• Title/Summary/Keyword: terminal density

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Morphological Changes in the Mammary Organ Culture of the Rat Treated with 7,12-Dimethylbenz[$\alpha$]anthracene and N-methyl-N-nitrosourea (7,12-Dimethylbenz[$\alpha$anthracene 및 N-methyl-N-nitrosourea를 투여한 랫드 유선 조직 배양에 대한 형태학적 변화)

  • 문지영;정자영;김옥희;이형환
    • Toxicological Research
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    • v.16 no.4
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    • pp.275-284
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    • 2000
  • The organ culture model of the whole mammary gland has many advantages for the study of branching morphogenesis and biological characteristics, including tumorigenesis. Prior to whole gland organ culture, rats were treated with 7,12-dimethylbenz[a]anthracene (DMBA) or N-methyl-N-nitrosourea (MNU) for one week. The tramdorming effect and the morphological changes were assessed by the whole mount preparations and histopathological examination in terminal end buds (TEB), terminal ducts (TD), alveolar buds (AB), alveolar lobules (AL) and hyperplastic alveolar nodules (HAN) of the mammary gland. Grossfindings of the mammary glands at dissection were higher branching morphogenesis and larger volume in carcinogen-treated groups than in carcinogen-non-treated groups. Results of the whole mount method were coincided with those of the histopathological observations. Circular TEB, normally maintained AB, AL, and high cellular density were more frequently observed in carcinogen-treated groups than in carcinogen-nan-treated groups. Histopathologically, as a preneoplastic marker, HAN was maintained only in mammary organ culture of the carcinogen-treated groups. These findings suggest that in vivo trans-formation effects by carcinogens persisted during the mammary organ culture. These results were more characteristic in DMBA than in MNU-treated group. Ducts and terminal ducts appeared to have lost morphology during their growths in case of without diethylstilbestrol (DES). The fact that in vitro organ culture without DES was resulted in abnormal ductular morphogenesis confirms that DES is a physiological regulator of ductular epithelial cell growth.

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Pb, Cu, Zn Contaminants and Their Correlation of Soil, Leave and Bark of Ginkgo. B and Ambient Air Adjacent to a Heavy Traffic Road Side (교통량 과밀 도로주변의 토양과 가로수, 대기중 Pb, Cu, Zn 중금속 농도와 그 상관성에 관한 연구)

  • 박기학
    • Journal of Environmental Health Sciences
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    • v.18 no.2
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    • pp.19-25
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    • 1992
  • The study was carried out to investigate the correlation between the heavy metals emitted by the motor vehicles with the heavy traffic road side environment (soil, leave, bark, ambient air). The Pb, Cu, Zn contents in road side soil sand leaves, barks from Ginkgo, biloba and ambient air adjacent to the heavy traffic road side from June to August, 1992 Suwon city were analyzed by Atomic absorption spectrometry and Inductively coupled plasma emission spectrophotometry. The results were as follows: 1) The high levels of heavy metals concentration were Pb, at city-terminal in soil (186 $\mu$g/g), Cu, at city-terminal in soil (221 $\mu$g/g), Zn, at city-terminal in ambient air (252 $\mu$g/m$^{3}$). 2) The low leves of heavy metals concentration were Pb, at North-gate in ambient air (1.65$\mu$g/m$^{3}$), Cu, at North-gate in ambient air (4 $\mu$g/m$^{3}$), Zn, at North-gate in ambient air (15.31$\mu$g/m$^{3}$). 3) The regional distribution of Pb, Cu, Zn in road side soils, leaves and barks from Ginkgo, biloba, ambient air show high levels in turn, city4erminal, Guan Sean Dong, South gate, North gate. 4) The concentration of heavy metals (Pb, Cu, Zn) in soils, leaves, barks, ambient air was highly correlated with the traffic volume of the sampling sites (r=0.64~0.96). To conclude that the high levels of Pb, Cu, Zn contaminations were positively related to motor vehicles-borne pollutants and road side soils, trees, ambient air adjacent to a high density building area with low road coverage and heavy traffic volume were reflected strongly by the hazardous pollutants emitted by motor vehicles.

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Analysis of Channel Characteristics at Around 20 GHz for Satellite On-The-Move Terminal (이동형 위성단말을 위한 20 GHz 대역 채널 특성 분석)

  • Kwon, Kun-Sup;Heo, Jong-Wan;Hwang, Ki-Min;Lim, Chul-Min;Ryu, Heung-Gyoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.2
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    • pp.223-234
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    • 2014
  • This paper describes the analysis results of channel characteristics in the operating area of satellite OTM(On-The-Move) terminal. The communication channel between the Koreasat-5 and OTM terminal on a test car is measured and recorded from Daejeon to Daecheon, using the downlink frequency of around 20 GHz. And the measurement data are divided into two classes ; highway environment and national road environment, and then are statistically analyzed. The statistical evaluation of satellite channel is conducted by using probability density function and Markov model and then presents average connection duration(ACD), average fade duration( AFD), and level crossing rate(LCR) of highway environment and national road environment. Finally the statistics data of the two environments are compared with each other.

