• IMMUNE NETWORK
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• v.13 no.5
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• pp.168-176
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• 2013

In the last few years major progress has been made in better understanding the role of natural killer (NK) cells in hepatitis C virus (HCV) infection. This includes multiple pathways by which HCV impairs or limits NK cells activation. Based on current genetic and functional data, a picture is emerging where only a rapid and strong NK cell response early on during infection which results in strong T cell responses and possible subsequent clearance, whereas chronic HCV infection is associated with dysfunctional or biased NK cells phenotypes. The hallmark of this NK cell dysfunction is persistent activation promoting ongoing hepatitis and hepatocyte damage, while being unable to clear HCV due to impaired IFN-${\gamma}$ responses. Furthermore, some data suggests certain chronically activated subsets that are $NKp46^{high}$ may be particularly active against hepatic stellate cells, a key player in hepatic fibrogenesis. Finally, the role of NK cells during HCV therapy, HCV recurrence after liver transplant and hepatocellular carcinoma are discussed.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.11
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• pp.1288-1296
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• 2011

Effective elastic constants of bone-like biocomposites are investigated numerically. The bone-like materials are composed of strong layers and weak layers, and hierarchically structured. The unit cell model is employed to obtain the effective elastic constants. The effective anisotropic elastic constants of bone-like composites are obtained by using the potential energy method and finite element analysis. The effects of the Poisson's ratio, elastic modulus, hierarchical level, volume fraction and aspect ratio of the strong layer composed of the composites on the effective elastic constants are discussed.

• Proceeding of EDISON Challenge
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• 2015.03a
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• pp.428-441
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• 2015

Corresponding to the high consumption rate of the selfie stick for cell phone camera, the design of the product is becoming diverse. However, relatively low cost selfie stick models are not strong enough to stand the weight of the cell phone. This results into a bending of the stick or the accidental fall of the cell phone by the failure of the holding unit. As a solution to the problem, design of selfie stick that is structurally strong enough to stand the weight of the cell phone with the minimum weight for the portability is proposed in this paper.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.1568-1569
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• 2007

TFT-LCD used in display area is not a light-emissive device itself but TFT-LCD can overcome through the employ of the backlight unit (BLU). BLU is very important device in TFT-LCD system. However, the old-fashion BLU of CCFL type is crucible to the health due to the contained material, mercury (Hg). Moreover, strong temperature dependency of lamp employed with Hg becomes the other disadvantage in practical usage. To solve these problems, Hg-Free lamp with strong thermal resistance property is required to displace the Hg lamp. We studied optical and electrical properties of Xe-Ne-He mixed gas that is dependent on change of mixed ratio and pressure. In our results, the designed lamp without the phosphorescent material has the lowest firing voltage at xe 50%(Ne:He=9:1).

• East Asian Economic Review
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• v.23 no.2
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• pp.149-168
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• 2019

Public information arrivals and their immediate incorporation in asset price is a key component of semi-strong form of the Efficient Market Hypothesis. In this study, we explore the impact of public information arrivals on cryptocurrency market via Twitter posts. The empirical analysis was conducted through various methods including Kapetanios unit root test, Maki cointegration analysis and Markov regime switching regression analysis. Results indicate that while in bull market positive public information arrivals have a positive influence on Ripple's value; in bear market, however, even if the company releases good news, it does not divert out the Ripple from downward trend.

• The Bulletin of The Korean Astronomical Society
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• v.45 no.1
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• pp.61.3-61.3
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• 2020

We present spatially resolved outflows and photoionization for a pilot sample of 11 type 1 AGNs (z<0.3) based on the Gemini Multi-Object Spectrograph Integral Field Unit data. These AGNs were selected since we found strong outflow signatures in SDSS spectra. We focus on [OIII] and Hα emission lines to probe outflow kinematics by measuring line flux, velocity, and velocity dispersion at each pixel. We investigate characteristics of gas kinematics of type 1 AGNs and compare them with those of type 2 AGNs in our previous studies. Furthermore, by drawing BPT map, photoionization states will be also discussed. Based on the results, we discuss various implications on the impacts of outflows on star formation in host galaxies.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.47 no.4
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• pp.338-343
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• 2011

