• 대한임상독성학회지
• /
• 제9권2호
• /
• pp.95-100
• /
• 2011

Purpose: Ingestion of puffer fish can be poisonous due to the presence of potent neurotoxins such as tetrodotoxin (TTX) found in its tissues. There are few clinical reports related to TTX. We performed this study to evaluate the clinical characteristics of TTX poisoning. Methods: We conducted a retrospective study of the 41 patients diagnosed with TTX poisoning who visited the Seoul Asan medical center from July 2004 and December 2010. A review of patients' electronic medical records and patient telephone interviews were conducted. Diagnosis of TTX poisoning was confirmed by observing the casual link between puffer fish consumption and the development of typical TTX intoxication symptoms. Results: The mean age of the patients included in the study was 46.6 years. The highest incidence of intoxication was observed in patients in their 50s (10 patients). Seasonal distribution of intoxication events included 10 in spring, 7 in summer, 10 in fall, and 14 in winter. In most cases, symptoms occurred within 1 hour of ingestion. A wide range of symptoms were associated with puffer fish ingestion affecting multiple body systems including neuromuscular (27 patients), gastrointestinal (19 patients), and cardiopulmonary/vascular (19 patients). All patients were treated with symptomatic and supportive therapy and recovered completely, without sequelae, within 48 hours. In three cases, ventilator support was required. Conclusion: TTX poisoning is not seasonally related, and patients admitted to the emergency room were observed with a wide range of symptoms. Where TTX poisoning is diagnosed, supportive therapy should be performed. Early intubation and ventilation is important, especially is cases of respiratory failure.

• 대한한방소아과학회지
• /
• 제28권4호
• /
• pp.30-44
• /
• 2014

Objectives By analyzing data of the pediatric patients who had visited the emergency room of the oriental medical hospital, we can understand their characteristics and diseases. The purpose of this study was to introduce the excellence of the Oriental medicine, to develop various treatments, and to revitalize pediatric emergency care at the oriental medical hospital. Methods The study was composed of 334 pediatric patients who had visited the emergency room of the ${\bigcirc}{\bigcirc}$ university oriental hospital from January 2011 to December 2013. Results 1. It has showed that between 7 to 12 years old patients (27.8%) were the most common age populations. 2. The number of pediatric patients was increased during February. According to the weekly distribution data, the number of pediatric patients who had visited on Sunday was the highest (28.7%). Also, the number of pediatric patients who had visited the ER between 21 to 24 hours (29.0%) was the highest. 3. The two major reasons for inpatient hospitalization were digestive and nerve-related symptoms. Nerve-related symptoms were the most common in infants while digestive symptoms were the most common in other child development stages. 4. The duration of time interval from the onset of symptoms to the ER visit was most commonly within 6 hours (50.3%). An acupuncture and herbal medication treatment (70.1%) were the most common medical treatments. The majority of the pediatric patients (95.5%) were discharged after their medical treatments. Conclusions A serious acute illness was not the most common reason for the ER visit among the pediatric patients. The most common disease states that have preferred to be treated with the oriental medicine were dyspepsia, crying, facial palsy, and ankle sprain. We have to introduce the excellence of the oriental medicine. We also need to try developing other treatments such as magnetic acupuncture, aromatherapy, and revitalizing pediatric emergency care at the oriental medical hospital.

• 한국한의학연구원논문집
• /
• 제14권2호
• /
• pp.47-66
• /
• 2008

Background: It is insufficient information that are syndrome differentiations and detail symptoms in Korean. Methods: 19 traditional korean medical agencies collected 190 cases with vital sign, body measurement, patient own symptoms report and doctor diagnosis. And then we analyzed general distributions and comparisons of deficiency and non-deficiency. Results: The most past histories, in order, were the arthritis(20%), gastroenteropathy, hypertension, anemia, diabete mellitus. In chief complains, musculoskeletal occupies 60 percent of the total, and digestive system, head in order. In the syndrome differentiation, it appeared deficiency, spleen, Qi deficiency in order. Age(p=0.000), systolic blood pressure(p=0.044) and the waist-hip ratio(p=0.000) was significantly higher in the deficiency group compared with non-deficiency group. Patients with condition which dislikes the wind and with anxiety and with amazing and fear(驚恐) were significantly more in deficiency group(p=0.029, p=0.017, p=0.044). Conclusions: These statistics are continually revised report and it will be reported comparison of several syndrome differentiations and therapeutic effects by treatment methods.

