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Prognostic Factors of Ovarian Response to Clomiphene Citrate in Patients with Polycystic Ovarian Syndrome (다낭성난소증후군 환자들에서 Clomiphene Citrate에 대한 난소 반응의 예측 인자들에 관한 연구)

  • Kim, Dae-Jin;Chae, Hee-Dong;Sohn, Cherl;Kim, Chung-Hoon;Kang, Byung-Moon;Chang, Yoon-Seok;Mok, Jung-Eun
    • Clinical and Experimental Reproductive Medicine
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    • v.25 no.2
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    • pp.141-151
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    • 1998
  • Objectives: To determine whether the body weight, body mass index (BMI), and basal serum level of LH, FSH, testosterone (T), dehydroepiandrosterone sulfate (DHEA-S) are related to the ovarian response to clomiphene citrate (CC) in patients with polycystic ovarian syndrome (PCOS). Materials and Method: From January 1996 to June 1997, total 57 patients with PCOS were enrolled in the present study. Women who had other infertility factors were excluded from our study. The ovulation induction using CC was used in all patients. The patients were grouped into 50 mg group, 100 mg group, and 150 mg group according to their daily CC dose. The patients were also grouped to ovulatory and non-ovulatory group. The body weight, BMI, and basal serum level of LH, FSH, T, DHEA-S were measured in all patients on the 2nd or 3rd day of the menstrual cycle. Results were analysed with Student's t-test and Fisher's exact test. Results: The body weight and BMI of the nonovulating group were significantly higher than those of the ovulating group in all groups (50, 100, 150 mg of CC). However, there were no significant differences of the level of LH and FSH between ovulating and nonovulating groups in all CC groups (50, 100, 150 mg). The level of T of nonovulating group was significantly higher in 50 and 100 mg of CC groups, but not in 150 mg group. The level of DHEA-S of the non-ovulating group is significantly higher in 50 mg group, but not in 100 and 150 mg groups. Conclusion: The body weight and BMI could be useful predictors of ovarian response to CC in patients with PCOS, and basal T and DHEA-S also might be useful in cases of low-dose CC treatment.

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A Critical Study on Validity of the Present Purpose of the Public Library Defined in the Korean Library Act ('도서관법(圖書館法)' 중(中) '공공도서관(公共圖書館)의 목적(目的)'에 대한 비판적(批判的) 고찰(考察))

  • Choi, Sung-Jin
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.2 no.1
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    • pp.132-177
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    • 1974
  • Toe public library may perform a social good only when its objectives are adequate to the community's needs. The present purpose of the public library in the Korean Library Act has no direct concern for our social needs from its very beginning because it was not created in response to our social needs but transplanted from American principles. It is, therefore. difficult to expect socially useful output of our public library programs under the present purpose which may be inadequate to our social tradition and needs. This study purposes to examine validity of the present purpose of the public library in the Korean Library Act, in the light of our community needs and our own library tradition. The methods employed to achieve the purpose of the study are (1) to survey needs of the library frequenters through questionnaire, and interviews with the public librarians in Seoul, (2) to gather the statistical data relevant to, and supporting, the hypothesis, and (3) to compare our social background with that of the United States of which the American purpose, a model for our present purpose, came out. The conclusion is as follows: A. The idea to induce people to pull themselves upward by providing for all the members of the community access to the world's best books shelved in the public library should be abandoned. The reasons are (1) that the idea is alien in our public library tradition, (2) that little demand of the community goes with the idea, and (3) that reading outside the library has come into wide practice, thanks to recent increase in individual income and that in publications. B. That the public library maintains fiction and other recreational reading materials is meaningless in the light of the community needs. These are the two explanations supporting the thesis. (1) The "uplift" theory has proved inoperative and people apparently do not progress from, light fiction to more respectable fare. (2) The conviction that fiction and other recreational reading materials keep the middling classes from the "vicious" entertainments maintaining order in the community by giving them a harmless source of recreation has lost its significance as the modern society provides a number of choices in recreation: television is an obvious example. C. The nature of the informational needs of the community has radically changed, so radically as to require substantial changes in the outlook, collections, and services of the public library, which is :slow in adopting itself to the new social surroundings in Korea. D. 92.2 per Cent of the present frequenters of the public library are high school and college students. Since the library is to meet the existing community needs it should turn its attention to the student group, and develop the means to serve it better, not the "theoretical group of specialists who do not come to "the public library. E. In revision of the purpose of the public library, priority of each objective should be given. The priorities in the last analysis are research and information. culture, recreation in that order.

