• Journal of Nutrition and Health
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• v.42 no.3
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• pp.221-233
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• 2009

Korea's aging population has been remarkably increased. They want to have not only extension of life expectancy but also improving quality of life. To maintain the quality of life, it is essential to have good nutrition. However, nutritional status of elderly in Korea has problems qualitatively and quantitatively. Risk factors for poor nutrition are advanced age, woman, living alone and low economic status. Another risk factor in rural area is season because seasonal changes can affect food intake of elderly. Thus this study surveyed the health status and dietary intakes of elderly by season in rural area. In this study, the elderly were grouped as group 1 {elderly who have one risk factor for chronic diseases (obesity, hypertension, dyslipidemia, diabetes)} and group 2 (elderly who have more than 2 risk factors). Can-Pro 3.0 was used for dietary data analysis and SPSS 12.0 program was used for statistical analysis. Obesity had the highest percentage 62%, followed by hypertension 59.5%, dyslipidemia 21.5% and diabetes 11.6%. Obesity, hypertension, and dyslipidemia were high in winter and WHR, diabetes and anemia were high in summer. Mean intakes of energy and nutrients were less than RI. Nutrients which were changed most by season were vitamin A and Vitamin C. Intakes of calcium and folic acid were less than recommended in summer. The ratio of CPF for carbohydrate was higher and fat was lower than recommended. In conclusion, the nutrient intake of Group 2 was better in quality but Group 1 was better in quantity. Nutrient intakes were poor in summer. In rural area, more careful nutritional assesment and management are needed for aged population, especially in summer.

• Journal of Korean Neurosurgical Society
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• v.42 no.1
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• pp.1-5
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• 2007

Objective : We studied whether frontal skull base fracture has an impact on the occurrence and recovery of anosmia and/or ageusia following frontal traumatic brain injury (TBI). Methods : Between May 2003 and April 2005, 102 consecutive patients who had hemorrhage or contusion on the frontal lobe base were conservatively treated. Relevant clinical and radiographic data were collected, and assessment of impaired smell and taste sensation were also surveyed up to at least 12 months post-injury. Results : Among 102 patients, anosmia was noted in 22 (21.6%), of whom 10 had ageusia at a mean 4.4 days after trauma. Bilateral frontal lobe injuries were noted in 20 of 22 patients with anosmia and in all 10 patients with ageusia. Frontal skull base fracture was noted in 41 patients, of whom 9 (21.4%) had anosmia and 4 (9.5%) had ageusia. There was no statistical difference in the occurrence of anosmia and ageusia between patients with or without fracture. Of the 22 patients with anosmia, recovery from anosmia occurred in nine (40.9%) at the interval of 6 to 24 months after trauma, of whom six had frontal skull base fracture and three were not associated with fracture. Recovery of anosmia was significantly higher in patients without fracture than those with fracture (p<0.05). Recovery from ageusia occurred in only two of 10 patients at the interval of 18 to 20 months after trauma and was not eminent in patients without fracture. Conclusion : One should be alert and seek possibile occurrence of the anosmia and/or ageusia following frontal TBI. It is suggested that recovery is quite less likely if such patients have fractures on the frontal base, and these patients should wait for at least 6 to 18 months to anticipate such recovery if there is no injury to the central olfactory structures.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.6
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• pp.447-456
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• 2014

Until now, a disease-modifying therapy (DMT) that has an ability to slow or arrest Alzheimer's disease (AD) progression has not been developed, and all clinical trials involving AD patients enrolled by clinical assessment alone also have not been successful. Given the growing consensus that the DMT is likely to require treatment initiation well before full-blown dementia emerges, the early detection of AD will provide opportunities to successfully identify new drugs that slow the course of AD pathology. Recent advances in early detection of AD and prediction of progression of the disease using various biomarkers, including cerebrospinal fluid (CSF) $A{\beta}_{1-42}$, total tau and p-tau181 levels, and imagining biomarkers, are now being actively integrated into the designs of AD clinical trials. In terms of therapeutic mechanisms, monitoring these markers may be helpful for go/no-go decision making as well as surrogate markers for disease severity or progression. Furthermore, CSF biomarkers can be used as a tool to enrich patients for clinical trials with prospect of increasing statistical power and reducing costs in drug development. However, the standardization of technical aspects of analysis of these biomarkers is an essential prerequisite to the clinical uses. To accomplish this, global efforts are underway to standardize CSF biomarker measurements and a quality control program supported by the Alzheimer's Association. The current review summarizes therapeutic targets of developing drugs in AD pathophysiology, and provides the most recent advances in the clinical utility of CSF biomarkers and the integration of CSF biomarkers in current clinical trials.

