Current technology for radioactive waste disposal facility is operated as part of KURT site characterization in terms of reliability assessment is conducted to expand. In this study, a geological model of KURT surrounding area on the basis of flow characteristics of the site-scale hydrogeological study was about. Distributed in the study area into four boreholes were plotted using the stereo net NS, NW, EW, Low-angle fracture group was able to identify the components of geological models and include top soil layer, belt of weathering, Low-angle fracture zone, fracture zone was divided into. Separated by fracture of the hydraulic test of through the groundwater aquifer that provides the flow hydraulic conductivity and insulation hydraulic affecting the slope of the normal distribution for the size and direction by performing statistical analysis of fracture in the direction of local ns The advantage was confirmed. In addition, Low-angle fracture hydraulic conductivity of the value of 3.61e-07 m/s has a value greater than the major fracture, the fracture zones exist in the base rock and base rock and the hydraulic characteristics of the different methods applied and had to have a different interpretation judged by was.
This study aimed to develop a model of the program for automation measuring the preference of the portraits based on the relationship between the image quality factors and the preferences in the portraits for manufacturers aiming at high utilization of the users. in order to proceed with the evaluation, the image quality measurement was divided into objective and subjective items, and the evaluation was done through image processing and statistical methods. the image quality measurement items can be divided into objective evaluation items and subjective evaluation items. RSC Contrast, Dynamic Range and Noise were selected for the objective evaluation items, and the numerical values were statistically analyzed and evaluated through the program. Exposure, Color Tone, composition of person, position of person, and out of focus were selected for subjective evaluation items and evaluated by image processing method. By applying objective and subjective assessment items, the results were very accurate, with the results obtained by the developed program and the results of the actual visual inspection. but since the currently developed program can be evalua ted only after facial recognition of the person, future research will need to develop a program that can evaluate all kinds of portraits.
This study was performed to evaluate the effect of hemoglobin (Hb) on bone mineral density (BMD) in university students by performing a quantitative analysis. The subjects included healthy university students aged 20 to 30 years. Although osteoporosis has traditionally been considered as a disease of aging women, it is becoming an increasingly concerning male health problem. Diagnosis of osteoporosis is calculated with a quantitative assessment of BMD. Laboratory blood and urine tests are mainly used with low BMD or fragility fractures to identify any possible causes of bone metabolism disorders. In this study, there was no difference in BMD according to gender. The average red blood cell (RBC), Hb, and Hematocrit (HCT) were significantly higher in males (p<0.01). The correlation between lumbar spine, skeletal muscle mass (SMM), and basal metabolic rate (BMR) was statistically significant (p<0.01). Hb showed a 51.7% statistical influence on BMD by multiple regression analysis. These findings are useful to understand the relationship between BMD and Hb; lower Hb level is associated with lower BMD. The Hb level was the strongest predictor of abnormal BMD. In conclusion, this study showed that a low Hb value was significantly correlated with low bone mass, suggesting that a low Hb value is a risk factor for changes in bone turnover that leads to a decrease bone density.
Objectives : Aims of the study were to investigate the physical and mental symptom profiles related with perceived life stress in normal populations. Methods: The study subjects were 186 subjects who visited the Health Promotion Center at National Health Insurance Corporation Ilsan Hospital between July and December, 2000. We measured Life Stress Assessment Scale (LSAS), SCL-90-R (Symptom Check List-90 Revised), and Physical Health Check Questionnaires to evaluate perceived life stress for one year, and physical and mental symptoms. The physical markers related with stress were also measured. According to LSAS scores, we selected two groups from all subjects : Group I (LSAS score with lower 25 percentile) and Group II (LSAS score with higher 75 percentile). Each number of subjects was 46 in Group I and 47 in Group II. We analyzed stasistical significances of study variables between Group I and II. Results : Group II subjects showed higher scores in all subscales of SCL-90-R compared to Group I subjects. Comparing to Group I, Group II subjects complained more physiological symptoms related with anxiety and depression. But there were no statistical differences in the physical markers related stress between two groups. Conclusion: We found that past year-life stress caused various mental and physical symptoms, which didn't develop any physical illness related life stress in normal populations yet.
