• Title/Summary/Keyword: technology trends

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The Classification System and Information Service for Establishing a National Collaborative R&D Strategy in Infectious Diseases: Focusing on the Classification Model for Overseas Coronavirus R&D Projects (국가 감염병 공동R&D전략 수립을 위한 분류체계 및 정보서비스에 대한 연구: 해외 코로나바이러스 R&D과제의 분류모델을 중심으로)

  • Lee, Doyeon;Lee, Jae-Seong;Jun, Seung-pyo;Kim, Keun-Hwan
    • Journal of Intelligence and Information Systems
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    • v.26 no.3
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    • pp.127-147
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    • 2020
  • The world is suffering from numerous human and economic losses due to the novel coronavirus infection (COVID-19). The Korean government established a strategy to overcome the national infectious disease crisis through research and development. It is difficult to find distinctive features and changes in a specific R&D field when using the existing technical classification or science and technology standard classification. Recently, a few studies have been conducted to establish a classification system to provide information about the investment research areas of infectious diseases in Korea through a comparative analysis of Korea government-funded research projects. However, these studies did not provide the necessary information for establishing cooperative research strategies among countries in the infectious diseases, which is required as an execution plan to achieve the goals of national health security and fostering new growth industries. Therefore, it is inevitable to study information services based on the classification system and classification model for establishing a national collaborative R&D strategy. Seven classification - Diagnosis_biomarker, Drug_discovery, Epidemiology, Evaluation_validation, Mechanism_signaling pathway, Prediction, and Vaccine_therapeutic antibody - systems were derived through reviewing infectious diseases-related national-funded research projects of South Korea. A classification system model was trained by combining Scopus data with a bidirectional RNN model. The classification performance of the final model secured robustness with an accuracy of over 90%. In order to conduct the empirical study, an infectious disease classification system was applied to the coronavirus-related research and development projects of major countries such as the STAR Metrics (National Institutes of Health) and NSF (National Science Foundation) of the United States(US), the CORDIS (Community Research & Development Information Service)of the European Union(EU), and the KAKEN (Database of Grants-in-Aid for Scientific Research) of Japan. It can be seen that the research and development trends of infectious diseases (coronavirus) in major countries are mostly concentrated in the prediction that deals with predicting success for clinical trials at the new drug development stage or predicting toxicity that causes side effects. The intriguing result is that for all of these nations, the portion of national investment in the vaccine_therapeutic antibody, which is recognized as an area of research and development aimed at the development of vaccines and treatments, was also very small (5.1%). It indirectly explained the reason of the poor development of vaccines and treatments. Based on the result of examining the investment status of coronavirus-related research projects through comparative analysis by country, it was found that the US and Japan are relatively evenly investing in all infectious diseases-related research areas, while Europe has relatively large investments in specific research areas such as diagnosis_biomarker. Moreover, the information on major coronavirus-related research organizations in major countries was provided by the classification system, thereby allowing establishing an international collaborative R&D projects.

A Design Direction for Mobile phones between Comparison of Users from Korea, China and Japan (한중일 사용자 비교분석을 통한 모바일폰 디자인 방향)

  • Eune, Ju-Hyun;Jung, Hee-Yun;Kim, Yun-Jun
    • Archives of design research
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    • v.20 no.3 s.71
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    • pp.29-38
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    • 2007
  • The competition to capture a larger slice of the market in Mobile Communication business is increasing among companies. In order to achieve and maintain a competitive advantage in the Asian market, it is critical to continue to develop new technology. Understanding the underlying distinctive characteristics and needs of each market and the cultural backgrounds that drive those needs is a necessary focus. Companies with marketing strategies based on a correct understanding of market needs will capture dominant positions in the market. The purpose of this study is to identify those differences in user behavior and cultural tendencies among different people in different countries in the mobile telecommunication market. This research is based on an on-line survey in three countries (Korea, China, and Japan). Below are the contents of the survey on the mobile phone based on: 1) User behavior 2) Design preference 3) Purchasing behavior 4) User awareness on manufacturer brand. Through the analysis of this questionnaire it is possible to identify the differences and similarities among countries dearly. 1) Cultural trends and perceptions related to mobile phone usage were largely caused by differences in the state of technology, policies and business strategies of mobile sonics carriers and manufacturers, and national tendencies, of each country. 2) Korean and Japanese users produced similar responses to the questions related to advanced technology, whereas Korean and Chinese users responded similarly to national tendency-related questions. 3) To the questions related to business strategies of mobile service carriers and manufacturers, users in all three countries displayed markedly different responses. Once again, accurate analysis of the differences and similarities related to mobile phone usage in each country will help the companies in this industry to gain a competitive edge in the market. This study should not stop at simple comparison but be a framework for giving companies a dear future direction for technological development.