• Restorative Dentistry and Endodontics
• /
• 제28권4호
• /
• pp.303-313
• /
• 2003

It has been documented that periodontopathic bacteria are also implicated in endodontic infections. 168 rDNA gene-directed PCR was to examine the prevalence of periodontopathic bacteria including Actinobacillus actinomycetemcomitans (Aa), Prevotella intermedia (Pi), Prevotella nigrescens (Pn), Porphyromonas gingivalis (Pg), Porphyromonas endodontalis (Pe), and Treponema denticola (Td) in the root canals of 36 endodontically infected teeth having apical lesions with or without clinical symptoms like pain, swelling, and fistula. 1. In 36 infected root canals, most frequently detected bacterial species was Pg (61.1%), followed by Td (52.8%) and Pe (38.9%). 2. Of 36 infected root canals, Aa was detected in 6 canals (16.7%) of the teeth, all of which showed clinical symptoms. 3. Of 36 infected root canals, Pi and Pn were found in 4 03.9%) and 5 (33.3%), respectively. Notably, prevalence of Pn in the symptomatic teeth was 50.0%. 4. One of black-pigmented anaerobic bacteria (BPB) including Pi, Pn, Pe, and Pg was detected in all of the teeth that showed pain or especially swelling but not fistula. It was, however, found that prevalence of BPB in the asymptomatic teeth or the teeth with fistula was only 40%. 5. Pe and Pg were detected in the teeth regardless of the presence or absence of symptoms. 6. Td was detected in the teeth regardless of the presence or absence of symptoms. High prevalence of BPB in the symptomatic teeth but low in the asymptomatic teeth suggests that BPB may play an important role in the pathogenesis of periapical lesions.

• 사상체질의학회지
• /
• 제13권1호
• /
• pp.109-118
• /
• 2001

1. The purpose of this study This study was performed on the basis of clinical consideration about rhinitis patients who suffered from sneeze, rhinorrhea, rhinocleisis and etc. And we checked the clinical inclination of this disease and the characteristic treatments of Sasang Constitutional Medicine. 2. The method of this study For 17 months from October in 1999 to April in 2001 we selected outpatients who had consulted for rhinitis more than twice in the department of the Sasang Constitution of the Bundang Oriental medical hospital, Dongguk University, and 31 of those were confirmed of their course of treatment. From their medical records and history, we learned the general characterisics and patterns of rhinitis, and the qualities and effects of its various treatment. 3. The result of this study The result were as follows ; 1) The rate of patients who have had the symptoms over the two years was 74.2%. 2) In the distribution of chief symptoms, sneeze occupied 80.6% of all appealed symptoms, rhinocleisis 77.4%, rhinorrhea 71.0%, intranasal pruritus 54.8%, postnasal drip 16.1%, orderly. 3) The treatment period was about 30days. The method of treatment was the Herb-med Tx, acupuncture Tx and etc. The herb-med ingestion was about two times in that period. 4) On the effect of treatment, Sneeze and rhinocleisis were improved. 5) The symptoms of rhinitis was more depravated by fatigue and stressful condition than weather condition. This result shows that the improvement of general condition has an effect on the rhinitis treatment.

• 대한한방내과학회지
• /
• 제21권1호
• /
• pp.135-145
• /
• 2000

Objective : This study has been made to analysis of clinical type of vertigo prodromic Cerebral Vascular Disease in stroke patients who admitted to sangji oriental hospital department of circulatoty internal medicine in the period from July. 1999 to October 1999. Methods : A Questionaire was done after explanationin details to patients and agreement of patients. The inquire was done as follows. Sex and age, risk factor of stroke, type of stroke, existence of vertigo last three years before stroke attack, the beginning age of vertigo and period of prevalence, frequency, continuance time of vertigo, predilection season and time, factor of causing vertigo, accompanying symptoms of vertigo, severity of vertigo. Result and Conclusion : The existence of Rotation sense(Rotation group and non-Rotation group) and the type of Stroke is no difference significantly but the Rotation vertigo group and non-Rotation vertigo group is difference significantly in distribution. The sixties in age of vertigo attack, previous vertigo before 3 year Stroke attack, irregular in predilection season of vertigo, have a high frequency significantly in distribution and previous period of vertigo has no significantly difference in distribution. One or two per a month in frequency of vertigo, below 5 minute in continuance time of vertigo, irregular in predilection time of vertigo, stand up and sit down in causing vertigo position have a high frequency significantly in distribution.

