• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.6117-6121
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• 2015

Background: Most northeast Thai vegetables may play roles in human health by acting as antioxidant and anticancer agents. Recent study showed that Cratoxylum formosum subsp. pruniflorum (Kurz.) Gogel. (Teawdang) could inhibit growth of liver cancer cell lines. Cervical cancer, which has human papilloma virus as its main cause, is found at high incidence in Thailand. Due to increasing drug resistance, searches for potential anticancer compounds from natural source are required. Therefore, our purpose was to evaluate the cytotoxicity of Teawdang extracts in cervical cancer cell lines. Materials and Methods: Teawdang edible parts, purchased from Khon Kaen market during July-October 2013 was extracted with organic solvent. Phenolic profiles of crude hexane (CHE), ethyl acetate (CEE), methanol (CME) and water (CWE) extracts were performed by high performance liquid chromatographic (HPLC) techniques. Their cytotoxic effects on cervical cancer cells were investigated with HPV-non infected (C-33A) and HPV-infected (HeLa and SiHa) cell lines. Results: HPLC profiles showed that all crude extracts contained caffeine, ferulic acid and resveratrol. CME and CEE had high contents of gallic acid and quercetin. Catechin was found only in CWE. Cytotoxicity test showed that CEE had the lowest IC50 on HeLa ($143.18{\pm}13.35 {\mu}g/mL$) and SiHa cells ($106.45{\pm}15.73{\mu}g/mL$). C-33A cells were inhibited by CWE ($IC50=130.95{\pm}3.83{\mu}g/mL$). Conclusions: There were several phenolic compounds in Teawdang extracts which may have cytotoxic effects on cervical cancer cell lines. Investigation of these bioactive compounds as new sources of anticancer agents is recommended.

• Structural Engineering and Mechanics
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• v.14 no.5
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• pp.575-593
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• 2002

Based on the Mindlin plate theory, a refined discrete 15-DOF triangular laminated composite plate finite element RDTMLC with the re-constitution of the shear strain is proposed. For constituting the element displacement function, the exact displacement function of the Timoshenko's laminated composite beam as the displacement on the element boundary is used to derive the element displacements. The proposed element can be used for the analysis of both moderately thick and thin laminated composite plate, and the convergence for the very thin situation can be ensured theoretically. Numerical examples presented show that the present model indeed possesses the properties of higher accuracy for anisotropic laminated composite plates and is free of locking even for extremely thin laminated plates.

• Bulletin of the Korean Chemical Society
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• v.25 no.4
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• pp.460-465
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• 2004

Hydrofluoric acid has been used as a novel stripping agent for molybdenum(VI) after its extraction with Cyanex 301. In the extraction step, the effects of parameters such as type and initial concentration of acid, type of diluent, extractant concentration, metal concentration and temperature have been studied. In the stripping step, the effects of various stripping agents on stripping efficiency have been investigated. Hydrofluoric acid has been chosen as an effective stripping agent, and the effects of concentration of hydrofluoric acid, stripping time, volume of hydrofluoric acid and the number of stages of stripping have been studied. Molybdenum(VI) has been effectively separated from a large number of elements in binary mixtures, with a very high tolerance limit. Finally, the optimized method has been extended for the analysis of Mo(VI) in spent molybdenum catalysts.

• Ocean Systems Engineering
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• v.1 no.3
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• pp.195-205
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• 2011

A method for calibrating a laser profiling system for seafloor micro-topography measurements is described. The system consists of a digital camera and an arrangement of six red lasers that are mounted as a unit on a remotely operated vehicle (ROV). The lasers project as parallel planes onto the seafloor, creating profiles of the local topography that are interpreted from the digital camera image. The goal of the calibration was to determine the plane equations for the six lasers relative to the camera. This was accomplished in two stages. First, distortions in the digital image were corrected using an interpolation method based on a virtual pinhole camera model. Then, the laser planes were determined according to their intersections with a calibration target. The position and orientation of the target were obtained by a registration process. The selection of the target shape and size was found to be critical to a successful calibration at sea, due to the limitations in the manoeuvrability of the ROV.

• Corrosion Science and Technology
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• v.2 no.3
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• pp.127-134
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• 2003

In order to explain the effect of alloying Cu on the corrosion resistance of stainless steels in chloride media for both ferritic and austenitic stainless steels, the corrosion behavior of Cu-bearing stainless steels was investigated. Alloying Cu showed beneficial effect in an active potential range and harmful effect in a noble potential range. The beneficial effect of alloying Cu was explained by the stability of deposited Cu on an anodic surface. Difference in the effect of alloying Cu between the ferritic and austenitic steels was ascribed by the differences in their corrosion potentials and the morphology of the deposited Cu.

