Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Effect of Grid Keratotomy on Indolent Corneal Ulcers in Dogs

개에서 만성 각막 상피 결손증 치료법으로서의 각막 격자 절개법

  • Ahn, Jae-Sang (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Se-Eun (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Park, Young-Woo (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Ahn, Jeong-Taek (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Yesran (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Eui-Ri (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Seo, Kang-Moon (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University) ;
  • Jeong, Man-Bok (Department of Veterinary Surgery and Ophthalmology, College of Veterinary Medicine, Seoul National University)
  • Accepted : 2011.12.13
  • Published : 2011.12.31
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Abstract

A total of 29 eyes (25 dogs: one eye, 2 dogs: both eyes) with indolent corneal ulcer were treated with grid keratotomy from January 2008 to March 2010. The corneal lesions were reevaluated at 7-14 day intervals. The treatments had been repeated until fluorescein dye was not retained on the cornea and the epithelium did not appear to be loosely attached to the stromal layer. The healing rate of the corneal ulcers was 86.2%. The mean healing time ($mean{\pm}SD$) was $15.92{\pm}9.19$ days, ranged from 7 to 39 days. The lesions of remaining 4 eyes had deteriorated or not improved for more than 6 weeks. In those cases, $3^{rd}$ eyelid flap following grid keratotomy was applied. After 2 weeks, all of the eyes healed by the treatment. The results in this study suggest that grid keratotomy could be an excellent choice as an initial treatment for superficial corneal ulcers in dogs. In the cases of recurrence or to promote healing of the lesions, however, $3^{rd}$ eyelid flap following grid keratotomy is recommended.

2008년 1월부터 2010년 3월까지 만성 각막 상피 결손증으로 서울대학교 부속 동물병원에 내원한 환자 27마리 (25두: 단안, 2두: 양안)를 대상으로 점안마취 하에 격자 각막 절개법을 적용하였다. 처치 후 7-14일 간격으로 재진하였으며, 형광염색 시 음성이고, 각막 표면이 안정화될 때까지 반복 처치하였다. 이중 86.2%에 해당하는 25안에서 각막 궤양이 치유되었으며, 평균 치유기간은 $15.92{\pm}9.19$일 (7-39일)이었다. 병변이 악화되거나 각막 절개법을 최초로 시행 후 6주가 지나도 병변이 치유되지 않는 4안의 경우, 전신마취 하에 각막 절개법 및 제 3 안검 플랩을 적용하였으며, 2주 후 플랩을 제거했을 때, 병변이 모두 치유된 것을 확인하였다. 따라서, 각막 절개법은 만성 각막 상피 결손증에 유용한 치료법이라고 사료되며, 반복적인 처치에도 재발하거나 시술의 성공률을 높이기 위해서는 각막절개법과 제 3 안검 플랩을 함께 실시할 것이 추천된다.

Keywords

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