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Variability of Satellite-derived Chlorophyll-a Concentration in Relation to Indian Ocean Dipole (IOD) Variation (인도양 쌍극진동 변동에 따른 위성에서 추정된 표층 클로로필-a 농도 변화 연구)

  • Son, Young Baek;Kim, Suk Hyun;Kim, Sang-Hyun;Rho, TaeKeun
    • Korean Journal of Remote Sensing
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    • v.33 no.6_1
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    • pp.917-930
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    • 2017
  • To understand the temporal and spatial variations of surface chlorophyll-a concentration (Chl-a) distribution in the Indian Ocean ($30^{\circ}E{\sim}120^{\circ}E$, $30^{\circ}S{\sim}30^{\circ}N$) by the Indian Ocean Dipole (IOD), we conducted EOF and K means analyses of monthly satellite-derived Chl-a data in the region during 1998~2016 periods. Chl-a showed low values in the central region of the Indian Ocean and relatively high values in the upwelling region and around the marginal regions of the Indian Ocean. It also had a strong seasonal variation of Chl-a, showing the lowest value in the spring and the highest value in summer due to the change of the monsoon and current system. The EOF analysis showed that Chl-a variation in EOF mode 1 is related to ENSO (El $Ni{\tilde{n}}o$/Southern Oscillation) and that of mode 2 is linked to IOD. Both modes explained spatially opposite trends of Chl-a in the east and west Indian Ocean. From K means analysis, the Chl-a variation in the east and west Indian Ocean, and around India have relatively good relationship with IOD while that in the tropical and middle Indian Ocean closely associated with ENSO. The spatial and temporal distribution of Chl-a also showed distinct spatial and temporal variations depend on the different types of IOD events. IOD classifies two patterns, which occurred during the developing ENSO (First Type IOD) and the year following ENSO event (Second Type IOD). Chl-a variation in the First Type IOD started in summer and peaked in fall around the east and west Indian Ocean. Chl-a variation in the Second Type IOD occurred started in spring, peaked in summer and fall, and disappeared in winter. In the Chl-a variation related to IOD, developing process appearing in the Chl-a difference between the east and west Indian ocean was similar. Chl-a variation in the northern Indian Ocean were opposite trend with changing developing phase of IOD.

Analysis of Stress Response of Domestic Chicken Breeds for the Development of a New Synthetic Parent Stock (국산 종계 개발을 위한 토종 계통들의 스트레스 반응 정도 분석)

  • Sohn, Sea Hwan;Cho, Eun Jung;Park, Ji Ae;Hong, Young Ho;Kim, Chong Dae
    • Korean Journal of Poultry Science
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    • v.42 no.2
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    • pp.157-167
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    • 2015
  • We compared the degrees of stress response of 12 domestic purebred chicken strains that have been bred at National Institute of Animal Science, RDA, Korea since 1980. As a physiological marker of stress response, the expression levels of heat shock protein (HSP)-70, HSP-$90{\alpha}$, HSP-$90{\beta}$, hydroxyl-3-methyl-glutaryl coenzyme A reductase (HMGCR) genes and telomere length were measured by quantitative real-time polymerase chain reaction using the lymphocytes of 1,101 chickens. There was significant difference in HSP-70, HSP-$90{\alpha}$, HMGCR expression and telomere length among the strains. There was also significant difference in HSP-$90{\alpha}$, HSP-$90{\beta}$, and HMGCR expression between male and female chickens. Different age groups of chicken exhibited different expression levels of HSP-70, HSP-$90{\alpha}$ and telomere length. The results of the HSPs expression level suggested that, the strains of R, L and Y were highly resistant to stress, whereas the strains of S, O and W were susceptible to stress. Although the statistical differences in some of HSPs gene expression existed between genders, the HSP expression results varied in different strains that some opposed to the others, and there might be interaction between strains and genders, which conclude that there was no difference in stress response between male and female chickens. Moreover, despite of significant difference in some of HSPs expression level, it was considered that there was no difference in stress response between ages due to the inconsistent trends among HSP markers.