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The Perception of Middle School Science-Gifted Students on the 'Science Writing Heuristic' Class Emphasizing Social Interaction and Tool Improvement (사회적 상호작용과 도구 개선을 강조한 '탐구적 과학 글쓰기' 수업에 대한 중학교 과학 영재 학생들의 인식)

  • Shin, Eunji;Choi, Wonho
    • Journal of The Korean Association For Science Education
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    • v.41 no.1
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    • pp.1-10
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    • 2021
  • In this study, a science writing heuristic class with emphasis on social interaction and tool improvement for 10 middle school students at the National University Science-Gifted Education Center in Jeollanamdo was conducted to investigate the perception of STS (science technology society) relationship and students' perception of the effects of class. After science writing heuristic class emphasizing social interaction and tool improvement, the students became aware of the STS relationships as follows: Science-gifted students have come to perceive that experimental tools and technology contribute to the development of scientific theory, that it is difficult to solve all social problems with only science and technology, and that science is a social interaction activity. In addition, science-gifted students responded that they became aware of the relevance of STS through intensive inquiry conducted on the same subject for several hours, communications with colleagues in another group through peer reviews, communication to solve problems with colleagues in the same group, activities to improve tools in the process of inquiry, inquiry using familiar materials and phenomena. In order for students to effectively recognize the relationship of STS in science-gifted class for middle school students, it is necessary to provide experience to solve problems using various experimental tools, experience to have trial and error in the process of solving inquiry problem under the same subject, experience to improve tools in the process of solving inquiry problem, experience to communicate with colleagues who conduct inquiry activities under the same subject, experience to share the results with other groups, and inquiry activities using familiar materials and phenomena.

A Study on form of 'collar' in the China and Mongolian Traditional OverCoat & National Costume -Focusing on 13th Century's- (중국 및 몽고제국의 포제와 민족복에 나타난 ' 깃 (옷깃)'에 대한 연구 -13세기를 중심으로-)

  • 김은주
    • Journal of the Korean Society of Costume
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    • v.19
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    • pp.209-240
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    • 1992
  • The costume of any nation is an attribute of a culture. This study concerns chinese and Mongolian costume's 'collar' form according to the observation of some reports about import folk materials and the pictures of the genuine objects, the author has investigated and rearranged them focusing on 13th Century's. 1. Traditional OverCoat or National costume on the poing of won dynasty in china such as Jacket, Coat, Mantle for making classical matching color, lacing, pearl pieces, and all costume shall be properly decorated and disigned. The example, Chinese Women's Gown and Double Jacket, on top of alignment of plaid, focus shall be placed on chinese classical form and color-matching, such as flowers and bireds, butterflies, made wishing ornaments, which shall be either hand painted or embroidered on collars, fronts, sleeves openings, and lower portion of gown. 2. Mongolian Costume, the stone status of a person, are seen at the territory of the Republic of Mongolia was a powerful country of Asia. So during the Mongolian Empire a lot of Missions from many countries came to kharakorom for establishing official relations between Mongolia and a country represented by mission. In particularly, the costume of mongols on the point of Chinggis khan Empire which the upper clothes in cluded ; a several kinds of the Caftan as compared with in Korea as to material (Silk caftan, Cotton Caftan, Fur Caftan) with closing to the right due to overlapping and Stand-up-Shawl Collars will pancho style & Round or V Neckline. 3. As compared with in Korea it is said that this a sort of Simui was brought in prior to the middle of Koryeo dynasty. Korean Simui system was complied with chinese system through confucian domestic behaviour. This was respected for court dress of confucian scholars, as it was, Chumri can ordinary dress of schloars) and Hakchangui ( a uniform of confucian student). Generally its form or shape of the outer lapels of Korean jacket were used together Squar-Tray-Collar. In late Yi-dynasty the inside collar length was longer than the outside collar length and the width of the collar was gradually narrow. And so the Traditional costume's outer collar of Jacket and OverCoat became small while the width and length of breast-tie became large. The same thing as the form of the collar on these days had been appeared by the design method or adjust one's dress. Therefore the form of collar in the china and Mongolian Traditional OverCoat & National Costume is fix arranged according to Stand up Collar, Without Collar, Clothing to the Right, Central opening, Horizontal Row of Button with Round or V Neckline and so on.