To obtain the effective sampling estuarine fauna by a passive net in the West Sea of Korea occurring strong tide, catch were collected by bag nets with various sampling trials off Ganghwa Island in November 2009. We compared the difference of community structures (on spring tide vs. neap tide, total sample vs. subsample and 4 nets vs. 1 net) with each species composition as a sampling unit by the Pearson chi-square test. Number of individual at the spring tide was more abundant than that at the neap tide (p<0.0001) although number of species at the spring tide was not significantly different with that at the neap tide (p=0.174). Both number of species (p=0.138) and number of individual (p=0.096) were not significantly different between total sample and random subsample. Number of species was not significantly different between the subsample by 1 net and the subsample by 4 nets (p=0.515), but number of individual was a little different on both samples (p=0.024). In conclusion, we suggest the subsample by 1 net at spring tide as the effective sampling estuarine fauna by a passive net in the West Sea occurring strong tide.

• Journal of the Korean Ceramic Society
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• v.52 no.1
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• pp.66-71
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• 2015

$NaY_{1-x}(WO_4)_2:Ho^{3+}/Yb^{3+}$ phosphors with doping concentrations of $Ho^{3+}$ and $Yb^{3+}$ ($x=Ho^{3+}+Yb^{3+}$, $Ho^{3+}=0.05$, 0.1, 0.2, and $Yb^{3+}=0.2$, 0.45) were successfully synthesized via the cyclic microwave-modified sol-gel route; their upconversion properties were investigated. Well-crystallized particles showed a fine and homogeneous morphology with particle sizes of $2-5{\mu}m$. Under excitation at 980 nm, the synthesized particles exhibited yellow emissions based on a strong 550-nm emission band in the green region and a very strong 655-nm emission band in the red region. The Raman spectra of the doped particles indicated the domination of strong peaks at higher and lower frequencies induced by the incorporation of the $Ho^{3+}$ and $Yb^{3+}$ elements into the $Y^{3+}$ sites in the crystal lattice, which resulted in unit cell shrinkage that accompanied a new phase formation of the $WO_{4-x}$ group.

• Journal of the Korean Society for Nondestructive Testing
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• v.27 no.6
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• pp.556-562
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• 2007

This paper presents the use of a novel fiber optic accelerometer system to monitor ambient vibration (both wind-induced one and vehicle-induced) of a real bridge structure. This sensor system integrates the $Moir\'{e}$ fringe phenomenon with fiber optics to achieve accurate and reliable measurements. A low-cost signal processing unit implements unique algorithms to further enhance the resolution and increase the dynamic bandwidth of the sensors. The fiber optic accelerometer has two major benefits in using this fiber optic accelerometer system for monitoring civil engineering structures. One is its immunity to electromagnetic (EM) interference making it suitable for difficult applications in such environments involving strong EM fields, electrical spark-induced explosion risks, and cabling problems, prohibiting the use of conventional electromagnetic accelerometers. The other is its ability to measure both low- and high-amplitude vibrations with a constantly high resolution without pre-setting a gain level, as usually required in a conventional accelerometer. The second benefit makes the sensor system particularly useful for real-time measurement of both ambient vibration (that is often used for structural health monitoring) and strong motion such as earthquake. Especially, the semi-strong motion and the small ambient one are successfully simulated and measured by using the new fiber optic accelerometer in the experiment of the structural health monitoring of a real bridge.

• BMB Reports
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• v.38 no.2
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• pp.161-166
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• 2005

Functional protein of MB78 bacteriophage having apparent molecular weight of 22 kDa is expressed from 1.7 kb HindIII G fragment. The nucleotide sequence of this fragment showed two open reading frames of 222 and 196 codons in tail-to-tail orientation separated by a 62-nucleotide intercistronic region. The ORF of 22 kDa protein is present in opposite orientation, i.e. in the complementary strand, preceded by a strong ribosomal binding site and a promoter sequence. Another ORF started from the beginning of the fragment whose promoter region and translational start site lies in the 0.45 kb HincII U fragment which is located next to the HindIII G fragment, that has the sequence for DNA bending. 3' end of the fragment has high sequence homology to the EaA and EaI proteins of bacteriophage P22, a close relative of MB78 phage.