• Childhood Kidney Diseases
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• 제27권2호
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• pp.127-132
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• 2023

Cystinuria, a genetically inherited disorder, is a rare cause of kidney stones. It is characterized by impaired transport of cystine and amino acids in the proximal renal tubule and the small intestine. Most patients develop cystine stones throughout their lifetime. Recurrent renal stones need to be extracted by repeated urologic interventions. Treatment options of cystinuria for preventing stone recurrence are limited and poorly tolerated. In this study, we report a pediatric case of cystinuria with a heterozygous SLC3A1 mutation diagnosed by stone analysis, measurement of urine cystine excretion, and genetic analysis. There were recurrent renal stones despite repetitive shock wave lithotripsy and retrograde intrarenal surgery. However, the rate of stone formation seemed to be slower after D-penicillamine was added into adequate hydration and urinary alkalinization.

• Korean Journal of Radiology
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• 제2권1호
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• pp.14-20
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• 2001

Objective: To compare the usefulness of unenhanced spiral CT (UCT) with that of excretory urography (EU) in patients with acute flank pain. Materials and Methods: Thirty patients presenting with acute flank pain underwent both UCT and EU. Both techniques were used to determine the presence, size, and location of urinary stone, and the presence or absence of secondary signs was also evaluated. The existence of ureteral stone was confirmed by its removal or spontaneous passage during follow-up. The absence of a stone was determined on the basis of the clinical and radiological evidence. Results: Twenty-one of the 30 patients had one or more ureteral stones and nine had no stone. CT depicted 22 of 23 calculi in the 21 patients with a stone, and no calculus in all nine without a stone. The sensitivity and specificity of UCT were 96% and 100%, respectively. EU disclosed 14 calculi in the 21 patients with a stone and no calculus in eight of the nine without a stone. UCT and EU demonstrated secondary signs of ureterolithiasis in 15 and 17 patients, respectively. Conclusion: For the evaluation of patients with acute flank pain, UCT is an excellent modality with high sensitivity and specificity. In near future it may replace EU.

• Korean Journal of Radiology
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• 제2권1호
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• pp.61-62
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• 2001

We present the characteristic plain radiographic and intravenous urographic (IVU) findings of calculus formed over a hair. A 66-year-old man who had been quadriplegic for 40 years because of vertebral injury was admitted for further evaluation of frequent urinary tract infection. Plain radiography showed a linear, serpiginous calcification in the lower abdomen, and IVU revealed a round filling defect with linear radiopacity in the bladder, suggesting calculus. The gross appearance of the stone after extraction demonstrated that calcification had formed over a hair.

• 한국임상수의학회지
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• 제15권2호
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• pp.331-338
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• 1998

This study evaluated the effect of acupuncture in dogs with experimentally induced spleens pancreas and urinary bladder disease. For the spleen studys sixteen dogs were divided into four groups(each of 4 in dogs): laserfonctnreg electroacupunctnre, acupuncture and control group. Spleen disease was brought by experimentally induced spleen traumata and then treatment was done once daisy for 4 days. The acupoints used were Pi-shu and Ge-shu. The effect of acupuncture was evaluated by clinical grmptomi hematological findings and blood chemical values. Acupuncture and Iaserpunctore group revealed rotatively fast recovery compared with other sloops. For the pancreas study, sixteen dogs were divided into four groups(each of 4 in dogs): laserpuncture, electroacupuncture, acupuncture and control group. Pancreas disease was brought by experimentally induced pancreas trauma, and then treatment was done once daily for 4 days The acupoints used were Wei-shu and Pi-shu. The effect of acupuncture was evaluate6 by clinical symptom, hematological findings and blood chemical values. Laserpuncture revealed relatively frost recovery and acupuncture group revealed secondly fast recovery after treatment. For the urinary bladder study, sixteen dogs were divided into four groups(each of 4 in dogs): laserpuncture, electroacupuncture,acupuncture and control group. Spleen disease was brought by experimentally induced urinary stoner and then treatment was done once daily for 4 days. The acupuncture used were Pang Guang-shu and Shen-shu. The effect of acupuncture was evaluated by clinical symptom, hematological findings, and blood chemical values. Laserpuncture and acupuncoure group revealed relatively fast recovery compared with other groups.

