Lee, Hyo Jeong;Kang, Young Won;Lee, Soo Min;An, Kyung A;Lee, Ryun Kyung;Seo, Sang Cheol;Lee, Ju Hee;Im, Moo Hyeog;Lee, Jeong Rim;Hong, Choong Man;Chang, Moon Ik;Cho, Yoon Jae
Korean Journal of Food Science and Technology
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v.46
no.3
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pp.288-294
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2014
Penicillin and its salts, including the benzatine, procaine, and sodium salts, have been widely used in human and veterinary medicine. Owing to their low toxicity, they currently form the most important group of antibiotics. However, overdose and abuse of these antibiotics may lead to potential risk in human health. Therefore, this study was conducted to validate the analysis method established by the Korea Food Code in 2012 and to monitor the levels of benzylpenicillin residues in products with reference to the maximum residue level (MRL). Of the 232 product samples tested, benzylpenicillin was detected in 11 livestock products and 2 marine products. Benzylpenicillin concentrations were found to be lower than the MRL in 12 products; however, the concentration of benzylpenicillin was found to be greater than the MRL in 1 pork product. The limit of quantification (LOQ) for benzylpenicillin was found to be 0.001-0.002 mg/kg, with an average recovery of 90.4-115.3%. Calibrations showed good linearity of 0.995 over a range of 0.002-0.05 mg/kg.
The evaluation of the degree of compaction of the embankment area, which accounts for most of highway earthworks, is generally performed by a flat plate loading test. The plate loading test is a traditional test method and has high reliability in the field. However, as reaction force equipment must be carried out and it takes about 40 minutes per site during the test, there may be limitations in managing the entire expanse of earthworks. Meanwhile, in order to overcome this, the Ministry of Land, Infrastructure and Transport proposed a simple method of evaluating the level of compactness in the provisional guidelines for compaction management of the packaging infrastructure in 2010. However, it has not been utilized at the highway construction site until now, 10 years later. Therefore, this study attempted to verify the utility of the compaction evaluation method using LFWD (Light Falling Weight Deflectometer) of the impact loading method among the test methods suggested in the provisional guideline. To this end, the correlation was derived by conducting a plate loading test and an LFWD test for each site property and compaction degree. As a result of the test, there was no consistency of test data in the ground with a relative compaction of 80% or less. However, it was confirmed that the correlation has a tendency to increase beyond that. If the test method or test equipment is improved to ensure the consistency of the test values of the impact loading method in the future, it will play a big role in solving the blind spot for compaction management in the earthworks.
Journal of the Korea Institute of Building Construction
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v.22
no.3
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pp.305-316
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2022
Domestic construction companies have difficulty in establishing strategies when entering overseas markets because they do not have an overseas construction economic sentiment index to refer to for data on overseas construction prospects. Considering that the fluctuation of overseas construction orders over the past decade has been substantial and large companies and SMEs are actively advancing overseas, this study developed an evaluation model for an overseas construction business sentiment index to grasp the economic experience of overseas construction companies. In 2021 Korean companies earned 30.6 billion in overseas construction contracts, 87% the level of the previous year, despite difficulties such as COVID-19 and low oil prices, thanks to efforts by construction companies to strengthen their strategies for entry, such as regional diversification, and government support for winning orders. Since the overseas construction industry fluctuates greatly due to changes in the international environment, it is necessary to investigate and analyze the economic sentiment index of overseas construction companies. In particular, despite the increase in overseas expansion of small and medium-sized construction companies and engineering companies, the provision of information on the overseas construction market sentiment index is insufficient, limiting the establishment of strategies for overseas construction expansion. Therefore, this study intends to develop an overseas construction market sentiment index model that can understand the economic sentiment of overseas construction companies, provide a forecast for overseas construction, and use it to establish overseas construction strategies and policies.
