• 생명과학회지
• /
• 제28권3호
• /
• pp.376-387
• /
• 2018

식물이 접하는 다양한 환경 스트레스(고온, 저온, 냉해, 고염, 가뭄 등) 중에서 물부족(가뭄) 스트레스는 식물의 생장 및 생산성을 저해하는 가장 주요한 요인으로 보고되어 왔다. 그러므로, 물부족 스트레스에 대한 식물의 반응 기작을 명확히 이해하는 것은 물부족 스트레스 저항성이 증가된 유용 작물 개발에 적용될 수 있을 것으로 기대되며, 그 결과 작물 재배 가능 지역의 확대에 기여할 수 있을 것으로 생각된다. 식물의 물부족 스트레스 신호 과정은 크게 식물 호르몬인 앱시스산 의존적인 과정과 비의존적인 과정으로 분류되며, 각각 AREB/ABF, DREB2 전사 조절 인자가 주요한 전사 조절 인자로 참여하여 하위 단계 반응 유전자의 발현 조절에 참여한다. 이러한 AREB/ABF, DREB2 의존적인 regulon에 대한 연구를 통해 물부족 스트레스 신호 과정 중 전사 수준의 조절에 대한 규명이 활발히 이루어지고 있다. 해당 신호 과정에는 전사 수준의 조절뿐만 아니라 인산화, 유비퀴틴화와 같은 번역 후 변형 과정 및 염색질 변형에 의해 매개되는 후성유전학적 조절도 연관되어 있다. 본 총설에서는 현재까지 보고된 물부족 스트레스 신호 전달 과정을, 이와 관련되어 보고된 다양한 신호 전달 단백질들의 기능과 연계시켜 알아보고자 한다. 이러한 물부족 스트레스 신호 전달 과정에 대한 명확한 이해는 향후 유용 내건성 작물 개발을 위한 이론적 기반 구축에 도움이 될 수 있을 것이라 생각된다.

• 한국응급구조학회지
• /
• 제13권1호
• /
• pp.5-18
• /
• 2009

Purpose : The purpose of this survey was to investigate the health status (food intake, exercise, smoking, drinking, stress, social support) of North Korean Refugees in Gwangju metropolitan city and Jeonnam province. Method : Data were collected by self-reported questionnaire from 61 North Korean Refugees from March 20 to April 20, 2005. The data were analyzed by descriptive statistics using SPSS win 12.0 programs. Results: In current health status, 42.7% of the subjects were in poor health. In exercise status, 32.8% of the subjects practiced exercise regular basis but only 13.1% did it 3-4 times per week. In smoking status, 26.2% of the subjects were current smokers and 81% were nicotine dependent. In drinking status, 37.7% of the subjects were current drinkers, 48% were problematic and 17% were alcohol dependent. In stress status, 42.7% of the subjects were in psycho-emotional, 49.2% in physical and 19.6% in behavioral stress. The mean score of social support was 24 out of 54 points showing a little low relatively. Conclusion : These findings showed that the health conditions of Saeteomins were poor relatively. Therefore, health care programs should be started for these Saeteomins in order to improve their health status.

• Structural Engineering and Mechanics
• /
• 제47권6호
• /
• pp.839-856
• /
• 2013

Metallic annular discs with their outer boundary fully constrained are studied with newly derived semi-analytical solutions for the effects of thickness variations under thermal loading and unloading. The plane stress and axisymmetric assumptions were adopted, and the thickness of the disk depends on the radius hyperbolically with an exponent n. Furthermore, it is assumed that the stress state is two dimensional and temperature is uniform in the domain. The solutions include the elastic, elastic-plastic and plastic-collapse behavior, depending on the values of temperature. The von Mises type yield criterion is adopted in this work. The material properties, Young's modulus, yield stress and thermal expansion coefficient, are assumed temperature dependent, while the Poisson's ratio is assumed to be temperature independent. It is found that for any n values, if the normalized hole radius a greater than 0.6, the normalized temperature difference between the elastically reversible temperature and plastic collapse temperature is a monotonically decreasing function of inner radius. For small holes, the n values have strong effects on the normalized temperature difference. Furthermore, it is shown that thickness variations may have stronger effects on the strain distributions when temperature-dependent material properties are considered.

• Nuclear Engineering and Technology
• /
• 제33권6호
• /
• pp.566-584
• /
• 2001

In this paper, the progressive deformation and the creep-fatigue damage for the conceptually designed reactor internals of KALIMER(Korea Advanced Liquid MEtal Reactor) are carried out by using the elastic analysis method in the RCC-MR code for normal operating conditions including the thermal load, seismic load (OBE) and dead weight. The maximum operating temperature of this reactor is 53$0^{\circ}C$ and the total service lifetime is 30 years. Thus, the time- dependent creep and stress-rupture effects become quite important in the structural design. The effects of the thermal induced membrane stress on the creep-fatigue damage are investigated with the risk of the elastic follow-up. To calculate the thermal stress, detailed thermal analyses considering conduction, convection and radiation heat transfer mechanisms are carried out with the ANSYS program. Using the results of the elastic analysis, the progressive deformation and creep-fatigue damages are calculated step by step using the RCC-MR in detail. This paper ill be a very useful guide for an actual application of the high temperature structural design of the nuclear power plant accounting for the time-dependent creep and stress-rupture effects.

