• 대한한방부인과학회지
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• 제24권4호
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• pp.186-193
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• 2011

Purpose: This study was performed to find correlations between Edema Index and Heart Rate Variability(HRV) conducted in early postpartum period. Methods: 17 postpartum women were participated in this study which was conducted with Inbody 720(Biospace Co. Ltd.) and SA-6000(Medicore Co. Ltd.). Edema Index(Extra Cellular Water/Total Body Water) was calculated after body composition analysis and HRV result(TP, VLF, LF, HF, HF norm, LF norm, LF/HF ratio) was analysed within a week after delivery. Results: There was no significant correlations between Edema Index and HRV results in time domain analysis. also Edema Index and TP, LF, HF, LF/HF ratio have no significant correlations in frequency domain analysis. but only VLF data has significance compared with Edema Index. Conclusions: It can be suggested that VLF results analysed by HRV can be useful reference estimating postpartum edema especially occurs in early postpartum period.

• 대한후두음성언어의학회지
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• 제7권1호
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• pp.11-19
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• 1996

Reinke's edema is used for describing varying degrees of chronic swelling of the vocal folds. The acoustic analysis of Reinke's edema has not been reported so far in this country. The purpose of this study is to clarify acoustic and aerodynamic characteristics of the Reinke's edema. Several acoustic evaluations ＆ aerodynamic studies were done in 20 Reinke's edema patients and the data was compared with those of 20 normal controls. Videolaryngoscopy also was done to classify the severity in grading. We used C-Speech, Doctor speech science, and Phonatory function analyser. In C-Speech, we compared jitter, shimmer, and SNR(signal to noise ratio) of normal and Rrinke's edema patient. In Doctor speech science, we compared NNE(Glottal noise energy), speech fundamental frequency, voice quality between two groups. And in phonatory function analyser for aerodynamic function test, we compared speech intensity, airflow rate, and expiratory pressure between two groups. In conclusion, Reinke's edema patients showed lower voice pitches than normal, additionally jitter, shimmer, SNR(signal to noise ratio), NNE(Glottal noise energy), airflow rate, and expiratory pressure may be meaningful parameters for diagnosis and prognosis for treatment.

• 약학회지
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• 제26권2호
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• pp.97-103
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• 1982

This paper presents anti-inflammatory effects of nonsteroidal anti-inflammatory drugs and their copper complexes, and the change of content of copper in serum, liver, brain and edema foot induced by 1% carrageenan in rats, and also investigation of stomach hemorrhage. The results were as follows. 1. The content of copper decreased in liver and brain, however, the concentration of copper significantly increased in serum and edema site after carrageenan injection in rats. 2. The content of copper in serum and edema site was decreased after administration of anti-inflammatory drugs. 3. Edema inhibition rate of aspirin was, higher than that of copper (II) aspirinate, but edema inhibition rate of copper complex of naproxen was markedly higher than that of naproxen. 4. Hemorrhage of stomach of copper salicylate was higher than that of sodium salicylate, but hemorrhage of stomach of sodium naproxen was higher than that of copper naproxen.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.137-139
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• 2001

The authors report a 42-year-old woman presented with a falx meningioma with disproportionately severe peritumoral edema. Histological examination including immunohistochemical staining resulted in the diagnosis of secretory meningioma. In addition to tumor size, edema could not be explained by location, growth rate, vascular involvement, or other factors. We conclude that secretory meningiomas may possess an innate ability to cause brain edema.

• 대한임상독성학회지
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• 제8권2호
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• pp.113-121
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• 2010

Purpose: Drug-induced non-cardiogenic pulmonary edema has been reported on in a drug case series. For most of the agents that cause pulmonary edema, the pathogenic mechanisms that are responsible for the pulmonary edema remain unknown. We report here on the cases of suspected drug-induced pulmonary edema and we analyze the clinical characteristics. Methods: We reviewed the medical records of 1,345 patients who had drug adverse effects and drug poisoning from January 2005 to July 2010, and 480 of these patients were admitted to the EM Department. Among them, 17 patients developed abnormal chest radiological findings and they were analyzed for any clinical characteristics, the initial symptoms, securing the airway and the clinical results. Results: Seventeen patients out of 480 (3.54%) developed drug-induced abnormal chest radiographic pulmonary edema; they displayed initial symptoms that included mental change (41.2%), dyspnea (17.6%), vomiting (11.8%), etc, and some displayed no symptoms at all (11.8%). Only 3 patients out of the 11 who died or had severe pulmonary edema were able to obtain an advanced airway prior to their arrival to the EM Department. Clinical recovery was generally rapid and this was mostly completed within 6 hours. The mortality rate was 11.8% (2 of 17 patients), and the causative drugs were found to be propofol (35.3%, 6 of 17 patients), multiple drugs (41.2% or 7 out of 17) and one patient each with ephedrine, ethylene glycol, doxylamine and an unknown drug, respectively. Conclusion: Drug-induced pulmonary edema and deaths are not uncommon, and recovery is typically rapid with few long-term sequelae when drug administration is discontinued. Oxygen therapy and securing the airway must be performed during transportation for patients with pulmonary edema.

