• Korean Journal of Plant Taxonomy
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• v.44 no.1
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• pp.39-50
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• 2014

Phylogenetic positions of Sedirea and Neofinetia were addressed using the chloroplast matK and the nuclear ITS sequences. We also evaluate the usefulness of the makers for the identification of species and localities. Sedirea and Neofinetia form an independent monophyletic genus, respectively, in both matK and nuclear ITS trees. The sister genus of the Neofinetia was Vanda in both trees. In addition, our trees support the separate recognition of the Neofinetia from Vanda rather than the inclusion of Neofinetia into Vanda. The sister group of the Sedirea was (Dimorphorchis(Pteroceras(Saccolabiun+Phalaeonopsis))) clade. The Dimorphorchis was one of the most probable sister genus to the Sedirea. The sister group relationship between Sedirea and Aerides was suggested by their similar morphology, but not supported in molecular trees. The identification of species and localities of Neofinetia was possible using our two molecular markers. However, several pseudo-gene sequences are discovered from the public data base. In addition, the horizontal gene transfer of chloroplast genomes is frequent events in orchid hybrids. Therefore, we need a careful evaluation for the data prior to systematic use. Generation of sequence data from multiple accessions of a species may helpful to reduce these types of error.

• Journal of Korean society of Dental Hygiene
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• v.16 no.2
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• pp.173-183
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• 2016

Objectives: The purpose of the study is to investigate and analyzed the current status of a dental hygiene curriculum according to the dental hygienist competency. Methods: The study subjects were 59 courses in the department of dental hygiene in G University from April 1 to May 30, 2015. Except for liberal arts, 51 courses were finally selected and analyzed for the relationship between the curriculum and competency. For each course, systematic reviews were made by subject name, core competency, achievement goals, lecture hours, weekly themes, and learning goals. Three experts in the dental hygiene evaluated and analyzed the association of competency and goals. Results: Each course was operated by the goal from one to twenty two competencies of dental hygiene. Achieving one item of competency in a course required 13 hours on the average from minimum 2 hours to maximum 30 hours. More than 20 courses were operated and more than 900 hours were necessary for achieving the competency. The competency included the contents of 'Be able to utilize basic medical and dental knowledge in dental hygiene care and patient care' among the dental hygiene competencies. Conclusions: Competency based dental hygiene education will provide theoretical background for defining the identity of dental hygienist as a health care worker and to encourage professionals who contribute to the recognition of healthy society. Further research should be continued for improving the competency-based dental hygiene curriculum and education methods for implementing the curriculum within the paradigm of health care services.

• Journal of Food Hygiene and Safety
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• v.17 no.1
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• pp.45-54
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• 2002

Hazard Analysis Critical Control Point System (HACCP) is recognized worldwide as a science-based and systematic approach for food safety. This has been initiated to establish the HACCP system in Korean slaughterhouses by suggesting some of effective implementation ways. An awareness level survey using questionnaire for 124 owners and 363 employees of the slaughterhouses, and 170 government officers responsible for HACCP duties was performed. This study shows that only 34.7% of owners, 21.1% of employees, and 57.1% of government officers have good understanding of HACCP, but 93.5%, 88.9% and 93.6% respectively have the willingness of HACCP implementation. Major benefits in HACCP implementation in the slaughterhouse raised by respondents were improvement of hygiene level of the plant (54.1%), increase of meat sale (17.6%), pride of the production of safe meat for human consumption (9.6%) and increase of meat export (7.5%), while major obstacles were financial difficulties (33.2%), poor levels of the facilities and equipments in the plants (27.3%), poor level of personal hygiene (19.4%), and lack of understanding of HACCP (12.3%). The most urgent measures which respondents raised to implement HACCP system effectively in the slaughterhouses at the moment were the Improvement of levels of facilities and equipments in the plants (36.6%), the establishment of HACCP base through education and training (19%), special benefits to HACCP implementing plant (11.8%), and close relationship between government and the industry (10.3%). The present study shows some of effective ways to implement HACCP in slaughterhouses.

