• Journal of Life Science
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• v.33 no.2
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• pp.216-226
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• 2023

Since nylon 66, a polyamide resin, has been developed and applied to toothbrush bristles, plastic consumption has increased rapidly every year, along with the increase in the amount of plastic discarded. Among the various forms of plastic debris produced by the decomposition of plastics, microplastics with a size of less than 5 mm are widely distributed in the environment, which poses a threat not only to the environment but also to animals and humans. The pathway through which microplastics enter the human body is known as ingestion by water and food, inhalation from air, and skin contact. Microplastics introduced into the human body affect human health. Recently, food-related studies have begun to be reported among microplastics-related studies, and analyses of the presence of microplastics in processed foods, such as canned foods, dried seaweed, beverages, beer, milk, sugar, and honey, are underway. Here, we present trends in the production and consumption of plastics, the generation of microplastics, the route of human inflow and human risk, and the microplastics present in processed foods, which are limited but have recently been reported. Thus far, studies on microplastics and risk assessment in processed foods have been insufficient, but microplastics are gradually being recognized as a factor that affects the environment and food. Future studies are expected to have implications for regulations regarding microplastics present in processed foods.

• Journal of Life Science
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• v.33 no.9
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• pp.754-765
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• 2023

Exosomes are a type of extracellular vesicle containing proteins and messenger and microRNAs; they are secreted by all cell types. Once released, exosomes are selectively taken up by other cells adjacent or at a distance, releasing their contents and reprogramming the target cells. Since exosomes are natural vesicles produced by cells as small sizes, it is generally accepted that exosomes have a non-toxic nature and non-immunogenic behaviors. Recently, exosomes have elicited scientific attention as drug delivery vehicles to the central nervous system. The central nervous system has a blood-brain barrier that makes it difficult for drugs to penetrate. Thus, the blood-brain barrier has been a major obstacle to the development of drugs for treating neurodegenerative diseases. However, accumulating evidence suggests that exosomes can cross the blood-brain barrier primarily through transcytosis. Consequently, exosomes are expected to become a new delivery vehicle that can cross the blood-brain barrier and deliver drugs into the brain parenchyma. In addition, since different types of exosomes are secreted depending on the cell type and disease state, exosomes can also be utilized as biomarkers for the diagnosis of diseases in the central nervous system. In this review, we summarized recent research trends on exosomes, including clinical trials as biomarkers and treatment options for diseases in the central nervous system.

• Journal of Intelligence and Information Systems
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• v.28 no.1
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• pp.29-43
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• 2022

With the advent of the Internet and the development of mobile digital devices such as smartphones and tablet PCs, the communication service paradigm began to shift from existing voice services to data services. Recently, as social network services (SNS) are activated and 4th industrial revolution technologies centered on ICT (Information and Communication Technologies) such as Big Data, Blockchain, Cloud, and 5G/6G are rapidly developed, the amount of shared data type and the amount of data are increasing rapidly. As the transition to a digital society begins actively, the importance of using data information, as well as the economic and social values of personal information are becoming increasingly important. As a result, they are actively discussing policies to revitalize the data information industry around the world and ways to efficiently obtain, analyze, and utilize increasingly diverse and vast data, as well as to protect/guarantee the rights of information subjects (providers) in various fields such as society, culture, economy, and politics.. In this paper, in order to improve the self-determination right of personal information on data produced by information subjects, and further expand the use of safe data and the data economy, a differentiated data trusts system was considered and suggested. In addition, the components and data trusts procedures necessary to efficiently operate the data trusts system in Korea were considered, and the non-profit data trusts system and the for-profit data trusts system were considered as a way to flexibly operate the data trusts system. Furthermore, the legal items necessary for the implementation of the data trusts system were investigated and considered. In this paper, in order to propose a domestic data trusts system, cases related to existing data trusts systems such as the United States, Japan, and Korea were reviewed and analyzed. In addition, in order to prepare legislation necessary for the data trusts system, data-related laws in major countries and domestic legal and policy trends were reviewed to study the rights that conflict or overlap with existing laws, and differences were investigated and considered. The Data trusts system proposed in this paper is a reasonable system that is expected to recognize the asset value of data in the capitalist market economy system, to provide legitimate compensation for data produced by data subjects, and further to contribute greatly to the use of safe data and creation of a new service market.