• 동의생리병리학회지
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• 제18권2호
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• pp.446-450
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• 2004

Objectives: In order to study the effects of Harpagophyti Radix in rats with arthritis induced by Freund's complete adjuvant. Methods : In this study, rats with arthritis induced by Freund's complete adjuvant were divided into four groups; Normal, Control, Sample A(Harpagophyti Radix 6mg/200g) and Sample B(Harpagophyti Radix 12mg/200g). After 1 week, separated searches were made on the change of edema rate, the count of WBC, the quantity of total protein, total bilirubin, GOT and GPT in the serum. Results: In the right plantar edema, both of Sample groups showed a decrease in comparison with Control group. In the count of WBC, the quantity of serum total protein and SGOT, Sample B showed a decrease with statistical significance in comparison with Control group. In the quantity of serum total bilirubin and SGPT, both of Sample groups did not show any harmful change in in comparison with Control group. Conclusion : Reviewing these experimental results, it appeared that Harpagophyti Radix showed the therapeutic effect of anti-inflammatation on adjuvant arthritis.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권3호
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• pp.227-231
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• 2022

Although rare, complications can occur with anesthetic procedures. The posterior superior alveolar nerve (PSAN) block anesthetic technique has a high success rate, but positive aspiration can cause bruising, transient diplopia, blurred vision, and temporary blindness in approximately 3% cases. When edema occurs, it is occasionally massive, especially in the infratemporal fossa, and the resulting hematoma is usually unsightly. A 20-year-old woman presented with massive edema followed by hematoma in the upper right jaw immediately after PSAN block administration, which subsequently spread to the oral mucosa. The patient did not report any complications during the anesthetic procedure. However, after the injection was administered, the patient experienced anesthetic sensations, which rapidly evolved to facial edema. There was mild pain, but without intraoral or extraoral bleeding. The patient was prescribed medicines and instructed to perform contrast therapy. Although hematomas and edema are rare, they are difficult to prevent. The choice of local anesthetic and appropriate application of the anesthetic technique can minimize their occurrence.

• 동국한의학연구소논문집
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• 제2권1호
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• pp.155-166
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• 1993

Geukhachukeutang is used to cure blood stasis in Oriental Medicine. In order to investigate medical value on intravascula coagulation and contusion blood stasis, the effect of Platelet number, Fibrinogen quantity, Prothrombin time, FOP density, Paw edema increasing rate after prescribing Geukhachukeutang concentration liquid orally were observed. The obtained results are summerized as follows ; 1. Platelet number and Fibrinogen quantity are significantly increased, and Prothrombin time and FOP density are significantly decreased by Geukhachukeutang after inducing intravascula coagulation. 2. Platelet number and Fibrinogen quantity are not significantly increased, and Prothrombin time is not significantly decreased either, by Geukhachukeutang after inducing contusion blood stasis but Paw edema increasing rate is remarkablely decreased in three or four hours of the groups of prescribing. According to the above results, Geukhachukeutang will be used for contusion blood stasis and Intravascula coagulation effectively owing to being accepted as a favorable operation on Platelet number, Fibrinogen quantity, Prothrombin time, FDP density and Paw edema increasing rate.

• Journal of Korean Neurosurgical Society
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• 제38권1호
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• pp.12-15
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• 2005

Objective : Cerebral edema develops in the brain tumors by loosening of the endothelial tight junction. Tight junction[TJ] proteins, such as occludin and claudin bind adjacent cells tightly. Authors examine the expression rate of occludin in human brain tumors to evaluate the effect of altered expression of occludin on cerebral edema. Methods : Seventy surgical specimens stored at $-70^{\circ}C$ were used. It included 14 astrocytic tumors, 27 meningiomas, 12 scwannomas, 7 pituitary adenomas, 6 hemangioblastomas. and 4 craniopharyngiomas. After protein extraction, expression of occludin was investigated by Western blot analysis. The tumors were classified according to World Health Organization[WHO] classification. Results : The expression rates of occludin in brain tumors were : glioma [8/14=57.1%]. meningioma [16/27=59.3%], schwannoma [10/12=83.3%], pituitary adenoma [6/7=85.7%], hemangioblastoma [6/6=100%], and craniopharyngioma [3/4=75.0%]. The expression rate in glioma and meningioma was lower than other brain tumors. In gliomas, high grade tumor [1/4=25.0%] exhibited lower expression rate of occludin than low grade one [7/10=70.0%]. Conclusion : These results suggest that the expression of occludin is different among the various kinds of brain tumors. In gliomas, its expression is correlated with the histological grade. It may indicate that occludin plays a role in the development of edema in the brain tumors.

• 약학회지
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• 제25권3호
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• pp.109-114
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• 1981

The authors investigated drug interaction of ibuprofen and prednisolone in antiinflammatory and antipyretic activities. We have found significant differences of the antiinflammatory and antipyretic activities between single and concurrent administration of ibuprofen and prednisolone, using Sprague-Dawley Strain rats, carrageenin as a phlogistic agent and brewer's yeast as a fever inducing agent. 1) Ibuprofen(20mg/kg) was administered to the rats orally and resulted in significant reduction of (31.70 %) the swelling of rat paw induced by carrageenin, 2) prednisolone (9mg/kg) showed significant reduction of (45.76%) the swelling, 3) concurrent administration of ibuprofen (20mg/kg) and prednisolone (9mg/kg) also reduced (57.40%) the swelling. In ibuprofen (125mg/kg) administration, the inhibition rate of edema was 39.32% and in prednisolone (1mg/kg) administration, the rate was 39.04%. In concurrent administration of ibuprofen (125mg/kg) and prednisolone (1mg/kg), the inhibition rate of edema was 63.09%. Concurrent administration of ibuprofen and prednisolone showed more anti-inflammatory effects than single administration of ibuprofen and prednisolone respectively. Prednisolone itself did not show antipyretic effect, but concurrent administration of ibuprofen and prednisolone showed more antipyretic effects than ibuprofen single administratron.