• 한국콘텐츠학회논문지
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• 제12권8호
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• pp.233-239
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• 2012

본 연구는 본원에서 사용 중인 DR 장비에 내장되어 있는 구리필터를 이용하여 골반전후방향 촬영 시 영상의 화질을 저하시키지 않으면서 환자의 피폭선량을 줄이고자 실시하였다. 동일 조사선량으로 none filter, 0.1mmCu, 0.2mmCu, 0.3mmCu로 변화시켜 선량을 측정하고 PCXMC 프로그램으로 장기선량을 산출하였다. 결과는 고환과 방광에서 높은 선량이 검출 되었으며 필터 두께가 증가할수록 선량이 감소하였고 감소폭은 0.1mmCu 일 때 가장 크게 나타났다. 또한 촬영된 영상을 3명의 영상의학과 전문의에게 의뢰하여 평가해 본 결과 0.1mmCu를 사용한 영상이 none filter시와 가장 동일한 진단적 가치가 있는 영상으로 평가 되었고 이때 골반부 입사표면선량은 0.895mGy로 none filter 대비 47%의 선량을 줄일 수 있었다. 따라서 골반전후방향 촬영 시 0.1mmCu를 사용하여 촬영하면 환자의 피폭선량을 효과적으로 감소시킬 수 있을 것이다.

• 한국운동역학회지
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• 제25권2호
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• pp.231-240
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• 2015

Objective : This study is for providing data about men's functional sport underpants. It provides the fundamental data of biomechanics by measuring and analyzing the functionality of various underpants using infrared thermal image camera. Method : Then author drew a conclusion based on the final analysis of 965 questionnaire survey results about issues on men's functional sport underpants after discarding invalid questionnaires, as following. Change in body temperature while wearing functional underpants compared to general briefs or boxer pants showed lower temperature by approximately 1~2 degrees Celsius. In the case of general underpants, wearer sweats and feels hotter due to the friction of penis, scrotum and thigh. However functional sport functional underpants improved this issue with ergonomic 3D design by putting penis towards the lower part of the abdomen(below the navel) while putting the scrotum comfortably on the testicles, which enables to make room between the penis, scrotum and thigh of a wearer. Results : This was analyzed to lower the temperature of penis and scrotum. The survey results about the quality of functional underpants showed that 78% of the respondents felt comfortable while driving; 68.5% replied that frictional heat decreased while working out; 78.7% felt less sweat and humidity; 81.7% replied as highly wearable and comfortable; 77.1% replied functional sport underpants were the most comfortable in routine lives or in workout times. Putting all such results together, it is possible to conclude that functional sport is an excellent product. Conclusion : This can be evaluated as an excellent functional sport underpants, towards the penis abdomen (under the navel) in 3D human engineering design, by the scrotum to wearing to be easier to scrotum of pocket, the penis and scrotum and thighs were separated and analyzed with a function that will lower the body temperature of the penis and scrotum.

• 한국의상디자인학회지
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• 제18권1호
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• pp.169-181
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• 2016

This study analyzed the characteristics and patterns of men's drawers panties to get basic data for their design. For this, drawers panties in 7 different brands (4: domestic brands, 3: imported brands) in terms of a front-center shape were collected, and the shape of men's drawers panties, characteristics of the materials, dimensions & type of patterns by the part and front-center patterns were analyzed. The study results found the followings: First, in terms of the shape of men's drawers panties, the front-center part were designed to rest the penis and scrotum in a natural and comfortable manner without a pee slit. They were seamless on the sides except for one product with side seams. Second, the drawer panties were made of elastic polyurethane materials. Specifically, domestic brand items used warm, elastic and durable nylon, polyester and rayon and polyurethanes while imported brands were mostly made of absorbent and sanitary polyurethanes. Third, regarding a size of drawer panties by part, imported brands were large in waist circumference. In terms of waist breadth at the front center, there was difference depending on an oval type. In addition, the front length at the front center differed by product, revealing difference in three-dimensional effect at the front center. The side length also differed greatly by product, which means that there might be a great difference in wear comfort. Fourth, in terms of the patterns of men's drawers panties, there was difference in side seams, center back seam and front-center patterns. Among a total of 7 products, only one product had side seams, and center back seams were found in two products only. Fifth, in terms of front-center patterns, the drawer panties can be divided into three types, creating three-dimensional effect not to give any pressure on the crotch: i) the cutting line only at the bottom of the front center part where the penis is rested, ii) puff created at the front center by adding a transverse line to the center line, iii) cutting transverse line to separate the penis from the testicles.