• The Journal of the Korea Contents Association
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• v.18 no.3
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• pp.601-610
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• 2018

This case study analyzed the effect of capstone design on students' competence and class satisfaction. Three subjects developed in S university were analyzed, and 92 students participated. Results show that the lesson structure of the capstone design was developed to provide students with problem solving competence and practical business skills through hands-on experience. In addition, the students' competence was enhanced, and their satisfaction in class was very high. Statistical results show that, compared to the existing classes, class satisfaction in capstone design improved significantly. Considering the foregoing results, this study suggested that for the capstone design, the lesson structure and method need to be diversified to provide more opportunities for students to participate and become active. The assessment procedure and method also have to be more objective to lessen subjectivity and to increase class satisfaction in capstone design.

• Journal of the Korean Society for Railway
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• v.11 no.1
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• pp.107-113
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• 2008

As it recently appears that LCC (Life Cycle Cost) analysis may be considered as an essential method for economic evaluation of infrastructures. Many researches have been made to assess LCC of each facility based on reasonable methods. However, expected maintenance repair cost must be reasonably estimated to enhance the reliability of LCC analysis through systematic and rational methods. This study is intended to propose a rational approach to reliability-based LCC analysis of high-speed railway steel bridges considering lifetime corrosion and fatigue damage. However in Korea, since high speed railway steel bridges are only recently constructed, no direct statistical data are available for the account of the maintenance cost and thus their maintenance characteristics are not clear yet. In this paper, for the assessment of expected maintenance/repair cost, the fatigue system reliability analysis incorporating the corrosion effect is proposed by considering the corrosion and fatigue damage using measured data of high speed railway steel bridges. A model proposed by Rahgozar, of at for fatigue notch factor considering the corrosion effect is used in order to incorporate the corrosion effect into the fatigue strength reduction and S-N curve. Finally, the effectiveness of LCC model proposed for high-speed railway steel bridges is demonstrated by a numerical example.

• The Korean Journal of Applied Statistics
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• v.24 no.5
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• pp.931-939
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• 2011

In practice, thresholds are determined by the two subjective assessment methods in a generalized pareto distribution of mean extreme function(MEF-graph) or Hill-graph. To remedy the problem of subjectiveness of these methods, we propose an alternative method to determine the threshold based on the robust statistics. We compared the MEF-graph, Hill-graph and our method through VaRs on the Korean stock market data from January 5, 1987 to August 3, 2009. As a result, the VaR based on the proposed method is not much different from the existing methods, and the standard deviation of VaR for our method was the smallest. The results show that our method can be a promising alternative to determine thresholds of the generalized pareto distributions.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.1
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• pp.41-49
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• 2017

Process quality control, which prevents problems and risks that may occur in products and processes, has been recognized as an important issue, and SPC techniques have been used for this purpose. Process Capability Index (PCI) is useful Statistical Process Control (SPC) tool that is measure of process diagnostic and assessment tools widely use in industrial field. It has advantage of easy to calculate and easy to use in the field. $C_p$ and $C_{pk}$ are traditional PCIs. These traditional $C_p$ and $C_{pk}$ were used only as a measure of process capability, taking into account the quality variance or the bias of the process mean. These are not given information about the characteristic value does not match the target value of the process and this has the disadvantage that it is difficult to assess the economic losses that may arise in the enterprise. Studies of this process capability index by many scholars actively for supplement of its disadvantage. These studies to evaluate the capability of situation of various field has presented a new process capability index. $C_{pm}$ is considers both the process variation and the process deviation from target value. And $C_{pm}{^+}$ is considers economic loss for the process deviation from target value. In this paper we developed an improved Expected Loss Capability Index using Reflected Normal Loss Function of Spring. This has the advantage that it is easy to realistically reflect the loss when the specification is asymmetric around the target value. And check the correlation between existing traditional process capability index ($C_{pk}$) and new one. Finally, we propose the criteria for classification about developed process capability index.

