• 제목/요약/키워드: structure modeling

검색결과 3,672건 처리시간 0.038초

3D Structure of Bacillus halodurans O-Methyltransferase, a Novel Bacterial O-Methyltransferase by Comparative Homology Modeling

  • Lee, Jee-Young;Lee, Sung-Ah;Kim, Yang-Mee
    • Bulletin of the Korean Chemical Society
    • /
    • 제28권6호
    • /
    • pp.941-946
    • /
    • 2007
  • Bacillus halodurans O-methyltransferase (BhOMT) is a S-adenosylmethionine (SAM or AdoMet) dependent methyltransferase. Three dimensional structure of the BhOMT bound to S-adenosyl-L-homocysteine (SAH or AdoHcy) has been determined by comparative homology modeling. BhOMT has 40% sequence identity with caffeoyl-CoA 3-O-methyltransferase (CCoAOMT) from alfalfa. Based on x-ray structure of CCoAOMT, three dimensional structure of BhOMT was determined using MODELLER. The substrate binding sites of these two proteins showed slight differences, but these differences were important to characterize the substrate of BhOMT. Automated docking study showed that four flavonoids, quercetin, fisetin, myricetin, and luteolin which have two hydroxyl groups simultaneously at 3'- and 4'-position in the B-ring and structural rigidity of Cring resulting from the double bond characters between C2 and C3, were well docked as ligands of BhOMT. These flavonoids form stable hydrogen bondings with K211, R170, and hydroxyl group at 3'-position in the Bring has stable electrostatic interaction with Ca2+ ion in BhOMT. This study will be helpful to understand the biochemical function of BhOMT as an O-methyltransferase for flavonoids.

Determinant Factors of Firm Risk - Using the Structural Equation Modeling Approach: Evidence from Indonesia

  • WULANDARI, Asih Marini;RAHAYU, Sri Mangesti;SAIFI, Muhammad;NUZULA, Nila Firdausi
    • The Journal of Asian Finance, Economics and Business
    • /
    • 제9권8호
    • /
    • pp.47-55
    • /
    • 2022
  • The purpose of this study was to determine the relationship between company risk and factors such as business size, ownership structure, and leverage. The study was conducted on 142 manufacturing sector companies listed on the Indonesia Stock Exchange from 2013 to 2018. The purposive sampling method was used to select the research sample. The sample size for this study was 21 different companies. The analytical approach uses Structural Equation Modeling (SEM) with WarpPLS. According to the findings of the investigation, the size of the company has a significant influence on both the amount of leverage the company uses and the amount of risk the company takes. The level of leverage is significantly influenced by the ownership structure. However, the ownership structure does not have a significant impact on the level of risk the company; rather, leverage has a big impact on the level of risk the company faces. The findings of this study are helpful to prospective investors in measuring the risk posed by the company to make judgments regarding investments. The findings of this study are also essential for management to consider while controlling the risk of the organization.

MFC 작동기를 이용한 수중 Hull 구조물의 능동 진동 제어 (Active Vibration Control of Smart Hull Structure in Underwater Using Micro-Fiber Composite Actuators)

  • 권오철;손정우;최승복
    • 한국소음진동공학회:학술대회논문집
    • /
    • 한국소음진동공학회 2008년도 추계학술대회논문집
    • /
    • pp.466-471
    • /
    • 2008
  • Structural vibration and noise are hot issues in underwater vehicles such as submarines for their survivability. Therefore, active vibration and noise control of submarine, which can be modeled as hull structure, have been conducted by the use of piezoelectric materials. Traditional piezoelectric materials are too brittle and not suitable to curved geometry such as hull structures. Therefore, advanced anisotropic piezoceramic actuator named as Macro-Fiber Composite (MFC), which can provide great flexibility, large induced strain and directional actuating force is adopted for this research. In this study, dynamic model of the smart hull structure is established and active vibration control performance of the smart hull structure is evaluated using optimally placed MFC. Actuating performance of MFC is evaluated by finite element analysis and dynamic modeling of the smart hull structure is derived by finite element method considering underwater condition. In order to suppress the vibration of hull structure, Linear-Quadratic-Gaussian (LQG) algorithm is adopted. After then active vibration control performance of the proposed smart hull structure is evaluated with computer simulation and experimental investigation in underwater. Structural vibration of the hull structure is decreased effectively by applying proper control voltages to the MFC actuators.

  • PDF

MFC 작동기를 이용한 수중 Hull 구조물의 능동 진동 제어 (Active Vibration Control of Underwater Hull Structure Using Macro-Fiber Composite Actuators)

  • 권오철;손정우;최승복
    • 한국소음진동공학회논문집
    • /
    • 제19권2호
    • /
    • pp.138-145
    • /
    • 2009
  • Structural vibration and noise are hot issues in underwater vehicles such as submarines for their survivability. Therefore, active vibration and noise control of submarine, which can be modeled as hull structure, have been conducted by the use of piezoelectric materials. Traditional piezoelectric materials are too brittle and not suitable to curved geometry such as hull structures. Therefore, advanced anisotropic piezocomposite actuator named as Macro-Fiber Composite(MFC), which can provide great flexibility, large induced strain and directional actuating force is adopted for this research. In this study, dynamic model of the smart hull structure is established and active vibration control performance of the smart hull structure is evaluated using optimally placed MFC. Actuating performance of MFC is evaluated by finite element analysis and dynamic modeling of the smart hull structure is derived by finite element method considering underwater condition. In order to suppress the vibration of hull structure, Linear Quadratic Gaussian(LQG) algorithm is adopted. After then active vibration control performance of the proposed smart hull structure is evaluated with computer simulation and experimental investigation in underwater. Structural vibration of the hull structure is decreased effectively by applying proper control voltages to the MFC actuators.