Stress Patterns in the Reconstructed Double Bundles of the Anterior Cruciate Ligament in Response to an Anterior Tibial Load and Rotatory Load: an Analysis using a 3-Dimensional Finite Element Model (삼차원 유한 요소 모델을 이용한 전방십자인대 이중다발 재건술 후 전방 전위 및 회전 부하에 따른 이식건 응력 양상 분석)

  • Seo, Young-Jin;Song, Si Young;Ahn, Jung Tae;Kim, Yoon-Sang;Ko, Jun Ho;Jang, Seong-Wook;Yoo, Yon-Sik
    • Journal of the Korean Arthroscopy Society
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    • v.16 no.2
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    • pp.160-166
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    • 2012
  • Purpose: The aim of this study was to determine the patterns of the stress distribution within the reconstructed anterior cruciate ligament (ACL) double bundles in response to an anterior tibial load and rotatory load at $45^{\circ}$ flexed knee model by use of a 3-dimensional finite element analysis (FEM). Materials and Methods: The $0^{\circ}$ and $45^{\circ}$ flexed 3-D knee model were reconstructed based on the high resolution computed tomography (CT) images from the right knee of a healthy male subject. To simulate double bundle ACL reconstruction, in $0^{\circ}$ analytic model, four 7 mm diameter tunnels were created at the center of each anteromedial (AM) and posterolateral (PL) footprints on the femur and tibia. The grafts were inserted into the corresponding bone tunnels and then reconstructed knee model was flexed to $45^{\circ}$. As a next step, the 5 mm anterior tibial load and internal rotational load of $10^{\circ}$ were applied on the final Computer aided design (CAD) model. And then stress patterns of each bundle were assessed using a finite element analysis. Results: In response to the 5 mm of anterior tibial load, the AM bundle showed increased stresses around the tibial and femoral attachment sites; especially in the anterior aspect of the bundle. In the PL bundle, the highest stress concentration was also noticed on the anterior aspect of the bundle. Under $10^{\circ}$ internal rotational load, the stress concentration was predominant around the anterior aspect of the tibial attachment site within the AM bundle. The PL bundle also showed highest stress concentration on the anterior aspect of the bundle. Conclusion: Although the stress patterns were not identical among the AM and PL bundle, there were common trends in the stress distribution. The stress concentration was predominant on the anterior aspect of both bundles in response to the anterior tibial load and rotatory load.

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Pollutants Behavior in Oxy-CFBC by Application of In-Furnace deSOx/deNOx Method (순산소 순환유동층에서 로내 탈황 및 탈질법 적용에 따른 오염물질 거동특성)

  • Choi, Gyung-Goo;Na, Geon-Soo;Shin, Ji-Hoon;Keel, Sang-In;Lee, Jung-Kyu;Heo, Pil-Woo;Yun, Jin-Han
    • Clean Technology
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    • v.24 no.3
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    • pp.212-220
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    • 2018
  • Oxy-fuel combustion is considered as a promising greenhouse gas reduction technology in power plant. In this study, the behaviors of NO and $SO_2$ were investigated under the condition that in-furnace $deNO_x$ and $deSO_x$ methods are applied in oxy-fuel circulating fluidized bed combustion condition. In addition, the generation trends of $SO_3$, $NH_3$ and $N_2O$ were observed. For the purpose, limestone and urea solution were directly injected into the circulating fluidized bed combustor. The in-furnace $deSO_x$ method using limestone could reduce the $SO_2$ concentration in exhaust gas from ~403 to ~41 ppm. At the same experimental condition, the $SO_3$ concentration in exhaust gas was also reduced from ~3.9 to ~1.4 ppm. This trend is mainly due to the reduction of $SO_2$. The $SO_2$ is the main source of the formation of $SO_3$. The negative effect of $CaCO_3$ in limestone, however, was also appeared that it promotes the NO generation. The NO concentration in exhaust gas reduced to ~26 - 34 ppm by appling selective non-catalytic reduction method using urea solution. The $NH_3$ concentration in exhaust gas was appeared up to ~1.8 ppm during injection of urea solution. At the same time, the $N_2O$ generation also increased with increase of urea solution injection. It seems that the HNCO generated from pyrolysis of urea converted into $N_2O$ in combustion atmosphere. From the results in this study, the generation of other pollutants should be checked as the in-furnace $deNO_x$ and $deSO_x$ methods are applied.

