• Microbiology and Biotechnology Letters
• /
• v.39 no.4
• /
• pp.364-373
• /
• 2011

Human embryonic stem cells have been highlighted as a valuable cellular source in the regenerative medicine field, due to their pluripotency. However, there is the challenge of the establishment of specific functional cell type forms of undifferentiated human embryonic stem cells (hESC). To establish and purify functional cell types from hESCs, we differentiated undifferentiated hESCs into vascular lineage cells and sorted the specific cell population from the whole cell population, depending on their cell volume, and compared them with the non-sorted cell population. We observed that about 10% of the PECAM positive population existed in the VEGF induced differentiating human embryoid body (hEB), and differentiated hEBs were made into single cells for cell transplantation. After making single cells, we performed cell sorting using a fluorescence-activated cell sorter (FACs), according to their cell volume on the basis of FSC region gating, and compared their therapeutic capacity with the non-sorted cell population through cell transplantation into hindlimb ischemic disease model mice. 4 Weeks after cell transplantation, the recovery rate of blood perfusion reached 54% and 17% in the FSC regions of sorted cells- and non-sorted cells, respectively. This result suggests that derivation of a functional cell population from hESCs can be performed through cell sorting on the basis of cell volume after preliminary differentiation induction. This approach may then greatly contribute to overcoming the limitations of marker sorting.

• Fashion & Textile Research Journal
• /
• v.13 no.6
• /
• pp.900-908
• /
• 2011

The volume of the functional clothing market is gradually growing in Korea. This study intended to identify the relationship among benefits sought in clothing, well-being health consciousness, age, and purchase intention of functional clothing. A survey data was collected from 380 male ranging from 20 to 59 years old and was analyzed SPSS 17.0. As a result, six clothing benefit factors were identified and labeled as attraction improvement, social position, figure flaw compensation, individuality, comfort, and economy. The influences of benefits sought in clothing on the purchase intention was found. Also well-being health consciousness and age moderated the effects of benefits sought in clothing on the purchase intention.

• The Korean Journal of Nuclear Medicine
• /
• v.28 no.1
• /
• pp.52-61
• /
• 1994

Background : The demand for refinement in noninvasive and quantitative assessment of left ventricular (LV) function is increasing. Purpose : To assess normal values of left ventricular functional parameters during both systole and diastole by scintigraphic method using computerized triple-head gamma camera and to evaluate correlations between these parameters. Methods : ECG gated blood pool scan with $^{99m}Tc$-Human serum albumin was performed in 94 normal Korean subjects. Ejection fraction (EF), systolic parameters [peak emptying rate (PER), average emptying rate (AER), time to peak emptying rate (TPER)], and diastolic parameters [peak filling rate (PFR), average filling rate (AFR), time to peak filling rate (TPFR)] were obtained by analysis of LV time-activity curve, the correlation of these parameters to the age and sex, and the correlation between these parameters were evaluated. Results : 1) Mean value of ejection fraction in study subjects was $59.6{\pm}5.25%$ and showed no significant correlation to age (r=-0.08) and sex but showed most pronounced correlation to PFR (r=0.46, p<0.001), PER (r=0.41, p<0.001), AFR (r=0.34, p<0.001) and AER (r=0.28, p<0.01). 2) Mean values of systolic parameters were as follows: $PER=3.22{\pm}0.50$ end-diastolic volume/sec, $AER=2.22{\pm}0.45$ end-diastolic volume/sec, $TPER=103.5{\pm}29.30$ msec. They showed no significant correlation to age and sex. 3) Mean values of diastolic parameters were as follows: $PFR=2.71{\pm}0.51$ end-diastolic volume/sec, $AFR=1.83{\pm}0.44$ end-diastolic volume/sec, $TPFR=132.1{\pm}33.45$ msec. They showed strong correlation to age (r=0.70, -0.64, 0.37, p<0.001). Conclusions : Left ventricular functional parameters in normal Korean subjects were obtained reliably by computerized scintigraphic method and may be applied to the evaluation of cardiac function in diseased patients.

