• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.7
• /
• pp.3431-3436
• /
• 2012

Objective: X-ray cross-complementing group 4 (XRCC4) is a major repair gene for DNA double-strand breaks (DSB) in the non-homologous end-joining (NHEJ) pathway. Several potentially functional polymorphisms of the XRCC4 gene have been implicated in breast cancer risk, but individually published studies showed inconclusive results. The aim of this meta-analysis was to investigate the association between XRCC4 polymorphisms and the risk of breast cancer. Methods: The MEDLINE, EMBASE, Web of science and CBM databases were searched for all relevant articles published up to June 20, 2012. Potential associations were assessed with comparisons of the total mutation rate (TMR), complete mutation rate (CMR) and partial mutation rate (PMR) in cases and controls. Statistical analyses were performed using RevMan 5.1.6 and STATA 12.0 software. Results: Five studies were included with a total of 5,165 breast cancer cases and 4,839 healthy controls. Meta-analysis results showed that mutations of rs2075686 (C>T) and rs6869366 (G>T) in the XRCC4 gene were associated with increased risk of breast cancer, while rs2075685 (G>T) and rs10057194 (A>G) might decrease the risk of breast cancer. However, rs1805377 (A>G), rs1056503 (G>T), rs28360317 (ins>del) and rs3734091 (A>G) polymorphisms of XRCC4 gene did not appear to have an influence on breast cancer susceptibility. Conclusion: Results from the current meta-analysis suggest that the rs2075685 (G>T) and rs6869366 (G>T) polymorphisms of the XRCC4 gene might increase the risk of breast cancer, whereas rs2075685 (G>T) and rs10057194 (A>G) might be protective factors.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.sup3
• /
• pp.59-64
• /
• 2016

Breast cancer (BC) is the most common cancer in females (27% of the total) and the main cause of death (16%) due to cancer in women in developed and developing countries. Variations in its incidence rate among geographical areas are due to various contributing factors. Since there have been a lack of studies on this topic in our country, the present spatial analysis of breast cancer incidence in Iran in 2009 was conducted using data from the national cancer registry system. The reported incidences of the disease were standardized according to the World Health Organization population and the direct method. Then data was inserted into the GIS software and finally, using the Hot Spot Analysis (Geties-Ord Gi), high-risk areas were drawn. Provinces with incidences 1.96 SD higher or lower than the national average were considered as hot spots or cold spots, at the significance level of 0.05%. In 2009, a total of 7,582 cases of BC occurred in Iran. The annual incidence was 33.2 per hundred thousand people. Our study showed that the highest incidence of BC in women occurred in the central provinces of the country, Tehran, Isfahan, Yazd, Markazi and Fars. The results of hot spots analysis showed that the distribution of high-risk BC was focused in central parts of Iran, especially Isfahan province (p <0.01). The other provinces were not significantly different from the national average. The higher incidence in central provinces may be due to greater exposure to carcinogens in urban areas, a Western lifestyle and high prevalence of other risk factors. Further epidemiological studies about the etiology and early detection of BC are essential.

• Journal of Broadcast Engineering
• /
• v.13 no.3
• /
• pp.328-338
• /
• 2008

Multi-view video coding (MVC) based on H.264/AVC encodes multiple views efficiently by using a prediction scheme that exploits inter-view correlation among multiple views. However, with the increase of the number of views and use of inter-view prediction among views, total encoding time will be increased in multiview video coding. In this paper, we propose a fast mode decision using both MB(Macroblock)-based region segmentation information corresponding to each view in multiple views and global disparity vector among views in order to reduce encoding time. The proposed method achieves on average 40% reduction of total encoding time with the objective video quality degradation of about 0.04 dB peak signal-to-noise ratio (PSNR) by using joint multi-view video model (JMVM) 4.0 that is the reference software of the multiview video coding standard.

• Restorative Dentistry and Endodontics
• /
• v.45 no.1
• /
• pp.1.1-1.9
• /
• 2020

Objectives: The purpose of this study was to determine the incidence of radix molaris (RM) (entomolaris and paramolaris) in the mandibular first permanent molars of a sample Saudi Arabian subpopulation using cone-beam computed tomography (CBCT). Materials and Methods: A total of 884 CBCT images of 427 male and 457 female Saudi citizens (age 16 to 70 years) were collected from the radiology department archives of 4 dental centers. A total of 450 CBCT images of 741 mature mandibular first molars that met the inclusion criteria were reviewed. The images were viewed at high resolution by 3 examiners and were analyzed with Planmeca Romexis software (version 5.2). Results: Thirty-three (4.5%) mandibular first permanent molars had RM, mostly on the distal side. The incidence of radix entomolaris (EM) was 4.3%, while that of radix paramolaris was 0.3%. The RM roots had one canal and occurred more unilaterally. No significant difference in root configuration was found between males and females (p > 0.05). Types I and III EM root canal configurations were most common, while type B was the only RP configuration observed. Conclusions: The incidence of RM in the mandibular first molars of this Saudi subpopulation was 4.5%. Identification of the supernumerary root can avoid missing the canal associated with the root during root canal treatment.