• 대한한의학회지
• /
• 제17권2호
• /
• pp.418-426
• /
• 1996

Clinical studies were done 23 peoples who were treated with the auricular acupuncture therapy to the hypertension in the Dept. of the Acupuncture and Moxibution Hospital of Oriental Medicine in Won Kwang University. The following results have obtained. 1. Distribution of sex: male (52.0%), female (48.0%), 2. Distribution of age: 50s age group (30.0%), 70s(26.0%), 40s or 60s(22.0%). 3. Distribution of occupation: housewife (26.0%), farmer or commerce(22.0%), unemployed(13.0%), 4. Causes of illness: unknown origin(61.0%), stress(17.0%), drinking (13.0%), 5. Distribution according to symptom: headache(57.0%), non-symptom(17.0%), dizziness(9.0%). 6. Duration of onset: 3-5 years(26,0%), unknown(17.0%), 6 months, 5-10 years or 10 years (13.0%). 7. Cure rate of auricular acupuncture treatment according to differentiation symptoms: HLY(43.0%), DLK(30.0%), DYY(13.0%), HYD(9.0%). 8. Result grade on $pr{\`{e}}-freatment$ of auricular acupuncture: Grade I(4.0%), GradeII(52.0%), Grade III(43.0%). Result grade on post-treaftment auricular acupuncture: Grade O(48.0%), Grade I(26.0%), Grade II(26.0%).

• 대한간호학회지
• /
• 제23권4호
• /
• pp.569-584
• /
• 1993

This study was done to verify validity of nursing diagnoses related to difficulty in respiratory function. First, content validity was examined by an expert group considering the etiology and the signs / symptoms of three nursing diagnoses - ineffective airway clearance, ineffective breathing pattern, impaired gas exchange. Second, clinical validity was examined by comparing the frequencies of the etiologies and signs / symptoms of the three nursing diagnoses in clinical case studies with the results of the content validity. This study was a descriptive study. The sample consisted of 23 experts (professors, head nurses and clinical instructors) who had had a variety of experiences using nursing diagnoses in clinical practice, and 102 case reports done by senior student nurses of the college of nursing of Y-university. These reports were part of their clinical practice in the ICU. The instrument used for this study was a checklist for etiologies and signs and symptoms based on the literature, Doenges and Moorhouse (1988), Kim, McFarland, McLane (1991), Lee Won Hee et al. (1987), Kim Cho Ja et at. (1988). The data was collected over four month period from May 1992 to Aug. 1992. Data were analyzed using frequencies done with the SPSS / PC＋ package. The results of this study are summarized as follows : 1. General Characteristics of the Expert Group A bachelor degree was held by 43.5% and a master or doctoral degree by 56.5% of the expert group. The average age of the expert group was 35.3 years. Their average clinical experience was 9.3 years and their average experience in clinical practice was 5.9 years. The general characteristics of the patients showed that there were more women than men, that the age range was from 1 to over 80. Most of their medical diagnoses were diagnoses related to the respiratory. system, circulation or neurologic system, and 50% or more of them had a ventilator with intubation or a tracheostomy. The number of cases for each nursing diagnoses was : · Ineffective airway clearance, 92 cases. · Ineffective breathing pattern, 18 cases. · Impaired gas exchange, 22 cases. 2. The opinion of the expert group as to the classification of the etiology, and signs and symptoms of the three nursing diagnoses was as follows : · In 31.8% of the cases the classification of etiology was clear. · In 22.7%, the classification of signs and symptoms was clear. · In 17.4%, the classification of nursing interventions was clear. 3. In the expert group 80% or mere agreed to ‘dysp-nea’as a common sign and symptom of the three nursing diagnoses. The distinguishing signs and symptoms of (Ineffective airway clearance) were ‘sputum’, ‘cough’, ‘abnormal respiratory sounds : rales’. The distinguishing sings and symptoms of (Ineffective breathing pattern) were ‘tachypnea’, ‘use of accessory muscle of respiration’, ‘orthopnea’ and for (Impaired gas exchange) it was ‘abnormal arterial blood gas’, 4. The distribution of etiology, and signs and symptoms of the three nursing diagnoses was as follows : · There was a high frequency of ‘increased secretion from the bronchus and trachea’ in both the expert group and the case reports as the etiology of ineffective airway clearance. · For the etiologies for ineffective breathing pat-tern, ‘rain’, ‘anxiety’, ‘fear’, ‘obstructions of the tract, ca and bronchus’ had a high ratio in the ex-pert group and ‘decreased expansion of lung’ in the case reports. · For the etiologies for impaired gas exchanges, ‘altered oxygen -carrying capacity of the blood’ and ‘excess accumulation of interstitial fluid in lung’ had a high ratio in the expert group and ‘altered oxygen supply’ in the case reports. · For signs and symptoms for ineffective airway clearance, ‘dyspnea’, ‘altered amount and character of sputum’ were included by 100% of the expert group. ‘Abnormal respiratory. sound(rate, rhonchi)’ were included by a high ratio of the expert group. · For the signs and symptoms for ineffective breathing pattern. ‘dyspnea’, ‘shortness of breath’ were included by 100% of the expert group. In the case reports, ‘dyspnea’ and ‘tachypnea’ were reported as signs and symptoms. · For the sign and symptoms for impaired gas exchange, ‘hypoxia’ and ‘cyanosis’ had a high ratio in the expert group. In the case report, ‘hypercapnia’, ‘hypoxia’ and ‘inability to remove secretions’ were reported as signs and symptoms. In summary, the similarity of the etiologies and signs and symptoms of the three nursing diagnoses related to difficulty in respiratory function makes it difficult to distinguish among them But the clinical validity of three nursing diagnoses was established through this study, and at last one sign and symp-tom was defined for each diagnosis.

