• Title/Summary/Keyword: synthetic method

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Studies on the Determination of Synthetic Food Colors (합성식용색소의 정량분석법에 관한 검토)

  • Om Ae-Son;Lee Heon-Ok;Shim Jae-Young;Shin Dong-Hwa;Kim Yong-Suk;Lee Young-Hwan;Bang Jeong-Ho;Shin Jae-Wook;Lee Tal-Soo;Hong Ki-Hyoung;Park Sung-Kwan;Choi Duck-Jang;Kim Hee-Yun
    • Journal of Food Hygiene and Safety
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    • v.20 no.2
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    • pp.73-76
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    • 2005
  • Center for Food Standard Evaluation, Korea Food and Drug AdministrationThis study was performed to compare analytical methods of nine synthetic food colors and six food color lakes in Korea, Japan, Joint FAO/WHO Expert Committee of Food Additives (JECFA), and USA. The experimental protocol of this study consists of three parts: titration method with titanium chloride, gravimetric and spectrophotometric method. To measure the total contents of food colors, Korea and Japan used titration method with titanium chloride, USA used the average value of titration method with titanium chloride equipped with Kipp generator and spectrophotometric method. Also, JECFA used titration method with titanium chloride equipped with KiPP generator. However, All the low organizations used gravimetric method to measure the total content of coloring matter on Food Red No.3. Although all organizations use various methods for analysis of coloring matters, total contents of coloring matter on food colors tested fell into the standard showing $85.08-96.40\%$ in synthetic food colors and $10.00-36.86\%$ in food color lakes.

Synthesis of Radar Measurements and Ground Measurements using the Successive Correction Method(SCM) (연속수정법을 이용한 레이더 자료와 지상 강우자료의 합성)

  • Kim, Kyoung-Jun;Choi, Jeong-Ho;Yoo, Chul-Sang
    • Journal of Korea Water Resources Association
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    • v.41 no.7
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    • pp.681-692
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    • 2008
  • This study investigated the application of the successive correction method(SCM), a simple data assimilation method, for synthesizing the radar and rain gauge data. First, the number of iteration and influence radius for the SCM application were decided based on their sensitivity analysis. Also, for the evaluation of synthetic rainfall, the distributed rainfall field using the dense rainfall gauge network was assumed to be the true one. The synthetic rainfall field based on the SCM was also compared quantitatively with the one based on the co-Kriging frequently used nowadays. As the results, the SCM, a simple and economical data assimilation method, was found to secure the accuracy and statistical characteristics of the co-Kriging application.

Algorithm for Predicting Functionally Equivalent Proteins from BLAST and HMMER Searches

  • Yu, Dong Su;Lee, Dae-Hee;Kim, Seong Keun;Lee, Choong Hoon;Song, Ju Yeon;Kong, Eun Bae;Kim, Jihyun F.
    • Journal of Microbiology and Biotechnology
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    • v.22 no.8
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    • pp.1054-1058
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    • 2012
  • In order to predict biologically significant attributes such as function from protein sequences, searching against large databases for homologous proteins is a common practice. In particular, BLAST and HMMER are widely used in a variety of biological fields. However, sequence-homologous proteins determined by BLAST and proteins having the same domains predicted by HMMER are not always functionally equivalent, even though their sequences are aligning with high similarity. Thus, accurate assignment of functionally equivalent proteins from aligned sequences remains a challenge in bioinformatics. We have developed the FEP-BH algorithm to predict functionally equivalent proteins from protein-protein pairs identified by BLAST and from protein-domain pairs predicted by HMMER. When examined against domain classes of the Pfam-A seed database, FEP-BH showed 71.53% accuracy, whereas BLAST and HMMER were 57.72% and 36.62%, respectively. We expect that the FEP-BH algorithm will be effective in predicting functionally equivalent proteins from BLAST and HMMER outputs and will also suit biologists who want to search out functionally equivalent proteins from among sequence-homologous proteins.

Displacements, damage measures and response spectra obtained from a synthetic accelerogram processed by causal and acausal Butterworth filters

  • Gundes Bakir, Pelin;Richard, J. Vaccaro
    • Structural Engineering and Mechanics
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    • v.23 no.4
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    • pp.409-430
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    • 2006
  • The aim of this study is to investigate the reliability of strong motion records processed by causal and acausal Butterworth filters in comparison to the results obtained from a synthetic accelerogram. For this purpose, the fault parallel component of the Bolu record of the Duzce earthquake is modeled with a sum of exponentially damped sinusoidal components. Noise-free velocities and displacements are then obtained by analytically integrating the synthetic acceleration model. The analytical velocity and displacement signals are used as a standard with which to judge the validity of the signals obtained by filtering with causal and acausal filters and numerically integrating the acceleration model. The results show that the acausal filters are clearly preferable to the causal filters due to the fact that the response spectra obtained from the acausal filters match the spectra obtained from the simulated accelerogram better than that obtained by causal filters. The response spectra are independent from the order of the filters and from the method of integration (whether analytical integration after a spline fit to the synthetic accelerogram or the trapezoidal rule). The response spectra are sensitive to the chosen corner frequency of both the causal and the acausal filters and also to the inclusion of the pads. Accurate prediction of the static residual displacement (SRD) is very important for structures traversing faults in the near-fault regions. The greatest adverse effect of the high pass filters is their removal of the SRD. However, the noise-free displacements obtained by double integrating the synthetic accelerogram analytically preserve the SRD. It is thus apparent that conventional high pass filters should not be used for processing near-fault strong-motion records although they can be reliably used for far-fault records if applied acausally. The ground motion parameters such as ARIAS intensity, HUSID plots, Housner spectral intensity and the duration of strong-motion are found to be insensitive to the causality of filters.