• 한국방사선학회논문지
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• 제4권1호
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• pp.11-17
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• 2010

요석은 고대 인류부터 지금 현재 인류까지 끊임없이 인간을 괴롭히고 있는 질병중의 하나이다. 하지만 딱히 예방법이 없어 문제가 생기면 비뇨기과적 치료가 절대적으로 필요한 질병이다. 이런 요석의 가장 큰문제점은 상당한 통증 과 구토, 발열등을 유발한다는 것이다. 통증은 요관을 통과 할 때나 요관이 요석으로 인한 심한 경련이 일어날 때 크게 일어난다. 이 통증은 마약성분이 강한 펜타닐 이나 페치딘 같은 강한 진통제에도 잘 잡히지 않는 경향이 있어 신속한 검사와 치료가 요구된다. 본 논문에서는 ESWL(Extracorpereal Shock Wave Lithotripsy)을 이용한 요석 치료시 특히 분쇄율은 낮고 환자의 통증은 심한 Proximal ureteral stone 과 Mid ureteral stone에 대해 각각의 여러 조건을 적용하여 최적의 치료방법과 최고의 분쇄율에 대하여 실험 과 연구를 하여 보았다. 실험결과 Proximal과 Mid ureter에 위치한 stone은 호흡에 의한 충격파의 적중률이 낮아 분쇄율이 distal ureter보다 낮았으나 방전interval을 줄임으로써 분쇄율을 높일 수 있었고, 낮은 방전 Power로 여러번 분쇄하는 것보다는 높은 방전 Power와 적절한 방전횟수로 분쇄를 하였을 때 ureter도 보호하면서 분쇄율이 높다는 것을 알 수 있었다.

• Journal of Yeungnam Medical Science
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• 제9권1호
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• pp.149-155
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• 1992

1983연 7월부터 1990년 6월까지 만 7년동안 비위축성 신절석술을 시행하였던 53명의 환자를 대상으로 수술후 합병증과 잔석의 빈도 등을 중심으로 임상적 관찰한 결과를 요약하면 다음과 같다. 가장 흔한 주소는 측복통으로 40례(72.7%)에서 나타났고, 다음은 혈뇨로 16례(29.1%)였고 증상 없이 우연히 발견된 경우는 4례(7.3%)였다. 동반질환은 타요로계 결석 질환이 16례(29.1%)로 가장 많았으며, 그외에 고혈압 11례(20.0%), 위궤양 7례(12.7%), 신낭종 5례(9.1%)등이었다. 수술전 요배양검사에서는 양성이었던 경우가 19례(34.5%)로 나타났으며, 그중 포도상구균이 5례로 가장 많았고, 그외에 대장균 3례, 녹농균 3례, Proteus 및 Acinebacter가 각각 2 등이었다. 신결석의 형태에 따른 분포는 다발성결석이 20례, 완전녹각석이 13례, 부분 녹각석(분지결석)이 10례, 신배결석이 9례, 신우결석이 3례이었다. 신결석의 성분분포는 수산칼슘과 인산칼슘의 혼합결석이 22례(40.0%)로 가장 많았고 다음은 수산칼슘석이 17례(30.1%), 인산마그네슘암모늄석이 8례(14.5%), 뇨산석이 3례(5.5%) 등이 순이었다. 평균수술 시간용 219.8분이었고 신혈관 차단시간용 평균 43.5분이었으며, 수술중 수혈은 22례(40.0%)였으며 수술당 평균수혈양은 2.36 pints이었다. 수술후 합병증은 지속적 요로감염 5례(9.1%), 무기폐 4례(7.3%), 일시적 뇨누출 2례(3.6%), 지연출혈 2례(3.6%) 및 요저류 2례(3.6%) 등이었고, 술후 3mm이상의 잔류결석은 15례(27.3%)였으나, 추적관찰중 8례(53.3%)에서 자연배출 되었고 결석의 재발은 2례(3.6%)에서 관찰되었다. 이상의 결과로 비위축성 신절석술은 결석조각을 모두 제거하고 누두성형을 시행하여 뇨정체를 없애줌으로써 결석재발의 빈도를 감소시키는데 좋은 방법이라고 사료된다.

• 대한약리학회지
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• 제16권2호
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• pp.77-83
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• 1980

The effectiveness of Cefoperazone in the treatment of urinary tract infection was evaluated in the Department of Urology, St. Mary's hospital from December 1. 1979 to April 30. 1980. In this studies, the cusative organisms were divided into 2 groups; 1) Single form. E. coli (8), Staphylococcus aureus(7), Proteus vulgaris (4), P. morganii(3), S. epidermis (1), Enterococcus(1), Klebsiella (2), N. gonococcus(1). 2) Mixed from: Proteus+E. coli(4), E. coli+other(1), Pseudomonas+Enterococcus(1), Klebsiella+other(1). Effectiveness on urological diseases. 1) Neurogenic bladder: Results were excellent in 3 cases, good in 4 cases and negative effect in 4 cases. 2) Non-gonococcal urethritis: In this group, the therapeutic results were favorable in 88.9% of all cases. (Excellent in 2, Fail in1) 3) Pyelonephritis: All(4 cases) were excellent. 4) Renal stone: Among the 4 cases of renal stone, only one case was responded to cefoperazone. 5) Two cases of urethral stricture, two cases of cystitis, one case of B.P.H. and one case of gonococcal urethritis were all excellent. No serious side effects were observed except slight dizziness in one case.