• 한국어병학회지
• /
• 제18권1호
• /
• pp.29-37
• /
• 2005

스쿠티카섬모충이 사육중인 자주복에 침입하였을 때 감염어의 외부증상, 행동특성 및 피부, 아가미 그리고 혈관내 충체의 분포 양상을 조사하였다. 스쿠티카섬모충에 감염된 개체는 초기에 체색 변화나 유영행동 등의 외부증상을 인지할 수 없었으나, 몸체에 감염부위가 병리적인 진행에 따라 표피와 지느러미에 발적과 부식, 그리고 궤양증상을 보였다. 또한 감염어는 정상개체와 달리 무리에서 이탈하여 선회 또는 저면에 멈춰 있거나 수면 위로 입올림 하였으며, 일부 개체에서는 돌발적인 유영도 보였다. 사육중인 자주복에 침입한 스쿠티카섬모충은 타원형으로 크기가 20-40 ${\mu}m$ 범위였고, 몸체의 미부에 수축포와 10-12 ${\mu}m$되는 하나의 긴 섬모가 개재되어 있으며, 생식방법은 이분열로 증식하여 형태분류학적인 측면에서 막구충아강 채찍섬모충목의 특색을 나타내었다. 아가미에 스쿠티카섬모충이 감염된 경우에는 아가미 새판상피의 비대로 새엽이 곤봉화 되는 병리적 현상이 있었다. 혈관 속에 침입한 스쿠티카섬모충들은 혈관의 직경 크기에 따라 1-2마리에서 많게는 9-10마리씩 산재하였고, 그들 중 일부 개체에서 적혈구 세포를 섭취한 스쿠티카섬모충이 관찰되었다.

• 대한후두음성언어의학회지
• /
• 제23권1호
• /
• pp.18-20
• /
• 2012

Over the last 30 years or so, it has been recognized that neurologic disorders could impair laryngeal function, and that neurogenic etiology could be discerned frequently. This has led collaborations between laryngologists and neurologists and focus on the management of neurogenic dysfunction of the larynx and pharynx, including central and peripheral disorder. The author introduced anatomical structure, nerve distribution and neurophysiology of the larynx for understanding its basic functions. The symptoms, diseases from laryngeal dysfunction and the development of diagnosis and management were also discussed.