• Title/Summary/Keyword: understanding levels

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Eosinophilic Esophagitis and Eosinophilic Gastroenteritis: Similarities and Differences

  • Yoshikazu Kinoshita;Norihisa Ishimura;Shunji Ishihara
    • Journal of Digestive Cancer Research
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    • v.6 no.1
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    • pp.1-5
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    • 2018
  • Eosinophilic gastrointestinal disease (EGID), a chronic allergic condition characterized by dense infiltration of eosinophils in the digestive tract, is classified into two types, eosinophilic esophagitis (EoE), which features dense infiltration of eosinophils in the esophageal epithelial layer, and eosinophilic gastroenteritis (EGE), in which the entire digestive tract including the esophagus may be involved. Patients with EoE only have esophageal symptoms, since the other parts of the digestive tract are not involved. On the other hand, 80% of EGE patients have lesions in the small intestine. The esophageal epithelial layer in healthy individuals has no or negligible infiltration by eosinophils, while the small intestinal mucosal layer, especially the distal small intestinal mucosa, can show dense eosinophil infiltration even in the absence of disease. Therefore, histological changes observed in cases of EGE are not qualitative but rather quantitative, as compared to EoE, which has qualitative histopathological changes, indicating important pathogenetic differences between the types. Comparisons of clinical, laboratory, and morphological characteristics between EoE and EGE have revealed several interesting differences. Both EoE and EGE patients are frequently affected by atopic diseases, such as bronchial asthma and allergic rhinitis, and elevated plasma levels of Th2 type cytokines and chemokines are also similarly seen in both. On the other hand, age at diagnosis differs, as the former is generally found in individuals from 30 to 50 years old, while the latter appears in all age groups. Additionally, 80% of patients with EoE are male as compared to only 50% of those with EGE. Furthermore, approximately 60% of patients with EoE respond favorably to proton pump inhibitor (PPI) administration, whereas EGE patients rarely show a response to PPIs. Nevertheless, both diseases show a similarly favorable response to a six foods elimination diet and glucocorticoid administration. These similarities and differences of EoE and EGE provide important clues for understanding the pathogenesis of these EGID types.

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The Effect of Driving Specific Characteristics and Life Stress on Traffic Fafety (운전 상황에서의 개인특성과 생활스트레스가 교통안전에 미치는 영향)

  • Suran Lee ;EunKyoung Chung ;JaeYoung Kwon ;Young Woo Sohn
    • Korean Journal of Culture and Social Issue
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    • v.17 no.3
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    • pp.305-320
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    • 2011
  • The objectives of the present research are twofold. First, this research aims to compare the effect of trait characteristics(sensation seeking, social resistance and type-A behavior) with that of driving specific characteristics(driving anger and type-A driving) on problematic driving behavior. Second, the role of life stress as a mediator in the relationships between general trait characteristics and traffic safety index was examined. 1158 licensed commercial vehicle drivers were surveyed and their accident-related records were obtained in this research. Results showed that driving specific characteristics were significant indicators of traffic safety and life stress mediated the relationships between general trait characteristics and traffic safety index. These findings implicate that understanding drivers' driving specific characteristics and their levels of life stress is important to reduce problematic driving behaviors and enhance traffic safety.

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The Moderating Effect of Peer Attachment on the Relationship between School Violence Victimization and Cyber Violence Victimization in Children (아동의 학교폭력 피해경험이 사이버폭력 피해경험에 미치는 영향에서 또래애착의 조절효과 검증)

  • Sang woo Kim;So ra Lim
    • Journal of Korean Physical Therapy Science
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    • v.30 no.3
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    • pp.91-104
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    • 2023
  • Background: The purpose of this study is to investigate whether peer attachment serves as a positive emotional resource for children who have experienced school violence and cyber violence victimization. In addition, we aim to present alternative programs to reduce school violence and promote positive peer attachment among children. Design: We utilized data from the 13th year(2020) of the Panel Study on Korean Children for this study. Methods: The survey was conducted through a questionnaire administered by surveyors, and the total number of cases was 1,357. Results: First, the effects of school violence and cyber violence victimization experiences were confirmed. Second, it can be inferred that children with isolation in peer relationships may ultimately be more vulnerable to cyber violence victimization, as their interactions in cyberspace may also be undermined, highlighting the potential impact of social relationships on cyber violence victimization. Third, it can be observed that children with high levels of peer attachment are emotionally stable, even when exposed to school violence and cyberviolence victimization, which may enable them to regulate the degree of victimization they experience. Conclusion: School violence experience and cyber violence experience interact with each other, and in this relationship, positive peer attachment is a positive resource. Therefore, it emphasizes the importance of the relationship between friends in preventing and overcoming school violence and provides suggestions for solutions based on this understanding.