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Cognition of Middle School Students about 'The Material and Change of the Earth's Crust' ('지각의 물질과 변화' 단원에 대한 중학생들의 인식)

  • Hwang, Ji-Hyeon;Kim, Cheong-Bin;Cho, Kyu-Seong
    • Journal of the Korean earth science society
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    • v.24 no.3
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    • pp.128-134
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    • 2003
  • This study is focused on how much middle school students who study the chapter of first-grade science,'The Material and Change of the Earth's Crust', connect and understand what they learn with their environment and surroundings. This paper will discuss the connection between school education and living surroundings and how much the difference between the surroundings influences students' concepts and attitudes toward science. This study included 330students in the second year of middle schools from Jeonju, Buan and Jinan in Jeollabuk-do. This study analyzed students' concepts of mineral and rocks by having them observe samples in class. Only 16 percent of the students observe surrounding rocks with interest, but most of them are not interested. Chaesukgang and Mountain Mai are two local places in Jeollabuk-do which have a lot of specific stratum and geological structures, so it's easy for teachers to provide an outdoor experience by showing the students rocks and geological structures. Although which students have a little more observation experience than Jeonju area students, students who throughout the county seldom do outdoor observation learning. By collecting and observing the surrounding minerals and rocks, along with teaching the chapter 'The Materials and Change of the Earth's Crust', and by visiting outdoor locations while teaching about geological structures, we can improve our teaching.

Cyclic fatigue resistance of M-Pro and RaCe Ni-Ti rotary endodontic instruments in artificial curved canals: a comparative in vitro study

  • Feky, Hadeer Mostafa El;Ezzat, Khalid Mohammed;Bedier, Marwa Mahmoud Ali
    • Restorative Dentistry and Endodontics
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    • v.44 no.4
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    • pp.44.1-44.11
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    • 2019
  • Objectives: To compare the flexural cyclic fatigue resistance and the length of the fractured segments (FLs) of recently introduced M-Pro rotary files with that of RaCe rotary files in curved canals and to evaluate the fracture surface by scanning electron microscopy (SEM). Materials and Methods: Thirty-six endodontic files with the same tip size and taper (size 25, 0.06 taper) were used. The samples were classified into 2 groups (n = 18): the M-Pro group (M-Pro IMD) and the RaCe group (FKG). A custom-made simulated canal model was fabricated to evaluate the total number of cycles to failure and the FL. SEM was used to examine the fracture surfaces of the fragmented segments. The data were statistically analyzed and comparisons between the 2 groups for normally distributed numerical variables were carried out using the independent Student's t-test. A p value less than 0.05 was considered to indicate statistical significance. Results: The M-Pro group showed significantly higher resistance to flexural cyclic fatigue than the RaCe group (p < 0.05), but there was no significant difference in the FLs between the 2 groups (p ≥ 0.05). Conclusions: Thermal treatment of nickel-titanium instruments can improve the flexural cyclic fatigue resistance of rotary endodontic files, and the M-Pro rotary system seems to be a promising rotary endodontic file.

Hesa-A Down-Regulates erb/b2 Oncogene Expression and Improves Outcome of Oral Carcinoma in a Rat Model

  • Abbasi, Mehran Mesgari;Mehdipour, Masoumeh;Monfaredan, Amir;Jahanban-Esfahlan, Rana
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.6947-6951
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    • 2015
  • Background: Oral carcinoma (OC) remains one of the most difficult malignancies to cure. Hesa-A is an Iranian herbal-marine compound that has shown promising anti-tumor properties against various human tumors. However, its mechanism of action remains to be addressed. The present study was conducted to evaluate the effect of two doses of Hesa-A on mRNA expression of erb$\backslash$b2 as a main prognosticator tumor marker for OC in an animal model. Materials and Methods: A total of 60 rats were randomly divided into 5 groups of 12 animals each. Rats in carcinoma groups received 0, 250 and 500mg/kg body weight doses of Hesa-A 3 times a day. The other two groups were considered as treated and untreated control groups. At the end of the experiment, animals were sacrificed and tongue tissues subjected to H and E staining and real time PCR. Results: Our results showed that compared to the control group, erb$\backslash$b2 was over-expressed ~ 30% in the carcinoma group. After treatment with 250mg/kg and 500mg/kg body weight of Hesa-A, erb$\backslash$b2 levels dropped by 24.1% and 3.4 % respectively compared to the control carcinoma group (p<0.01, p<0.0001). Moreover, there was a significant relation between erb$\backslash$b2 mRNA content and observed pathological changes in studied groups (p<0.05). Conclusions: These data provide insight into mechanism(s) by which Hesa-A may improve clinical outcome of oral carcinoma by affecting oncogene erb$\backslash$b2 expression and suggest Hesa-A as an effective chemotherapeutic agent in treatment of HER+tumors.

