• The Plant Pathology Journal
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• v.37 no.3
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• pp.232-242
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• 2021

Glomerella leaf spot (GLS) is a severe infectious disease of apple whose infective area is growing gradually and thus poses a huge economic threat to the world. Different species of Colletotrichum including Colletotrichum gloeosporioides are responsible for GLS. For efficient GLS control, it is important to understand the mechanism by which the cruciferous crops and C. gloeosporioides interact. Arginine is among one of the several types of amino acids, which plays crucial role in biochemical and physiological functions of fungi. The arginine biosynthesis pathway involved in virulence among plant pathogenic fungi is poorly understood. In this study, CgCPS1 gene encoding carbamoyl phosphate synthase involved in arginine biosynthesis has been identified and inactivated experimentally. To assess the effects of CgCPS1, we knocked out CgCPS1 in C. gloeosporioides and evaluated its effects on virulence and stress tolerance. The results showed that deletion of CgCPS1 resulted in loss of pathogenicity. The ∆cgcps1 mutants showed slow growth rate, defects in appressorium formation and failed to develop lesions on apple leaves and fruits leading to loss of virulence while complementation strain (CgCPS1-C) fully restored its pathogenicity. Furthermore, mutant strains showed extreme sensitivity to high osmotic stress displaying that CgCPS1 plays a vital role in stress response. These findings suggest that CgCPS1 is major factor that mediates pathogenicity in C. gloeosporioides by encoding carbamoyl phosphate that is involved in arginine biosynthesis and conferring virulence in C. gloeosporioides.

• Journal of Korea Society of Industrial Information Systems
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• v.29 no.3
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• pp.121-135
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• 2024

Entrepreneurship is essential in education or courses related to startup. Despite the importance of entrepreneurship, studies on the preceding factors that influence entrepreneurship are insufficient. This study analyzed the relationship between the founder's curiosity and entrepreneurship. In the relationship between curiosity and entrepreneurship, a research model and hypothesis using stress tolerance as a mediation variable was presented and empirically analyzed. As a result of collecting and analyzing data from prospective entrepreneurs and entrepreneurs, it was found that playful inquiry, social curiosity, and pursuit of stimulus had a statistically significant effect on innovation and competition pursuit through stress tolerance. This study is significant in that it analyzed curiosity in multiple dimensions. However, there is a limitation in that the survey is limited to Daegu and Gyeongbuk and the results cannot be generalized.

• The Korean Journal of Nuclear Medicine
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• v.30 no.1
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• pp.112-117
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• 1996

Objective: Standard stress/rest Tc-99m MIBI and T1-201 myocardial perfusion study have some limitations such as stress/rest image overlap for Tc-99m-MIBI, low energy for T1-201 and long period of study time for two separate studies. Separate acquisition rest T1-201/stress Tc-99m MIBI dual isotope study is a potentially efficient myocardial perfusion imaging protocol that combines the high resolution of Tc-99m for stress perfusion assessment and T1-201 for viability assessment. This study assessed the usefulness and diagnostic accuracy for this new approach. Methods: We tried to evaluate sensitivity and specificity of dual isotope separate acquisition protocol in 67 patients. Immediately after resting T1-201 SPECT data was acquired, dipyridamole stress Tc-99m MIBI myocardial perfusion study was performed. Visual analysis was carried out qualitatively with 0 to 3 scoring system for 17 segments of left ventricle in the reconstructed horizontal long axis and short axis slices. Results: Total study was completed within 3 hours. In angiographic correlation, dual isotope SPECT demonstrated high sensitivity(85%) and in a small group of patients, high specificity was also observed (100%). Conclusion: Combined thallium-201/stress Tc-99m MIBI SPECT displayed similiar diagnostic accuracy to protocol using stress/rest Tc-99m MIBI SPECT. This protocol was completed in shorter period than the previous protocols and therefore enhance laboratory throughput and patients convenience.

• Tunnel and Underground Space
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• v.24 no.4
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• pp.297-307
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• 2014

Cavern Thermal Energy Storage system stores thermal energy in caverns to recover industrial waste heat or avoid the sporadic characteristics of renewable-energy resources, and its advantages include high injection-and-extraction powers and the flexibility in selecting a storage medium. In the present study, the structural stability of rock mass pillar between these silo-type storage caverns was assessed using a coupled thermal-mechanical model in $FLAC^{3D}$. The results of numerical simulations showed that thermal stresses due to long-term storage depended on pillar width and had significant effect on the pillar stability. A sensitivity analysis of main factors indicated that the influence on the pillar stability increased in the order cavern depth < pillar width < in situ condition. It was suggested that two identical caverns should be separated by at least one diameter of the cavern and small-diameter shaft neighboring the cavern should be separated by more than half of the cavern diameter. Meanwhile, when the line of centers of two caverns was parallel to the direction of maximum horizontal principal stress, the shielding effect of the caverns could minimize an adverse effect caused by a large horizontal stress.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.3
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• pp.387-395
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• 2013

Recently, several circumferential cracks were found in the control rod drive mechanism (CRDM) nozzles of U.S. nuclear power plants. According to the accident analyses, coolant leaks were caused by primary water stress corrosion cracking (PWSCC). The tensile residual stresses caused by welding, corrosion sensitive materials, and boric acid solution cause PWSCC. Therefore, an exact estimation of the residual stress is important for reliable operation. In this study, finite element simulations were conducted to investigate the effects of the tube geometry (thickness and radius) on the residual stresses in a J-groove weld for different CRDM tube locations. Two different tube locations were considered (center-hole and steepest side hill tube), and the tube radius and thickness variables ($r_o/t$=2, 3, 4) included two different reference values ($r_o$=51.6, t=16.9mm).