A Study on Predicting the Potential for Bid-Rigging among Bidders using FTT in Public Construction Projects (FTT를 활용한 입찰실무자의 입찰담합 가능성 예측 연구)

  • Cho, Jin-Ho;Shin, Young-Su;Kim, Byung-Soo
    • Korean Journal of Construction Engineering and Management
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    • v.24 no.6
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    • pp.36-44
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    • 2023
  • The aim of this study is to predict the potential for bid-rigging among public construction bidders and develop preventive and responsive measures. By employing the Fraud Triangle Theory (FTT), which considers the factors of opportunity, pressure, and rationalization, we analyze and explore the bid-rigging potential among construction industry professionals. A survey is conducted among General and specialized construction firms to validate the FTT research model and predict individual bid-rigging tendencies. The results indicate that higher levels of pressure, greater opportunities, and stronger rationalization increase the likelihood of individual bid-rigging. Moreover, more opportunities and stronger rationalization also raise the potential for bid-rigging by others. Understanding these dynamics enhances our knowledge and contributes to the development of policies aimed at preventing bid-rigging.

Exploring Service Strategies for Academic Libraries Utilizing Fourth Industrial Revolution Technologies (대학도서관을 위한 4차 산업혁명 기술 활용 서비스 전략 탐색 연구)

  • Hyun Soo Chae;Yewon Kim;Hyeyoung Kim;Jee Yeon Lee
    • Journal of the Korean Society for information Management
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    • v.40 no.4
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    • pp.95-121
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    • 2023
  • This study aims to explore the combinations of services and technologies for academic libraries to use based on librarians' perception and establish effective service strategies accordingly. The literature review facilitated an understanding of Fourth Industrial Revolution technologies impacting the libraries. We discovered how technologies are transforming library services. We analyzed the academic library services to categorize their service structure. The survey revealed the necessity of introducing technology for each service category and the appropriate automation levels of services based on the perception of librarians. The survey results identified nine prioritized combinations of academic library services and technologies. Based on the analysis, we proposed the service-technology strategies for each category. This study has significance in exploring the potential for introducing and utilizing new technologies to enhance academic library services and exploring ways to combine services and technologies based on the common opinion of librarians.

Analysis of Minimum Airflow Differences between Supply and Exhaust Air according to Airtightness of Rapidly Converted Temporary Negative Pressure Isolation Rooms (긴급전환형 임시음압격리병실의 기밀도에 따른 최소 급배기 유량차 평가)

  • Shin, Hee Won;Kim, Dong Wook;Kim, Ji Min;Jung, Hyo Beom;Kang, Dong Hwa
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.29 no.4
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    • pp.69-77
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    • 2023
  • Purpose: During the COVID-19 pandemic, there have been many cases of converting regular hospital wards into temporary negative pressure isolation wards. The purpose of this study is to evaluate the minimum airflow differences that satisfies the pressure difference criteria(-2.5 Pa) according to airtightness of switching type wards, in preparation for utilization of aging regular wards as negative pressure isolation wards. Methods: Visual inspection and field measurements were conducted using blower door to evaluate airtightness of 5 hospital wards. CONTAM simulation was used to assess the airflow differences when pressure difference between the corridor and wards met the criteria at various levels of airtightness. Results: The ACH50 of evaluated wards ranged from 19.3 to 50.1 h-1 with an average of 37.0 h-1, indicating more than four times leakier than other building types. The minimum airflow differences increased as the airtightness of the wards decreased and the size of the wards increased. Implications: When operating rapidly converted negative pressure isolation wards, understanding airtightness is crucial for determining the minimum airflow differences to maintain the pressure differences. The analysis of this study suggests that improving the airtightness of aging rooms is essential and the minimum airflow differences should be suggested considering both the airtightness and size of rooms.

Acute Exposure to Karenia mikimotoi Induces Oxidative Stress and Reduces Immune Parameters in the Marine Medaka Oryzias javanicus

