• The Korean Journal of Pain
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• v.9 no.1
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• pp.283-287
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• 1996

Recently, continuous epidural catheter insertion is usually employed in operation and chronic pain control. Delayed migration of an extradural catheter into subdural space or subarachnoid space is a rare but life threatening complication of continuous epidural catheter insertion, especially with out patients. The symptoms may include lower extremity weakness, hypotension, drowsy and respiratory depression. We experienced two cases of lower extremity paralysis due to delayed migration into subdural or subarachnoid spaces at our pain clinic. The tecnical procedures for continuous epidural catheterization went smoothly without any complications. However, clinical signs of lower extremity paralysis and sensory loss developed gradually, about 2 hours and 30 minutes after the continuous epidural injection. Two cases were confirmed by subdurogram and myelogram.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6935-6940
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• 2013

Background: This study aimed to develop a prognostic model in patients with early-stage cervical squamous cell carcinoma based on clinicopathological features, including invasive margin characteristics. Materials and Methods: Clinicopathological features and outcomes of 190 patients with FIGO stage IB-IIA cervical squamous cell carcinoma treated by surgery were collected and analyzed for factors associated with tumor recurrence. In addition to well-recognized pathological risk factors, the pathological characteristics of invasive margin (type of invasive pattern and degree of stromal desmoplasia and peritumoral inflammatory reaction) were also included in the analysis. Multiple scoring models were made by matching different clinicopathological variables and/or different weighting of the score for each variable. The model with the best performance in the prediction of recurrence and decreased survival was selected. Results: The model with the best performance was composed of a combined score of invasive pattern, lymphovascular space invasion (LVSI), and degree of inflammatory reaction and stromal desmoplasia (total score =10). Compared to those with score ${\leq}8$, the patients with score 9-10 had a significantly higher recurrence rate in the overall group (p<0.001) and the subgroup without adjuvant therapy (p<0.001), while the significance was marginal in the subgroup with adjuvant therapy (p=0.069). In addition, the patients with score 9-10 had a higher rate of tumor recurrence at distant sites (p=0.007). The disease-free survival was significantly lower in the patients with score 9-10 than those with score ${\leq}8$ among the overall patients (p<0.001), in the subgroup without adjuvant therapy (p<0.001), and the subgroup with adjuvant therapy (p=0.047). Conclusions: In this study, a prognostic model based on a combination of pathological characteristics of invasive margin and LVSI proved to be predictive of tumor recurrence and decreased disease-free survival in patients with early-stage cervical squamous cell carcinoma.

• Korean Journal of Environment and Ecology
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• v.30 no.2
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• pp.271-276
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• 2016

Though various studies have analyzed the impact of physically being in the forest, consideration of the time factors is omitted in many of them. Since space and time mutually affect each other, the effects that resulted by the space factor can change when the time factor is introduced. In this paper, the focus was made on how the time spent in the forest influences the four resulting factors: live experiences, flow experiences, health perception and inner psychological perception. This research is based on the surveys taken from April to October, 2014. The focus of the questionnaire was to measure 'Live Experience (LE)', 'Flow (FL)', 'Health Perception (HP)' and 'Inner Psychological Perception (IPP)' levels among the participants. The respondents of the survey aged between 40 and 70, participating in Forest or ecological courses, living in the Northern area of Chungchungnam-do province of Korea. Additionally their past experiences ranged from as little as one year to as long as twenty years in forest related fields. It will be shown that the time spent in the forest affects the levels of LE, FL, HP, IPP, increasing them in proportion to the time with statistical significance. This result would be useful not only for those who are in charge of creating forest healing programs but also for people who study forest healing. Because the time spent in the forest influences the levels of LE, FL, HP, IPP, the forest healing programs will benefit by taking this result into consideration.

