 domains.

• 대한전자공학회논문지SP
• /
• 제41권5호
• /
• pp.111-116
• /
• 2004

웨이블릿 영역에서 Bayesian 추정법을 이용한 잡음 제거를 위해서는 웨이블릿 계수의 prior 모델, 잡음의 확률분포, 웨이블릿 계수에 대한 분산 등의 정보가 필요하다. 잡음 제거의 일반적인 방법은 웨이블릿 계수에 대한 적절한 prior 모델을 설정하고 이에 대한 신호의 분산을 추정하는 것이다. 본 논문에서는 영역 확장 방법을 사용하여 영상의 영역에 따라 분산을 추정하기 위한 창의 크기를 결정하는 방법을 제안한다. 이웃 계수의 범위는 동질성 척도를 정의하여 가장 작은 영역부터 영역을 확장하는 방법을 사용한다. 결정된 가변 이웃 영역을 사용하여 원 신호의 분산을 결정하고 이를 이용하여 웨이블릿 영역에서 Bayesian 추정법을 사용하여 영상의 잡음을 제거한다. 실험 결과를 통하여 제안 방법이 기존의 방법보다 높은 PSNR을 나타냄을 보여 준다.

• International Journal of Quality Innovation
• /
• 제1권1호
• /
• pp.89-96
• /
• 2000

Evolutionary operation (EVOP) is a continuous improvement system which explores a region of process operating conditions by deliberately creating some systematic changes to the process variable levels without jeopardizing the product. It is aimed at securing a satisfactory operating condition in full-scale manufacturing processes, which is generally different from that obtained in laboratory or pilot plant experiments. Information on how to improve the process is generated from a simple experimental design. Traditional EVOP procedures are established on the assumption that the variance of the response variable should be small and stable in the region of the process operation. However, it is often the case that process noises have an influence on the stability of the process. This process instability is due to many factors such as raw materials, ambient temperature, and equipment wear. Therefore, process variables should be optimized continuously not only to meet the target value but also to keep the variance of the response variables as low as possible. We propose a scheme to achieve robust process improvement. As a process performance measure, we adopted the mean square error (MSE) of the replicate response values on a specific operating condition, and used the Kruskal-Wallis test to identify significant differences between the process operating conditions.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2001년도 추계학술대회논문집 I
• /
• pp.419-426
• /
• 2001

Industrial products determined by fixed size posses definite limits variety by manufacture tolerance in existence. The optimum value solved by deterministic approaches do not account of tolerance bands of design variables and material properties. If we examine optimum value considering tolerance bands of design variables and material properties, it might be useless, owing to exist infeasible region. We have two ways to prevent being useless value. The one is to minimize tolerance band, the other is to consider tolerance band in optimum design. The former needed more accuracy during manufacturing process require higher production cost, the letter is more appropriate to consider tolerance band. In this research, we consider the tolerance bands of all variables, which might have the tolerance bands used in the problem, based on optimum value of deterministic approaches. Orthogonal arrays are used to minimize the number of trial. Tolerance bands are supposed discretionary according to design variable. Appropriateness suggested by this research is examined through two examples. Mathematical problem is investigated only in terms of tolerance bands of design variables, and cantilever beam problem is explained through tolerance bands of design variable, material properties and loading conditions. It is proved that values from the presented method are satisfactory for tolerance bands of variables.

• 대한원격탐사학회지
• /
• 제34권1호
• /
• pp.141-150
• /
• 2018

Crop type classification is essential for supporting agricultural decisions and resource monitoring. Remote sensing techniques, especially using hyperspectral imagery, have been effective in agricultural applications. Hyperspectral imagery acquires contiguous and narrow spectral bands in a wide range. However, large dimensionality results in unreliable estimates of classifiers and high computational burdens. Therefore, reducing the dimensionality of hyperspectral imagery is necessary. In this study, the Random Forest (RF) classifier was utilized for dimensionality reduction as well as classification purpose. RF is an ensemble-learning algorithm created based on the Classification and Regression Tree (CART), which has gained attention due to its high classification accuracy and fast processing speed. The RF performance for crop classification with airborne hyperspectral imagery was assessed. The study area was the cultivated area in Chogye-myeon, Habcheon-gun, Gyeongsangnam-do, South Korea, where the main crops are garlic, onion, and wheat. Parameter optimization was conducted to maximize the classification accuracy. Then, the dimensionality reduction was conducted based on RF variable importance. The result shows that using the selected bands presents an excellent classification accuracy without using whole datasets. Moreover, a majority of selected bands are concentrated on visible (VIS) region, especially region related to chlorophyll content. Therefore, it can be inferred that the phenological status after the mature stage influences red-edge spectral reflectance.

