• Title/Summary/Keyword: t-analysis

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Methylenetetrahydrofolate Reductase C677T Polymorphism and Cervical Cancer Risk: a Meta-Analysis

  • Guo, Li-Na
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2193-2197
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    • 2012
  • Background: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate, and the role of MTHFR C677T polymorphism in cervical carcinogenesis is still controversial. Method: We performed a meta-analysis of all relevant case-control studies that examined any association between the C677T polymorphism and cervical cancer risk. We estimated summary odds ratios (ORs) with their confidence intervals (CIs) to assess links. Results: Finally, 10 studies with a total of 2113 cervical cancer cases and 2804 controls were included. Results from this meta-analysis showed that significantly elevated cervical cancer risk was associated with the MTHFR T allele in the Asian population under conditions of two genetic comparison models (for TT vs. CC, OR = 1.37, 95%CI 1.00-1.87, P = 0.050; for TT vs. TC+CC: OR = 1.34, 95%CI 1.01-1.77, P = 0.039). However, there was no obvious association between the MTHFR C677T polymorphism and cervical cancer risk in the other populations. Conclusion: The MTHFR C677T polymorphism is associated with cervical cancer risk in Asians, while any possible link in the Caucasian population needs further studies.

Correlation Analysis of Water Quality According to Land Use Types of Reservoir Watershed (유역 토지이용과 저수지 수질의 상관관계 분석)

  • Youn, Dong-Koun;Chung, Sang-Ok
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2005.10a
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    • pp.614-619
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    • 2005
  • The object of this study was to presented regression equations for obtaining simply and quickly values of water quality items, BOD, COD, T-N, and T-P. Regression equations obtained to analyze relationships for water quality items to land use types in agricultural reservoir watersheds. In order to derive regression equations, a multiple linear regression analysis was used in this studying reservoirs. In this regression analysis, a independent values used land used types and dependent values used BOD, COD, T-N, T-P values in water quality items. The results showed that numbers of regression equation ranging above 0.90 in a multiple correlation coefficient (MCC) was not found, ranging from 0.70 to 0.90 in the MCC was 6, ranging from 0.40 to 0.70 in the MCC was 20, and ranging from 0.20 to 0.40 in the MCC was 4. The results of this study can be used as a basic information for evaluating simply and quickly water quality for proposing and designing steps in water quality policy.

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Revise the Value of Simulation on Thermal Performance Depending on Air-tightness Performance Classified by Opening Type of Windows (창의 개폐방식별 기밀성능에 따른 단열성능 시뮬레이션 보정치 산출)

  • Lee, Jin-Sung;Cho, Soo;Sohn, Jang-Yeul
    • Journal of the Korean Solar Energy Society
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    • v.28 no.4
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    • pp.68-75
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    • 2008
  • The purpose of this research is revise the value yield to compensate of measure the difference between computer simulation and the measurement value on the two methods which can calculates thermal performance. The way is need to understand about thermal performance, air tightness, simulations and comparisons of analysis to influence the value of each identified. The opening type of the windows and doors to be used at the analysis are T/T, L/S and SL Different condition of the windows and doors excluded except the opening type. Each of the four samples was selected by the way of opening. Result of the analysis of the difference between measurement and simulation are that T/T approach 5.3%, L/S approach 15.7%, SL approach 21% and the more air-tightness guarantees less difference of the numerical value. Each compensation value calculates by the correlation regression analysis and the air-tightness data. After the compensation of the resulting difference in T/T, L/S, SL indicate 5.4%, 2.5%, 1.0% respectively.

Reliability analysis of nuclear safety-class DCS based on T-S fuzzy fault tree and Bayesian network

  • Xu Zhang;Zhiguang Deng;Yifan Jian;Qichang Huang;Hao Peng;Quan Ma
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1901-1910
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    • 2023
  • The safety-class (1E) digital control system (DCS) of nuclear power plant characterized structural multiple redundancies, therefore, it is important to quantitatively evaluate the reliability of DCS in different degree of backup loss. In this paper, a reliability evaluation model based on T-S fuzzy fault tree (FT) is proposed for 1E DCS of nuclear power plant, in which the connection relationship between components is described by T-S fuzzy gates. Specifically, an output rejection control system is chosen as an example, based on the T-S fuzzy FT model, the key indicators such as probabilistic importance are calculated, and for a further discussion, the T-S fuzzy FT model is transformed into Bayesian Network(BN) equivalently, and the fault diagnosis based on probabilistic analysis is accomplished. Combined with the analysis of actual objects, the effectiveness of proposed method is proved.