• 대한한의학방제학회지
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• 제26권4호
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• pp.341-362
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• 2018

Objective : This study's purpose was to review the clinical studies of Oryeong-San. Method : We searched papers about Oryeong-San using KISS, KTKP, PUBMED, Embase, Science Direct, and the key words "Goreisan", "Goreito", "Wu Ling San", "Oryeongsan", "Poria Five Powder" were used. Papers not matched with inclusion criteria were excluded. Results : Until today, there have been 133 studies on the effects of head diseases, urinary system diseases, edema, and other various effects of Oryeong-San. Of these, 23 studies were classified as clinical research papers. There were 8 cases of head diseases, 5 cases of urinary system diseases, 3 cases of edema, 2 cases of adjuvant, 1 case of Dysmenorrhea, 1 case of Primary Hypertension, 1 case of Primary Insomnia, 1 case of hydrocele, 1 case of side effects causing TINU syndrome. Conclusion : It can be seen that Oryeong-San has established the basis for application to the purpose of head disease(chronic subdural hematoma, hydrocephalus, hearing loss), urinary system disease(stone, urinary tract infection), edema, adjuvant, other hypertension and insomnia. On the other hand, considering one case that causes side effect of TINU syndrome, caution should be exercised when observing the progress of the patient taking the Oryeong-San.

• 대한간호학회지
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• 제27권4호
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• pp.943-952
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• 1997

This study was done to analyze the effects of prompted voiding therapy on urinary incontinence in elderly patients in an elderly care hospital. Specifically, this study looks to evaluate the effects of prompted voiding as an intervention for improving independent voiding and also identified the relationship of urinary continence to cognitive, emotional, and physical factors. The study was based on a pre-experimental design used to evaluate the effects of prompted voiding therapy on an experimental group without a control group. An experimental group of 143 patients was selected through convenience sampling from patients in an elderly care hospital. The data was collected from November 4 to December 14, 1996. Prompted voiding therapy is a behavioral therapy for managing incontinence and it is applied to patients who are cognitively impaired and dependent. In this study, the patients were asked at each designated time whether or not they had to urinate. If they answered yes, they were either given a bedpan or were assisted to the bathroom, and if the patient answered no, their diaper was checked to determine whether or not it was wet. The results were then recorded on the patients urinary voiding record. The urinary voiding score based on the model presented by Burton(1984), Burke and Walsh(1992), Chenitz, Stone & Salisbury(1991) was modified and used as a tool in this study. After forty six out of the total of 143 patients were selected for interviews through random sampling the levels of cognitive functions, mental depression and ADL(activities of dally life) within the given time frame were measured. In this study, the cognitive function was measured using the scale developed by Kabhn, Goldfarb, Pollack & Peck(1960), elderly mental depression, using the tool developed by Sheikh & Yesavage(1986), and the ADL(activities of dally living), through the Barthel Index. The data was analyzed through SPSS windows for descriptive statistics, repeated measured ANOVA and Pearson's correlation. According to the results of the study, the application of the prompted voiding therapy can improve the voiding pattern of patients. It was shown especially that incontinence could be controlled by the intervention developed according to the individual voiding pattern. In terms of the relationship between cognitive function, mental depression and ADL and the voiding function score, a close correlation was not found. It was shown that urinary incontinence can be improved through therapy even though patients have problems nth their cognitive, mental and physical functions.

• Advances in Traditional Medicine
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• 제9권3호
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• pp.259-267
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• 2009

Curcumin (CMN) is known to have beneficial role in anorexia, coryza, cough, diabetic wounds, and hepatic disorders apart from its inherent antioxidant effects. Therefore, the present study was aimed to evaluate antioxidant effect of CMN in prevention of nephrolithiasis in rats-induced by ethylene glycol (EG) and Vitamin D3 (Vit. D3). Male Wistar rats (175 - 200 g) were randomized in groups like control, EG + Vit. D3 induced nephrolithiatiatic rats, CMN treated rats, CMN + EG + Vit. D3 treated rats, Vit. E + EG + Vit. D3 treated rats. Urine was collected weekly throughout the experimental protocol and estimated for calcium oxalate (CaO) count. After completion of experimental protocol serum was estimated for blood urea nitrogen and creatinine. Both the kidneys were excised and used to evaluate levels of biomarkers of oxidative stress and calcium oxalate crystal deposition by histopathological studies. Administration of EG and Vit. D3 to rats resulted in increased oxidative stress, hyperoxaluria and renal deposition of CaO crystals. Supplementation with CMN improves kidney function, reduces elevated oxidative stress, urinary oxalate level and renal deposition of CaO which shows its protective action in nephrolithiasis. The increased deposition of stone in the kidney and stone forming constituents of nephrolithiatic rats were effectively lowered by treatment of CMN.