• 한국식품영양과학회지
• /
• 제29권2호
• /
• pp.235-240
• /
• 2000

Inhibitory effects of cockle extracts on carcinogen-induced cytotoxicity in C3H/10T1/2 cells were studied. Soup (62$\mu\textrm{g}$/mL), solubility (28$\mu\textrm{g}$/mL) and liposolubility (9 $\mu\textrm{g}$/mL) of the cockle inhibited 3-methyl-cholanthrene(MCA)-induced cytotoxicity in C3H/10T1/2 cells by 53 and 94%, respectively. These results suggest that the extracts cockle might have anticarcinogen-induced cytotoxicity of C3H/10T1/2 cells. The effects of cockle extracts on the immune response related to its antitumor activity in vitro and in vivo were investigated. The cockle extracts showed a direct cytotoxic effect on sarcoma-180 cells, tumor cells in vitro. Soup (0.49 mg/mL), solubility (0.11 mg/mL) and liposolubiliy (0.05 mg/mL) of the cockle markedly decreased the total numbers of sarcoma-180 cells, but not their viability. The phagocytic acitivity of peritoneal macrophage of mice was significantly augmented by these extracts of the cockle compared with that of control in vivo. These extracts also raised the phagocuytic index, indicating that the number of phagocytize dmicrobes per macrophage increased. Thus, cockle extracts might show a antitumor activity by enhancing the phagocytic cell activities.

• 대한족부족관절학회지
• /
• 제23권1호
• /
• pp.31-34
• /
• 2019

Chondroblastoma is a rare benign tumor that produces giant cells and cartilage matrix. The tumor occurs in people between 10 and 25 years with slightly higher incidence in males. The condition occurs in the proximal epiphysis of the tibia and humerus, distal epiphysis of the femur, but its occurrence in the talus is relatively rare, accounting for 4% of the total number of chondroblastoma cases. Chondroblastoma is often misdiagnosed as a primary aneurysmal bone cyst, giant cell tumor, chondromyxoid, and lesion of a secondary aneurysmal bone cyst by fibrous dysplasia. The most commonly used surgical method for chondroblastoma is broad curettage with bone grafting. In general, an aneurysmal bone cyst is associated with a second degree chondroblastoma, which is approximately 20%. Chondroblastoma of the talus and secondary aneurysmal bone cysts can be misdiagnosed as primary aneurysmal bone cysts. This paper reports a case of a young male patient with chondroblastoma of the talus, which was initially misdiagnosed as an aneurysmal bone cyst with involvement of the talo-navicular joint.

• Safety and Health at Work
• /
• 제12권4호
• /
• pp.424-431
• /
• 2021

Background: This study aims to introduce the formulation of the regulation for the selection of respirators for accident preparedness chemicals (APCs) according to chemical workplace situations and to determine on-site applicability. Methods: Workplaces were grouped into seven work categories, and APCs were classified into six groups to select adequate respirators. A survey was conducted to enhance the understanding of work situations and adequate respirators. The total number of subjects surveyed in 2018 was 201 managers and handlers, and that in 2019 was 91 handlers and 204 managers. Results: Adequate respirators were allocated to each cell using the matrix method. The study observed an overall lack of understanding of work situations, especially in the operation of open devices, which was the highest at 32.7%. Despite its implementation in 2015, 17.6% and 25.0% of the managers and APCs handlers, respectively, were unaware of the regulations for selecting respirators. Only 70.4% of the APCs handler wore respirators in compliance with regulations. Conclusion: The method for selecting respirators according to work situations using the matrix method is considered reasonable. Thus, this study suggests that the development of educational contents and reinforcing education should be essential steps to increasing awareness of regulations.

• Archives of Plastic Surgery
• /
• 제50권2호
• /
• pp.160-165
• /
• 2023

Background The number of cosmetic and reconstructive surgeries that use breast implants is increasing in Korea. Recently, it has been reported that breast implant-associated anaplastic large-cell lymphoma is related to textured breast implants, and interest in classification according to the texture of breast implants is increasing. However, there is currently no clear and unified classification. In particular, the definition of "microtextured" is highly varied. In this study, we retrospectively investigated and analyzed the clinical outcomes of smooth and microtextured breast implants. Methods A retrospective chart review of all patients who underwent breast augmentation surgery with smooth and microtextured silicone gel implants between January 2016 and July 2020 was performed. We retrospectively analyzed implant manufacturer, age, body mass index (BMI), smoking status, incision location, implant size, follow-up period, complications, and reoperation rate. Results A total of 266 patients underwent breast augmentation surgery, of which 181 used smooth silicone gel implants and 85 used microtextured silicone gel implants. Age, BMI, smoking status, implant size, and follow-up period were not significantly different between the two groups. Similarly, complications and reoperation rates were not significantly different between the two groups. Conclusion It is important to provide information regarding the clinical risks and benefits of breast implants to surgeons and patients through a clear and unified classification according to the texture of the breast implant.