Synthetic Application of Seismic Piezo-cone Penetration Test for Evaluating Shear Wave Velocity in Korean Soil Deposits (국내 퇴적 지반의 전단파 속도 평가를 위한 탄성파 피에조콘 관입 시험의 종합적 활용)

  • Sun, Chang-Guk;Kim, Hong-Jong;Jung, Jong-Hong;Jung, Gyung-Ja
    • Geophysics and Geophysical Exploration
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    • v.9 no.3
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    • pp.207-224
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    • 2006
  • It has been widely known that the seismic piezo-cone penetration test (SCPTu) is one of the most useful techniques for investigating the geotechnical characteristics such as static and dynamic soil properties. As practical applications in Korea, SCPTu was carried out at two sites in Busan and four sites in Incheon, which are mainly composed of alluvial or marine soil deposits. From the SCPTu waveform data obtained from the testing sites, the first arrival times of shear waves and the corresponding time differences with depth were determined using the cross-over method, and the shear wave velocity $(V_S)$ profiles with depth were derived based on the refracted ray path method based on Snell's law. Comparing the determined $V_S$ profile with the cone tip resistance $(q_t)$ profile, both trends of profiles with depth were similar. For the application of the conventional CPTu to earthquake engineering practices, the correlations between $V_S$ and CPTu data were deduced based on the SCPTu results. For the empirical evaluation of $V_S$ for all soils together with clays and sands which are classified unambiguously in this study by the soil behavior type classification index $(I_C)$, the authors suggested the $V_S-CPTu$ data correlations expressed as a function of four parameters, $q_t,\;f_s,\;\sigma'_{v0}$ and $B_q$, determined by multiple statistical regression modeling. Despite the incompatible strain levels of the downhole seismic test during SCPTu and the conventional CPTu, it is shown that the $V_S-CPTu$ data correlations for all soils, clays and sands suggested in this study is applicable to the preliminary estimation of $V_S$ for the soil deposits at a part in Korea and is more reliable than the previous correlations proposed by other researchers.

The Influences of Additional Nutrients on Phytoplankton Growth and Horizontal Phytoplankton Community Distribution during the Autumn Season in Gwangyang Bay, Korea (가을철 광양만 식물플랑크톤의 수평 분포와 추가 영양염 공급이 식물플랑크톤 성장에 미치는 영향)

  • Bae, Si Woo;Kim, Dongseon;Kim, Young Ok;Moon, Chang Ho;Baek, Seung Ho
    • Korean Journal of Environmental Biology
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    • v.32 no.1
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    • pp.35-48
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    • 2014
  • In order to estimate the effect of additional nutrients on phytoplankton growth and horizontal phytoplankton community distribution during the autumn season in 2010 and 2011, we investigated the abiotic and biotic factors of surface and bottom waters at 20 stations of inner and offshore areas in Gwangyang Bay, Korea. Also, nutrient additional experiments were conducted to assess additional nutrient effects on phytoplankton assemblage using the surface water. In both years, the total nutrients were high at the enclosed inner bay and the mouth of Seomjin River, whereas it was low at the St.15~20 where in influenced by the surface warm water current from offshore of the bay. On the other hand, nano- and pico-sized Chl. a were gradually increased towards the outer bay and their trends were significant in 2011 than in 2010. The cryptophyta species occupied more than 85% of total phytoplankton assembleges in 2010, whereas their abundance in 2011 remainds to be 1/10 levels of 2010. Following the cryptophata species, the diatom Chaetoceros spp. and Skeletonema-like spp. were found to be dominant species. Further the biosaasy experimental results shows that the phytoplankton biomass in the +N and +NP treatments was higher compared to control and +P treatments and its trend was significant at St.8 and St.20 where nutrient concentration were low. Based on the bioassay and field survey, providing the high nutrients may have stimulated to phytoplankton growth such as S. costatum-like spp.. In particular, opportunistic micro-algae such as Cryptomonas spp. were able to achieve the high biomass under the relatively mid nutrient condition from bottom after break down of seasonal stratification in the Gwangyang Bay.