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.2
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• pp.29-37
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• 2015

Purpose: The purpose of this study was to investigate the factors that make the bathroom experience an inconvenient one for stroke patients, including the use of basic materials to provide an effective and individualized bathroom environment. Method: The survey was conducted from May 20 to June 20, 2014 on 81 stroke patients. The questionnaire is composed of the following: general factors of respondents, degree of inconvenience of general bathroom usage, and inconvenient factors. The questions on inconvenient factors of bathroom usage are comprised of 20 questions in a 5-point Likert scale. Result: The degree of inconvenience of bathroom usage results showed that the group of patients using wheelchairs experience more inconvenience than the group of patients without wheelchairs. The inconvenient factors between two groups are shown to have significant differences in the door sill, the location of the mirror, the chair for showering, transferring to the bathtub, slippery floor, the location of cabinets, door width, shower space, the location of shower booth, and the safety handle on the wall and toilet (p<.05). Conclusion: The result of this research shows that the inconvenient factors in the bathroom experience stroke patients vary depending on the use of wheelchair. The result may be utilized as therapeutic basic materials provide an effective bathroom environment to stoke patients in future.

• Journal of Korean Neurosurgical Society
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• v.57 no.5
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• pp.315-322
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• 2015

Intracranial germ cell tumors (ICGCT) occur in 2-11% of children with brain tumors between 0-19 years of age. For treatment of germinoma, relatively low radiation doses with or without chemotherapy show excellent 10 year survival rate of 80-100%. Past studies showed that neoadjuvant chemotherapy combined with focal radiotherapy resulted in unacceptably high rates of periventricular tumor recurrence. The use of generous radiation volume which covers the whole ventricular space with later boost treatment to primary site is considered as standard treatment of intracranial germinomas. For non-germinomatous germ cell tumors (NGGCT), 10-year overall survival rate is still much inferior than that of intracranial germinoma despite intensive chemotherapy and high-dose radiotherapy. Craniospinal radiotherapy combined with cisplatin-based chemotherapy provides the best treatment outcome for NGGCT; 60-70% of overall survival rate. There is a debate on the surgical role whether surgery can contribute to improved treatment outcome of NGGCT when added to combined chemoradiotherapy. Because higher dose of radiotherapy is required for treatment of NGGCT than for germinoma, it is tested whether whole ventricular irradiation can replace craniospinal irradiation in intermediate risk group of NGGCT to minimize radiation-related late toxicity in the recent studies. To minimize the treatment-related neural deficit and late sequelae while maintaining long-term survival rate of ICGCT patients, optimized administration of chemotherapy and radiotherapy should be selected. Use of technically upgraded radiotherapy modalities such as intensity-modulated radiotherapy or proton beam therapy is expected to bring an improved neurocognitive outcome with longitudinal assessment of the patients.

• Journal of Periodontal and Implant Science
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• v.46 no.4
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• pp.244-253
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• 2016

Purpose: The aim of this study was to characterize the healing in the grafted calvarial defects of rats after adjunctive hyperbaric oxygen therapy. Methods: Twenty-eight male Sprague-Dawley rats (body weight, 250-300 g) were randomly divided into two treatment groups: with hyperbaric oxygen therapy (HBO; n=14) and without HBO (NHBO; n=14). Each group was further subdivided according to the bone substitute applied: biphasic calcium phosphate (BCP; n=7) and surface-modified BCP (mBCP; n=7). The mBCP comprised BCP coated with Escherichia-coli-derived recombinant human bone morphogenetic protein-2 (ErhBMP-2) and epigallocatechin-3-gallate (EGCG). Two symmetrical circular defects (6-mm diameter) were created in the right and left parietal bones of each animal. One defect was assigned as a control defect and received no bone substitute, while the other defect was filled with either BCP or mBCP. The animals were allowed to heal for 4 weeks, during which those in the HBO group underwent 5 sessions of HBO. At 4 weeks, the animals were sacrificed, and the defects were harvested for histologic and histomorphometric analysis. Results: Well-maintained space was found in the grafted groups. Woven bone connected to and away from the defect margin was formed. More angiogenesis was found with HBO and EGCG/BMP-2 (P<0.05). None of the defects achieved complete defect closure. Increased new bone formation with HBO or EGCG/BMP-2 was evident in histologic evaluation, but it did not reach statistical significance in histometric analysis. A synergic effect between HBO and EGCG/BMP-2 was not found. Conclusions: Within the limitations of this study, the present findings indicate that adjunctive HBO and EGCG/BMP-2 could be beneficial for new bone formation in rat calvarial defects.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.4
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• pp.25-31
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• 2015

