• Research in Community and Public Health Nursing
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• v.9 no.2
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• pp.396-409
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• 1998

The purpose of this study is to inquire into the degree of health promotion activity of university students, and to confirm the general factors of health promotion behavior in order to offer basic data for a nursing strategy to improve health promotion behavior. For this research, data was collected from university men and women through questionnaires from February 18 to March 20 in 1998. The author develop a measuring instrument on the basis of related reviews of health promoting behavior in the prevention of chronic disease, as well as accounting for demographic factors, biological factors, and circumstanctial factors. The content validity of the instrument was authenticated by two professors of the science of nursing,. and the reliability was confirmed by a 'cronbach' ${\alpha}'$ after moditying the content through a pre-test on 30 students. 475 persons were analyzed in terms of an average, percentage, t-test, ANOVA by 'SPSS-PC'. The analyzed data was the following. 1. The acting degree of health promoting behavior was 3.26 point out of 6. Among the sub-levels of health promoting behavior, the order of importance was the following. self-actualization (4.62), interpersonal(4.60), stress management (4.0l), nutrition(3.68), responsibility(3.1l), liquid and cigaretles ues(2.85), and exercise (2.33). 2. The differences in health promoting behavior according to subject's general character were the following. Age(F=6.012, p=.003), major (F=7.243, P=.000), sex(t=7.60, P=.000), religion(F=2.454, p=.045), living status(F= 2.849, p=.024), health concern of parents(F= 7.596, P=.000), taking health programs(F= 2.710, p =.007), case history of the family( t = -1.980, p=.048). Health promoting behavior is affected by a higher age, majoring in the social sciences, having religion, male, living in the relatives' home, having to take health programs and a higher health concern of the parents. Suggestions: 1. The degree of health promoting behavior appears low in this study. It is crucial, therefore, to develop a health program to improve health promoting behavior and to study how to center the daily health life of students.

• Journal of agricultural medicine and community health
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• v.42 no.3
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• pp.155-167
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• 2017

Objectives: The purpose of this study was to examine the performances and limitations of health community building project of 148 village in Gangbuk-gu, Seoul on community health organization perspective. Methods: we conducted a qualitative study using both a systematic review of this project and in-depth interviews with the operators who had worked for the project from January 2012 to December 2012. Results: In this project, activists worked by gathering the opinions of the residents and focusing on their growth. The residents themselves established a community health care plan. Based on social determinants of health, they continued projects to solve residents' needs. A variety of programs were activated by providing a health cafe, which was an alternative public participation health promotion space that was not a clinic or a public health center. As the various entities gathered, there were difficulties related to interests and role sharing, and there were limitations such as the fact that the performance and limit of the pilot project could not be clearly predicted beforehand. Conclusions: This case suggested that new possibility of health and medical movement, approaching health issues by the way of community organization principle. Through the health community building project as community health organization perspective is expanded, health promotion effect will be created in the whole society.

• 한국노년학
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• v.29 no.1
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• pp.37-50
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• 2009

The purpose of the present study was to develop a community-based intensive health care program for the community dwelling elderly to strength their functional status and to verify the effect on their geriatric syndrome. A one-group pretest-posttest design was used for the study. A total of 69 frail elderly, who lived in the area within 20 minutes by car, were committed themselves to the day care center(Sangikjae), and had the ability of verbal communication were selected from G city in Kyunggi province. The participants completed a set of questionnaires to measure the sub-score of frailty, fall, urinary incontinence, malnutrition, and mild cognitive disorder domain, using the Otasha-Kensin through the physical examinations and interviews. After 4 weeks of intervention, the outcome was measured to evaluate the effects of the program, and the data obtained were analyzed using descriptive statistics, paired t-test and McNemar test. The results showed that the sub-score of frailty, fall, urinary incontinence, and malnutrition domain were statistically significantly decreased after intervention except those of urinary incontinence and mild cognitive disorder domain, implying that the risk of frailty, fall, and malnutrition was decreased. These findings indicated that community-based the intensive health care program is effective for relieving geriatric syndrome of the community dwelling elderly.