• 한국산학기술학회논문지
• /
• 제13권8호
• /
• pp.3654-3659
• /
• 2012

능동 윤곽 모델 혹은 스네이크는 영상처리 및 컴퓨터 비전 분야에서 널리 사용되는 분할 방법이다. 능동 윤곽 모델의 가장 큰 문제점은 초기에 설정하는 폐쇄 점들의 개수와 위치에 매우 민감하기 때문에 초기 설정에 따라 결과가 극명하게 달라진다는 것이다. 특히 풍선 형태의 능동 윤곽 모델의 경우 작은 크기에서 시작하여 윤곽선을 만날 때까지 발산하여 그 영역을 넓혀 가기 때문에 초기의 폐쇄 점들의 영역보다 훨씬 커질 경우 더욱 큰 문제점을 보일 수 있다. 본 논문에서는 이러한 문제를 해결하기 위해 폐쇄 점들 간의 거리에 따라 폐쇄 점들의 개수를 변화시킬 수 있는 새로운 알고리즘을 제안한다.

• 한국병원경영학회지
• /
• 제11권4호
• /
• pp.82-103
• /
• 2006

The purpose of this study is to analyse statistically the relation between medical service quality and managerial performance. And then the way of analysis is the regression analysis that independent variable is service quality, dependent variable is the volume of revenue, the number of patients and the rate of beds utility, and dummy variable is the number of beds, ownership and region. The sample hospitals were the 113 hospitals on general hospitals more than 300beds which were consisted of 20 public hospitals, 41 corporate hospitals and 52 college hospitals, and also distributed 67 hospitals on big city and 46 hospitals other city. The sample hospitals were selected from the Korean Hospital Association and the data of the year 2003 and 2004. The collected data was analyzed using the SPSSWIN 10.0 version, and the study hypothesis was tested using regression analysis. The findings of this study are summarized as follows. First, as a result of analysing hypothesis 1. In the study of the relationship between the service quality and the revenue, it was verified that the more service quality in last year became the more revenue in the year. But the dummy variable, ownership and region, rarely related to hospital revenue. Therefore it means that the more service quality is connected to the more revenue on the large number of beds hospitals. Second, as a result of analysing hypothesis 2 & 3. In the study of the relationship between the service quality and the number of patients, it was verified that the more service quality in last year became the more outpatients in the year. But there was no verified to inpatients. It seems to be the reason why a hospital has operated the fixed number of beds approved by the public office. So there are no free to expand beds according to the number of inpatients as much as inpatients are increasing. Third, as a result of analysing hypothesis 4 & 5. In the study of the relationship between the service quality and the rate of beds utility, it was verified that the more service quality in last year became the shorter of average stay of length in the year. Especially it has influenced much more on a hospital which was the large number of beds, the corporate and the college, but the region. But it was denied that the more service quality became the more the beds turnover. As a result of this study, it shows that the service quality in the last year has importantly influenced on a hospital managerial performance in the year. Estimating the service quality of each hospital, most patients have selected the hospital they want. And the hospital need to keep the number of patients for the proper management. So this result of the study means that a hospital must improve the service quality for keeping efficient management.

• 한국자동차공학회논문집
• /
• 제18권5호
• /
• pp.62-67
• /
• 2010

Exhausting fossil fuel and increasing concern of air pollution have brought on the change of the focus of developing new vehicles from performance to fuel economy and emission. The gasoline engines adopting the naturally aspirated way use the throttle-body for engine load control. Therefore, its pumping loss increases more than that of the diesel engine, and also mostly operating in a partial load condition has bad influence on fuel economy and emission. In these days, the continuous variable valve timing system and variable induction system are adopted in order to improve fuel consumption and emission. In this study, we optimize the runner length and operate region of variable induction system to simulataneously improve the performance, fuel economy, and emission of gasoline engine with employing GT-Power as a CAE tool for engine analysis and PIAnO as PIDO tool for process integration and design optimization.