A Study on Risk Communication and Risk Perception in Environmental Problems (환경문제의 위해도 인식과 위해도 홍보 프로그램의 효과분석 -라돈과 다이옥신을 중심으로-)

  • 김진용;신동천;박성은;임영욱;황만식
    • Environmental Analysis Health and Toxicology
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    • v.17 no.4
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    • pp.315-324
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    • 2002
  • Risk communication can be defined as the exchange of information about the nature, magnitude, significance, acceptability, and management of risk. The effect of risk communication on the perception and knowledge towards risk of environmental pollutants and it's related factors were investigated in this study. To investigate perception and knowledge of students and teachers towards risk of environmental pollutants, we conducted the survey using self-administrated questionnaire. The subjects were 574 for the first survey and 465 for the seconds survey from May to June, 2000. The main methods of transmission used in this study- through video tape, visual materials, question and answer, and participation in measuring pollutants - were not a one - way street. But an interactive process where information and opinions were exchanged among individuals, groups, and institutions. Environmental pollutants measured with participation of study subjects was Radon in the class room. The concentration of Radon was measured using E -PERM Device by installing it at each site for about 5 days. Subjects showed much interest in environmental pollution. Also, more than 98% of total subjects were perceived as Korea is seriously contaminated at present. By risk communication activity, risk perception of all subjects about Radon was increased, on the other hand, risk perception of Dioxin was decreased except for elementary student. Moreover, knowledge of all subjects about environmental risk was significantly increased (p =0.0001) and effort of reducing environmental pollution was more increased (p<0.05). There is need to further develop, refine, and integrate these approaches environmental risk communication study, there is an even more pressing need to accelerate the diffusion of environmental risk communication practice into government and organizations.

CLINICAL STUDY ON KOREAN POSTERIOR MAXILLAE RELATED TO DENTAL IMPLANT TREATMENT (치과임플란트 치료와 관련된 상악구치부의 임상적 연구)

  • Lee, Du-Han;Lee, Seong-Hyun;Hwang, Ju-Hong;Lee, Jeong-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.32 no.1
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    • pp.27-31
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    • 2010
  • Purpose of study: The purpose of this study was to provide adequate diagnostic guideline for the maxillary sinuses prior to dental implant treatment for edentulous posterior maxillary areas. For this purpose, our procedure involves the estimation of the remaining alveolar bone height, the examination of the anatomical variation in the maxillary sinuses (e.g. sinus septum), and the evaluation of the incidence of preoperative pathological conditions in the maxillary sinuses. Materials and Methods: We selected 189 patients to undergo computerized tomography (CT) in order to account for the posterior maxillary anatomy found in patients of Korean ethnicity. We evaluated the following using Dentascan software: Remaining alveolar bone height, incidence of sinus septum, and rate of preoperative pathologic conditions in the maxillary sinus. The average amount of remaining alveolar bone height was analyzed using the student's t-test for differences according to anatomical site, and the ANOVA was used for the differences according to age group with the level of significance set at 0.05. Results: Alveolar bone heights of upper first premolar, second premolar, first molar, and second molar was 12.24 mm, 10.37 mm, 7.16 mm, and 7.15 mm, respectively with statistical significance (P < 0.05). Incidence of sinus septum as an anatomic variation was 17 out of 189 cases (9.0%). Incidence of mucosal thickening as a pathologic variation was 82 out of 189 cases (43.4%). Conclusion: In treatment planning of posterior maxillary edentulous area of Koreans, the consideration of augmentation surgery for maxillary sinus is required in maxillary molar area before dental implant installation, and preoperative screening of the asymptomatic maxillary sinuses can be regarded as a reasonable preoperative procedure in the planning of dental implant treatment on the posterior maxillary edentulous area.

A Study on the Effect of Collaborative Instruction Between a Teacher Librarian and a Korean Language Teacher on a Middle School Student's Learning Interest and Academic Achievement (사서교사와 국어교사의 협동수업이 중학생의 학습흥미와 학업성취도에 미치는 영향에 대한 연구)

  • Ki, Min-Jin;Song, Gi-Ho
    • Journal of the Korean Society for Library and Information Science
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    • v.47 no.2
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    • pp.123-142
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    • 2013
  • The aim of this study is to find out the impact of collaborative instruction between the teacher librarian and the classroom teacher on learning interest and academic achievement by running Library and Information Life, which is the textbook of information literacy for teacher librarians and the Korean language curriculum for the first grade of middle school through library-based instruction. The result of this study has a positive influence on academic achievement by facilitating learning interest on Korean language classes under coplanning, co-operating and coevaluating in the school library. Therefore, it is important to establish the institutional system for collaborative instruction in order to increase information literacy instruction in the school community. A local school should expand the physical environment and educational equipment of its school library and form a flexible schedule to have enough time for teaching information literacy skills and for using of materials.