• Korean Journal of Environmental Biology
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• v.41 no.3
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• pp.256-265
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• 2023

Chlorothalonil is continuously introduced into the marine environment and has significant toxic effects on various marine organisms, however, research on its effect on seaweed is limited. Therefore, we analyzed the impact of chlorothalonil on the early life stages of major aquaculture species in Korea, Undaria pinnatifida. U. pinnatifida female gametophytes were exposed to different concentrations of chlorothalonil (0, 0.03, 0.05, 0.10, 0.20, and 0.40 mg L^-1), and their survival rate and relative growth rate were analyzed. The no observed effect concentration (NOEC), lowest observed effect concentration (LOEC), and median lethal concentration (LC50) for female gametophyte survival were determined as 0.05, 0.10, and 0.141(0.121-0.166)mg L^-1. NOEC, LOEC, and median effective concentration (EC50) for relative growth rate were 0.10, 0.20, and 0.124 (0.119-0.131) mg L^-1. Therefore, female gametophytes of U. pinnatifida are expected to experience toxic effects at concentrations above 0.05-0.10 mg L^-1 of chlorothalonil. These research findings are anticipated to serve as crucial reference data for evaluating the effects of chlorothalonil on the health of U. pinnatifida in the early life stages.

• Journal of muscle and joint health
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• v.16 no.1
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• pp.66-79
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• 2009

Purpose: The purpose of this study was to analyze the relationship between rehabilitation motive and social support perceived by spinal cord injury patients. Method: Data were collected by the questionnaires from 83 patients with spinal cord injury in a hospital. It was analyzed using descriptive statistics, t-test, ANOVA and Peason's correlation coefficients. Result: The social support score was 3.51 of 5 in average. The connectedness of subordinate portion was the highest as 3.57. The rehabilitation motive was 2.93 of maximum 4.00 in average. Among sub-dimensions of the rehabilitation motive, the mean score of change oriented motivation was 3.27 as the highest. The higher the direct support, the higher the indirect support(r=.663, p=.000). The higher the rehabilitation motive, the higher the direct(r=.282, p=.010) and indirect support(r=.397, p=.000). Conclusion: According to this study, the social support had the significant relationship with the rehabilitation motive. The social support was the key factor to enhance the rehabilitation motive psychologically. Finally, there is a need to develop the nursing intervention improve the social support for the spinal cord injury patients.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.43-50
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• 2021

Background/Objectives: Shoulder function is an important aspect of health related quality of life (QOL). Neck dissection impairment index (NDII) is a simple shoulder-specific questionnaire. This study aimed to evaluate the association between QOL and NDII in patients who underwent neck dissection to validate the Korean version of NDII. Materials & Methods: This study enrolled 74 patients with head and neck cancer who underwent neck dissection from December 2013 to April 2014. Patients completed questionnaires on QOL including the European Organization of Research and Treatment of Cancer 30-item Core QOL questionnaire (EORTC QLQ-C30) and NDII which was translated into Korean. Validity was evaluated by calculating the Pearson correlation coefficient between NDII and EORTC QLQ-C30. Results: We compared preoperative, postoperative within a week, 1st and 3rd months NDII scores. The total NDII scores were 14.7, 47.4, 33.7 and 34.3 each. Clinical variables including gender, site of primary tumor, performing revision neck dissection, radiotherapy and flap reconstruction were not significantly associated with NDII. However NDII mean score of patients who underwent unilateral neck dissection over 3 levels is most increased after operation. During all periods NDII scores were significantly associated with functioning score. Although other scores are lower correlation than function scores, global health status scores and symptom scores are also correlation with NDII. Conclusion: NDII was valid instrument and can be used not only in the clinical practice to assess shoulder dysfunction but also in the simple instrument to evaluate global QOL in Korea patients with having neck dissection.