• Fisheries and Aquatic Sciences
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• v.5 no.3
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• pp.219-228
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• 2002

Based on the five-year (October 1992 through September 1997) Topex/Poseidon altimeter measurements, we describe the statistical characteristics of the eddy variability in the East Sea in terms of sea surface height anomaly, slope variability, and eddy kinetic energy (EKE). The sea surface height anomalies in the East Sea are produced with standard corrections from Topex/Poseidon measurements. In order to eliminate the high frequency noise in the sea surface height anomaly data, the alongtrack height anomaly data was filtered by about 40 km low-pass Lanczos filter based on Strub et al. (1997) and Kelly et a1. (1998). We find that there exists a distinct spatial contrast of high eddy variability in the south and low eddy energy in the north, bordering the Polar Front. In the northwestern area $(north\;of\;39^{\circ}N\;and\;west\;of\;133^{\circ}E)$ from the Polar Front where the eddies frequently appear, the EKE is also considerabel. The high kinetic energy in the southern East Sea reveals a close connection with the paths of the Tsushima Warm Current, suggesting that the high variability in the south is mainly generated by the baroclinic instability process of the Tsushima Warm Current. This finding is supported by other studies (Fu and Zlontnicki, 1989; Stammer, 1997) wh.ch have shown the strong eddy energy coupled in the major current system. The monthly variation of the EKE in both areas of high and low eddy variability shows a strong seasonality of a high eddy kinetic energy from October to February and a relatively low one from March to September. The sequential pattern of wind stress curl shows resemblance with those of monthly and seasonal EKE and the two sequences have a correlation of 0.82 and 0.67, respectively, providing an evidence that wind stress curl can be the possible forcing for the monthly and seasonal variation of the EKE in the East Sea. The seasonality of the EKE also seems to correlate with the seasonality of the Tsushima Warm Current. There also exists the large spatial and interannual variabilities in the EKE.

• Journal of Acupuncture Research
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• v.25 no.1
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• pp.187-197
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• 2008

Objectives : The purpose of this study was to assess the reproducibility of measurement of facial skin furrows using a facial skin photographing system. Methods : Subjects were 19 patients who visited the department of acupuncture and moxsibustion, at the hospital of Oriental medical college, at Daegu Haany University for the cosmetic acupuncture treatment during August 2007 to 31th August 2007. The facial skin photograph of each participant was analyzed a total of six times in two days using DM-3(a facial skin photographing system). The square and counts of skin furrows were also measured for each one. As the statistical method, Pearson's correlation coefficient and repeated measured ANOVA were used. Results : The Pearson's correlation coefficient, it showed significantly high correlation in both the square and count of skin furrows for each analysis time. Repeated measured ANOVA showed no significant differences among analyses in both square and count of skin furrows. Conclusions : This study reveales that the measurement of the count and square of facial skin furrows by facial skin photograph analysis has high reproducibility. DM-3(a facial skin photographing system) can be useful for the evaluation of facial skin furrows in facial cosmetic acupuncture.

• Journal of Korean Academy of Nursing
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• v.45 no.5
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• pp.627-640
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• 2015

Purpose: The objective of this systematic review was to assess the effects of family support programs on caregiving burden, depression, and stress in family caregivers of people with dementia. Methods: A literature search was conducted of electronic databases to identify randomized controlled studies with family support programs done between 2000 and 2014. Studies published in English and/or Korean were included for the analysis with search strategies adapted from the Cochrane Dementia and Cognitive Improvement Group. Studies were rated for quality assessment by two independent reviewers using the appraisal checklist developed by Cochrane Reviews and Dissemination. Of 8,334 articles identified in the literature search, full texts of 76 articles that met the inclusion criteria were reviewed and 38 were found to include relevant outcomes. Results: Results from selected studies were pooled in statistical meta-analysis using Review Manager Software and heterogeneity between combined studies was assessed using the Chi-square test. Meta-analysis showed that the effect sizes of family caregiver support programs were small to medium for categories of caregiving burden (Hedge's g= - 0.17, 95% CI= - 0.30~ - 0.04), depression (Hedge's g= - 0.30, 95% CI= - 0.40~ - 0.20), and stress (Hedge's g= - 0.39, 95% CI= - 0.52~ - 0.25). Conclusion: The review results indicate that a support programs can assist family caregivers in reducing their psycho-emotional distress.