Relationship of diploid East Aisan Taraxacum Wiggers using the capitulum morphological character (형태형질에 의한 동아시아산 민들레속 2배체 식물의 유연관계)

  • Lee, Kyung Hwa;Yang, Ji Young;Morita, Tatsuyoshi;Ito, Motomi;Pak, Jae-Hong
    • Korean Journal of Plant Taxonomy
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    • v.34 no.2
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    • pp.153-166
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    • 2004
  • Genus Taraxacum propagated through diploid sexual reproduction and polyploid agamospermy. The cluster analysis of Korean(2 species, 4 population), Japanese (2 species 4 taxa 6 population) and Taiwanese (1 species, 3 population) Taraxacum species using 15 measured capitulum morphological characters was conducted to study the speciation of diploid Taraxacum in East Asia. We measured 15 capitulum morphological characters including length of capitulum, length and shape of outer-involucre, corniculate appandage. Within one population, these characters were very various and were overlapped. The result of cluster analysis using morphological character showed that all species were clustered into four groups (Korean species & T. japonicum group, T. platycarpum subspecies group, T. platycarpum subsp. hodense group, T. formosanum group). Korean species, T. hallaisanense (diploid) and T. ohiwanum (diploid, triploid) were clustered into T. japonicum that was occurred in Kansai provinces of Japan. Therefore, we could infer that Korean species was closely related to Japanese T. japonicum of Japanese species.

T-RFLP Analysis of Microbial Community Structure in Leachate from Landfill Sites (폐기물매립장 침출수내 미생물군집 구조 해석을 위한 T-RFLP의 활용)

  • Yu, Jae-Cheul;Ishigaki, Tomonori;Kamagata, Yoichi;Lee, Tae-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.32 no.4
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    • pp.369-378
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    • 2010
  • Microorganisms are key-role player for stabilization of landfill sites. In order to evaluate the availability of T-RFLP(Terminal Restriction Fragment Length Polymorphism) for monitoring microbial community variations during stabilization of landfill sites, the phylogenic diversity of microbial community in the leachate from 4 different full-scale landfills was characterized by T-RFLP based on bacterial 16S rDNA. Main population of microbial community analyzed by T-RFLP was significantly similar with that of microbial community analyzed by clone library analysis. The results of T-RFLP analysis for main population of microbial community in the leachate from landfills with different landfill structures, waste types and landfill ages showed apparently different microbial diversity and structures. Therefore, long-term monitoring of microbial community in leachate from landfill sites by using T-RFLP is expected to be available for evaluation of landfill stability.

Benefit of Using Early Contrast-Enhanced 2D T2-Weighted Fluid-Attenuated Inversion Recovery Image to Detect Leptomeningeal Metastasis in Lung-Cancer Staging

  • Kim, Han Joon;Lee, Jungbin;Lee, A Leum;Lee, Jae-Wook;Kim, Chan-Kyu;Kim, Jung Youn;Park, Sung-Tae;Chang, Kee-Hyun
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.1
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    • pp.32-42
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    • 2022
  • Purpose: To evaluate the clinical benefit of 2D contrast-enhanced T2 fluid-attenuated inversion recovery (CE-T2 FLAIR) image for detecting leptomeningeal metastasis (LM) in the brain metastasis work-up for lung cancer. Materials and Methods: From June 2017 to July 2019, we collected all consecutive patients with lung cancer who underwent brain magnetic resonance image (MRI), including contrast-enhanced 3D fast spin echo T1 black-blood image (CE-T1WI) and CE-T2 FLAIR; we recruited clinico-radiologically suspected LM cases. Two independent readers analyzed the images for LM in three sessions: CE-T1WI, CE-T2 FLAIR, and their combination. Results: We recruited 526 patients with suspected lung cancer who underwent brain MRI; of these, we excluded 77 (insufficient image protocol, unclear pathology, different contrast media, poor image quality). Of the 449 patients, 34 were clinico-radiologically suspected to have LM; among them, 23 were diagnosed with true LM. The calculated detection performance of CE-T1WI, CE-T2 FLAIR, and combined analysis obtained from the 34 suspected LM were highest in the combined analysis (AUC: 0.80, 0.82, and 0.89, respectively). The inter-observer agreement was also the highest in the combined analysis (0.68, 0.72, and 0.86, respectively). In quantitative analyses, CNR of CE-T2 FLAIR was significantly higher than that of CE-T1WI (Wilcoxon signed rank test, P < 0.05). Conclusion: Adding CE-T2 FLAIR might provide better detection for LM in the brain-metastasis screening for lung cancer.