• Journal of Microbiology and Biotechnology
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• v.25 no.7
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• pp.1170-1176
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• 2015

Ginsenosides, the major active component of ginseng, are traditionally used to treat various diseases, including cancer, inflammation, and obesity. Among these, compound K (CK), an intestinal bacterial metabolite of the ginsenosides Rb₁, Rb₂, and Rc from Bacteroides JY-6, is reported to inhibit cancer cell growth by inducing cell-cycle arrest or cell death, including apoptosis and necrosis. However, the precise effect of CK on breast cancer cells remains unclear. MCF-7 cells were treated with CK ($0-70{\mu}M$) for 24 or 48 h. Cell proliferation and death were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometry assays, respectively. Changes in downstream signaling molecules involved in cell death, including glycogen synthase kinase $3\beta$ ($GSK3\beta$), $GSK3\beta$, $\beta$-catenin, and cyclin D1, were analyzed by western blot assay. To block $GSK3\beta$ signaling, MCF-7 cells were pretreated with $GSK3\beta$ inhibitors 1 h prior to CK treatment. Cell death and the expression of $\beta$-catenin and cyclin D1 were then examined. CK dose- and time-dependently inhibited MCF-7 cell proliferation. Interestingly, CK induced programmed necrosis, but not apoptosis, via the $GSK3\beta$ signaling pathway in MCF-7 cells. CK inhibited $GSK3\beta$ phosphorylation, thereby suppressing the expression of $\beta$-catenin and cyclin D1. Our results suggest that CK induces programmed necrosis in MCF-7 breast cancer cells via the $GSK3\beta$ signaling pathway.

• Journal of Families and Better Life
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• v.31 no.2
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• pp.93-108
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• 2013

This study aimed to analyze the functionality and healthiness of family rules through a relational analysis of the relationship between the rule frequency by sub-family system and the content properties shown in the 'family constitution', It also aimed to examine the relationship between the perception degree of healthy family elements and the family subsystem rules and prepare the project development plans. As a result, it was a found that there were many dysfunctional rules, and healthiness was not satisfied. Project development plans include specific project plans, delivery systems, an orientation for practitioners, the necessity of evaluation and feedback, family health diagnosis, association with other project areas, and small scale operations.

• Korea Journal of Hospital Management
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• v.26 no.4
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• pp.1-11
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• 2021

This study is to identify the relationship among work-life balance and turnover intention of nurses and examine the influence of work-family balance, work-leisure balance, work-grow balance on turnover intention of nurses. Data were collected from nurses working at five hospitals with more than 30 beds in Seoul and analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation analysis and multiple regression analysis using Jamovi(1.6.23) program. The final sample were made up of 247 participants. In the correlation analysis, work-life balance and turnover intention showed negative correlation. As a result of multiple regression analysis, work-grow balance affected as a meaningful influence factor on turnover intention. It is necessary to carefully examine the sub-factors of work-life balance in order to understand the impact on turnover intention of nurses. And, hospitals need to provide organizational support for nurses' growth and career development.

• Korean Journal of Veterinary Research
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• v.51 no.2
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• pp.159-164
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• 2011

Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. Korean red ginseng (KRG) has been traditionally used for the treatment of liver disease. This study was conducted to evaluate the hepatoprotective effects of KRG against hepatotoxicity in Sprague- Dawley rats treated with ethanol (EtOH). Administration of EtOH for 20 days induced significant changes in serum biochemical parameters (aspartate aminotransferase, alanine transaminase, and glucose) accompanied by histological changes in the liver tissue. Treatment with KRG prior to administration of EtOH inhibited the EtOH-induced biochemical and histological changes of the liver. In perfused rat livers, administration of EtOH caused an increase in lactate dehydrogenase (LDH) release into the perfusate and activated the pro-apoptotic Bax protein but inhibited the anti-apoptotic Bcl-2 protein. Pretreatment with KRG prior to administration of EtOH decreased the EtOH-induced LDH release and inhibition of Bcl-2 protein. These results suggest that KRG exerts anti-apoptotic effects and alleviated EtOH-induced liver injury in rats.