Zhou, Zhi-Rui;Liu, Shi-Xin;Zhang, Tian-Song;Xia, Jun;Li, Bo
Asian Pacific Journal of Cancer Prevention
/
v.15
no.3
/
pp.1313-1320
/
2014
Introduction: Although most prostate cancers initially respond to castration with luteinizing hormonereleasing analogues or bilateral orchiectomy, progression eventually occurs. Based on the exciting results of several randomized controlled trials (RCTs), it seems that patients with metastatic castration-resistant prostate cancer (mCRPC) might benefit more from treatment withabiraterone. Therefore we conducted a systematic review to evaluate the efficacy and toxicity of abiraterone in the treatment of mCRPC. Methods: Literature was searched from Embase, PubMed, Web of Science, and Cochrane Library up to July, 2013. Quality of the study was evaluated according to the Cochrane's risk of bias of randomized controlled trial (RCT) tool, then the Grading of Recommendations Assessment, Development and Evaluation (GRADE) System was used to rate the level of evidence. Stata 12.0 was used for statistical analysis. Summary data from RCTs comparing abiraterone plus prednisone versus placebo plus prednisone for mCRPC were meta-analyzed. Pooled hazard ratios (HRs) for overall survival (OS), radiographic progression-free survival (RPFS) and time to PSA progression (TTPP); Pooled risk ratios (RR) for PSA response rate, objective response rate and adverse event were calculated. Results: Ten trials were included in the systematic review; Data of 2,283 patients (1,343 abiraterone; 940 placebo) from two phase 3 trials: COU-AA-301 and COU-AA-302 were meta-analyzed. Compared with placebo, abiraterone significantly prolonged OS (HR, 0.74; 95% confidence interval [CI], 0.66 to 0.84), RPFS (HR, 0.59; 95% CI, 0.48 to 0.74) and time to PSA progression (HR, 0.55; 95% CI, 0.43 to 0.70); it also significantly increased PSA response rate (RR, 3.63; 95% CI, 1.72 to 7.65) and objective response rate (RR, 3.05; 95% CI, 1.51 to 6.15). This meta-analysis suggested that the adverse events caused by abiraterone are acceptable and can be controlled. Conclutios: Abiraterone significantly prolonged OS, RPFS and time to progression patients with mCRPC, regardless of prior chemotherapy or whether chemotherapy-na$\ddot{i}$ve, and no unexpected toxicity was evident. Abiraterone can serve as a new standard therapy for mCRPC.
Seo, Yongsik;Whang, Kum;Pyen, Jinsu;Choi, Jongwook;Kim, Joneyeon;Oh, Jiwoong
Journal of Korean Neurosurgical Society
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v.63
no.5
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pp.649-656
/
2020
Objective : Unclear mental state is one of the major factors contributing to diagnostic failure of occult skeletal trauma in patients with traumatic brain injury (TBI). The aim of this study was to evaluate the overlooked co-occurring skeletal trauma through whole body bone scan (WBBS) in TBI. Methods : A retrospective study of 547 TBI patients admitted between 2015 and 2017 was performed to investigate their cooccurring skeletal injuries detected by WBBS. The patients were divided into three groups based on the timing of suspecting skeletal trauma confirmed : 1) before WBBS (pre-WBBS); 2) after the routine WBBS (post-WBBS) with good mental state and no initial musculoskeletal complaints; and 3) after the routine WBBS with poor mental state (poor MS). The skeletal trauma detected by WBBS was classified into six skeletal categories : spine, upper and lower extremities, pelvis, chest wall, and clavicles. The skeletal injuries identified by WBBS were confirmed to be simple contusion or fractures by other imaging modalities such as X-ray or computed tomography (CT) scans. Of the six categorizations of skeletal trauma detected as hot uptake lesions in WBBS, the lesions of spine, upper and lower extremities were further statistically analyzed to calculate the incidence rates of actual fractures (AF) and actual surgery (AS) cases over the total number of hot uptake lesions in WBBS. Results : Of 547 patients with TBI, 112 patients (20.4 %) were presented with TBI alone. Four hundred and thirty-five patients with TBI had co-occurring skeletal injuries confirmed by WBBS. The incidences were as follows : chest wall (27.4%), spine (22.9%), lower extremities (20.2%), upper extremities (13.5%), pelvis (9.4%), and clavicles (6.3%). It is notable that relatively larger number of positive