• Title/Summary/Keyword: unifying principles

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Nuclear Bodies Built on Architectural Long Noncoding RNAs: Unifying Principles of Their Construction and Function

  • Chujo, Takeshi;Hirose, Tetsuro
    • Molecules and Cells
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    • v.40 no.12
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    • pp.889-896
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    • 2017
  • Nuclear bodies are subnuclear, spheroidal, and membraneless compartments that concentrate specific proteins and/or RNAs. They serve as sites of biogenesis, storage, and sequestration of specific RNAs, proteins, or ribonucleoprotein complexes. Recent studies reveal that a subset of nuclear bodies in various eukaryotic organisms is constructed using architectural long noncoding RNAs (arcRNAs). Here, we describe the unifying mechanistic principles of the construction and function of these bodies, especially focusing on liquid-liquid phase separation induced by architectural molecules that form multiple weakly adhesive interactions. We also discuss three possible advantages of using arcRNAs rather than architectural proteins to build the bodies: position-specificity, rapidity, and economy in sequestering nucleic acid-binding proteins. Moreover, we introduce two recently devised methods to discover novel arcRNA-constructed bodies; one that focuses on the RNase-sensitivity of these bodies, and another that focuses on "semi-extractability" of arcRNAs.

A Study on Standardization of Korean Cataloging Records : Focused on Rules for Cataloging (한국의 목록 표준화를 위한 방안 연구 -목록 관련 규칙을 중심으로-)

    • Journal of Korean Library and Information Science Society
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    • v.30 no.4
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    • pp.327-350
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    • 1999
  • This study tries to analyze the problems of rules for cataloging currently used n Korea such as KCR 3rd ed., KORMARC Description Rules, and KORMARC format, and to propose the methods solving the non-standardization of Korean cataloging records as follows: 1) No-main heading principles should be established so as to be applied to MARC format. 2) Description rules of cataloging currently used in Korea should be coordinated in accordance with MARC system and principles of bibliographical description. 3) Description rules of cataloging currently used in Korea should be coordinated in accordance with MARC system and principles of bibliographical description. 4) Unifying the format for CRT screen to display online catalog records are needed. 5) Conventional cataloging rules and MARC format should be coordinated.

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An interpretation of intelligence based on mathematical integration of elementary mechanisms in biology

  • Chauvet, Gilbert A.
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2003.09a
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    • pp.353-357
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    • 2003
  • Although it is more and more well accepted that modeling is a help for experimental biology, little is known about how to integrate physiological processes in general. The fact that no general theory exist in biology has big consequences, the most important being the difficulty to integrate biological phenomena. 1 will present a solution for the three dependent following issues: i) in an appropriate theoretical framework, integration consists in coupling models that each describe physiological mechanisms (formalization is a necessary condition to integration); ii) a biological theory with its own concepts leads to unifying principles in biology that are different from and complementary to physical principles; iii) such a formalized theory consists in a representation in terms of functional interactions and a specific formalism(S-Propagator). Hence a biological theory is of a topological and geometrical nature, in contrast to physical theories that are of a geometrical nature. An application to the interpretation of intelligence is proposed, based on the "intelligence"of movement.

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Finding the Way of Unifying the Theory and the Practice in Mathematics Education: Focused on Cobb's Research (수학교육연구의 이론과 현장의 실제사이의 간격 개선을 위한 방향탐색: Cobb 연구를 중심으로)

  • Lee, Chang Yeon;Joo, Hongyun;Choi-Koh, Sang Sook
    • School Mathematics
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    • v.16 no.4
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    • pp.709-726
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    • 2014
  • The purpose of the study was to pay attention to the studies of P. Cobb which have actively been quoted in the international research of mathematics education for the last three decades and to look at the result and effect of his research. In particular, we in-depth studied theories and the methods of the study which he has tried to reduce the gap in the theory and practice and investigated effects of his research to the Korean societies of mathematics education. Cobb made special effort to integrate radical constructivism and social constructivism and used emergent theory and symbolic interactionism as theoretical background of the study. Also he analyzed the mathematics classroom in individual and social perspectives based on the interpretive frames of social norm, sociomathematical norm and classroom-mathematical practices then dealt with equity and identity of the students. Because Cobb contributed significantly to the development of practical theory using design experiment as the method of studies, we presented the definition, characteristics, principles, processes and practices of the design experiment. We anticipate that his ways of research would be used as means of unifying the theory and the practice in school.

