• 대한한의학회지
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• 제40권4호
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• pp.61-71
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• 2019

Objectives: The purpose of this study is to determine the effect of Yuhyangjeongtong-san on the recovery of tibial fractures in rats. Methods: In this study, osteocalcin and Calcitonin, CTX-2, TGF-β and BMP-2, which are used as indicators of bone formation, were analyzed after hematologic fractures using experimental rats. In addition, the fracture union process was confirmed using X-rays. Results: Osteocalcin, Calcitonin and BMP-2 showed a significant increase compared with the control at 4 weeks. CTX-2 and TGF-β showed a significant increase compared with the control at 3 weeks. On X-ray, YJS treated group, as the experiment progressed, the boundary line became blurred, the bone outline was clearly visible, and the fracture recover was progressing. Conclusion: The findings suggest that YJS can play a significant role in the repair of fractures. Therefore YJS is likely to be used to treat fractures.

• 한국조경학회지
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• 제25권3호
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• pp.143-154
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• 1997

The fundamental concept of shared street is integration of traffic and pedestrian activity as a positive principle for street planning. Shared streets have been very successful in several countries in terms of reductions in traffic accidents, increased social interaction and children's play, and a high degree of satisfaction by the residents. This paper proposes the concept of shared street to solve traffic problem without reorganizing traditional street structure and without disturbing traditional function of street as a living space for residents. And this study examines detail concepts and techniques of the shared street and applies them to a pedestrian oriented streetscape design of "Ducksugung-Gil," Seoul, which was one of the most important streets in Korean modernization history.n history.

• 대한한방내과학회지
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• 제36권2호
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• pp.200-206
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• 2015

Objectives: The purpose of this study is to report the possibility of treatment of locally advanced non-small cell lung cancer with Traditional Korean Medicine based allergen-removed Rhus verniciflua Stokes (ARVS) following chemoradiotherapy. Methods: A patient with locally advanced non-small cell lung cancer (stage IIIB) felt chest discomfort, fatigue, and anxiety after chemoradiotherapy. To prevent recurrence, he opted to receive Traditional Korean Medicine. Results: After treatment with ARVS, the size of the residual primary cancer and a metastatic lymph node decreased, without new cancerous regions. The patient has maintained good performance and has shown prolonged overall survival. Conclusions: This report suggests that ARVS may play a therapeutic role in the treatment of locally advanced non-small cell lung cancer after chemoradiotherapy. Further studies will be needed to determine the effect of ARVS on locally-advanced unresectable non-small cell lung cancer.

• 대한화장품학회지
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• 제17권1호
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• pp.39-47
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• 1991

Dental caries has been reported to be infectious disease by Streptococcus mutans(S. mutans). The ability of S. mutans to produce dental plaque has been shown to be related to glucan synthesis from sucrose by glucosyltransferase (GTase). Glucan is known to play an important role in the initiation of smooth surface caries. For preventing dental caries by traditional medicines, two hundred kinds of natural products were assayed for inhibiting activity against S. mutans and GTase. During the assay course, we chose some active plants against S. mutans and GTase and then applied these plant extracts to toothpaste.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2001년도 추계 학술대회논문집
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• pp.182-189
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• 2001

A project has been initiated at KISTI Supercomputing Center at year 1999 to build a Tflops cluster in order to support newly emerging demands for larger scale parallel computing resources. As a supportive substitute of traditional supercompters, the cluster systems are expected to play important role in supporting diversified computational needs. In this paper, KISTI Supercomputing Center's working status of building Tflops cluster system and future plans.

• 산업경영시스템학회지
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• 제22권52호
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• pp.141-153
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• 1999

The focus of marketing study on the strategic tools has shifted from traditional 4Ps'(product, price, place and promotion) to macro relationship marketing which places emphasis on interfirm relationships. The purpose of this study is to develope antecedent variables of relationship type which play the most important role of interfirm relationships, and the antecedent variables of relationship structure comprises three factors : 1) transactional relationship structure, 2) hierarchical relationship structure and 3) embedded relationship structure.