• Korean Journal of Health Education and Promotion
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• v.13 no.1
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• pp.90-116
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• 1996

The purpose of this study is to provide basic data for the children so as to avoid any accidents and to improve their health through a sound and safe living environment with safety education established through more systematic methods. For the study, the methods used include the questionnaires for collecting data which are distributed among 273 children from 3 to 6 years old. They live in three districts of Seoul (Kangnam and Kangbuk), Kyeonggido (Munsan and Ilsan) and Incheon. The children's general characteristics are investigated and the relationship between the accident-proneness prospects and their results are analyzed assuming that children's health is expected to have an effect on their safety. The findings of the study are as follows: 1. The accident-proneness prospect (for the living safety) has significant difference in sleeping habits and physically weak conditions(p<0.05). 2. The accident-proneness prospect (for the traffic safety) has no significant difference in accordance with the children's health condition. 3. Children's reasoning power has no significant difference in accordance with their health condition. 4. Children's movement speed non-significantly differs in accordance with their health condition. 5. Children's movement stability has a significant difference in accordance with their health conditions such as history of mild disease(p<0.05) and physical work capacity(p<0.05). 6. Children's attention power has no significant difference in accordance with their health condition. 7. Children's characteristic activities show a significant difference in accordance with their health history of mild disease(p<0.05). mental health(p<0.05). eating habits(p<0.05) and others (i.e. auditory abnormality and skin desease)(p<0.05). 8. General assessment of the APP test has no significant difference in accordance with their health condition. 9. The health conditions are a significant difference in the history of mild disease in accordance with sex(p<0.05) and whole family members(p<0.001). Also there are shown significant differences. in accordance with sex(p<0.05). in physical work capacity(p<0.05). Eye sight, blood circulation and skin condition show significant differences in accordance with residence(p<0.05) and whole family members(p<0.01). and the condition of eating habits appeared significant in accordance with age(p<0.05). Also, sleeping habits and physically weak conditions shows significant differences in accordance with age(p<0.001) and housing pattern(p<0.01), and others (i.e. auditory abnormality and skin desease) show significant differences in accordance with residence (p<0.001).

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3165-3172
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• 2012

Objective: Genetic polymorphisms in metabolic enzymes are associated with numerous cancers. A large number of single nucleotide polymorphisms (SNPs) in the CYP2D6 gene have been reported to associate with cancer susceptibility. However, the results are controversial. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to summarize the evidence for associations. Methods: Studies focusing on the relationship between CYP2D6 gene polymorphisms and susceptibility to cancer were selected from the Pubmed, Cochrane library, Embase, Web of Science, Springerlink, CNKI and CBM databases. Data were extracted by two independent reviewers and the meta-analysis was performed with Review Manager Version 5.1.6 and STATA Version 12.0 software. Odds ratios (ORs) with 95% confidence intervals (95%CIs) were calculated. Results: According to the inclusion criteria, forty-three studies with a total of 7,009 cancer cases and 9,646 healthy controls, were included in the meta-analysis. The results showed that there was a positive association between heterozygote (GC) of rs1135840 and cancer risk (OR=1.92, 95%CI: 1.14-3.21, P=0.01). In addition, we found that homozygote (CC) of rs1135840 might be a protective factor for cancer (OR=0.58, 95%CI: 0.34-0.97, P=0.04). Similarly, the G allele and G carrier (AG + GG) of rs16947 and heterozygote (A/del) of rs35742686 had negative associations with cancer risk (OR=0.69, 95%CI: 0.48-0.99, P=0.04; OR=0.60, 95%CI: 0.38-0.94, P=0.03; OR=0.50, 95%CI: 0.26-0.95, P=0.03; respectively). Conclusion: This meta-analysis suggests that CYP2D6 gene polymorphisms are involved in the pathogenesis of various cancers. The heterozygote (GC) of rs1135840 in CYP2D6 gene might increase the risk while the homozygote (CC) of rs1135840, G allele and G carrier (AG + GG) of rs16947 and heterozygote (A/del) of rs35742686 might be protective factors.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5761-5767
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• 2013

The potential correlation of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with hepatocellular carcinoma (HCC) susceptibility is ambiguous. Taking account of inconsistent results of previous meta-analyses and new emerging literatures, we conducted a meta-analysis covering 15 case-control datasets to evaluate the relationship. Relevant studies from Medline, Embase and CNKI were retrieved. A fixed-effect model or a random-effect model, depending on between-study heterogeneity, were applied to estimate the association between XRCC1 polymorphism Arg399Gln and HCC risk with the results presented as odds ratios (ORs) and 95% confidence intervals (95% CIs). In accordance with Hardy-Weinberg equilibrium, 15 studies with data for 6,556 individuals were enrolled in this systematic review. For overall HCC,thr XRCC1 polymorphism Arg399Gln was significantly associated with HCC susceptibility in a homozygote model as well as in a dominant model (G/G vs. A/A, OR=1.253, p=0.028; G/G+A/G vs. A/A, OR= 1.281, p=0.047, respectively), but not in a heterozygote model (A/G vs. A/A, OR=1.271, p=0.066) or a recessive model (G/G vs. A/G + A/A, OR= 1.049, p=0.542). Similar results were also observed on stratification analysis by ethnicity (A/G vs. A/A, OR=1.357, p=0.025; G/G vs. A/A, OR=1.310, p=0.011; G/G+A/G vs. A/A, OR= 1.371, p=0.013). However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified. No publication bias was found in this study. In conclusion, the XRCC1 Arg399Gln polymorphism contributes to HCC susceptibility. Due to the lack of studies in Western countries, further large-sample and rigorous studies are needed to validate the findings.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.12 no.6
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• pp.99-109
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• 2017