• Journal of the Korean Society for Railway
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• v.19 no.4
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• pp.515-525
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• 2016

Parameter analysis of a pretension girder bridge for urban maglev transit was performed to identify the main design parameters and their effect. Girder deflection at mid-span is the most important design criteria of urban maglev transit. Therefore, concrete compressive strength, girder height, girder length, and unbonded tendon length were selected as the design parameters that relate to girder deflection. In addition, tendon layout and unbonded tendon ratios were also considered as design parameters to control the top stress of the pretension girder section at the support. The analysis results show that both the girder height and length are dominant design parameters governing girder deflection, more important than compressive strength and unbounded tendon length. And, sensitivity analysis makes this study suggest design weight value. In terms of stress, a tendon layout that can satisfy the unbounded tendon rule requires an additional tendon or rebar at the upper section to control the tensile stress on top of the section. Therefore, to improve feasibility and constructability in the future, an enhanced unbonded tendon rule considering the load characteristics of the urban maglev system should be studied.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2000.04b
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• pp.439-448
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• 2000

A multi-level design synthesis (MLDA) algorithm for efficiently optimizing orthotropic steel deck bridges is proposed in the paper, because it is usually very difficult to optimize orthotropic steel deck bridges using a conventional single-level (CSL) algorithn since the bridges have a large number of members and show complex structural behaviors. In the proposed MLDS algorithms a coordination method is introduced to divide the bridges into main girders and orthotropic steel decks and decomposition method is also used to reduce the number of design variables of the decks for system level optimization. For efficient optimization of the bridges the MLDS algorithm incorporates the crucial approximation techliques such as constraints deletion and stress reanalysis. The constraint deletion technique for deflection is found to be very useful for the optimization problem of the bridges, since a deflection constraint is usually inactive in the design. Considering the complex system of the bridges, the proposed the efficient stress reanalysis technique may prove to be a very effective method, since it does not require expensive design sensitivity analyses. The applicability and robustness of the MLDS algorithm is demonstrated using various numerical examples and compared with other algorithm presently available so far.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.133-133
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• 2009

It is desirable to choose a high-k material having a large band offset with the tunneling oxide and a deep trapping level for use as the charge trapping layer to achieve high PIE (Programming/erasing) speeds and good reliability, respectively. In this paper, charge trapping and tunneling characteristics of high-k hafnium oxide ($HfO_2$) layer with various thicknesses were investigated for applications of tunnel barrier engineered nonvolatile memory. A critical thickness of $HfO_2$ layer for suppressing the charge trapping and enhancing the tunneling sensitivity of tunnel barrier were developed. Also, the charge trap centroid and charge trap density were extracted by constant current stress (CCS) method. As a result, the optimization of $HfO_2$ thickness considerably improved the performances of non-volatile memory(NVM).

• Transactions of the Korean Society of Mechanical Engineers A
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• v.22 no.2
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• pp.416-427
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• 1998

Unidirectional commingled-yarn-based carbon fiber(CF)/polyamide(PA) 6 composite was fabricated under molding pressures of 0.4, 0.6 and 1.0 MPa to study its flexural deformation and fracture behavior. Fiber/matrix interfacial bonding area became larger with an increase of molding pressure from 0.4 to 0.6 MPa. For molding pressures .geq. 0.6 MPa, good flexural performance of similar magnitudes was attained. For the fracture test, four kinds of notch direction were adopted : edgewise notches parallel (L) and transverse (T) to the major direction of fiber bundles, and flatwise notches parallel(ZL) and perpendicular(ZT) to this direction. Nominal bend strength for L and ZL specimens exhibited high sensitivity to notching. ZL specimens revealed the lowest values of the critical stress intensity factor $K_c$ which was slightly superior to those of unfilled PA6 matrix. Enlargement of the compression area for T specimens was analyzed by means of the rigidity reduction resulting from the fracture occurrence.

• Atmosphere
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• v.17 no.4
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• pp.365-379
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• 2007

Global warming may shift the properties and dynamics of ENSO. We study the changes in ENSO characteristics in a coupled general circulation model, ECHO-G/S. First, we analyse the mean state changes by comparing present day simulation and various high $CO_2$ climates. The model shows a little El Nino-like changes in the sea surface temperature and wind stress in the eastern tropical Pacific. As the mean temperature rises, the ENSO amplitude and the frequency of strong El Ninos and La Nina decrease. The analysis shows that the weakening of the oceanic sensitivities is related to the weakening of ENSO. In addition to the surface changes, the remote subsurface sea temperature response in the western Pacific to the wind stress in the eastern Pacific influences the subsequent ENSO amplitude. However, ENSO amplitude does not show linear response to the greenhouse gas concentrations.