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Identity Formation and Self-Reflection Strategies in the Development of Apparel Design ePortfolios

  • Seifert, Christin;Chattaraman, Veena
    • Fashion, Industry and Education
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    • v.14 no.2
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    • pp.60-69
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    • 2016
  • Visual literacy, a key element of a design portfolio, is achieved by communicating a consistent visual aesthetic with respect to design elements, design principles and individual style. Yet, students often feel challenged in articulating their personal aesthetic or design philosophy in order to create a unifying design identity within a body of artifacts. This paper shares some best practices on overcoming this challenge through students' engagement in self-reflection and identity formation processes. The implemented innovative strategy in a senior-level portfolio development course for apparel designers involved four different phases: 1) one-on-one meetings to self-reflect on previous design work, 2) selection and revision of artifacts, 3) peer-review and critiques of revised portfolio artifacts, and 4) development of a final ePortfolio to showcase a unified design identity. It was evident that recording students' initial self-reflection in the form of a metacognitive oral report encouraged and motivated identity development in their portfolio. Further, students expressed their satisfaction in the ability to participate in the selection process of artifacts by self-reflecting about what they wanted to highlight about themselves and why. Overall, student outcomes from this strategy exceeded expectations and the portfolios developed were successful in creating a cohesive design identity.

A Comparison between BSCS's Guide and the Korean Curriculum for Developing Biological Literacy (생물학적 소양의 함양을 위한 BSCS 통합 권고안과 6,7차 교육과정 비교)

  • Koo, Soo-Jeong;Kim, Young-Shin;Kim, Byung-Suk;Lee, Sung-Jo;Chung, Wan-Ho
    • Journal of The Korean Association For Science Education
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    • v.20 no.3
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    • pp.396-410
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    • 2000
  • In this study, the concept presentation form, the content coherence of sub-dimensional concepts and the number of concepts of the 6th and the 7th Korean curriculum were analyzed comparing the guide to developing the secondary biology curricula to develop biological literacy with BSCS. According to the result, the discrimination between concept levels in the frame of contents of the Korean curricula is insufficient, because each of concepts presented in the knowledge domain as upper level and sub-dimensional concept elements as lower level are simply arrayed. Considering too much concepts of ecosystem, genetics, reproduction and metabolism, there should be an effort to reform the biological curriculum to include concepts evenly, not in the biased state, to reflect all the 6 unifying principles by BSCS for developing students' biological literacy. Finally there should be an effort to reflect the characteristics of each subjects concretely among Science 10, Biology I and Biology IT in the 7th curriculum considering the result that essential concepts to develop biological literacy are presented more in some principles of Biology II than Biology I. Thinking the results of the present study, concrete discussions should be made to set up the standard reference about biological literacy and to present essential concepts for teaching and learning to develop it in the process of biology textbook development for meeting the 7th Korean curriculum and in the development of 8th Korean curriculum in advance.

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New Trends in Private International Law and Our Response (국제상거래(國際商去來)의 사법통일(私法統一)노력과 우리의 대응(對應))

  • Park, Whon-Il
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.12
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    • pp.65-84
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    • 1999
  • During the past few decades, we have witnessed three approaches to overcome the legal disparities between trading countries: - determining the individual governing law in accordance with the conflict of laws principle; - unifying and harmonizing private international law into uniform rules and substantive laws under the auspices of ICC, UNCITRAL, UNIDROIT and various NGOs ; and - drafting model laws like the UNCITRAL Model Law on Electronic Commerce and promoting member countries to enact them. Against this backdrop, the United Nations Convention on Contracts for the International Sale of Goods (CISG) and the process by which it was adopted, established the benchmark for the unification of commercial law. The CISG, completed in 1980, merged civil and common law concepts and came into force in 1988 after a certain number of countries endorsed the treaty. Besides the CISG, the U.N. Limitations Convention and the UNIDROIT Principles of International Commercial Law, to name a few, have attempted to set cross-border legal norms and standards in the international business transactions. However, since the advent of computer-based commerce, there have emerged all-out efforts to establish uniform rules before national legal systems have been developed. As a consequence, the Model Law on Electronic Commerce has become a specimen legislation covering functional equivalents of paper-based writing and signature. For the credit enhancement exemplified by the Uniform Rules for Demand Guarantees (ICC Publication No.458), the UNCITRAL prepared the U.N. Convention on Independent Guarantees and Stand-by Letters of Credit, which was adopted by the U.N. General Assembly in 1995 but remains still not effective as only two countries have ratified this treaty so far. In this connection, two draft conventions underway at UNIDROIT and UNCITRAL deserve our attention as the probability of unification in the Korean Peninsula is mounting. They are to create security interests for commercial finance in moveable equipment and accounts receivable. The UCC-type security rights are regarded to be useful to enable the North Koreans with limited properties to borrow from the banks.

