• Title/Summary/Keyword: time-dependent effect

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Effects of Pinus densiflora on soil chemical and microbial properties in Pb-contaminated forest soil

  • Kim, Sung-Hyun;Lee, In-Sook;Kang, Ho-Jeong
    • Journal of Ecology and Environment
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    • v.34 no.3
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    • pp.315-322
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    • 2011
  • We investigated the effect of Pb uptake by Pinus densiflora and the Pb fraction in forest soil. We also investigated the change in soil physicochemical characteristics, microbial activity, and root exudates of Pinus densiflora in Pb-contaminated soils. Three-year-old pine seedlings were exposed to 500 mg/kg Pb for 12 months. The metal fractions were measured using sequential extraction procedures. Additionally, factors that affect solubility (three soil enzyme activities and amino acids of root exudate compounds) were also determined. The results showed that Pb contamination significantly decreased enzyme activities due to soil characteristics. In addition, organic matter, nitrate content, and Pb concentration were time dependent. The results indicate that changes in the Pb fraction affected Pb uptake by pine trees due to an increase in the exchangeable Pb fraction. The concentrations of organic acids were higher in Pb-spiked soil than those in control soil. Higher rhizosphere concentrations of oxalic acid resulted in increased Pb uptake from the soil. These results suggest that pine trees can change soil properties using root exudates due to differences in the metal fraction.

Dynamic Modeling of Building Services Projects: A Simulation Model for Real-Life Hospital Project

  • Abhishek, V.;Jagadeesh, P.
    • Journal of Construction Engineering and Project Management
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    • v.3 no.3
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    • pp.35-41
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    • 2013
  • All infrastructure projects are said to be inter-dependent, uncertain and labour-intensive in nature. There is no exception for building services sub sector. For a real time project such as 'The construction, extension and refurbishment of Employees' State Insurance Corporation (ESIC) Hospital at Tirupathy, India with total area of 45,000 square feet at an estimated cost of 1100 million rupees, a generic process model is developed to simulate the effect of set of identified variables on construction project. The 'Stocks and Flows' of dynamic model affords relevant insights to project managers, who apply this knowledge when designing better performance through more appropriate project planning. It is concluded from the model-based approach that building services works can be improved through specific better focussed managerial efforts, such as an increasing coordination effectiveness at the planning stage, clarifying prerequisite conditions prior to installations. Otherwise, pending works arising from work clashes can lead to knock-on effects resulting in productivity constraints and pressures, as well as more rework and demolition. Current study reveals that the model enables deep insight into various interdependent processes, their by improving construction performance levels, by addressing the dynamics of design errors and defective works, and recovering delayed schedule.

The Effect of Lumbar Stabilization Exercises with Neurodynamic Techniques on Lumbar Muscular Strength and Oswestry Disability Index in Lumbar Disc Herniation Patient's (요추 안정화 운동과 결합된 신경역동학기법이 요추 추간판 탈출증 환자의 요부근력과 오스웨스트리 장애지수에 미치는 영향)

  • Mo, Min-sang;Park, Hyun-sik
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.22 no.1
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    • pp.1-7
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    • 2016
  • Background: The purpose of this study was to investigate the effects of lumbar stabilization exercise with neurodynamic techniques on lumbar muscular strength and Oswestry index in lumbar disc herniation patient. Method: The Lumbar stabilization exercise with neurodynamic techniques was performed by 30 pt's in G hospital. The subjects were randomly organized into a study group 15 and control group 15. The exercises and neurodynamic technique were conducted for 40 minutes and, 3 times a week (total 24 times for 8 weeks). General characteristics of the Lumbar muscular strength and Oswestry disability index (ODI) were measured before the training and at 4 weeks and 8 weeks after the intervention. Comparison of the time dependent variable for each group was Calculated by a one way repeated analysis of variance (ANOVA). Comparison between the two groups was Calculated by an analysis of covariance (ANCOVA). Result: There was a significant difference in the Lumbar muscular strength and ODI (p<.05). Similarly in the inter-group analysis, significant differences (p<.05) occurred. Conclusion: In this study, we demonstrated that lumbar stabilization exercises with neurodynamic techniques are an effective therapy for Lumbar muscular strength and ODI in lumbar disc herniation patient's.