Variation in Muscle Lipids and Fatty Acid Composition of Neutral and Phospholipids of Mudskipper (Boleophthalmus pectinirostris) during Hibernation (동면중 짱뚱어 근육유(筋肉油)의 지방질과 중성 및 인지질 조성의 변화)

  • Kim, Myung-Kon;Baek, Seung-Hwa;Choe, Sun-Nam;Kim, Jong-Bae;Park, Il-Woong
    • Applied Biological Chemistry
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    • v.41 no.7
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    • pp.533-538
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    • 1998
  • In order to gain fundamental information on the utilization of lipids as energy source in mud-skipper, muscle lipids and their fatty acid composition were investigated with respect to life cycle-maturation (Aug), before-hibernation (Nov), and after-hibernation (Apr). Crude and neutral lipid were found to decrease from 1.2, 68.3% (Aug) via 0.7, 53.8% (Nov) to 0.4, 42.6% (Apr), respectively, whilst phospholipids and glycolipids increased from 29.5 and 2.2% (Aug) to 52.1 and 5.3% (Apr), respectively. In neutral lipids, TG contents gradually decreased from 53.8% (Aug) via 33.6% (Nov) to 23.1% (Apr), while FFA and sterol contents increased from 13.5 and 14.2% (Aug) to 22.3 and 24.5% (Apr), respectively. In phospholipids, PC content decreased from 61.2% (Aug) to 50.6% (Apr), while changes in PS and PE contents, as a whole, showed the opposite trends. In neutral lipids, the levels of some fatty acids such as 16:0, 16:1, 18:0, 18:1 and 20:5 $({\omega}3)$ were analyzed to be high, with the 20 : 5 being predominant, and the levels of saturated and monoene-acids gradually decreased, while polyene-acids increased in before and after hibernation. In before hibernation, 16:0, 16:1, 18:1 mainly decreased but 18:2, 18:3 $({\omega}3)$ and most of saturated and monoene acids such as 14:0, 14:1, 16:1, 18:0, 18:1 slightly decreased in after hibernation. From these findings, it was suggested that those fatty acids decreased during hibernation were used as a energy source, particularly 16:1 and 18:1 being most preferentially used. In phospholipids, the levels of 16:0, 18:0, 20:5 $({\omega}3)$, 22:5 $({\omega}3)$ and 22:6 $({\omega}3)$ were found to be high. Throughout the life cycle, the levels of monoene-acids in phospholipids stayed constant, whilst those of 18:2, 18:3 $({\omega}3)$ and saturated acids such as 16:0, 18:0 were found to be decreased gradually in before and after hibernation, whereas those for the high degree of polyene-acids such as 20:4 $({\omega}6)$, 20:5 $({\omega}3)$, 22:5 $({\omega}3)$, 22:6 $({\omega}3)$ increased, particularly 20:4 $({\omega}6)$, 20:5 $({\omega}3)$ being most increased.

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Simulation and Post-representation: a study of Algorithmic Art (시뮬라시옹과 포스트-재현 - 알고리즘 아트를 중심으로)

  • Lee, Soojin
    • 기호학연구
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    • no.56
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    • pp.45-70
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    • 2018
  • Criticism of the postmodern philosophy of the system of representation, which has continued since the Renaissance, is based on a critique of the dichotomy that separates the subjects and objects and the environment from the human being. Interactivity, highlighted in a series of works emerging as postmodern trends in the 1960s, was transmitted to an interactive aspect of digital art in the late 1990s. The key feature of digital art is the possibility of infinite variations reflecting unpredictable changes based on public participation on the spot. In this process, the importance of computer programs is highlighted. Instead of using the existing program as it is, more and more artists are creating and programming their own algorithms or creating unique algorithms through collaborations with programmers. We live in an era of paradigm shift in which programming itself must be considered as a creative act. Simulation technology and VR technology draw attention as a technique to represent the meaning of reality. Simulation technology helps artists create experimental works. In fact, Baudrillard's concept of Simulation defines the other reality that has nothing to do with our reality, rather than a reality that is extremely representative of our reality. His book Simulacra and Simulation refers to the existence of a reality entirely different from the traditional concept of reality. His argument does not concern the problems of right and wrong. There is no metaphysical meaning. Applying the concept of simulation to algorithmic art, the artist models the complex attributes of reality in the digital system. And it aims to build and integrate internal laws that structure and activate the world (specific or individual), that is to say, simulate the world. If the images of the traditional order correspond to the reproduction of the real world, the synthesized images of algorithmic art and simulated space-time are the forms of art that facilitate the experience. The moment of seeing and listening to the work of Ian Cheng presented in this article is a moment of personal experience and the perception is made at that time. It is not a complete and closed process, but a continuous and changing process. It is this active and situational awareness that is required to the audience for the comprehension of post-representation's forms.