• Journal of Yeungnam Medical Science
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• 제23권1호
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• pp.131-137
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• 2006

Small bowel tumors have been difficult to diagnose because of low incidence and absence of specific symptoms. There are no efficient and accurate tests available for diagnosis. Capsule endoscopy is an efficient diagnostic tool for small bowel disease and obscure gastrointestinal bleeding. We diagnosed two cases of small bowel gastrointestinal stromal tumor (GIST) diagnosed by capsule endoscopy that were treated by surgery. A 68 year old male presented with abdominal pain. The capsule endoscopy showed fungating ulcer mass at the jejunum. A 55 year female presented with melena. The capsule endoscopy showed an intraluminal protruding mass with a superficial ulcer at the jejunum. Two cases were diagnosed with GIST after surgery. We report these two case diagnosed by capsule endoscopy and review the medical literature.

• Journal of Veterinary Science
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• 제24권2호
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• pp.30.1-30.6
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• 2023

A 4-year-old Chihuahua dog was referred for bilateral corneal ulcers. Slightly raised white fluorescein-positive plaque-like corneal lesions in both eyes appeared as intense hyperreflective areas with posterior shadowing on optical coherence tomography (OCT). Based on corneal cytology and culture, Candida albicans-induced fungal keratitis was diagnosed. Despite treatment, on OCT, endothelial plaques, increased stromal infiltration thickness, vertical shapes of the ulcer edge, and necrotic stromal space were judged to be aggravation of the disease, and surgery was performed. Conjunctival grafting surgery with topical 1% voriconazole effectively resolved fungal keratitis. OCT can provide detailed and objective information related to the disease prognosis.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2008년도 추계학술대회
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• pp.170-170
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• 2008

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2002년도 추계학술대회초록집
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• pp.66-79
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• 2002

The basic treatments - Epithelial ＆ stromal debridement with a swab or diamond burr. - Possible placement of a collagen shield or nictitans flap. - Topical treatment with Adequan IM diluted in artificial tears : 1 ml Adequan + 4 ml tears : One drop four times daily. - Topical treatment with an antibiotic drop : Three times daily - 5％ sodium chloride ointment : Four times daily. If inflammation is severe - Topical treatment with nonsteroidal agent : Four times daily (Voltaren, Ocufen, or Profenyl) - Cyclosporine A (Optimmune) : Twice daily Healing time - Healing typically occurs rapidly - Fluorescein negative : 7-10 days - Vascular keratitis : Often several months

• 한국임상수의학회지
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• 제28권6호
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• pp.562-565
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• 2011

2008년 1월부터 2010년 3월까지 만성 각막 상피 결손증으로 서울대학교 부속 동물병원에 내원한 환자 27마리 (25두: 단안, 2두: 양안)를 대상으로 점안마취 하에 격자 각막 절개법을 적용하였다. 처치 후 7-14일 간격으로 재진하였으며, 형광염색 시 음성이고, 각막 표면이 안정화될 때까지 반복 처치하였다. 이중 86.2%에 해당하는 25안에서 각막 궤양이 치유되었으며, 평균 치유기간은 $15.92{\pm}9.19$일 (7-39일)이었다. 병변이 악화되거나 각막 절개법을 최초로 시행 후 6주가 지나도 병변이 치유되지 않는 4안의 경우, 전신마취 하에 각막 절개법 및 제 3 안검 플랩을 적용하였으며, 2주 후 플랩을 제거했을 때, 병변이 모두 치유된 것을 확인하였다. 따라서, 각막 절개법은 만성 각막 상피 결손증에 유용한 치료법이라고 사료되며, 반복적인 처치에도 재발하거나 시술의 성공률을 높이기 위해서는 각막절개법과 제 3 안검 플랩을 함께 실시할 것이 추천된다.

• Journal of Yeungnam Medical Science
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• 제23권1호
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• pp.45-51
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• 2006

소장질환을 진단하는데 있어서 캡슐내시경의 유용성을 평가하고자 본 연구를 시행하였다. 2003년 8월부터 2006년 3월까지 영남대학병원에서 캡슐내시경을 시행한 66명(평균나이: 52.1세, 남/녀: 39/27)의 의무기록과 내시경 기록을 검토하였다. 상부 및 하부 위장관 내시경에서 이상이 발견되지 않아 소장질환을 확인하기 위한 목적으로 시행되었으며, 특히 소장출혈의 확인을 위해 시행한 경우가 47명(71.3%)으로 가장 많았다. 이 가운데 궤양 또는 미란이 22예(46.8%), 종양 5예(10.6%), 혈관이형성증 3예(6.4%), 용종 3예(6.4%), 협착이 동반된 궤양 1예(2.1%), 활동성 출혈 1예(2.1%), 정상 소견 12예(25.5%) 등이었다. 이들 가운데 출혈과 관련이 있을 것으로 생각되는 병소는 32예(68.1%)였다. 종양이 발견된 5명에서 수술을 하였는데 위장관간질종양이 4예, 림프관종 1예가 진단되었다. 비특이적 복부 증상으로 시행한 경우의 병변발견율은 42.9%(6/14)였는데, 증상과 관련있는 경우는 1예에 불과하였다. 캡슐내시경 검사로 인한 합병증은 발생하지 않았다. 결론적으로, 캡슐내시경은 소장질환에 대해 안전하고 비침습적인 검사법이며, 소장출혈에 대해 우수한 결과를 보였다. 그러나, 출혈 이외의 복부증상에 대해서는 더 연구가 필요하다.

• Journal of Gastric Cancer
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• 제1권4호
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• pp.215-220
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• 2001

Purpose: The aim of the study was to obtain data on the anatomic and histologic distributions, the clinical features, and the treatment results for patients with primary gastric non-Hodgkin's lymphoma. Materials and Methods: One hundred thirty-two patients who were treated at 8 university hospitals and 2 general hospitals between January 1991 and December 2000 were enrolled to evaluate clinico-pathologic features. Results: The lower one-third of the stomach was the most frequent site ($42\%$), and the most frequent chief complaint was epigastric pain ($54\%$). Gastric resection was performed in 114 cases. Pathologic findings of preoperative endoscopic biopsy specimens from the 114 patients that underwent surgery were a gastric lymphoma in 94 cases ($82\%$), a carcinoma in 15 cases ($13\%$), an ulcer in 4 cases ($4\%$), and a gastrointestinal stromal tumor in 1 case ($1\%$). The stage distributions by Musshoff's criteria were 71 cases ($54\%$) of stage IE, 36 cases ($27\%$) of stage $II_{1}E$, 8 cases ($6\%$) of stage $II_{2}E$, 2 cases ($2\%$) of stage IIIE, and 15 cases ($11\%$) of stage IVE. Histologic gradings by the Working Formulation in were 31 cases ($23\%$) of low grade, 96 cases ($73\%$) of intermediate grade, and 5 cases ($4\%$) of high grade. Chemotherapy-related complications occurred in 25 cases ($22\%$) while operation-related complications occurred in 6 cases ($5\%$). Seventeen patients ($13\%$) only underwent surgery, 19 ($14\%$) had chemotherapy (CTx) and/or radiotherapy (RTx) only, and 96 patients ($73\%$) received surgery and CTx and/or RTx. No substantial differences in survival were found in relation to the different histologic grades and different treatments. The five-year survival was $85\%$ in stage I or II and $47\%$ in stage III or IV (P=0.0000). Conclusion: Pathologic stage appears to be the single most important prognostic indicator. Survival differences according to treatment modalities were not statistically significant. However, the low number of patients treated with various approaches over a long period precludes a firm conclusion.