• Journal of Veterinary Science
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• 제23권1호
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• pp.6.1-6.8
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• 2022

Background: With limited information available, the association among urinary tract infections, urease-producing bacteria and the presence of magnesium ammonium phosphate (MAP) urolithiasis in canines in Thailand requires more study. Objectives: This study aimed to investigate the association between demographic characteristics of canines and the presence of MAP urolithiasis in canines, and to evaluate antimicrobial susceptibility patterns of bacteria isolated from canine uroliths. Methods: A total of 56 canines admitted for treatment with surgical removal of uroliths were recruited. Demographic characteristics and clinical chemistry data were recorded. Bacteria isolated from the removed uroliths were identified. Chemical compositions of the uroliths were analyzed by Fourier transform infrared spectrometer. Potential risk factors were determined with univariable and multivariable logistic regression analyses. Results: Of 56 canine urolithiasis, bacteria were isolated from uroliths of 38 canines (27 MAP and 11 non-MAP) but not from uroliths of 18 canines (5 MAP and 13 non-MAP). The most common bacteria found in nidus of MAP uroliths was Staphylococcus pseudintermedius (approximately 51%). An antimicrobial resistance was frequently found in Staphylococci isolates (42.86%). Multivariate logistic regression analysis showed that the predictors of MAP urolith in canine urolithiasis were being female (p = 0.044; adjusted odds ratio [OR], 10.22; 95% confidence interval [CI], 1.06-98.24) and the positive urolith culture (p = 0.012; adjusted OR, 8.60; 95% CI, 1.60-46.30). Conclusions: Our results indicate that S. pseudintermedius (a urease-producing bacterium) is the major causative bacteria of MAP uroliths. A positive urolith culture and being female are risk factors of MAP urolithiasis in canines.

• 한국임상수의학회지
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• 제21권2호
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• pp.205-208
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• 2004

A 9 year-old male Maltese with dysuria, pollakiuria, and stranguria was brought to the Veterinary Teaching Hospital, Chonnam National University. A right lateral abdominal radiograph was shown that 3 uroliths existed at the caudal aspect of the os penis and 5 uroliths existed in the passage of os penis. Uroliths were extracted by voiding urohydropropulsion and cystotomy in Maltese dog. The complication of cystotomy was hematuria, which might persist up to 2 days postoperatively but dysuria was not observed. So we applied voiding urohydropropulsion and cystotomy, and got a good prognosis. Gross examination of extracted uroliths were separated one from another but it was identified the same componet of calcium oxalate by stone quantitative analysis.

• 한국임상수의학회지
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• 제16권2호
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• pp.514-518
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• 1999

Portosystemic shunts in 3 Dogs with respiratory sign of cough and with dementia signs characterized by hypersensitivity, salivation, and seizure were diagnosed at veterinary teaching hospital of Seoul National University. In radiographs, microhepatica was observed. In abdominal ultrasonography, abnormal intrahepatic connections between the portal vein and the systemic vessels and tortuous vascularity were found. There was no complication such as ammonium urate urolith in kidney or urinary bladder, These dogs were treated with medicine and protein-restricted diet.

• 생약학회지
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• 제26권2호
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• pp.109-115
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• 1995

The plant of Pedicularis resupinata L. var. oppositifolia (Scrophulariaceae) appeared to be used for the treatment of rheumatoid arthritis, malignant abscess (tumor), urolith, and diuretics in oriental medicinal literatures. Three different compounds were isolated from the aerial part of the plant and characterized by the spectroscopic (UV, IR, NMR, MS) analysis. These compounds were acteoside (compound I), suavissmoside R1 (compound II), and ${_D}-mannitol$ (compound III).