• 대한기계학회논문집A
• /
• 제31권2호
• /
• pp.182-189
• /
• 2007

This paper is concerned with the empirical flow stress constitutive equation of steel sheets for an auto-body with the variation of temperature and strain rate. In order to represent the strain rate and temperature dependent behavior of the flow stress at the intermediate strain rates accurately, an empirical hardening equation is suggested by modifying the well-known Khan-Huang-Liang model. The temperature and strain rate dependent sensitivity of the flow stress at the intermediate strain rate is considered in the hardening equation by coupling the strain, the strain rate and the temperature. The hardening equation suggested gives good correlation with experimental results at various intermediate strain rates and temperatures. In order to verify the effectiveness and accuracy of the suggested model quantitatively, the standard deviation of the fitted result from the experimental one is compared with those of the other two well-known empirical constitutive models such as the Johnson-Cook and the Khan-Huang-Liang models. The comparison demonstrates that the suggested model gives relatively well description of experimental results at various strain rates and temperatures.

• 한국세라믹학회지
• /
• 제33권7호
• /
• pp.802-808
• /
• 1996

PbTiO3 thin films were fabricated onto MgO(100) single crystal substrate by reactive D. C magnetron sput-tering of Pb and Ti metal in an oxygen and argon gas mixture. The annealing of the thin films resulted in the decrease of both the c-axis orientation ratio and the lattice parameter. It is well known that the c-axis lattice parameter of thin film is dependent on the Pb/(Pb+Ti)ratio and the residual stress in the film The PbTiO3 thin films with a Pb/(Pb+T) ratio ranging from 0.45 to 0.57 were fabricated and annealed. The structure of the film the c-axis orientation ratio and the lattice parameter were not dependent on the Pb/(Pb+Ti) ratio before and after annealing. These experimental results proved that the decrease of the c-axis lattice parameter under the annealing conditions was due to the relaxation of the intrinsic stress in the film. This relaxation of the intrinsic stress caused the decrease of the c-axis orientation ratio and this phenomenon can be explained by c-axis growth lattice model.

• 한국산학기술학회논문지
• /
• 제8권4호
• /
• pp.821-825
• /
• 2007

본 연구에서는 응력이력 의존적 소성포텐셜을 도입한 단일 경화 모델의 검증을 정규압밀, 약간 과압밀, 심한 과압밀 점토시료에 대하여 수행하였다. 단일 경화 모델은 한계상태 토질역학을 기본으로 비교적 적은 매개변수를 채택하여 최근에 개발된 탄소성 모델이다. 삼축압축시험이 정밀하게 수행되었으며 시험결과는 모델의 예측결과와 전반적으로 잘 부합하였다. 시험결과와의 차이는 단일 경화 모델이 주로 주응력 회전을 강조하기 때문이다. 그러나 소성일 H 및 주응력 회전각 변수를 통하여 지반재료에서 응력이력을 효과적으로 소성일에 반영할 수 있다는 사실이 검증되었다.

• Journal of Welding and Joining
• /
• 제2권2호
• /
• pp.54-61
• /
• 1984

Construction of welding structure is greatly dependent upon welding heat cycle. Fracture toughness is decreased remarkablely due to coarse grained HAZ and inequal residual stress of three dimensions to originate in welding. Post weld heat treatment(PWHT) is carried out to increase the fracture toughness of HAZ and to remove the residual stress. There occur some problem such as toughness decrement and stress relief cracking(SRC) in the coarse grained HAZ subject to the effect of tempering treatment. Therefore, in this paper, the effect of heat inputs affecting cooling rate and PWHT under the no stress on fracture toughness were evaluated by crack opening displacement (COD), SEM and micro-hardness test. Experimental results are as follows; 1. Fracture toughness of weld HAZ is dependent upon weld heat cycle and it is decreased with increment of heat input, but the degree of improvement of fracture toughness after PWHT was linearly increased with heat input. 2. Hardness of the parent metal is not changed, but the softening of coarse grained HAZ is remarkable due to PWHT. 3. Fracture surface of as-weld show the perfect brittle fracture with the cleavage fracture, but after PWHT they appear the ductile fracture surface with dimple.

• 한국산업융합학회 논문집
• /
• 제13권3호
• /
• pp.125-131
• /
• 2010

This study is to give more accurate information by performing the time depend ent analysis to take into account the long-term losses of precast PSC concrete bridge and analyzing the second stress, final camber and cross section stress of precast PSC caused by creep and drying shrinkage. As time goes by, the stress and deformation in the cross section vary continuously by the influence of creep and drying shrinkage. Due to this, the stress redistribution occurs and the internal force variation also happens along the point on the same cross section and with the passage of time.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권7호
• /
• pp.2993-2999
• /
• 2014

Saccharina japonica is a family member of Phaeophyceae (brown macro-alga) and extensively cultivated in China, Japan and Korea. Here, the potential anti-cancer effect of n-hexane fraction of S. japonica was evaluated in SK-Hep1 human hepatocellular carcinoma cells. The N-hexane fraction reduced cell viability and increased the numbers of apoptotic cells in a both dose- and time-dependent manner. Apoptosis was activated by both caspase-dependent and independent pathways. The caspase-dependent cell death pathway is mediated by cell surface death receptors and activated caspase-8 amplified the apoptotic signal either through direct activation of downstream caspase-3 or pro-apoptotic proteins (Bad, Bax and Bak) subsequently leading to the release of cytochrome c. On the other hand, caspase-independent apoptosis appeared mediated by disruption of mitochondrial membrane potential and translocation of AIF to the nucleus where they induced chromatin condensation and/or large-scale DNA fragmentation. In addition, the n-hexane fraction induced endoplasmic reticulum (ER)-stress and cell cycle arrest. The results suggested that potential anti-cancer effects of n-hexane extract from S. japonica on SK-Hep1 cells.