hot uptakes were observed in the groups of post-WBBS and poor MS. The percentage of post-WBBS group over the total hot uptake lesions in upper and lower extremities, and spines were 51.0%, 43.8%, and 41.7%, respectively, while their percentages of AS were 2.73%, 1.1%, and 0%, respectively. The percentages of poor MS group in the upper and lower extremities, and spines were 10.4%, 17.4%, and 7.8%, respectively, while their percentages of AS were 26.7%, 14.2%, and 11.1%, respectively. There was a statistical difference in the percentage of AS between the groups of post-WBBS and poor MS (p=0.000). Conclusion : WBBS is a potential diagnostic tool in understanding the skeletal conditions of patients with head injuries which may be undetected during the initial assessment.
Park, Seok Jae;Choi, Wae Ho;Kim, Yo Suk;Shin, Yeong-Soo
Journal of Korean Society of Steel Construction
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v.13
no.5
/
pp.567-575
/
2001
In order to consider statistical properties of probability variables used in the structural analysis the conventional approach using the safety factor based on past experience usually estimated the safety of a structure Also the real structures could only be analyzed with the error in estimation of loads material characters and the dimensions of the members. But the errors should be considered systematically in the structural analysis Safety of structure could not precisely be appraised by the traditional structural design concept Recently new aproach based on the probability concept has been applied to the assessment of structural safety using the reliability concept Thus the computer program by the Probabilitstic FEM is developed by incorporating the probabilistic concept into the conventional FEM method. This paper estimated for the reliability of a plane stress structure by Advanced First-Order Second Moment method using von Mises, Tresca and Mohr-Coulomb failure criterions. Verification of the reliability index and failure probability of attained by the Monte Carlo Simulation method with the von Mises criterion were same as PFEM, but the Monte Carlo Simulation were very time-consuming. The variance of member thickness and load could influence the reliability and failure probability most sensitively among the design variables from the results of the parameter analysis. The proper failure criterion according to characteristic of materials must be used for safe design.
Kim, Byung-Sik;Kim, Bo-Kyung;Kyung, Min-Soo;Kim, Hung-Soo
Journal of Korea Water Resources Association
/
v.41
no.4
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pp.379-394
/
2008
Recently, extreme precipitation events beyond design capacity of hydraulic system have been occurred and this is the causes of failure of hydraulic structure for flood prevention and of severe flood damage. Therefore it is very important to understand temporal and spatial characteristics of extreme precipitation events as well as expected changes in extreme precipitation events and distributional characteristics during design period under future climate change. In this paper, climate change scenarios were used to assess the impacts of future climate change on extreme precipitation. Furthermore, analysis of future extreme precipitation characteristics and I-D-F analysis were carried out. This study used SRES B2 greenhouse gas scenario and YONU CGCM to simulate climatic conditions from 2031 to 2050 and statistical downscaling method was applied to establish weather data from each of observation sites operated by the Korean Meteorological Administration. Then quantile mapping of bias correction methods was carried out by comparing the simulated data with observations for bias correction. In addition Modified Bartlett Lewis Rectangular Pulse(MBLRP) model (Onof and Wheater, 1993; Onof 2000) and adjust method were applied to transform daily precipitation time series data into hourly time series data. Finally, rainfall intensity, duration, and frequency were calculated to draw I-D-F curve. Although there are 66 observation sites in Korea, we consider here the results from only Seoul, Daegu, Jeonju, and Gwangju sites in this paper. From the results we found that the rainfall intensity will be increased and the bigger intensity will be occurred for longer rainfall duration when we compare the climate conditions of 2030s with present conditions.