• Communications of Mathematical Education
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• v.36 no.1
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• pp.1-21
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• 2022

The purpose of this study is to analyze the current situation of EduTech, which is proposed as a way to build a flexible learning environment regardless of time and place according to the use of digital technology in mathematics subjects. The process of designing classes to use the EduTech platform, which is still in the development introduction stage, in public education is still difficult, and research to observe its effects and characteristics is also in its early stages. However, in the stage of preparing for future education, it is a meaningful process to grasp the current situation and point out the direction in preparation for the future in which EduTech will be actively applied to education. Accordingly, the current situation and utilization trends of EduTech at home and abroad were confirmed, and the functions and roles of EduTech platforms used in mathematics were analyzed. As a result of the analysis, the EduTech platform was pursuing learners' self-directed learning by constructing its functions so that they could be useful for individual learning of learners in hierarchical mathematics education. In addition, we have confirmed that the platform is evolving to be useful for teachers' work reduction, suitable activities, and evaluations learning management. Therefore, it is necessary to implement instructional design and individual customized learning support measures for students that can efficiently utilize these platforms in the future.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.85-107
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• 2022

This study is to analyze the induced effect, network connectivity, and network visualization of the water transportation industry on the overall economy in relation to all industries. For this, various inducement coefficients of the water transportation industry are analyzed using industry linkage analysis and unit structure matrix, and network visualization analysis is performed using network connectivity and NetDraw using Ucinet 6 that utilizes unit structure matrix and inverse matrix function. As a result of the study, analysis results of input coefficient, production inducement coefficient, value-added inducement coefficient, and inter-industry chain effect were presented as various inducement coefficients in the water transportation industry. content was presented. Through this study, the current position and status of the water transportation industry and its relationship with all industries were confirmed, and the strategic relationship with which industries it should be presented was presented. In the future, it is necessary to further analyze the current status and trends of various induced effects, connectivity (centrality), and network visualization analysis using industry-related analysis published since the 2000s.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.8 no.11
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• pp.11-20
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• 2018

The Korean Statistical Information Service (KOSIS), classifies and summarizes 1,062 cases that were found when searching [An Investigation on Multicultural Families in Korea] on the website. These years are 2009, 2012, and 2015. The suggestion of this study is as follows. First, it is a comparison between the migrant group and the permanent resident group of 'children' in the research data. Identifying the relative position of a married migrant family to a permanent resident can provide a very important clue. Also, for other date, comparison of the settled and migrant groups is as important as the 'children'. Second, in the 'medical care' category, we need to add more depth than the surface content. For example, the inclusion of details about cancer diagnosis will determine the incidence of marriage migrants. Such efforts can provide more practical assistance to married migrant families. KOSIS is a very useful site that provides useful site that provides us with a lot of information. In the future, they should be able to use migrant group information more efficiently and be more helpful to them. This is the beginning of a sustainable society.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.313-353
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• 2023