University learning for innovation places great importance on maximizing the creation of new opportunities. In other words, universities are carrying out a new meaning that entrepreneurship education should enable students to discover potential opportunities and play an important role in the development of new society and industry. However, current entrepreneurship education programs are being developed and are being developed from diverse perspectives on rapidly changing environments. However, there is a growing awareness of the necessity of developing more professional and systematic entrepreneurship education programs, and it is argued that the emphasis on necessity is not enough have. This study empirically analyzed the cognitive abilities that influence innovative behavior to create and realize innovative ideas and the usefulness of team-based learning that influences these factors. The results of empirical research showed that self-directed learning ability and problem solving ability had a positive effect on innovation behavior and problem solving ability had a positive effect on innovation behavior as a part of self-directed learning ability. Team-based learning in entrepreneurship education has been shown to be beneficial as a moderating effect on the relationship between problem-solving ability and self-directed learning ability and innovation behavior. In the case of four factors of team-based learning, Respectively. This study suggests the effectiveness and application of team-based learning method in entrepreneurship education.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.9
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• pp.1137-1143
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• 2010

This paper presents a fatigue design method for plug- and ring-type gas-welded joints, which takes into account the effects of welding residual stress. To develop this method, we simulated the gas-welding process by performing nonlinear finite element analysis (FEA) To validate the FEA results, numerically calculated residual stresses in the gas welds were then compared with experimental results obtained by the hole-drilling method. To evaluate the fatigue strength of plug- and ring-type gas-welded joints influenced by welding residual stresses, the use of stress amplitude $(\sigma_a)_R$, which includes the welding residual stress in gas welds, is proposed $(\sigma_a)_R$ on the basis of a modified Goodman equation that includes the residual stress effects. Using the stress amplitude $(\sigma_a)_R$ at the hot spot point of gas weld, the relations obtained as the fatigue test results for plug and ring type gas welded joints having various dimensions and shapes were systematically rearranged to obtain the $(\sigma_a)_R-N_f$ relationship. It was found that more systematic and accurate evaluation of the fatigue strength of plug- and ring-type gas-welded joints can be achieved by using $(\sigma_a)_R$.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.12
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• pp.543-548
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• 2017

In recent years, the importance of the safety of medical device software has been emphasized because of the function and role of the software among components of the medical device, and because the operation of the medical device software is directly related to the life and safety of the user. To this end, various standards have been set up that provide activities that can effectively ensure the safety of medical devices and provide their respective requirements. The activities that standards provide to ensure the safety of medical device software are largely divided into the development life cycle of medical device software and the risk management process. These two activities should be concurrent with the development process, but there is a limitation that the risk management requirements to be performed at each stage of the medical device software development life cycle are not classified. As a result, developers must analyze the association of standards directly to develop risk management activities during the development of medical devices. Therefore, in this paper, we analyze the relationship between medical device software development life cycle and risk management process, and extract risk management requirement items. It enables efficient and systematic risk management during the development of medical device software by mapping the extracted risk management requirement items to the development life cycle based on the analyzed associations.

• International Journal of Highway Engineering
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• v.3 no.2 s.8
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• pp.113-121
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• 2001

Among the currently available binder specifications, Superpave Performance Grade asphalt specification is regarded as a superior specification on its theoretical background as well as pavement performance relationship. Many difficulties are expected; however, for Superpave implementation in Korea because of heavy burden of equipment cost as well as lack of trained personnel in asphalt industry, which may too much barrier to overcome in Korean situation. As an effort to improve qualify of asphalt binder, recently, people discuss about a possibility of constituting a performance-based asphalt specification using rather easy-to-measure asphalt properties. The objective of this paper is to determine the possibility of constituting a performance-based asphalt specification using an empirical asphalt properties, such as penetration ring and ball softening point rather than using fundamental properties of asphalt. Nine straight asphalts, that covers entire straight asphalt from all Korean refineries, and eighteen modified asphalts that were modified from two modifiers were included in the study. An analysis was made through a comparison between empirical properties and Superpave PG criteria. This study concluded that it may possible to constitute a pseudo-Superpave-like specification using an empirical asphalt properties as a specification criteria. Therefore, more systematic research is needed to constitute the asphalt specification.