The purpose of this study was to describe mother -infant interacting behavior patterns related to newborn infant feeding and to explore the mother's cultural belief about their infant. The data collection was conducted by observation and interview. Twenty-five mothers and their newborn infants who were normally delivered and were also planned to breast feed were comprised as the subjects of this study. All subjects were interviewed and observed individuaily at 1 to 5 days after the delivery at the hospital, mid -wife's clinic, Maternal Child Health Center and their home throughout the country from remote area to big city, The observation data were recorded with symbolic letter on a recording sheet newly developed as a result of preliminary study. The interview data were taperecorded and then recorded in narrative form. Mother - infant interaction behaviors in early feeding period were analyzed based on 19 analytic sub-categories and their composing elements. Unit of analysis were mother, infant and mother -infant dyad. 8 analytic categories draw from the data. Each were preparation, instrument, interaction inducing, evaluation referred to mother's behavior, preparation, instrument, interaction inducing referred to infant's behavior and synchronic behaviors referred to mother - infant dyad. Frequencies of behavior items based on the categories were converted to percent. The result showed that in mother's preparation behavior, the breast condition of Korean mother can be an affecting factor for mother - infant interaction during feeding, and vocalization behavior was observed most frequently in interaction inducing behavior while the least frequent behavior observed was contacting. Subcultural characteristics of mother - infant interaction behaviors were analyzed for their relationships between groups of mothers who have lived in remote area vs urban area, and who were multipara vs primipara. Using a chi -square test, there were statistically significant relationships in the activity of psychological readiness in preparation behavior and the movement of extremities for the position of instrumental behavior in both groups. However, interaction inducing behaviors were not related with statistical significance in any set of groups. Accomplishment of marriage, bonding and emotional mediation of family members were the categories related to mother's cultural belief about the infant in aspect of functional values. Infant at birth is considered little more than a biological organism without social capabilities. Although the newborn infant is still be attached to his mother, he makes his mother extend her territoriality. The mother's interacting behavior toward her infant based on those beliefs appeared task oriented, separative behavioral series. On the other hand, it was seen that infant reacted independently to his mother's behavior by the in-nate perceptual abilities. Those independent behavioral series of mother and infant on the feeding situation were synchronized at any moment. Nurses are In a unique position to teach mothers about their infant's capabilities and help reducing some of uncertainty about infant's behaviors. Study results indicated that the informations infant's social capabilities and breast feeding should be given to the mothers. The results of this study have several implications for nursing. First, the study results will be used as fundamental resources for the development of the assessment tool about the early mother - infant interaction. Second, the results could be a relevant information in the fied. I of maternal child nursing education as real and useful data. Third, the behavioral patterns of early mother - infant interaction which were classified based on the qualitative analysis could be used for nursing theory development as very fundamental data.
Trigeminal nerve injuries due to invasive dental procedures such as implant surgery and extraction is one of the most serious issues in dentistry and may provoke medico-legal problems. Thus, for objective and reliable assessment of nerve injury, a need of QST (quantitative sensory testing) is emphasized and thermal threshold test is an essential part of QST, reported to have acceptable reliability in the orofacial region. This pilot study aimed to evaluate thermal thresholds for limited cases of trigeminal nerve injures. The study investigated 18 clinical cases with trigeminal nerve injuries who visited Department of Oral Medicine, Dankook Univeristy Dental Hospital during the period from May 2011 to Oct 2012. Thermal thresholds was measured by Thermal Sensory Analyzer, TSA-II (Medoc, Israel). Their CDT(cold detection threshold) was significantly decreased in the affected sides compared to the unaffected sides. Other parameters such as WDT(warm detection threshold), CPT(cold pain threshold) and HPT(heat pain threshold) did not show statistical difference between the affected and unaffected sides. Further researches are required to compare thermal thresholds relative to types of nerve deficits such as thermal hyper- or hypoesthesia and hyper- or hypoalgesia for larger sample.
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