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The Tasks of Comparative Literary Studies and The Literary Transnationalism (비교문학의 과제와 문학적 트랜스내셔널리즘)

  • Lee, Changnam
    • Cross-Cultural Studies
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    • v.38
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    • pp.245-264
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    • 2015
  • In this paper, I suggest methodological ways of studying comparative literature regarding ongoing discussions of world and national literature. The role of comparative literature studies has widened in the contemporary era, in which nations have become rapidly entangled and the concept of the world as a unified entity is under question. In this regard, I critically review the traditional principles of the hospitality of cosmopolitanism and the exclusivity of the borders of national literatures. Further, I suggest that scholars adopt the concept by Sigmund Freud of "unfamiliar familiarity" as a methodological motive for studies of comparative literature. Based on this concept, scholars can further develop the unique methods of the discipline of comparative literary studies for teaching and research amidst the ongoing phenomenon of globalization. They can also use these methods to simultaneously contribute to solving the problem of "comparison without a unifying category of the world," as revealed by the results of deconstructional and postcolonial studies. Regarding community-based discussions of literature, I introduce the "bridge and door" metaphor, put forth by Georg Simmel, as a key concept in methodological consideration of translation and in comparative literary studies. In this paper, adopting the metaphor of the bridge and door as an intertextual and social model for comparative studies, I define the new role of comparative literary studies in literary transnationalism, which is particularly necessary when different languages and cultures overlap and become entangled. Regarding the rapidly changing contemporary world community, comparative literary studies, as an experimental discipline, is uniquely capable of examining this kind of community, which forms itself beyond and beneath individual nations.

Research on Safety Design of Residence Based on CPTED Strategy -focused on Gamcheon cultural village in Busan, Korea as an example- (CPTED 전략에 근거한 주거지역의 안전디자인에 관한 연구 -한국 부산 감천문화마을 사례를 중심으로-)

  • Zhang, Ning;Cho, Joung-Hyung
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.93-104
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    • 2021
  • In the process of the sustainable development of the world economy, the change and construction of urban living environment has always been the focus of people's attention. Therefore, the purpose of this study is to find out the potential safety hazards in residential areas, and put forward feasible improvement plans under the framework of CPTED theory.One is to collect the necessary literature. Secondly, according to the field investigation and questionnaire survey, sorting out the existing security risks. Finally, this paper puts forward the corresponding improvement and suggestion to this research. The conclusion is as follows: First, based on the six principles of CPTED theory, problems existing in Gamcheon Cultural Village, which is subject to research, were investigated. Second, six of the most serious safety issues (safety handle, landscaping, entrance control, signs, empty space, monitoring) were objectively analyzed, and designs were presented in terms of increasing safety stairs, installing automatic entrances, open access view, unifying signs, and building leisure areas.

A Study On Digital Hybrid System of Environment Design Based On Non-linear Feature (비선형성에 근거한 환경디자인의 디지털 하이브리드 체계에 관한 연구)

  • Kim, Yeon-Jung
    • Archives of design research
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    • v.18 no.4 s.62
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    • pp.185-194
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    • 2005
  • In the perspective of hybrid, design contains confused forms and styles. Thus, the question is what 'decisively affects' on life, happiness and peace of human beings: In the past scientific ecology that tries to solve the problem in the aspect of functional design was important. Now the question is beyond the scientific ecology because human has a different way of environmental adaptation from animals. From this point of view, design is defined as something beyond materialistic standard. Terry Eagleton said, 'Creative ability deviating oneself and transcending is the very standard to measure human beings' A tendency to hybridize one's own section off genre or pursuing dismantlement is found on such creative perspective. In other words, it focuses on making a space of human's cultural behavior by unifying creatively natural environment and architecture space in the organic aspect. Such phenomenon provides a new chance and possibility in environmental design through a new molding experiment according to the development of digital technology. As experiments of environment design using digital technology are actively implemented, ecological and cultural views hybridize to create a new cultural space of various functions and features. Such experiment in environment design highlights the connections of ecological view, recognition of value, and relation-centered ideas, and enables a tool pursuing a new cultural development. This study focuses on the paradigm of such digital hybrid design and purposes to set the system by analyzing the application styles and principles of environment design through theoretical and case studies. In addition, it promotes a new possibility to develop environment design in the history of civilization.

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