  • Seong Duk Do;Yun Kyung Shin;Jae-Sung Rhee
    • Journal of Marine Life Science
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    • v.8 no.2
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    • pp.190-195
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    • 2023
  • In this research, the marine medaka Oryzias javanicus underwent a 96 h exposure to two concentrations of the red tide dinoflagellate Karenia mikimotoi (1,000 and 5,000 cells mL-1), and the temporal variations in biochemical responses related to antioxidant and immunity parameters were assessed in the liver tissue. The study revealed a significant increase in ichthyotoxicity with elevated cell concentrations of K. mikimotoi, especially evident at 96 h in marine medaka exposed to 5,000 cells mL-1. At 1,000 cells mL-1 of K. mikimotoi, the opercular respiratory rate showed a significant increase, whereas exposure to 5,000 cells mL-1 resulted in a lowered rate. The intracellular malondialdehyde content was significantly elevated in response to both cell concentrations at 96 h. Regarding glutathione content, levels were significantly increased by exposure to both cell concentrations. Catalase and superoxide dismutase enzymatic activities experienced an increase at 1,000 cells mL-1 of K. mikimotoi, while their activities were reduced at 5,000 cells mL-1 at 96 h. The analysis of two immunity parameters, alternative complement pathway and lysozyme, demonstrated significantly reduced activities in the liver tissue exposed to 5,000 cells mL-1 of K. mikimotoi. These findings aim to enhance the understanding of K. mikimotoi toxicity in marine fish by offering insights into biochemical responses associated with harmful algal blooms.

Evaluation Model Platform based on Mature to improve IS audit quality (IS 감리 품질 향상을 위한 성숙도 기반의 평가 모델 플랫폼)

  • Jong-Seok Lee;Young-Gon Kim
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.23 no.6
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    • pp.9-14
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    • 2023
  • The purpose of information system audit is to proactively identify and efficiently manage all risk factors that may arise during the process of constructing an information system, in order to assist in achieving the objectives of information system development. However, there is currently significant dissatisfaction with the quality and effectiveness of the auditing process, leading to ongoing research aimed at finding effective solutions. In this paper, we propose a multi-level evaluation model to enhance mutual understanding between auditors and evaluators and present a model that undergoes a maturity process, improving its levels and stages. We introduce a maturity-based evaluation model platform, enabling efficient communication between auditors and evaluators, allowing for real-time feedback, and supplementing it through continuous search. By presenting this multi-level model aimed at maturing the entire system, we aim to efficiently manage the system development process.

Optimisation of Infrastructure within the Melbourne Urban plan

  • Koorosh Gharehbaghi;Vincent Raso
    • International conference on construction engineering and project management
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    • 2011.02a
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    • pp.299-303
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    • 2011
  • Congestion is a growing concern of many global cities and the demands on Infrastructure services within a locale coupled by the rising expectations from the growing population places stress on these cities. This entails the ability to build a sustainable community that requires an understanding and recognition of Population growth, changing demographics and the ever changing urban development on both a macro and micro level. Infrastructure is an integral part of Australian economy, particularly the 'Infrastructure Assets Management' which highlights the importance towards the development of sustainable communities for Melbourne's future. Melbourne 2030 is a comprehensive representation of government's response to a wide-ranging population growth within Melbourne metropolitan and surrounding areas. Urban plan and specific Infrastructure Assets Planning needs not only to provide sufficient Infrastructure to a community, but it must also be efficient and innovative so that it produces an optimised management system. A system that incorporates engineering techniques that will be sustainable for decades to come by maintaining an acceptable level of services to its intended community in an effective manner, which also strengthens service delivery. The fundamental challenges for optimization of Infrastructure with the Melbourne urban plan is, the ability to manage and sustain maintenance of Infrastructure to provide the acceptable level of service required by the community in a most effective manner which also strengthens service delivery to contribute towards Melbourne 2030. This paper particularly investigates some of the fundamental issues within the Melbourne urban plan such as Infrastructure Asset Management, AusLink and the Australian Road Management Act 2004, which the Governments at all levels must deal with to provide an economically viable solution to the changing Infrastructure so it may suits the needs and services the strategies of a metropolis.

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Analysis of Artificial Intelligence Mathematics Textbooks: Vectors and Matrices (<인공지능 수학> 교과서의 행렬과 벡터 내용 분석)

  • Lee, Youngmi;Han, Chaereen;Lim, Woong
    • Communications of Mathematical Education
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    • v.37 no.3
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    • pp.443-465
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    • 2023
  • This study examines the content of vectors and matrices in Artificial Intelligence Mathematics textbooks (AIMTs) from the 2015 revised mathematics curriculum. We analyzed the implementation of foundational mathematical concepts, specifically definitions and related sub-concepts of vectors and matrices, in these textbooks, given their importance for understanding AI. The findings reveal significant variations in the presentation of vector-related concepts, definitions, sub-concepts, and levels of contextual information and descriptions such as vector size, distance between vectors, and mathematical interpretation. While there are few discrepancies in the presentation of fundamental matrix concepts, differences emerge in the subtypes of matrices used and the matrix operations applied in image data processing across textbooks. There is also variation in how textbooks emphasize the interconnectedness of mathematics for explaining vector-related concepts versus the textbooks place more emphasis on AI-related knowledge than on mathematical concepts and principles. The implications for future curriculum development and textbook design are discussed, providing insights into improving AI mathematics education.