A Study on Improved Synthetic Utilization for Real-Time Aperiodic Tasks Scheduling (실시간 비주기 태스크 스케줄링을 위한 개선된 합성 이용율에 관한 연구)

  • Moon, Seok-Hwan;Kim, In-Guk
    • Journal of Digital Contents Society
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    • v.9 no.3
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    • pp.441-448
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    • 2008
  • Recently, several algorithms for scheduling aperiodic tasks have been proposed. Among them, Abdelzaher et al proposed an algorithm to determine the schedulability of aperiodic tasks, and proved that the aperiodic tasks are schedulable if the upperbound of synthetic utilization is less than or equal to $\frac 1{1+\sqrt{1/2}}{\approx}0.59$. But this algorithm has a drawback in that if some tasks, even though they are completed and have no more execution times, are included in the current invocation set, their execution times and deadlines are added to the synthetic utilization. This may lead to a problem in which actually schedulable tasks are decided not to be schedulable. In this paper, we recognize the above mentioned problem and propose an improved synthetic utilization method that can be used to schedule aperiodic tasks more efficiently.

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Facile Synthesis of 5-Hydroxy-3-pyrrolin-2-ones from Morita-Baylis-Hillman Adducts

  • Lim, Cheol-Hee;Kim, Sung-Hwan;Kim, Jae-Nyoung
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1622-1626
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    • 2012
  • An efficient synthetic method of various 5-hydroxy-3-pyrrolin-2-one derivatives has been developed starting from the MBH adducts. In addition, some synthetic applicability of the prepared 5-hydroxy-3-pyrrolin-2-ones was demonstrated including the synthesis of lactam-fused tetrahydroisoquinolines.

Comparision of the Blood Concentration of Ampicillin and Lysinomethylene Ampicillin in Man (Ampicillin과 Lysinomethylene Ampicillin의 혈중농도비교(血中濃度比較))

  • Kim, Johng-Kap;Kim, Young-Il;Kim, Bong-Hee
    • Journal of Pharmaceutical Investigation
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    • v.10 no.3
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    • pp.1-4
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    • 1980
  • In order to increase the solubility and antibacterial activity of ampicillin, the lysinomethylene ampicillin trihydrate was synthesized. The blood concentrations of ampicillin trihydrate and synthetic lysinomethylene ampicillin trihydrate were determined in 10 healthy male volunteers by using large plate method with Sarcina lutea ATCC 9341. The mean blood concentration of synthetic lysinomethylene ampicillin trihydrate was higher ca. 1.3 times than that of ampicillin trihydrate in 10 test subjects after oral administration.

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TRV Pattern Classification and Parameter Calculation Method for Double-Frequency Synthetic Test Circuit (2중주파 합성시험회로의 TRV 패턴 분류 및 파라미터 계산 방법)

  • Lee Yong Han
    • Proceedings of the KIEE Conference
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    • summer
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    • pp.587-589
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    • 2004
  • In this paper analytical pattern classification of TRV waves created by double-frequency synthetic test circuit was proposed. According to the classified patterns of the TRV wave, calculation methods of 3 reference lines and 4 parameters characterizing the TRV wave wire proposed. These methods can be utilized to optimize test facility and to standardize test quality.

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A Novel Synthetic Route to 11-Deoxyanthracycline AB Synthons

  • Kim, Hee-doo;Park, Sang-Ae;Jew, Sang-Sup
    • Archives of Pharmacal Research
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    • v.17 no.4
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    • pp.249-255
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    • 1994
  • An efficient synthetic method for 11-deoxyanthracycline AB synthons is described. A verstile key intemediate vinyl bromide 3 was prepared from 5- methodxy-1-tetralone in three steps, and then was converted to the allylic alcohols 4 and 8 which, in tum, fumished highly fuctionalized AB synthons 7 and 12, respectively, via sequential epoxidation-reduction-protection processes.

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Efficient Synthesis of Nucleoside Phosphonates using Olefin Cross-Metathesis

  • Quan, Ling-Lin;Kim, Ai-Hong;Kooh, Dae-Ho;Ko, Ok-Hyun;Hong, Joon-Hee
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.173.3-173.3
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    • 2003
  • In recent years, olefin cross-metathesis (CM) has emerged as a powerful and convenient synthetic technique in organic chemistry; however, as a general synthetic method, CM has been limited by the lack of predictability in product selectivity and stereoselectivity. A number of excellent studies have recently appeared in the literature which have shown that with the correct catalyst and reaction conditions CM can be used to access a variety of di-and trisubstituted olefinic products in moderate to high yield with good E/Z ratios. (omitted)

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