Objectives: Heart failure is a chronic disease with increasing prevalence rates despite advancements in medical technology. Korean medicine utilizes herbal prescriptions to treat heart failure, but little is known about the specific herbal medicines comprising the network of herbal prescriptions for heart failure. This study proposes a novel methodology that can efficiently develop prescriptions and facilitate experimental research on heart failure by utilizing existing databases. Methods: Herbal medicine prescriptions for heart failure were identified through a PubMed search and compiled into a Google Sheet database. NetMiner 4 was used for network analysis, and the individual networks were classified according to the herbal medicine classification system to identify trends. K-HERB NETWORK was utilized to derive related prescriptions. Results: Network analysis of heart failure prescriptions and herbal medicines using NetMiner 4 produced 16 individual networks. Uhwangcheongsim-won (牛黃淸心元), Gamiondam-tang (加味溫膽湯), Bangpungtongseong-san (防風通聖散), and Bunsimgi-eum (分心氣飮) were identified as prescriptions with high similarity in the entire network. A total of 16 individual networks utilized K-HERB NETWORK to present prescriptions that were most similar to existing prescriptions. The results provide 1) an indication of existing prescriptions with potential for use to treat heart failure and 2) a basis for developing new prescriptions for heart failure treatment. Conclusion: The proposed methodology presents an efficient approach to developing new heart failure prescriptions and facilitating experimental research. This study highlights the potential of network pharmacology methodology and its possible applications in other diseases. Further studies on network pharmacology methodology are recommended.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.5D
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• pp.443-451
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• 2010

This paper proposes the methodology about advisory safety speed based on real-time vehicular data collected from highway. The proposed model is useful information to drivers by appling seamless wireless communication and being collected from ECU(Engine Control Unit) equipment in every vehicle. Furthermore, this model also permits the use of realtime sensing data like as adverse weather and road-surface data. Here, the advisory safety speed is defined "the safety speed for drivers considering the time-dependent traffic condition and road-surface state parameter at uniform section", and the advisory safety speed model is developed by considering the parameters: inter-vehicles safe stopping distance, statistical vehicle speed, and real-time road-surface data. This model is evaluated by using the simulation technique for exploring the relationships between advisory safety speed and the dependent parameters like as traffic parameters(smooth condition and traffic jam), incident parameters(no-accident and accident) and road-surface parameters(dry, wet, snow). A simulation's results based on 12 scenarios show significant relationships and trends between 3 parameters and advisory safety speed. This model suggests that the advisory safety speed has more higher than average travel speed and is changeable by changing real-time incident states and road-surface states. The purpose of the research is to prove the new safety related services which are applicable in SMART Highway as traffic and IT convergence technology.

• Journal of Navigation and Port Research
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• v.47 no.3
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• pp.120-127
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• 2023

Maritime pilots are always exposed to unpredictable risks present in the marine environment because they are boarding ships through pilot ladders or accommodation ladders at sea. Since the pilot plays an important role in securing the safety of a ship entering or departing from a port, an injury to the pilot substantially affects the overall safety of the ship. The purpose of this study is to analyze pilot injuries and predict accidents. For this purpose, pilot injury cases are analyzed and potential situations are identified through a survey. Pilot injuries are also predicted. The survey was analyzed using the IPA (Importance-Performance Analysis) methodology, and the binomial distribution and Poisson distribution were used to predict injury trends. As a result of the study, 316.8 nearmiss occurred per pilot injury, and if the current accident management system is maintained, the probability of pilot injury occurring within 3 months is 64.4%. Based on the research results, the need for a management system to prevent pilot injuries and reinforcement of maintenance and installation for pilot ladders was suggested.

• Informatization Policy
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• v.30 no.4
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• pp.40-61
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• 2023

The adoption of smart factories and smart manufacturing as strategies to enhance competitiveness and stimulate growth in the manufacturing sector is vital for a country's future competitiveness and industrial transformation. The government has consistently pursued smart manufacturing innovation policies starting with the Manufacturing Innovation 3.0 strategy in the Ministry of Industry. This study aims to identify policy areas for smart factories and smart manufacturing based on technical standards. Analyzing policy areas at the current stage where the establishment and support of domestic standards aligning with international technical standards are required is crucial. By prioritizing smart manufacturing process areas within the industry, policymakers can make well-informed decisions to advance smart manufacturing without blindly following international standardization in already well-established areas. To achieve this, the study utilizes a hierarchical analysis method including expert interviews and importance-performance analysis for the five major process areas. The findings underscore the importance of proactive participation in standardization for emerging technologies, such as data and security, instead of solely focusing on areas with extensive international standardization. Additionally, policymakers need to consider carbon emissions, energy costs, and global environmental challenges to address international trends in export and digital trade effectively.