• Archives of Pharmacal Research
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• v.19 no.2
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• pp.122-125
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• 1996

We examined the effect of topical application of Shimotsu-to, a traditional Chinese herbal prescription, on carrageenin-induced edema in rats and ultraviolet radiation-induced erythema in guinea pigs. Shimotsu-to (5% in water) markedly suppressed an acute edema of rat hindpaw induced by 1% carrageenin, and was more effective than any other single crude drug componcent of Shimotsu-to, Topical treatment with this prescription also inhibited ultraviolet erythema on the back skin of guinea pigs (a human sunbrun model). These results suggest the therapeutic effect on acute inflammation by topical application of Shimotsu-to.

• Journal of Electrical Engineering and Technology
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• v.9 no.3
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• pp.1132-1136
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• 2014

In the context of increasing electric energy consumption in a data center, energy efficiency improvement is strongly emphasized. In a data center, electric energy is largely consumed by DC power supply system, which is based on a rectifier composed by multiple parallel converters. Therefore, rectifier efficiency must be improved for minimizing loss of DC power supply system. Rectifier efficiency can be modulated by load allocation to converters because converter efficiency depends on input AC power. In this paper, we propose a new control method to maximize rectifier efficiency. The method can control load allocation to converters by introducing active power converter control scheme and start-and-stop of converters. In order to illustrate optimal load allocations in a rectifier, a maximization problem of rectifier efficiency is formulated as a nonlinear optimization one. The problem is solved by Lagrangian relaxation method and the computation results provide the validity of proposed method.

• Korean Journal of Metals and Materials
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• v.50 no.2
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• pp.129-135
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• 2012

High speed casting technology is an attractive method to increase the productivity of continuous casting. However, high speed casting causes flow instability of molten steel in a mold. In this study, Large Eddy Simulation (LES) has been performed to identify the characteristics of mold flow for various shapes of submerged entry nozzles. The LES code has been newly developed to efficiently compute the two-phase flow by using the Fractional Step Method (FSM) combined with the Volume of Fluid (VOF) method. The Immersed Boundary Method was used to implement the shape of the submerged entry nozzle. Three cases of discharge angle of the submerged entry nozzle were computed and compared. The current results shed light on improving shape design of a submerged entry nozzle.

• Proceedings of the Safety Management and Science Conference
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• 2008.11a
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• pp.623-631
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• 2008

In this study, with the objects of 173 institutions of university and research institutions, investigation was carried out through visit investigation and questionnaire investigation. Frequency and strength of occurrences was acquired mainly through universities and research institutions which have reported occurrences of accidents to the Ministry of Education, Science, and Technology. Quantitative danger evaluation was conducted through frequency and strength of occurrences. Case study was carried out by selecting bio science laboratory of university and as the result of this study, degree of danger among the inspection objects of bio science laboratories, laboratory work place was evaluated as the most dangerous with the scores of 155.00 and as the result of average danger level, compression gas cylinder was evaluated as the most dangerous with the scores of 6.4000.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9511-9515
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• 2014

Cholangiocarcinoma (CCA) is a cancer of the bile duct epithelial cells. The highest incidence rate of CCA with a poor prognosis and poor response to chemotherapy is found in Southeast Asian countries, especially in northeastern Thailand and Lao PDR. Cathepsin B is a lysosomal cysteine protease which is regulated by cysteine proteinase inhibitors such as cystatin C. Elevation of cathepsin B levels in biological fluid has been observed in patients with inflammatory diseases and many cancers. We aimed to investigate the serum cathepsin B and cystatin C levels of CCA patients to evaluate the feasibility of using cathepsin B and cystatin C as markers for the diagnosis of CCA. Fifty-six sera from CCA patients, 17 with benign biliary diseases (BBD) and 13 from controls were collected and the cathepsin B and cystatin C levels were determined. In addition, cathepsin B expression was investigated immunohistochemically for 9 matched-pairs of cancerous and adjacent tissues of CCA patients. Serum cathepsin B, but not cystatin C, was significantly higher in CCA and BBD patient groups compared to that in the control group. Consistently, all cancerous tissues strongly expressed cathepsin B while adjacent tissues were negative in 7 out of 9 cases. In contrast, serum cystatin C levels were comparable between CCA and control groups, although serum cystatin C levels in the BBD group was higher than that in the control or CCA groups. When the serum cathepsin B to cystatin C ratio was calculated, that of the CCA group was significantly higher than that of the control group, and, although statistically not significant, the ratio of CCA group showed a trend to be higher than that of the BBD group. Thus, the cathepsin B to cystatin C ratio might be used as an alternative marker for aiding diagnosis of CCA.