• Anatomy and Cell Biology
• /
• 제56권4호
• /
• pp.428-434
• /
• 2023

Pulmonary veins (PVs) and their myocardial sleeves play an important role in the development of atrial fibrillation. Hence, detailed knowledge of PV anatomy is required to improve the procedural success rate and prevent complications during cardiac procedures. The aim of this study was to evaluate the PV anatomy along with anatomical variations in the Indian population. Total 100 formalin fixed cadaveric hearts were examined. The number and pattern of the PVs were observed along with the measurement of their horizontal and vertical diameters. The ovality index for each PV was calculated. Classical PV pattern was observed in 62% cases. Variant pattern like additional right middle PV pattern and left common PV pattern were found in 20% and 10% cases respectively. A separate pattern with presence of both right middle PV and left common PV was observed in 6% cases. In the classical pattern right superior PV was the largest followed by right inferior, left superior and left inferior PV. The additional right middle PV had the smallest diameter whereas the left common PV had the largest diameter. Almost all the veins had greater vertical diameters in comparison to horizontal diameters. The variant PVs were oval and had greater ovality index compared to the normal PVs. In classical pattern 54.8% hearts whereas in variant pattern 79% hearts had one or more oval PV. The given data can help clinicians for planning and execution of various interventional and electrophysiological procedures involving PVs.

• Anatomy and Cell Biology
• /
• 제57권2호
• /
• pp.305-315
• /
• 2024

Vitronectin (VN) is an extracellular matrix protein with a crucial role in regulating bone remodeling. In this study, we aimed to investigate the effect of VN deficiency in a mouse model of osteoporosis induced by ovariectomy (OVX). The findings revealed that the absence of VN led to an increase in the activity of tartrate-resistant acid phosphatase (TRAP), a marker for osteoclasts, in the plasma of OVX-operated mice. TRAP staining further demonstrated that VN deficiency resulted in a higher number of osteoclasts within the femurs of OVX-operated mice. X-ray micro-computed tomography analysis of the femurs in OVX-operated mice indicated that VN deficiency significantly suppressed the OVX-induced increase of marrow area and total volume of bone. Additionally, we assessed structural model index (SMI) and degree of anisotropy (DA) as indices of osteoporosis. The results showed that VN deficiency effectively attenuated the OVX-induced increase in SMI and DA among OVX-operated mice. In summary, our study demonstrates the vital role of VN in regulating osteoclastogenesis and bone remodeling in the mouse model of osteoporosis.

• 미생물학회지
• /
• 제33권4호
• /
• pp.262-266
• /
• 1997

산성강하물의 영향을 받는 대전공단지역과 영향을 받지 않는 청정지역인 대전 계족산 자연휴양림에서 자라는 밤나무(Castanea crenata)의 잎표면에서 서식하는 총세균수, 생존세균수, 종속영양세균수, 내산성세균수를 1996년 8월부터 1997년 8월까지 5회에 걸쳐 조사하였다. 공단지역 잎표면 평균 총세균수, 생존세균수 및 종속영양세균수는 각각 $9.9{\times}10^5cell/cm^2$, $1.6{\times}10^6cell/cm^2$, $7.1{\times}10^3cfu/cm^2$로서 청정지역에 비하여 각각 1.5배, 2배, 2.6배 정도로 관찰되었다. MPN법으로 측정한 pH 5.6에서의 잎표면 내산성세균수는 공단지역 $3.3{\times}10^4$, 청정지역 $3.4{\times}10^4MPN/cm^2$로 거의 같았고, pH 4.0에서의 내산성세균수는 공단지역에서 $1.9{\times}10^{-1}MPN/cm^2$인 반면 청정지역세서는 전혀 검출되지 않았다. pH 3.0에서의 내산성 잎표면세균수는 공단지역과 청정지역의 잎권 어느 곳에서도 검출되지 않았다. 한편 계절별 잎포면세균수의 분포는 대체로 잎이 나기 시작하여 크기가 가장 작은 5월에 최대를, 그리고 낙엽이 지는 11월에 최소를 나타내었다. 이런 결과는 공단지역의 대기오염물질의 침적이 주변의 식물 잎표면 세균수를 감소시키지는 않으며, 특히 산성강하물의 영향으로 내산성세균수가 증가함을 보여주고 있다.