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Evaluating Unsaturated Hydraulic Properties of Compacted Geomaterials in Road Foundations (II) : Numerical Analysis (다져진 도로기초 재료의 불포화투수특성 평가 (II) : 수치해석)

  • Sung, Yeol-Jung;Park, Seong-Wan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.1D
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    • pp.83-90
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    • 2011
  • A need still exists that the unsaturated condition is to be considered when evaluating the infiltration and drainage capacity for compacted geomaterials in road foundation or embankments. For this reason, numerical analysis were used to analyze the time-dependent unsaturated infiltration and drainage condition depending on various geomaterial types. Therefore, laboratory data from the soil-water characteristic curve tests on geomaterials were adopted from previous studies. In addition, the unsaturated permeability was estimated using SWCC. Then the infiltration and drainage performance of unsaturated compacted soils were evaluated under various conditions based on the proposed method. The results demonstrated that the effect of initial suction and SWCC path on each material could be substantial and the proper application on analysis is very important to enhance the prediction on each capacity.

Effect of Rutin on Adhesion Molecules Expression and NO Production Induced by $\gamma$-irradiation in Human Endothelial cells

  • Son, Eun-Wha;Lee, Kang-Ro;Rhee, Dong-Kwon;Pyo, Suh-Kneung
    • Biomolecules & Therapeutics
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    • v.9 no.3
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    • pp.156-161
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    • 2001
  • Inflammation is a frequent radiation-induced following therapeutic irradiation. Treatment of human umbilical endothelial cells (HUVEC) with ${\gamma}$-irradiation (${\gamma}$IR) induces the expression of adhesion proteins such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin. Since the upregulation of these proteins on endothelial cell surface has been known to be associated with inflammation, interfering with the expression of adhesion molecules is an important therapeutic target. In the present study, we demonstrate that bioflavonoid rutin inhibits ${\gamma}$IR induced expression of ICAM-1, VCAM-1, and E-selectin on HUVEC in a dose- and time dependent manner. Rutin also inhibited ${\gamma}$IR induced production of NO. These data suggest that rutin has therapeutic potential for the treatment of various inflammatory disorder associated with an increase of endothelial leukocyte adhesion molecules.

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Scavenging Effects of Tea Catechins on Superoxide and Hydroxy Radical

  • Park, Jaeil;Chen, Liuji;Yang, Xianqiang;Shen, Shengrong;Wang, Yuefei;Ho, Ryu-Beung
    • Journal of Life Science
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    • v.12 no.2
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    • pp.75-79
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    • 2002
  • Tea catechins, the most important compounds in tea polyphenols, can efficiently scavenge superoxide anion free-radical ($O_2$.), hydroxyl radical. (.OH) The mechanism of scavenging active oxygen free radicals was investigated by ESR spin trapping technique and Chemiluminescence. Results showed that various tea catechins constitute an antioxidant cycle in accordance with the decreasing order of the first reductive potential, and produce the effect of cooperative strength each other. Esterificated catechins could scavenge active oxygen free radicals more effectively than the non-esterificated ones. When.OH and $O_2$.- were scavenged by (-)-epigallocatechin gallate [(-)- EGCG], the stoichiometric factors were 6, and the rate constants of scavenging reaction reached $7.71{\times}10^6$ and $3.52{\times}10^{11}$ L $mmol^{-1}s^{-1}$, respectively. In the mean time, tea catechins could scavenge superoxide anion fiee radical ($O_2$-.) and hydroxyl radical (.OH) in a dose dependent manner. But at higher concentration or pH value, tea catechins can induce the prooxidant.

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Effects of Indomethacin on Development and Hatching of Mouse Embryo (Indomethacin이 생쥐 착상전 배아의 발생 및 부화에 미치는 영향)

  • Cheon, Yong-Pil;Gye, Myung-Chan;Kim, Chung-Hoon;Kim, Moon-Kyoo
    • Clinical and Experimental Reproductive Medicine
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    • v.24 no.1
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    • pp.35-42
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    • 1997
  • The present study was designed to define the role of prostaglandin in the development and hatching of mouse embryo. The effects of indomethacin, an inhibitor of prostaglandin synthesis, on the development and hatching of morula and blastocyst were examined. In early morula stage, embryos were degenerated significantly at 100 ${\mu}M$ and 200 ${\mu}M$ indomethacin. However, the viability of embryos was not influenced by concentration in any other embryonic stages. In all embryonic stages, the hatching was suppressed with concentration dependent manner, but expansion was not suppressed. Particularly, in 84h embryos post hCG injection, the hatching was suppressed significantly compared with post hCG 72h or 96h embryos. When embryos were treated with 100 ${\mu}M$ indomethacin for a specific time (12h) in according to the development stage, the hatching was suppressed all groups. These suppressional effect was decreased as embryonic development stage was progressed. However, the expansion was not affected in all treatment group. This study suggests that hatching-related metabolic substances are synthesized from morula stage and intraembryonic signaling mediated prostaglandin was important for development and hatching of mouse embryo.