• Culinary science and hospitality research
• /
• v.23 no.8
• /
• pp.1-10
• /
• 2017

This study investigated the quality characteristics of muffins by the amount of addition of suchero (0%, 25%, 50%, 75%, 100%) as there is increasingly higher interest in functional alternative sweetener. The effects of suchero were evaluated in terms of height, volume, weight, specific volume, baking loss rate, colorimeter, and sensory evaluation. Texture and moisture contents of muffins during storage (1, 2, 3 days) were measured. As the ratio of suchero increased, the volume, specific volume, and weight increased, whereas the volume and specific volume was not significant. During storage, moisture content of muffins decreased significantly. The moisture content of the sample containing suchero was higher than S0(control group). The addition of suchero increased L value of crust and crumb decreased, whereas a value and b value increased. The muffin with 100% of suchero (S100) in test group showed the lowest hardness. According to the sensory evaluation, the muffin with 50% of suchero (S50) showed the highest score in terms of appearance, color, flavor, taste, and overall acceptance, S50 showed the best result and the optimum addition of suchero.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.52 no.1
• /
• pp.69-77
• /
• 2010

Research on permeable pavement like asphalt and concrete pavement with porous structure has been increasing due to environmental and functional need such as reduction of run off and flood, and increase and purification of underwater resource. This study was performed to evaluate permeability, strengths and durability of permeable polymer concrete (PPC) using recycled aggregate that is obtained from waste concrete. Also, 6mm length of polypropylene fiber was used to increase toughness and interlocking between aggregate and aggregate surrounded by binder. In the test results, regardless of kinds of aggregates and fiber contents, the compressive strength and permeability coefficient of all types of PPC showed the higher than the criterion of porous concrete that is used in permeable pavement in Korea. Also, strengths of PPC with increase polypropylene fiber volume fraction showed slightly increased tendency due to increase binder with increase of fiber volume fraction. The weight reduction ratios for PPC after 300 cycles of freezing and thawing were in the range of 1.6~3.8 % and 2.2~5.6 %, respectively. The weight change ratio was very low regardless of the fiber volume fraction and aggregates. The weight reduction ratios of PPC with fiber and aggregate were in the range of 1.3~2.7 % and 2.2~3.2 % after 13 weeks and was very low regardless of the fiber volume fraction and aggregates.

• Journal of Life Science
• /
• v.24 no.10
• /
• pp.1125-1131
• /
• 2014

The purpose of this study was to investigate the relationship between quadriceps composition and its functional contractility in obese and nonobese elderly individuals. Thirty-four ($70{\pm}2yr$) individuals (obese, n=21; nonobese, n=13) participated in the study. The thigh composition was assessed with a CT scan, and its functional contractility was measured with an isotonic dynamometer. Variables were analyzed with a $2{\times}2$ two-way ANOVA and a contrast test (p<0.05). There were no between-group differences in the subjects' ages and heights, but individuals in the obese group were approximately 23% heavier and had 18% more fat than those in the nonobese group, regardless of gender. The total thigh volume of the obese elderly was greater (~29%) than that of the nonobese elderly, regardless of gender, and the fat volume (~39%) of the obese elderly was greater than that of the nonobese elderly, regardless of gender (p<0.05). Interestingly, the obese elderly tended to have a greater thigh muscle volume (~17% for males [p<0.05] and ~10% for females) than the nonobese. Despite the greater muscle volume, the peak knee extensor torque of the two groups was comparable or slightly greater in the obese individuals. However, when this was normalized by the total thigh volume, the nonobese males showed significantly greater peak torque (~26% for right and ~20% for left; p<0.05) compared to the obese males. The nonobese females also showed greater peak torque (~8% for both legs) than the obese females after normalization, but the result was not statistically significant. In conclusion, although the obese elderly individuals had greater quadriceps muscle mass than the nonobese, the normalized peak torque of the obese was significantly lower than that of the nonobese, implying a lower degree of muscle contractility.

• Journal of the Korean Society of Costume
• /
• v.60 no.9
• /
• pp.150-161
• /
• 2010

In Korea, recent trends indicate an increase in the volume of the functional clothing market. This study investigated the evaluative criteria and information sources of functional clothing according to gender and age. A total of 756 responses were analyzed using descriptive statistics, MANOVA, and Duncan's test. The main effect of gender on the evaluative criteria and information sources of functional clothing was identified. Compared with male consumers, female consumers gave more importance to price and aesthetic criteria. Female consumers take advice from colleagues and companions, as well as use information obtained from mass media to a greater extent than male consumers. Age was seen to have an effect on evaluative criteria and information sources in purchasing functional clothing. Respondents in their forties and fifties took textile quality and durability more seriously. Information available on the Internet and following the dressing styles of celebrities were preferred by respondents in their twenties.