• 셀메드
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• 제2권3호
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• pp.26.1-26.5
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• 2012

Adverse side-effects and lack of scientific validation of some chemotherapeutic agents prevent the use of many traditional medicines claimed to have anti-cancer effects. Ethanolic extract of Conium maculatum has long been used in traditional and alternative systems of medicine including homeopathy for the treatment of glandular enlargements, cancerous tumours or hard lumps of testicles, prostate, ovaries, breasts and/ or uterus, particularly in the breast. However, if and how it acts still remains scientifically unknown. This study aims to test if Conium extract (CE), used as mother tincture of Conium in homeopathy, has demonstrable anti-cancer potentials without having much cytotoxicity in normal cells. Cytotoxicity of the drug was tested by conducting MTT assay on both normal (peripheral blood mononuclear cells) and HeLa cells. We also evaluated DNA fragmentation and DNA damage by DAPI and diphenylamine assay. The LDH activity assay was done to evaluate the percentages of apoptosis and necrosis. ROS accumulation also was evaluated to pin-point the actual events of apoptosis. Administration of drug clearly demonstrated its anti-cancer potentials as evidenced by the DNA damage analysis. The ROS activity also increased in case of the CE treated cells. LDH data revealed that the mode of cell death was mainly apoptotic and not necrotic. CE appears to induce apoptosis of cancer cells through ROS mediated pathway, and has negligible cytotoxicity against normal cells.

• Asian-Australasian Journal of Animal Sciences
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• 제16권5호
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• pp.706-713
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• 2003

Two experiments were conducted to evaluate the efficacy of dietary FERMKIT, a commercial toxin binder consisting of probiotic-fermented natural product containing chitin, chitosan and chitosan oligosaccharides ($FERMKITO^{(R)}$, EASY-BIO SYSTEM, Inc., Korea), in binding aflatoxin (AF) and zearalenone (ZEN) and ameliorating their mycotoxicity in meat type ducks. FERMKIT was supplemented to AF contaminated diets (at 120 ppb) at either 0.3 or 0.6% in experiment 1 and to ZEN contaminated diets (at 150 ppb) at 0.6% in experiment 2. In experiment 1 body weight gains were reduced by 37% and mortality was increased by 18% in ducks fed diet contaminated with AF at 120 ppb compared to ducks fed control diet (<10 ppb AF) for the 4-wk experimental period. However, dietary FERMKIT supplementation effectively alleviated overall toxicity induced by AF. The significant treatment-related changes in feather growth, web-toe hemorrhage, leg deformity, liver paleness, organ weights, hematological values and serum biochemical values, as compared to the control, were observed. The FERMKIT supplementation significantly diminished the adverse effects of AF and restored all the parameters measured back (<0.05) toward the control values. These findings indicated that FERMKIT, when added at the levels of 0.3 or 0.6% in the 120 ppb AF diets, could modulate the toxicity of AF with percentage sorption capacity of 52.70% at the level 0.3% and 79.85% at the level 0.6% of the diets (experiment 1). In experiment 2, FERMKIT, when added at 0.6% to the 150 ppb ZEN diets for the 4-wk experimental period, diminished the toxicity as shown by body weight gain, weights of testicles, oviducts, Bursa of Fabricius and cloaca eversion score as compared with the controls (<10 ppb ZEN) and 150 ppb ZEN diet with no added FERMKIT. The findings indicated that FERMKIT could be protective against the effects of ZEN in young growing ducks with percentage sorption capacity of 67.11% as evaluated from toxicity index parameter measured when added at 0.6% of the diets containing 150 ppb ZEN.

• 디지털융복합연구
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• 제12권6호
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• pp.433-438
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• 2014

본 연구는 흰쥐의 정소에 방사선을 조사하였을 때 시간이 경과함에 따라 나타나는 정소세포 및 정자의 변화를 현미경학적으로 얻은 영상을 기초로 영상처리에 의한 정량분석을 통하여 정자의 변화에 대한 결과를 정량화함으로써 더 정확하고 객관적인 결과를 얻고자 하는데 그 목적을 두고 있다. 연구에는 8주 수령의 흰쥐를 대상으로 하였으며, 6 MV의 X선을 1회 2 Gy를 전신 조사하였다. 총 30 마리의 흰쥐를 대상으로 방사선을 조사하지 않은 정상대조군과 실험군을 조사 즉시, 조사 2시간, 4시간, 8시간, 24시간 후에 각 실험군 마다 5마리의 정소를 각각 적출하였다. 적출 후 Periodic acid Schiff 염색을 시행하여 정상대조군과 실험군에서의 정소세포와 정자의 상태를 관찰하였다. 방사선조사 후 24시간까지, 정소세포수와 정자수가 점차 감소하는 것을 정성적 및 정량적으로 유의함을 확인하였다.