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Analysis of Reported Study on the Rehabilitation Therapy for Patients with Total Knee Arthroplasty (슬관절 전치환술 환자에게 적용한 재활요법 연구논문 분석)

  • Jun, Jum-Yi
    • Korean Journal of Adult Nursing
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    • v.24 no.3
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    • pp.253-265
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    • 2012
  • Purpose: The focus of this research was a systematic review of published articles and theses for a degree in Korea and foreign countries on rehabilitation therapy for patients with total knee arthroplasty (TKA). Methods: The literature until December in 2011 were searched and the data basis included Medline, CINAHL, KERIS, National Library of Korea, and National Assembly Library web sites. Words for the search were TKA or TKA and rehabilitation. Studies included randomized controlled and non-equivalent control group pretest-posttest design. 31 studies were analyzed focusing on type, application method, dependant variable and effect using descriptive statistics. Results: Seventeen rehabilitation therapies and forty-nine dependant variables were used. The application methods of rehabilitation therapy were diverse. The most frequently used rehabilitation type was an exercise therapy and a pain/discomfort was the most frequently used dependant variable. The effects of rehabilitation therapy were inconsistent. Conclusion: The individualized rehabilitation therapy must be comprised of type, time, frequency, period and duration. Attention must be made as to the research design, especially the better measurement of the dependent variables. This review may serve as a base for future research.

Survival of Colorectal Cancer in the Presence of Competing-Risks - Modeling by Weibull Distribution

  • Baghestani, Ahmad Reza;Daneshvar, Tahoura;Pourhoseingholi, Mohamad Amin;Asadzadeh, Hamid
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1193-1196
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    • 2016
  • Background: Colorectal cancer (CRC) is the commonest malignancy in the lower gastrointestinal tract in both men and women. It is the third leading cause of cancer-dependent death in the world. In Iran the incidence of colorectal cancer has increased during the last 25 years. Materials and Methods: In this article we analyzed the survival of 447 colorectal patients of Taleghani hospital in Tehran using parametric competing-risks models. The cancers of these patients were diagnosed during 1985 - 2012 and followed up to 2013. The purpose was to assess the association between survival of patients with colorectal cancer in the presence of competing-risks and prognostic factors using parametric models. The analysis was carried out using R software version 3.0.2. Results: The prognostic variables included in the model were age at diagnosis, tumour site, body mass index and sex. The effect of age at diagnosis and body mass index on survival time was statistically significant. The median survival for Iranian patients with colorectal cancer is about 20 years. Conclusions: Survival function based on Weibull model compared with Kaplan-Meier survival function is smooth. Iranian data suggest a younger age distribution compared to Western reports for CRC.

Stochastic ground-motion evaluation of the offshore Uljin Earthquake (울진앞바다 지진( '04. 5. 29, M=5.2)의 추계학적 지진동 평가)

  • Yun, Kwan-Hee;Park, Dong-Hee;Choi, Weon-Hack;Chang, Chun-Jung
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2005.03a
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    • pp.18-25
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    • 2005
  • Stochastic ground-motion method is adopted to simulate horizontal PGA values for the offshore Uljin earthquake recorded at nationwide seismic stations. For this purpose, the Fourier spectra are calculated at every stations based on comprehensive results of wave propagation and site effect which were previously revealed through inversion process applied to large accumulated spectral D/B. In addition, the apparent source spectrum of the offshore Uljin earthquake is estimated by removing the path and site response from the observed spectra. The distance dependent time-duration model is revised by iteratively fitting the PGA values generated by using the raw spectra data to the observed PGA data. The stochastic ground-motion method predicts the observed PGA values within a error of ${\sigma}_{log10}=0.1$. Transfer functions of a site relative to another site are estimated based on the error residual of the inversion results and used to convert PGA values at multiple stations to expected PGA values at a reference station of TJN. The converted PGA values can be used as basic data to evaluate the ground-motion attenuation relations developed for seismic hazard analysis that concerns the large damaging earthquakes.

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