• 지역과문화
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• 제7권3호
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• pp.23-48
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• 2020

이 글의 목적은 현재 '관객을 위한 하나의 놀이 극'으로서 의미가 큰 하회별신굿탈놀이의 고착된 연희를 확장하기 위해 초랭이 캐릭터의 정체성 전환을 통하여 연희의 확장 가능성을 고찰하는 것이다. 초랭이는 잠재적 변혁의식의 소유자, 민중의 소극적 대변자, 관객에게 지배계층에 대한 조롱을 암묵적으로 승인받는 인물이다. 초랭이를 통해 관객은 통쾌함을 느끼지만 동시에 한계도 절감한다. 이에 영리하지만 신분의 한계를 뛰어넘지 못하는 초랭이를 정체성 전환 이론의 '역전'과 '전치'를 적용해 변혁의식을 품은 인물로 성격을 전환하였다. 또한 매체전환 스토리텔링 이론의 '확장' 방식으로 관객의 욕구와 시대정신에 부합하는 새로운 '초랭이마당'을 기획하였다. 초랭이마당은 '양반선비마당' 다음에 덧붙는 신규 마당으로 하회탈놀이의 대사 기능과 구현의 원리를 적용해 창작하였으며 이를 대본으로 제시했다. 초랭이마당은 애매한 화해로 마무리되는 현재의 양반선비마당의 결말을 오늘날의 관객도 수긍할 수 있는 완결적 방식으로 구조화할 수 있다. 이 글은 전통의 새로운 창조라는 맥락에서 전통공연예술의 변형을 시도한 실험적 연구라는 의의가 있다. 하회마을이 세계문화유산으로 지정되어 외부방문객의 상설공연 관람이 더욱 증대될 전망이다. 현행 하회별신굿탈놀이는 시대의 구성물이지만 변화를 지속하였기에 지금까지 존속될 수 있었다. 전통공연예술은 보존과 전승도 중요하지만 시대정신과 흐름에 맞추어 미래를 향해 나아가는 여시구진(與時俱進)의 자세도 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.499-503
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• 2012

The present study was based on the unexpected discovery that norcantharidin exerted anti-angiogenesis activity when effects on growth of human colon cancer were studied. The aim was to further verify this finding and explore possible mechanisms using a tumor xenograft model in nude mice. We confirmed that norcantharidin (5 or 15 mg/kg) could inhibit angiogenesis of human colon cancer in vivo. In vitro, crossing river assay, cell adhesion assay and tube formation assay indicated that NCTD could reduce the migration, adhesion and vascular network tube formation ability of HUVECs. At the same time, the expression levels of VEGF and VEGFR-2 proteins which play important roles in angiogenesis were reduced as examined by western blotting analysis. Taken together, the results firstly showed NCTD could inhibit angiogenesis of human colon cancer in vivo, probably associated with effects on migration, adhesion and vascular network tube formation of HUVECs and expression levels of VEGF and VEGFR-2 proteins.

• 보존과학회지
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• 제35권4호
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• pp.363-372
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• 2019

Animal glue has been used as a binder in Dancheong since the Joseon dynasty. Binders play an important role in determining the physical characteristics of a painting layer. The analysis of binders can be used to identify the materials and techniques used in traditional Dancheong. Binders can be investigated using physicochemical component analyses methods such as gas chromatography/mass spectrometry, pyrolysis-gas chromatography/mass spectrometry, and fourier transform infrared spectroscopy, but the detection characteristics vary depending on the degradation properties of the pigment and binder. Therefore, cross-validation using a combination of physicochemical analysis and enzyme immunoassay is used to increase the reliability of the results. In this study, we present an enzyme-linked immunosorbent assay (ELISA) as an example of an enzyme immunoassay as a method for analyzing animal glue, a traditional binder used in Korea. The applicability of ELISA was tested using commercial animal glue, in addition to animal glue produced using a variety of extraction conditions. The animal glue was analyzed in a Noerok-additionally coated-replica sample to evaluate the possibility of analyzing the animal glue in a paint layer mixed with pigment. Based on the results, we performed an assay on the use of animal glue in the Dancheong sample of the temples of the Joseon dynasty, that are estimated to have been built in the 17^th century.

• 생약학회지
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• 제42권1호
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• pp.46-53
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• 2011

Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 66 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 31 herbal medicines ($IC_{50}$ < $50\;{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, 5 herbal medicines, Camptotheca acuminata (branches and leaves), Quercus franchetii (branches), Camellia pitardii (leaves, branches, and fruits), Antidesma bunius (whole plants), and Loranthus parasiticus (whole plants) showed more potent inhibitory activity (approximately 6-20 fold) than the positive control aminoguanidine ($IC_{50}=52.96\;{\mu}g/ml$).