• 생약학회지
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• 제24권3호
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• pp.258-262
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• 1993

The plant of Pedicularis resupinata var. oppositifolia(Scrophulariaceae) is described to be used for treatment of rheumatoid arthritis, malignant abscess (tumor), urolith and diuretics in oriental medicinal books. This study is concerned with some general pharmacological activities. It was observed that the methanol extract of the aerial part of this plant showed some effects on acute toxicity, carrageenin induced edema in rat paw, bile juice secretion and antibacterial effect. From this result it was obtained that the methanol extract revealed the antiinflammatory activity and bile juice secretion increasing effect. Thus, it was fractionated and buthanol fraction has obvious inhibition effect on edema and bile juice secretion increasing effect. The total extract showed low acute toxicity i.e., the minimum lethal dose was more than 8000mg/kg in oral administration in mice.

• 한국임상수의학회지
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• 제36권3호
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• pp.176-179
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• 2019

A giant prostatic urethral calculus has not been previously reported in dogs and should be distinguished from prostatic calculus. A 7-year-old castrated male Maltese dog with a 2-month history of relapsing hematuria and urinary incontinence with slowly progressing paraphimosis was referred. On abdominal radiography and ultrasonography, there was a giant calculus in the region of prostate or urethra, one left ureteral calculus, one urinary bladder calculus, and two penile urethral calculi. On computed tomography for evaluating the accurate location and planning the surgical approach, the giant calculus was located at the prostatic urethra. The calculi in urinary bladder, prostatic and penile urethra were surgically removed. These calculi were mixed-type of calcium oxalate monohydrate, struvite and calcium phosphate carbonate. On the basis of the urolith analysis and urine bacterial culture results, antibiotics and prescription diet were adjusted. At the 3-month follow-up, there were no clinical sings but paraphimosis was still remained, and ultrasonography revealed newly-formed, small urethral calculi at the prostatic urethra. This is the first report to describe the case of a canine giant prostatic urethral calculus and its clinical signs, diagnostic imaging findings, treatment, and outcome. CT may be useful to assess the accurate location and surgical approach for such calculi.

• 한국임상수의학회지
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• 제29권3호
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• pp.268-270
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• 2012

2개월령의 중성화하지 않은 암컷 말티즈가 급성의 혈뇨와 핍뇨를 주증으로 내원하였다. 환축은 복부 방사선 검사를 통해 방광 내 결석으로 진단되었다. 결석의 수술적 제거 후 미네소타 결석 센터로 의뢰하여 스트루바이트 결석을 확인하였다. 방광 내에는 3개의 스트루바이트 결석이 존재하였고 이로 인해 혈뇨가 생성되었다. 결석의 수술적 제거와 스트루바이트 결석의 생성에 대한 예방적 처방식 급여로 환축은 결석 제거 후 2달 동안 혈뇨와 같은 문제를 발생시키지 않았다.

• 한국임상수의학회지
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• 제27권4호
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• pp.453-456
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• 2010

생후 1개월령의 0.9 kg수컷 삽살개가 식욕부진, 배뇨곤란, 기립곤란, 침울을 주증으로 병원에 내원하였다. 신체검사에서는 빈맥, 저체온증, 점막창백 소견을 보였다. 혈액검사에서는 백혈구증가증과 빈혈소견이 있었고, 혈청생화학검사에서는 BUN (57.3 mg/dl)과 $NH_3$ ($584\;{\mu}g/dl$)의 증가, 알부민과 나트륨 및 칼륨의 저하소견을 보였다. 뇨검사에서는 혈뇨, 단백뇨, 당뇨, 세균뇨(Staphylococcus spp.)와 인산암모늄마그네슘결정뇨의 소견을 보였다. 방사선 검사에서는 확장된 방광과 요도내 2 mm크기의 결석을 발견할 수 있었다. 요도절개술로 요도내 결석을 제거하였고, 수술 후 환자는 정상적으로 회복되었다. 본 케이스는 요소분해효소 생산 세균의 감염과 고암모니아증을 동반한 어린 삽살개에서 스트루바이트 결석증 발생하였음을 보고한다.