A New Over-the-Cell Routing System (새로운 Over-the-Cell 배선시스템)

  • Lee, Seung-Ho;Chong, Jong-Wha
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.11
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    • pp.135-143
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    • 1990
  • A new over-the-cell routing system is proposed in this paper. The proposed system efficiently reduces not only the channel density but also the routing density in cell region. Generally, the over-the-cell system consists of three phases. Namely, over-the-cell routing, terminal selection and channel routing. In this paper, to select the nets to be routed over the cells, weights are assigned on the intersection graph considering both the channel density and the intersection relations among other nets. When selected nets are blocked by feedthroughs or metal layers for internal logic, they are routed by maze algorithm. Also, in order to reduce channel density, the terminals to be routed in a channel are selected using the minimum weight spanning tree. Channel routing is carried out with a channel router of HAN-LACAD_G. The effectiveness of the over-the-cell routing system is shown by the experiments with benchmark data and its application to the gate array layout system.

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A Study on the Measurement of Physical Properties for Miscellaneous Cereal Crops Sorting (잡곡 선별을 위한 물성 측정에 관한 연구)

  • Kim, Hoon;Lee, Hyo-Jai;Han, Jae Woong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.354-360
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    • 2020
  • This study examined the factors for sorting miscellaneous cereal crops using a rice-sorting device by analyzing the physical characteristics according to the moisture content. The initial moisture contents of miscellaneous cereal were 16.3, 19.8, and 16.5%, respectively. The samples were used in the experiment after drying to five levels. The width, length, and area of the samples increased with increasing moisture content except for the roundness, and all the prediction models were developed with a first-order linear equation. The bulk density of Italian millet and sorghum increased with increasing moisture content, whereas the bulk density of common millet was unaffected by the change in moisture content. The terminal velocity of the samples increased with increasing moisture content, and a first-order linear equation was used to develop the prediction models. The measured physical properties of the miscellaneous cereal crops based on the changes in the moisture content could be expressed using a first-order experimental model equation. Therefore, the rice-sorting device could be applied to the terminal velocity, but the other device applying the geometrical characteristics and bulk density was required to change the design of the process depending on the type of grain.

Light Trapping in Silicon Based Tandem Solar Cell: A Brief Review

  • Iftiquar, Sk Md;Park, Hyeongsik;Dao, Vinh Ai;Pham, Duy Phong;Yi, Junsin
    • Current Photovoltaic Research
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    • v.4 no.1
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    • pp.1-7
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    • 2016
  • Among the various types of solar cells, silicon based two terminal tandem solar cell is one of the most popular one. It is designed to split the absorption of incident AM1.5 solar radiation among two of its component cells, thereby widening the wavelength range of external quantum efficiency (EQE) spectra of the device, in comparison to that of a single junction solar cell. In order to improve the EQE spectra further and raise short circuit current density ($J_{sc}$) an optimization of the tradeoff between the top and bottom cell is needed. In an optimized cell structure, the $J_{sc}$ and hence efficiency of the device can further be enhanced with the help of light trapping scheme. This can be achieved by texturing front and back surface as well as a back reflector of the device. In this brief review we highlight the development of light trapping in the silicon based tandem solar cell.

Correlation Between Apoptosis and Intratumoral Microvessel Density in Non-Small Cell Lung Cancer. (비소세포 폐암에서 아포프토시스와 종양내 미세 혈관 밀도의 관계)

  • 장인석;김종우;김진국;한정호
    • Journal of Chest Surgery
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    • v.32 no.2
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    • pp.151-157
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    • 1999
  • Background: Increasing evidences from experimental studies indicate that apoptosis may be inversely related to angiogenesis in tumor progression. Material and Method: To explore how apoptosis correlates with tumor angiogenesis, we measured the apoptotic index(AI) using the terminal deoxynucleotidyl transferase method(Apop Tag In Situ Apoptosis Detection Kit, ONCOR) and the intratumoral microvessel density using the anti-CD31 monoclonal antibody in non-small cell lung cancer. Result: Statistical analysis revealed an inverse correlation between AIs and intratumoral microvessel densities in squamous cell lung carcinoma(Spearman rank correlation coefficient r=- 0.229, p=0.047). Conclusion: The results of this study demonstrated that the amount of apoptosis in squamous cell lung carcinoma may be influenced by the extent of neovascularization. This suggests that tumor angiogenesis may contribute to a reduction of apoptosis in tumor cells.