Background: The polycystic ovary syndrome (PCOS), characterized by hyperandrogenism and chronic anovulation, is a common endocrine disorder in women. PCOS, which is associated with polycystic ovaries, hirsutism, obesity and insulin resistance, is a leading cause of female infertility. In this condition there is an imbalance in female sex hormones. All the sequelae symptoms of PCOS gradually lead to cancer in the course of time. It is heterogeneous disorder of unknown etiology so it is essential to find the exact cause. Materials and Methods: In this study both invasive and non-invasive techniques were employed to establish the etiology. Diagnosis was based on Rotterdam criteria (hyperandrogenism, ovulatory dysfunction, PCOM) and multiparameters using buccal samples and dermatoglypic analysis and cytogenetic study for 10 cases and four age and sex matched controls. Results: In clinical analysis we have observed the mean value of total testosterone level was 23.6nmol/L, total hirsutism score was from 12-24, facial acne was found in in 70% patients with 7-12 subcapsular follicular cysts, each measuring 2-8 mm in diameter. In dermatoglypic analysis we observed increases in mean value ($45.9^{\circ}$) of ATD angle when compared with control group and also found increased frequency (38%) of Ulnar loops on both fingers (UU), (18%) whorls on the right finger and Ulnar loop on left finger (WU) and (16%) arches on right and left fingers (AA) were observed in PCOS patients when compared with control subjects. Features which could be applied as markers for PCOS patients are the presence of Ulnar loops in middle and little fingers of right and left hand. The buccal micronucleus cytome assay in exfoliated buccal cells, we found decrease in frequency of micronuclei and significant increases in frequency of karyolysed nuclei in polycystic ovarian syndrome patients. Chromosome aberration analysis revealed a significant increase in frequency of chromosome aberrations (CAs) in PCOS patients when compared with controls. Conclusions: From this present work it can be concluded that non-invasive technique like dermatoglypics analysis and buccal micronucleus cytome assays with exfoliated buccal cell can also be effective biomarkers for PCOS, along with increased CAs in lymphocytes as a sign of genetic instability. There is a hypothesis that micronuclei and chromosomal aberrations could have a predictive value for cancer. From this present work it can be concluded to some extent that non-invasive technique like dermatoglypics and buccal cell analysis can also be effective for diagnosis.
The purpose of this study was to investigate the process and meaning of the expansion of the technology education curriculum of general high school. For the study, research problems were set up according to the procedure of case study method, and cases suitable for research were identified and data were collected through interviews with the teachers of the schools. The examples used in the study were two high schools in Gyeonggi - do, and the collected data were visualized in concept form through semantic analysis process. The results of the two schools are summarized as follows. First, the revision of unit school curriculum has been started through crisis and challenge awareness. Second, it is necessary to use the free lecture system suggested in the 2015 revised curriculum. Third, students should change their perceptions of students and curriculum by enhancing class through various skills and education activities suitable for high school level. Fourth, we must continuously strive to develop professionalism as a technology teacher. It is difficult to expand the curriculum of the school because there is only one technology teacher in the general high school. However, through the cases of this study, it is expected that the importance of the technology subject and the change of awareness will be realized as various education activities for the career choice in the high school credit system. do.
Due to the recent development of system semiconductors, technical innovation for the electric devices of the automobile industry is rapidly progressing. In particular, the electric device of automobiles is accelerating technology development competition among automobile parts makers, and the development cycle is also changing rapidly. Due to these changes, the importance of strategic planning for R&D is further strengthened. Due to the paradigm shift in the automobile industry, the Product-Technical Roadmap (P/TRM), one of the R&D strategies, analyzes technology forecasting, technology level evaluation, and technology acquisition method (Make/Collaborate/Buy) at the planning stage. The product-technical roadmap is a tool that identifies customer needs of products and technologies, selects technologies and sets development directions. However, most companies are developing the product-technical roadmap through a qualitative method that mainly relies on the technical papers, patent analysis, and expert Delphi method. In this study, empirical research was conducted through simulations that can supplement and strengthen the product-technical roadmap centered on the automobile industry by fusing Gartner's hype cycle, cumulative moving average-based data preprocessing, and deep learning (LSTM) time series analysis techniques. The empirical study presented in this paper can be used not only in the automobile industry but also in other manufacturing fields in general. In addition, from the corporate point of view, it is considered that it will become a foundation for moving forward as a leading company by providing products to the market in a timely manner through a more accurate product-technical roadmap, breaking away from the roadmap preparation method that has relied on qualitative methods.
Startups play an important role in economic growth and job creation in niche markets, thus governments regularly expand their research and development(R&D) budgets accordingly. As stratups are more dependent on governments to compensate for insufficient resources and capabilities than large and medium-sized companies, trust in government policies will be important. In this study, we analyzed the impact of startups' trust in government R&D policies on innovation performance. There were three major results. The first result is that government R&D investments in startups increase innovation performance in the manufacturing and high-technology industries but did not affect other industries. The second result is that trust in government R&D policies increased innovation in high-and medium-high technology and manufacturing industries. The third result is that trust in government R&D policies affects innovation before, during, and after evaluation of support process. We analyzed the importance of trust to the effectiveness of government R&D support to determine how to effectively provide it. The results show that governments need to differentiate the types of R&D support they provide according to the target firm's technology level and whether they are a manufacturing company and that appropriate R&D support mechanism should be developed for low-technology and non-manufacturing companies. Finally, governments should allocate resources and make fair and transparent decisions to help companies grow, not to better supervise them.