Comparative Genome analysis of the Genus Curvibacter and the Description of Curvibacter microcysteis sp. nov. and Curvibacter cyanobacteriorum sp. nov., Isolated from Fresh Water during the Cyanobacterial Bloom Period

  • Ve Van Le;So-Ra Ko;Mingyeong Kang;Seonah Jeong;Hee-Mock Oh;Chi-Yong Ahn
    • Journal of Microbiology and Biotechnology
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    • v.33 no.11
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    • pp.1428-1436
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    • 2023
  • The three Gram-negative, catalase- and oxidase-positive bacterial strains RS43T, HBC28, and HBC61T, were isolated from fresh water and subjected to a polyphasic study. Comparison of 16S rRNA gene sequence initially indicated that strains RS43T, HBC28, and HBC61T were closely related to species of genus Curvibacter and shared the highest sequence similarity of 98.14%, 98.21%, and 98.76%, respectively, with Curvibacter gracilis 7-1T. Phylogenetic analysis based on genome sequences placed all strains within the genus Curvibacter. The average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) values between the three strains and related type strains supported their recognition as two novel genospecies in the genus Curvibacter. Comparative genomic analysis revealed that the genus possessed an open pangenome. Based on KEGG BlastKOALA analyses, Curvibacter species have the potential to metabolize benzoate, phenylacetate, catechol, and salicylate, indicating their potential use in the elimination of these compounds from the water systems. The results of polyphasic characterization indicated that strain RS43T and HBC61T represent two novel species, for which the name Curvibacter microcysteis sp. nov. (type strain RS43T =KCTC 92793T=LMG 32714T) and Curvibacter cyanobacteriorum sp. nov. (type strain HBC61T =KCTC 92794T=LMG 32713T) are proposed.

Characteristics of Geomorphological Surface and Analysis of Deposits in Fluvial Terraces at Upper Reach of Soyang River (소양강 상류 하안단구의 지형면 특성과 퇴적물 분석)

  • 이광률
    • Journal of the Korean Geographical Society
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    • v.39 no.1
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    • pp.27-44
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    • 2004
  • Upper reach of Soyang River at the northernmost area around Taebaek Mountains in South korea is profitable area to understand paleo-environment during the Quaternary such as tectonic process and climate change in the Korean Peninsula. This study explained paleo-environment affect to channel development by geomorphic distribution and characteristics of terrace surfaces, and analysis of deposits at 58 fluvial terraces in upper reach of Soyang River. Fluvial terraces were classified from T1 to T6. Most terraces are distributed on the point bar in meandering channel and one side along river valley. Terraces tend to decrease in number and superficial dissection rate to be higher and channel slope to be steeper if it takes long time from T1 to 6. The paleo-channel of Soyang River is supposed to be stronger meandering in period of T2 than T3. The weathering rind of gravel is generally thicker in older terrace, however, differs by contents of water and air in deposits. Based on the data of stratigraphy, grain size analysis, pollen analysis and rubification index in deposit, formation age of T5 terrace in Soyang River are estimated in MIS(Marine Oxygen Isotope Stage) 10, and T2 terrace are estimated in MIS 6.

A Study on Ash Fusibility Temperature of Domestic Thermal Coal Implementing Thermo-Mechanical Analysis (TMA를 이용한 국내 발전용 탄의 용융점 변화에 대한 연구)

  • Lee, Soon-Ho;Lim, Ho;Kim, Sang Do;Jeon, Chung-Hwan
    • Korean Chemical Engineering Research
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    • v.52 no.2
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    • pp.233-239
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    • 2014
  • The slagging which generated from ash deposition on furnace wall and tube in boiler reduces the heat transfer efficiency and damages to safety of boiler. The slag flow behavior in boiler is affected by melting temperature which is related to ash compositions. In this study, the behavior of slag is researched by using ash fusibility test, called TMA (Thermo-Mechanical Analysis). The technique measures the percentage shrinkage as the function of temperature, T25%, T50%, T75%, T90%. These temperatures indicate different stages of melting. Then, the effect of ash chemical compositions measured from XRF (X-ray Fluorescence Spectrometer) to ash fusion temperatures is discussed. Among the chemical compositions, refractory and fluxing influence on ash fusibility is described. High levels of refractory component and limited amount of fluxing components ($Fe_2O_3$, $K_2O$, CaO) increase overall melting temperatures. High $SiO_2/Al_2O_3$ ratio decrease high melting temperatures (T75%, T90%). Meanwhile, the presence of reasonable levels of fluxing components reduces overall melting temperature. A presence of fluxing component such as $K_2O$ and CaO is found to decrease the T25% values significantly. From this research, it is possible to make a reasonable explanation and prediction of ash fusion characteristic from analysis of TMA results and ash chemical compositions.