• Journal of the Institute of Convergence Signal Processing
• /
• v.11 no.1
• /
• pp.13-18
• /
• 2010

Most of the research in the multi-touch area is based on the FTIR(Frustrated Total Internal Re리ection), which is just implemented by using the previous approach. Moreover, there are not the software solutions to improve a performance in the multi touch-blobs detection or the user gesture recognition. Therefore, we implement a multi-touch table-top display that is based on the DI(Diffused Illumination), the improved touch-points detection and user gesture recognition. The proposed method supports a simultaneous transformation multi-touch command for objects in the running application. Also, the system latency time is reduced by the proposed ore-testing method in the multi touch-blobs detection processing. Implemented device is simulated by programming the Flash AS3 application in the TUIO(Tangible User Interface Object) environment that is based on the OSC(Open Sound Control) protocol. As a result, Our system shows the 37% system latency reduction, and is successful in the multi-touch gestures recognition.

• Korean Journal of Community Nutrition
• /
• v.21 no.6
• /
• pp.558-573
• /
• 2016

Objectives: The purpose of this study was to evaluate the main sources of dietary sodium and potassium intake in Koreans by gender, age and regions. Methods: We used the data from 2010-2012 KNHANES. A total of 20,387 subjects aged 8 years and older were included. Intakes were compared by gender, age (8-18, 19-49 and >50 years) and geographical regions in Korea. Dishes were classified into 28 dish groups based on cooking methods. Statistical analysis was performed by using the SAS 9.3 and SUDAAN 11.0.1 software. Results: The mean sodium intake of Koreans was $4866.5{\pm}35.9mg/day$, which was 2.4 times higher than the adequate intake (AI) of sodium for Koreans. We found that daily sodium intakes were significantly different by age, gender and regions. Men and aged over 50 years had significantly higher sodium intake than women and other age groups. The mean potassium intake in Koreans was $3002.2{\pm}19.4mg/day$ and daily potassium intakes were significantly different by age, gender and regions. Women and age 50 years and over had significantly higher potassium intakes than men and other age groups. The average Na/K ratio was $2.89{\pm}0.01$ and was highest in men and in the age group of 19-49 years. The major sources of dietary sodium were soup and stew, followed by Kimchi, noodles and dumpling, pickled vegetables and seasonings, which represented 63.1 % of total sodium intakes. Soup and stew or Kimchi were the primary sources of dietary sodium intake. The major sources of dietary potassium were cooked rice, followed by soup and stew, Kimchi, fruits and beverages. Conclusions: Sodium and potassium intakes and the major sources of those were significantly different by gender, age groups and regions. Therefore, different approaches based on gender, age and regions are needed to decrease sodium intake and increase potassium intake.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.60 no.1
• /
• pp.97-106
• /
• 2015

Platycodon grandiflorum, commonly known as Doraji in Korea, has a wide range of pharmacologic properties, such as reducing adiposity and hyperlipidemia, and antiatherosclerotic effects. However, the mechanisms underlying these effects remain unclear. In order to profile proteins from the nodal segment, callus, root and shoot, high throughput proteome approach was executed in the present study. Two dimensional gels stained with CBB, a total of 84 differential expressed proteins were confirmed out of 839 protein spots using image analysis by Progenesis SameSpot software. Out of total differential expressed spots, 58 differential expressed protein spots (${\geq}$ 2-fold) were analyzed using MASCOT search engine according to the similarity of sequences with previously characterized proteins along with the UniProt database. Out of 58 differential expressed protein, 32 protein spots were up-regulated such as ribulose-1,5-bisphosphate carboxylase, endoplasmic oxidoreductin-1, heat stress transcription factor A3, RNA pseudourine synthase 4, cysteine proteinase, GntR family transcriptional regulator, E3 xyloglucan 6-xylosyltransferase, while 26 differential protein spots were down-regulated such as L-ascorbate oxidase precursor, late embryogenesis abundant protein D-34, putative SCO1 protein, oxygen-evolving enhancer protein 3. However, frequency distribution of identified proteins using iProClass databases, and assignment by function based on gene ontology revealed that the identified proteins from the explants were mainly associated with the nucleic acid binding (17%), transferase activity (14%) and ion binding (12%). In that way, the exclusive protein profile may provide insight clues for better understanding the characteristics of proteins and metabolic activity in various explants of the economically important medicinal plant Platycodon grandiflorum.