• 한국의학물리학회지:의학물리
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• 제19권3호
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• pp.172-177
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• 2008

정량적인 방사선치료 선량을 예측하기위한 일환으로 한국표준남성에 기초하여 수학적 모의피폭체를 제작하였다. 이후 전립선을 선원장기로 하여 전립선암 근접치료 시 발생할 것으로 예상되는 전립선 및 주변장기의 흡수선량을 산정하였다. 모의모사를 위하여 방사성핵종은 전립선 근접치료에 유용하게 사용되는 $^{25}I$ 및 $^{103}Pd$선정하였고, 초기 방사능을 1 Ci를 투여하는 것으로 가정하였다. 그 결과 선원장기인 전립선이 $^{125}I$ 및 $^{103}Pd$ 경우 각각 101 Gy/Ci와 7.24 Gy/Ci를 나타냈으며, 전립선을 제외하고 흡수선량이 높은 장기는 비교적 전립선과 인접되어 있는 장기 즉 음경과 음낭, S자결장, 정소, 방광순으로 나타났다.

• Asian-Australasian Journal of Animal Sciences
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• 제5권1호
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• pp.63-67
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• 1992

This paper reports the effects of rare earth nitrate (REN) on the growth of internal organs and mineral elements in serums of broiler chickens. The REN used is mixture of light RE containing mainly La, Ce, Pr and Nd 4 elements. 40 eight-week old AA broiler chickens were divided randomly into four groups that their treatments were respectively 0, 20, 200 and 2000 mg REN/kg feed and the duration of the experiment was 60 days. Responses were measured in terms of internal organic weight and tissue, contents of mineral elements in serums. There were no significant differences between the organ ratios and tissue changes of the 20, 200 mg REN/kg groups and the control group. The organs included the heart, liver, kidneys, lungs, testicles, thyroids, adrenal glands, pancreas, tonsies of caecum, stomachus glandularis, duodenum, ileum and bursa of Fabricius. The liver and thyroid indices of 2000 mg REN/kg group were significantly higher than those of the control group (p < 0.01, p < 0.05) and the adrenal gland index lower (p < 0.05). The pathlolgic changes in the heart, kidney and thyroid were more serious than that of the control group. No significant differences occurred between the contents of K, Na, Mg elements in the serum of all groups, with the exception of the content of Ca, which was higher in the 2000 mg/kg group (p < 0.05). The contents of all trace elements including Mn, Zn and Cu, but except Fe, in the serums of all the treated groups were significantly higher than those of the control group (p < 0.01).

• 한국임상수의학회지
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• 제26권2호
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• pp.185-188
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• 2009

6개월령의 보스톤 테리어가 미측 음경 돌출과 불완전 형성된 포피, 이분화된 음낭, 잠복고환과 음경골 이형성을 나타내었다. 신체검사상, 요도구멍은 회음부 표면에 위치하였고 섬유성 띠는 귀두로부터 회음부에 있는 요도구멍까지 연결되어 있었다. 또한, 잘못 위치한 요도구멍을 통한 상행성 감염에 의하여 요도염을 나타내었다. 교정수술은 외부생식기 전체와 잠복고환을 절제하기 위하여 시행되었다. 포피, 음경 그리고 잠복고환은 성공적으로 절제되었다. 수술 후 요도구멍을 주기적으로 세척하고 항생제를 투여한 이후, 재발성 요도염은 사라졌다. 만약, 요도구멍의 위치가 재발성 요도염의 원인과 요실금의 주요 원인이 아니라면, 요도구멍을 재형성할 필요가 없는 이 치료법을 이용할 것을 제안한다.

• 한국동물위생학회지
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• 제36권4호
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• pp.227-232
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• 2013

The dried root of Angelica gigas (A. gigas) has been traditionally used as an oriental medicine, which is known to improve blood circulation and blood stasis. In the present study, leaves and stalks of A. gigas were used to investigate their effects on the innate immunity. The extracts were prepared from leaves and stalks of A. gigas and were fed to mice. The numbers of blood cells, total WBCs, neutrophils, lymphocytes, eosinophils and basophils were increased by 50% in mice fed with leaves extract of A. gigas compared to control mice. However, the numbers of blood cells were decreased when treated with stalks extract of A. gigas. The level of cholesterol and triglyceride in serum was markedly reduced in both mice group fed with leaves extract and stalks extract of A. gigas compared to control group (P<0.01). There was no significant change in the level of albumin, total protein, phosphate and calcium in serum. Activity of cationic peptide was found to be diffused in the testicles of mice fed with leaves extract of A. gigas compared to control group, which might be due to increased lysozyme in testicle. The lysoplate assay and immunohistochemistry assay suggest that the extract of leaves and stalks of A. gigas are immunogenic, but the effects might be related with acquired immune response rather than innate immunity.