PURPOSE: Previous studies have shown that healthy young adults reduced gait velocity during texting or talking while walking. It was reported that increasing number of pedestrian accidents were related to distract the environmental attention. The purpose of this study was to compare the effects of texting and texting while listening to music on gait parameters. METHODS: Texting and listening to music while walking were assessed in two dual-task condition using 35 healthy young adults. The outcome measurements were assessed in terms of spatiotemporal gait parameters in three walking conditions, namely, comfortable walking speed, walking while texting, and walking while texting and listening to music. To avoid learning effect, subjects were individually blinded to assessment schedule and space. The changes between the three walking conditions were analyzed using repeated measures ANOVA. RESULTS: When comparing the two dual-task conditions with the single-task condition, it was found that dual-task interference was increased in almost gait velocity, cadence, stride length, step time, double limb support, and single limb support. In addition, walking while texting and listening to music condition negatively was affected gait speed, stride length, and step time more than the texting only condition. CONCLUSION: Walking while texting and listening to music as well as waling while texting may decrease pedestrian safety when crossing streets by diverting the person's attention away from the street environment.

• Korean Journal of Agricultural Science
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• v.50 no.4
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• pp.735-747
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• 2023

This study was conducted to identify the appropriate space requirements for forest healing program for physical and mental health care of female cancer survivors in their 40s and 60s. From September to November 2023, 12 cancer survivors were surveyed at Chungnam National University Forest and Daejeon Healing Forest. One Forest Therapy instructor and two researchers conducted a forest healing program once a week for eight sessions of two hours each, Perceptions and satisfaction with the program and space were assessed using pre and post program questionnaires, and the effect of participation in the forest healing program on mood status was evaluated. The satisfaction survey results were supplemented by qualitative studies conducted through post-interviews. Result of the analysis showed that the satisfaction of the participants was very high (4.8/5.0). There was a notable increase in vigor and a decrease in total mood disturbance after participation in the program. Toilets and water facilities (11), tool boxes (9), pest control facilities (3), deck facilities (3), forest hut (3), electrical outlets (2), shade shelters (2), and shoe hairy (1) were proposed as required facilities for cancer survivors. This study demonstrated that the forest healing program is effective in reducing distress in female cancer survivors in their 40s and 60s and appropriate facility standards for the forest healing space are needed to increase the satisfaction of cancer survivors.

• The Journal of Korean Society for Radiation Therapy
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• v.15 no.1
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• pp.11-18
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• 2003

The concrete is usually used to build a radiation therapy facility and the enough concrete thickness for high energy x-ray beam is about 1 meter. But if the space is not enough to build a radiation therapy facility with concrete, the substitute for concrete is needed, and the Ledite can be a good substitute for concrete. In this study, we compared the Ledite with the concrete. The comparing list are the needed shielding thickness, the period of construction and the cost.

• Journal of the Korean Society of Radiology
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• v.15 no.5
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• pp.723-730
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• 2021

This study tries to compare dose distribution between arc radiation therapy and Tomotherapy, which are main radiation therapy modalities. The subjects of this study are lung cancer patients. For planning target volume (PTV), a dose of 60.0 Gy was set as a basis. The PTVmean of Arc was 61.04 Gy, and that of Tomotherapy was 58.50 Gy. The total lung capacities of Arc and Tomotherapy were 3.0 Gy and 4.24 Gy, respectively. The mean heart doses of Arc and Tomotherapy were 0.13 and 0.34, respectively; the mean trachea dose of Arc and Tomotherapy were 1.35 and 2.58, respectively; the mean esophagus dose of Arc and Tomotherapy were 0.41 and 0.86, respectively; the mean spinal cord dose of Arc and Tomotherapy were 3.65 and 4.68, respectively. With regard to the appropriateness of therapeutic effect in DHV, both modalities seemed appropriate. Tomotherapy protected normal tissues better than Arc radiation therapy. In Tomotherapy, patients need to have treatment long in a limited space. If such a point is overcome, Tomotherapy is better. Otherwise, Arc radiation therapy can be applied. This study was conducted with treatment planning images. Therefore, the results of this study are different from actual treatment results. If more research is conducted to overcome the limitation, the effects of radiation therapy are expected to increase further.