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Improvement of Power Generation of Microbial Fuel Cells using Maximum Power Point Tracking (MPPT) and Automatic Load Control Algorithm (최대전력점추적방법과 외부저항 제어 알고리즘을 이용한 미생물연료 전지의 전력생산 최대화)

  • Song, Young Eun;Kim, Jung Rae
    • KSBB Journal
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    • v.29 no.4
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    • pp.225-231
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    • 2014
  • A microbial fuel cell (MFC) and bioelectrochemical systems are novel bioprocesses which employ exoelectrogenic biofilm on electrode as a biocatalyst for electricity generation and various useful chemical production. Previous reports show that electrogenic biofilms of MFCs are time varying systems and dynamically interactive with the electrically conductive media (carbon paper as terminal electron acceptor). It has been reported that maximum power point tracking (MPPT) method can automatically control load by algorithm so that increase power generation and columbic efficiency. In this study, we developed logic based control strategy for external load resistance by using $LabVIEW^{TM}$ which increases the power production with using flat-plate MFCs and MPPT circuit board. The flat-plate MFCs inoculated with anaerobic digester sludge were stabilized with fixed external resistance from $1000{\Omega}$ to $100{\Omega}$. Automatic load control with MPPT started load from $52{\Omega}$ during 120 hours of operation. MPPT control strategy increased approximately 2.7 times of power production and power density (1.95 mW and $13.02mW/m^3$) compared to the initial values before application of MPPT (0.72 mW and $4.79mW/m^3$).

Advanced Tellurium-Based Threshold Switching Devices for High-Density Memory Arrays (Tellurium 기반 휘발성 문턱 스위칭 및 고집적 메모리용 선택소자 응용 연구)

  • Seunghwan Kim;Changhwan Kim;Namwook Hur;Joonki Suh
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.36 no.6
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    • pp.547-555
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    • 2023
  • High-density crossbar arrays based on storage class memory (SCM) are ideally suited to handle an exponential increase in data storage and processing as a central hardware unit in the era of AI-based technologies. To achieve this, selector devices are required to be co-integrated with SCM to address the sneak-path current issue that indispensably arises in such crossbar-type architecture. In this perspective, we first summarize the current state of tellurium-based threshold-switching devices and recent advances in the material, processing, and device aspects. We thoroughly review the physicochemical properties of elemental tellurium (Te) and representative binary tellurides, their tailored deposition techniques, and operating mechanisms when implemented in two-terminal threshold switching devices. Lastly, we discuss the promising research direction of Te-based selectors and possible issues that need to be considered in advance.

Unsteady Mass Transfer Around Single Droplet Accompanied by Interfacial Extraction Reaction of Succinic Acid (숙신산 추출반응이 일어나는 단일 액적계에서의 비정상상태 물질 전달)

  • Jeon, Sangjun;Hong, Won Hi
    • Korean Chemical Engineering Research
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    • v.50 no.6
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    • pp.1021-1026
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    • 2012
  • The transient mass transfer in a single droplet system consisting of 1-octanol (continuous phase)/aqueous succinic acid solution (dispersed phase) was investigated in the presence of chemical reaction, which is acid/anion exchange reaction of succinic acid and tri-n-octylamine (TOA). This succinic acid extraction by TOA can be considered to occur at the interface between organic and aqueous phase, that is, heterogeneous reaction system. The basic properties of the system such as viscosity, density, distribution coefficient, terminal velocity of droplet, and diffusion coefficient were measured experimentally or calculated theoretically, and used for theoretical calculation of characteristic parameters of mass transfer later. The effects of succinic acid concentration on the terminal velocity was negligible in the existence of TOA, although the terminal velocity increases with succinic acid concentration in the absence of TOA. On the contrary, the terminal velocity decreases with TOA concentration. While droplets falls through organic phase, the trajectory of droplets is observed to oscillate around its vertical path. A mass trnasfer cell was prepared to monitor the mass transfer behavior in a single droplet and used to measure the mean concentration of succinic acid inside droplet. The results are expressed with dimensionless parameters. Under 50 g/L succinic acid condition, the system with 0.1 mol/kg TOA showed that the molar flux decreases in proportion to the decrease of concentration gradient, while in the case of 0.5 mol/kg TOA Sh increases rapidly with time indicating the molar flux of succinic acid decreases relatively slowly compared to the decrease in concentration gradient.