2차 볼테라 모델을 이용한 Super-RENS 시스템의 비선형 모델링 (Nonlinear Modeling of Super-RENS System Using a Second-Order Volterra Model)

  • 서만중;심희성;임성빈
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2008년도 하계종합학술대회
    • /
    • pp.975-976
    • /
    • 2008
  • Reliable channel modeling becomes an important measure in performance evaluation on various data detection algorithms. For this reason, correct and accurate modeling is required. This paper presents a nonlinear modeling of Super-RENS (Super-Resolution Near Field Structure) read-out signal using the second-order Volterra model.

  • PDF

후막 전계발광소자의 전기적 등가 모델링 (Electrical Equivalent modeling of Powder Electroluminescent Device)

  • 이종찬;박대희
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 1998년도 추계학술대회 논문집
    • /
    • pp.49-52
    • /
    • 1998
  • In this paper, to implement the electrical equivalent modeling of powder electroluminescent device, capacitate equation of device was chosen. The conventional structure device which have dielectric and phosphor layer between electrodes, and the single emission structure device which means that dielectric and phosphor were mixed between electrodes, were investigated. As a result, it was possible to make the equation that is transferred capacitance to phosphor layer, and using measured brightness efficiency and conductivity of devices was calculated.

  • PDF

Design of improved Mulit-FNN for Nonlinear Process modeling

  • Park, Hosung;Sungkwun Oh
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 제어로봇시스템학회 2002년도 ICCAS
    • /
    • pp.102.2-102
    • /
    • 2002
  • In this paper, the improved Multi-FNN (Fuzzy-Neural Networks) model is identified and optimized using HCM (Hard C-Means) clustering method and optimization algorithms. The proposed Multi-FNN is based on FNN and use simplified and linear inference as fuzzy inference method and error back propagation algorithm as learning rules. We use a HCM clustering and genetic algorithms (GAs) to identify both the structure and the parameters of a Multi-FNN model. Here, HCM clustering method, which is carried out for the process data preprocessing of system modeling, is utilized to determine the structure of Multi-FNN according to the divisions of input-output space using I/O process data. Also, the parame...

  • PDF

유압식 반능동 진동 흡수기의 모델링과 제어 (Modeling and Control of a Hydraulic Semiactive Vibration Absorber)

  • 모창기
    • 소음진동
    • /
    • 제8권4호
    • /
    • pp.700-705
    • /
    • 1998
  • Recent past work has demonstrated that hydraulic semiactive vibration absorbers hold the promise of providing an ideal means of mitigating structural vibration. This paper examines a factor that must be treated when designing a hydraulic semiactive vibration absorber for application to a full scale structure; fluid compressibility. An expanded and consistent dynamic model of the flow process is first established. A simple feedback control is then tested on a single degree of freedom laboratory structure to verify the findings.

  • PDF

Rule-Based Fuzzy Polynomial Neural Networks in Modeling Software Process Data

  • Park, Byoung-Jun;Lee, Dong-Yoon;Oh, Sung-Kwun
    • International Journal of Control, Automation, and Systems
    • /
    • 제1권3호
    • /
    • pp.321-331
    • /
    • 2003
  • Experimental software datasets describing software projects in terms of their complexity and development time have been the subject of intensive modeling. A number of various modeling methodologies and modeling designs have been proposed including such approaches as neural networks, fuzzy, and fuzzy neural network models. In this study, we introduce the concept of the Rule-based fuzzy polynomial neural networks (RFPNN) as a hybrid modeling architecture and discuss its comprehensive design methodology. The development of the RFPNN dwells on the technologies of Computational Intelligence (CI), namely fuzzy sets, neural networks, and genetic algorithms. The architecture of the RFPNN results from a synergistic usage of RFNN and PNN. RFNN contribute to the formation of the premise part of the rule-based structure of the RFPNN. The consequence part of the RFPNN is designed using PNN. We discuss two kinds of RFPNN architectures and propose a comprehensive learning algorithm. In particular, it is shown that this network exhibits a dynamic structure. The experimental results include well-known software data such as the NASA dataset concerning software cost estimation and the one describing software modules of the Medical Imaging System (MIS).

The effect of finite element modeling assumptions on collapse capacity of an RC frame building

  • Ghaemian, Saeed;Muderrisoglu, Ziya;Yazgan, Ufuk
    • Earthquakes and Structures
    • /
    • 제18권5호
    • /
    • pp.555-565
    • /
    • 2020
  • The main objective of seismic codes is to prevent structural collapse and ensure life safety. Collapse probability of a structure is usually assessed by making a series of analytical model assumptions. This paper investigates the effect of finite element modeling (FEM) assumptions on the estimated collapse capacity of a reinforced concrete (RC) frame building and points out the modeling limitations. Widely used element formulations and hysteresis models are considered in the analysis. A full-scale, three-story RC frame building was utilized as the experimental model. Alternative finite element models are established by adopting a range of different modeling strategies. Using each model, the collapse capacity of the structure is evaluated via Incremental Dynamic Analysis (IDA). Results indicate that the analytically estimated collapse capacities are significantly sensitive to the utilized modeling approaches. Furthermore, results also show that models that represent stiffness degradation lead to a better correlation between the actual and analytical responses. Results of this study are expected to be useful for in developing proper models for assessing the collapse probability of RC frame structures.