• 대한전자공학회논문지TC
• /
• 제42권8호
• /
• pp.17-24
• /
• 2005

본 논문에서는 Blind 채널 등화를 위한 error feedback 필터를 갖는 Decision Feedback Equalizer(DFE) 구조의 등화기를 설계하였다. 제안하는 등화기는 Least Mean Square(LMS) 알고리즘과 Multi-Modulus Agorithm(MMA)을 이용하였으며 64/256 QAM을 위해 설계되었다. 기존의 MMA 등화기는 두개의 transversal 필터를 이용하거나 feedforward와 feedback 필터를 이용하는 반면에 제안하는 등화기는 feedforward와 feedback 그리고 error feedback 필터를 사용하여 채널 적응 성능을 향상시켰으며 탭 수를 감소시켰다. 제안하는 구조는 $SPW^{TM}$ 툴을 이용 시뮬레이션을 수행하여 성능을 개선시킬 수 있었다. 그리고 VHDL을 이용해 시뮬레이션을 수행하였으며 논리 합성은 0.25um 셀 라이브러리를 이용하였다. 설계한 등화기는 약 19만 게이트 수와 15MHz의 동작속도를 보였다 또한 FPGA 칩을 내장한 이뮬레이션 보드를 사용하여 성능 검증을 수행하였다.

• 한국멀티미디어학회논문지
• /
• 제2권3호
• /
• pp.329-338
• /
• 1999

본 논문에서는 무선 ATM의 MAC 프로토콜로 DTDD!PS(Dynamic Time Division Duplex using PolV S Select scheme)을 제안한다 DTDD!PS 프로토콜의 기본 개념은 기지국과 단말로 구성된 무선 ATM 라디오 셀올 큐잉 시스템으로 고려하는 것이다. 기지국에 있는 MAC 제어기는 각 단말의 QoS(Quality of Service)를 만족시키기 위해 각 단말의 순간적인 대역요구의 수용에 초점을 둔다. 이를 위해 기지국에서는 각 단말로부터 동적 매개변수를 받아 이것을 이용하여 기지국에서는 각 단말들의 접속 상태를 통제하고 슬롯 단위로 대역의 동적인 할당을 한다. 이러한 방법으로 유선 ATM 보다 낮은 전송률을 갖는 무선 ATM에서 실시간 서비스의 Q QoS를 만족시킬 수 있게된다. DTDD/PS 프로토콜의 성능을 평가하기 위해서 시율레이션을 수행하였다. 그 결과 전송률이 251이bps인 시스템에서 음성 단말과 데이터 단말이 공폰된 환경에 대한 시률레이션올 수행한 결과 음성 단말의 증가에 따라 데이터 트래픽의 지연이 급격히 증가하는것을 볼 수 있었다. 그러나, 데이터 단말의 부하가 증가하더라도 음성단말에 우선 순위를 주고 있는 상황에서 동시통화 음성단말의 수는 크게 변화가 없다. 따라서 멀티미디어 트래픽과 같은 다양한 QoS를 갖는 트래픽이 공존하는 상황에서 DTDD/PS 프로토콜이 효과적으로 적용될 것올 예상할 수 있다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제22권8호
• /
• pp.1117-1123
• /
• 2009

This study investigated the effects of IGF-I and EGF on the development of blastocysts or hatched blastocysts during the in vitro culture of embryos from immature porcine oocytes. After the in vitro maturation and fertilization of cumulus-oocyte complexes (COCs) and their culture in vitro in PZM3 medium, we examined the embryo development rate for 168 h. When different concentrations of IGF-I (0, 1, 10, 20 ng/ml) were supplemented to fertilized porcine embryos in vitro, there were no significant differences in cleavage rate, blastocyst development rate or blastocyst hatching rate among the treated groups. On the other hand, when different concentrations of EGF (0, 1, 10, 20 ng/ml) were supplemented to the in vitro culture medium, blastocyst development rate was highest in the group in which EGF was not supplemented and, specifically, it was higher than in the 20 ng/ml treatment group (p<0.05). When 10 ng/ml IGF-I and 1 ng/ml EGF were supplemented separately or simultaneously, there were no significant differences among the treated groups in blastocyst hatching rate and the number of cells in each condition. This study demonstrated that the addition of IGF-I and EGF into PZM3 medium did not enhance development of the blastocyst stage and total cell number in blastocysts.