Hoon Moon;Namkon Lee;Jung-Jun Park;Gum-Sung Ryu;Gi-Joon Park;Indong Jang
Journal of the Korean Recycled Construction Resources Institute
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v.11
no.4
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pp.373-380
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2023
This study investigated the carbonation of concrete brick cured in a CO2 environment for the utilization of CO2 captured in power plants. Concrete brick specimens were produced with electric arc furnace reducing slag (ERS) and electric arc furnace oxidizing slag (EOS), and cured for 3 days in a CO2 chamber with a concentration of 20 % or in a constant temperature and humidity chamber. The weight change, compressive strength, flexural strength and carbonation depth of concrete bricks were measured. From the results, it was found that when subjected to CO2 curing, CO2 was absorbed at the level of 2.4 % of the weight of the specimen. The specimen incorporating ERS showed the highest carbonation depth, and satisfied KS F4004 standards for the concrete brick. Therefore, it is expected that the captured CO2 can be utilized in the CO2 curing process of concrete brick.
In order to standardize the chinese cabbage kimchi, the preparation method, kinds of ingredients and levels of the ingredients were determined by the statistical survey of literatures obtained from cooking books, scientific papers and kimchi manufacturing factory. The standardized ingredient kinds and ratio of chinese cabbage kimchi were $13.0{\pm}7.0$ of radish, $2.0{\pm}0.5$ of green onion, $3.5{\pm}0.8\;or\;2.5{\m}0.3$ of red pepper powder, $1.4{\pm}0.4$ of garlic, $0.6{\pm}0.3$ of ginger, $2.2{\pm}1.6$ of anchovy juice, and $1.0{\pm}0.3$ of sugar in the proportion of 100 salted chinese cabbage, and the final salt concentration was adjusted to 2.7% using salt. Red pepper powder level was quite different from the literature sources, so sensory evaluation, chemical properties and antimutagenic effect and growth inhibitory effect on human cancer cells of the kimchi samples were studied to decide the proper ratio of the red pepper powder as an ingredient. Red pepper powder 3.5% (average level for kimchi manufacturing factory) added kimchi was better in quality than red pepper powder 2.5% (average level for cooking books and scientific papers) added kimchi in sensory evaluation and chemical properties. The juice of red pepper powder 3.5% added kimchi showed not only the stronger antimutagenicity against aflatoxin $B_1$ in Salmonella typhimurium TA100 but also the higher inhibitory effect on the growth of AGS human gastric adenocarcinoma cells in SRB assay than that of red pepper powder 2.5% added kimchi. In conclusion, the standardized ratio of the ingredients was 13.0 radish, 2.0 green onion, 3.5 red pepper powder, 1.4 garlic, 0.6 ginger, 2.2 anchovy juice, 1.0 sugar, and 2.7 final salt concentration in the proportion of 100 salted chinese cabbage.
Paddy fields are apparently nonpoint source pollution and influence water environment. In order to improve water quality in rivers or lakes, to low nutrient load from paddy fields are required. To establish comprehensive plan to control agricultural non-point source pollution, it is imperative to get a quantitative evaluation on pollutants and pollution load from paddy fields. A field monitoring study was carried out to investigate the water balance and losses of nutrients from fields in Sumjin river basin. The size of paddy fields was 115 ha and the fields were irrigated from a pumping station. The observed total nitrogen loads from paddy fields were larger than those of the unit loads determined by Ministry of Environment data (MOE). It is because the nitrogen fertilization level at the studied field was higher than the recommended rate and the high irrigation and subsequent drainage amount. On the contrary, total phosphorus loads were less than those addressed by MOE since phosphorus fertilization level was lower than that of standard level. Therefore, it was found that fertilization, irrigation, and drainage management are key factors to determine nutrient losses from paddy fields. When the runoff losses of nutrients were compared to applied chemical fertilizer, it was found that 42 to 60% of nitrogen lost via runoff while runoff losses of phosphorus account for 1.3 to 7.6% of the total applied amount during the entire year.
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