• Archives of Plastic Surgery
• /
• v.37 no.5
• /
• pp.607-612
• /
• 2010

Purpose: Maxillectomy for malignant tumor resection often leads to functional and aesthetic sequalae. Reconstruction following maxillectomy has been a challenging problem in the field of head and neck cancer surgery. In this article, we described three dimensional midface reconstructions using free flaps and their functional and aesthetic outcomes. Methods: We reconstructed 35 cases of maxillectomy defects using 9 radial forearm free flaps, 7 lattisimus dorsi musculocutaneous free flaps, 6 rectus abdominis musculocutaneous free flaps, 4 fibular osteocutaneous free flaps, and 9 anterolateral thigh free flaps, respectively. We classified post-maxillectomy defects by Brown's classification. 1 Articulation clarity was measured with picture consonant articulation test. Swallowing function was evaluated with the University of Washington quality-of-life Head and Neck questionnaire by 4 steps.2 Aesthetic outcomes were checked to compare preoperative with postoperative full face photographs by 5 medical doctors who did not involve in our operation. Results: The average articulation clarity was 92.4% (100-41.9%). 27 (81.9%) patients were able to eat an unrestricted diet. Aesthetic results were considered excellent in 18 patients (51.4%). Functional results were best in the group reconstructed with fibular osteocutaneous free flap. Considering the range of wide excision, aesthetic results is best in the group reconstructed with anterolateral thigh free flap. Conclusion: The free flap is a useful technique for the reconstruction of the midface leading to good results, both functionally and aesthetically. Especially, because osteocutaneous flap such as fibular osteocutaneous free flap offered bone source for osteointegrated implant, It produces the best functional results. And perforator flap like as anterolateral thigh free flap reliably provides the best aesthetic results, because it provides sufficient volume and has no postoperative volume diminution.

• Journal of Korean Biological Nursing Science
• /
• v.23 no.3
• /
• pp.159-169
• /
• 2021

Purpose: The purpose of this study was to analyze research trends and find whether Post-Traumatic Stress Disorder (PTSD) of refugees could affect structural or functional changes of brains of those under MRI, focusing on volumes, functional connectivities, and metabolites. Methods: A literature search was done using PubMed, Embase, RISS, and KMBase to identify studies that matched our research purpose. A total of eight studies were identified using Prisma flow diagram by two reviewers independently. Results: Eight studies were identified. Three studies were on North Korean defectors as subjects. The number of studies that observed structural changes, functional changes, and metabolite changes in brains was 2, 5, and 2, respectively. Although each study observed various parts of the brain, anterior cingulate cortex (ACC) was observed commonly in three studies. The PTSD group showed reduction of ACC volume and N-acetyl-aspartate (NAA) metabolite in ACC compared to the non- PTSD group. When exposed to negative stimuli, the PTSD group showed higher neural activity than the non-PTSD group, but not vice versa. Conclusion: ACC showed significant difference in volume, neural activity, and NAA metabolite between the PTSD and the non-PTSD group, resulting in significant differences in structural changes, functional changes, metabolite changes, respectively. This study showed the need for conducting more research using various biomarkers to clarify the relationship between PTSD of refugees and their brain changes.

• Tuberculosis and Respiratory Diseases
• /
• v.51 no.3
• /
• pp.270-274
• /
• 2001

A functional upper airway obstruction due to a vocal cord dysfunction(VCD) is characterized by a paradoxical adduction of the vocal cords throughout the respiratory cycle with no obvious organic cause for the obstruction. It commonly occurs paroxysmally and imitates acute asthmatic attacks, often in patients with coexisting asthma. They present with episodes of dyspnea associated with inspiratory wheezing that persists despite conventional asthma treatment and a flattening of the inspiratory limb of the flow-volume curve ; an adduction of the vocal cord during inspiration. Failure to recognize concurrent vocal cord dysfunction and asthma has led not only to the excessive use of bronchodilators and corticosteroids, but also to intubation and tracheostomy. Here, we report a case of coexistent obstructive pulmonary disease and functional upper airway obstruction due to a vocal cord dysfunction where a bronchoscopy showed a paradoxical vocal cord motion and typical features of a variable extrathoracic obstruction and a lower airway obstruction on the Flow-volume loop during a symptomatic period.