• Proceedings of the KOSOMBE Conference
• /
• v.1998 no.11
• /
• pp.249-250
• /
• 1998

In this study, we modeled moving-actuator type Total Artificial Heart (TAH) with cardiovascular system as a form of electric circuit. The bronchial circulation, important for the imbalance between the left cardiac output and the right one, was considered and added to the model. In the model, the relations of hemodynamic variables, just as blood pressures, volumes, or flow rates of each part of body, can be expressed as simultaneous first order ordinary differential equations. To solve the equations by the numerical analysis, Runge-Kutta forth order approximation method was adopted. The simulation software (SimTAH), implemented in C++ as a window-based application program, was developed to display the hemodynamic variables and to receive control inputs from users. SimTAH was evaluated by comparison of the simulation results with the results of mock-circulation tests, in vitro.

• Journal of Fashion Business
• /
• v.6 no.5
• /
• pp.136-150
• /
• 2002

In this study, we proposed a method to be standing customers as the supporting system for the improvement of fashion garment industry which was the marginal growth getting into full maturity of market. As for the customer creation method of Fashion garment company is developing a marketing program to be standing customer as customer scoring to estimate a existing customer‘s buying power, and figure out minimum fixed sales of company to use a future purchasing predict. This study was a result of data from total sixty thousands data to be created for the 11 months from september. 2000 to July. 2001. The data is part of which the company leading the Korean fashion garment industry has a lot of a customer purchasing history data. But this study used only 48,845 refined purchased data to discriminate from sixty thousands data and 21,496 customer case with the exception of overlapping purchased data among of those. The software used to handle sixty thousands data was SAS e-miner. As the analysis process is put in to operation the analysis of the purchasing customer’s profile firstly, and the second come into basket analysis to consider the buying associations for Association goods, the third estimate the customer grade of Customer loyalty by 3 ways of logit regression analysis, decision tree, Artificial Neural Network. The result suggested a method to be estimate the customer loyalty as 3 independent variables, 2 coefficients. The 3 independent variables are total purchasing amount, purchasing items per one purchase, payment amount by one purchasing item. The 2 coefficients are royal and normal for customer segmentation. The result was that this model use a logit regression analysis was valid as the method to be estimate the customer loyalty.

• Journal of the Korean Society of Tobacco Science
• /
• v.20 no.2
• /
• pp.191-197
• /
• 1998

Discriminant analysis using near infrared spectra derived from Korean Flue-cured(KF) and American Flue-cured(AF), and also Korean Burley(KB) and American Burley(AB) tobacco was done to classify flue-cured and burley tobacco as either grown in Korea or grown in the USA. Samples were scanned in the wavelength of 400 ～ 2500 nm by near infrared analyzer(NIRSystem Co., model 6500). The discrimination equations for flue-cured and burley tobacco were developed using partial least square 2 method in Infrasoft International NIRS 3 software package. KF samples used for the development of the discrimination equations were higher contents of total sugar, crude ash and chlorine, and higher value of leaf density and brightness, but lower contents of nicotine, total nitrogen and ether extracts, and higher value of redness than those of AF samples. KB samples were higher contents of nicotine, crude ash and chlorine, but lower contents of ether extracts and value of brightness than those of AB samples. On 3 dimensional graph drawn with 3 principal component scores calculated with 3 principal component from KF and KB sample spectra, KF sample spectra were significantly different from AF, and also KB sample spectra were significantly different from AB. The discrimination equations of flue-cured and burley were developed with 3 principal component, respectively. The discrimination equations for flue-cured and burley had a standard error of 0.03 and 0.04, and a R2 of 0.88 and 0.84, respectively. The tobacco samples used for the development of discrimination equation were perfectly classified as KF and AF by flue-cured discrimination equation, and also perfectly classified KB and AB by burley discrimination equation, respectively. The correct classification rates of KF and AF samples not used for the development of discrimination equations were 9S % (828 out of 869 samples) and 98 % (98 out of 100 samples) by flue-cured discrimination equations, and KB and AB samples were 94%(345 out of 368 samples) and 100%(42 out of 42 samples) by burley discrimination equations, respectively.