• Journal of Chest Surgery
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• 제54권4호
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• pp.266-278
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• 2021

Lobectomy is the standard treatment for early non-small cell lung cancer. Various surgical techniques for lobectomy have been developed, and minimally invasive thoracic surgery, such as video-assisted thoracic surgery or robot-assisted thoracic surgery, has been considered as an alternative to conventional open thoracotomy. The recently robotic lobectomy technique has developed since the first case series was published in 2002. Several studies have reported that robotic lobectomy has comparable oncologic and perioperative outcomes to those of video-assisted thoracic surgery lobectomy and open lobectomy. However, robotic lobectomy remains a challenge for surgeons because of the steep learning curve, reduced tactile sensation, difficulty in port placement, and challenges in cooperation between the surgeon and assistant. Many studies have reported on robotic lobectomy, but few have presented surgical techniques for robotic lobectomy. In this article, the surgical techniques and optimal performance of robotic lobectomy are described in detail for all 5 types of lobectomy for surgeons beginning with robotic lobectomy.

• 대한두개안면성형외과학회지
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• 제22권3호
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• pp.135-140
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• 2021

Background: Wide surgical excision is the gold standard for basal cell carcinoma (BCC) treatment. Typically, resection requires a safety margin ≥ 4 mm. We aimed to confirm BCC excisions' cancer recurrence rate and safety on the facial region with new safety margins. Methods: We included patients with primary BCC on the facial region who underwent wide excision with 2- or 3-mm safety margins at our institution between January 2010 and December 2018. Medical records were reviewed to confirm the epidemiology and surgical information. Recurrence was confirmed by physical examination through regular 6-month follow-up. Results: We included 184 out of 233 patients in this study after applying the exclusion criteria. The mean age and follow-up period were 71.2±10.2 years and 29.3±13.5 months, respectively. The predominantly affected area was the nose (95 cases); a V-Y advancement flap was the most commonly used surgical method. There were two cases of recurrence in the 2 mm margin group and one recurrence in the group resected with 3 mm margins. Conclusion: In this large cohort study, we found 2-3 mm excision margins can yield enough safety in facial BCCs. The recurrence rates were found to be comparable with those reported after wider margins.

• 신재생에너지
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• 제18권2호
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• pp.26-39
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• 2022

Considering the recent substantial increase in national research and development (R&D) budgets in the energy sector there has been increased Interest in the effectiveness of government R&D investments. We conducted a case study to calculate the allowable scale and effectiveness of R&D investment by calculating the direct performance improvement effect resulting from R&D investment as an economic value. Using conditions that existed prior to R&D investments as a reference, five cases in which performance improved due to R&D investments were compared and analyzed. The government's financial investment is increasing rapidly in line with the establishment of the national hydrogen roadmap. R&D is needed to enhance the current low technology readiness level of hydrogen fuel cells compared to solar and wind energy fields. Therefore, an R&D project to improve the performance of the fuel cell system was selected as this case study's subject. Using the results in this study, the allowable level of investment in the task unit of national R&D projects could be calculated. Moreover, it is advisable to provide a standard for rational decision making for new R&D investments since it is possible to determine investment priorities among a large number of candidates.

• 공업화학전망
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• 제24권4호
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• pp.52-61
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• 2021

2019년 정부의 '수소경제 활성화 로드맵' 발표 후 수소연료전지 보급에 추진 동력원이 되었고, 2020년 2월 '수소경제 육성 및 수소안전관리에 관한 법률'이 세계 최초로 제정되면서 수소연료전지의 안정적인 보급 확산을 견인하고 있다. 수소안전관리에 의한 법률에 의해 수소용품 4종 및 수소사용시설 1종에 대한 KGS Code 3종(수소추출설비, 고정형 연료전지, 수소연료사용시설)이 2021년 7월 제정되었고, 8월 2종(수전해설비, 지게차용 이동형 연료전지)이 추가 제정되어 2022년 2월부터 수소용품 및 시설에 대한 안전관리가 시작된다. 연료전지의 안정적인 보급을 위해서는 국내에 적합한 안전기준 개발이 필수적이다. 또한 신규 출현되는 제품 및 시설의 개발·보급 시기에 맞추어 안전 기준 개발이 병행되어야 할 것이다. 본고에서는 고정형 및 이동형 연료전지의 국내외 안전기준 분석 및 위험요소 분석 등을 통한 연료전지 안전기준 개발 현황을 소개하고자 한다.

• 한국식품영양학회지
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• 제35권5호
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• pp.359-368
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• 2022

In this study, the quality characteristics of kimchi, such as its salinity, pH, and acidity, were measured and compared, and the HT-29 human colon cancer cells were used to show the anticancer effects of kimchi. The kimchi samples used herein included standard kimchi (SK), turnip kimchi (TK), and turnip-powder-added kimchi (TPK). The measured pH and acidity of TK and TPK showed no significant differences with those of SK. Compared to SK and TK, TPK had higher DPPH scavenging activity and higher total flavonoid content, confirming its antioxidant activity. The cancer cell growth inhibition rates of TK and TPK were significantly higher than that of SK. In HT-29 cells treated with TPK, the mRNA expression of Bcl-xL, an anti-apoptosis-related gene, was lower, and the mRNA expressions of the apoptosis-related genes Bax, Bad, and caspase-9 were higher. TPK showed significantly higher levels of mRNA expressions for the cell-cycle-related genes p53 and p21 than the other samples, in addition to suppression effects on cancer cell proliferation. Compared to SK, TK and TPK suppressed the growth of colon cancer cells and showed higher anticancer effects. Therefore, it is shown that kimchi with added turnip powder had high anticancer effects.

• 한국수소및신에너지학회논문집
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• 제34권4호
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• pp.369-380
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• 2023

There is no clear standard for estimating the power distribution of fuel cells and batteries to meet the required power in hydrogen electric vehicles. In this study, a hydrogen electric vehicle simulation model equipped with a vehicle electric component model including a fuel cell system was built, and a power distribution strategy between fuel cells and batteries was established. The power distribution model was operated through two control strategies using step control and fuzzy control, and each control strategy was evaluated through data derived from the simulation. As a result of evaluation through the behavior data of state of charge, fuel cell current and balance of plant, fuzzy control was evaluated as a proper strategy in terms of control stability and durability.

• IMMUNE NETWORK
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• 제22권1호
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• pp.9.1-9.23
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• 2022

In the past few decades, biological drugs and small molecule inhibitors targeting inflammatory cytokines, immune cells, and intracellular kinases have become the standard-of-care to treat autoimmune diseases. Inhibition of TNF, IL-6, IL-17, and IL-23 has revolutionized the treatment of autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis, and psoriasis. B cell depletion therapy using anti-CD20 mAbs has shown promising results in patients with neuroinflammatory diseases, and inhibition of B cell survival factors is approved for treatment of systemic lupus erythematosus. Targeting co-stimulatory molecules expressed on Ag-presenting cells and T cells is also expected to have therapeutic potential in autoimmune diseases by modulating T cell function. Recently, small molecule kinase inhibitors targeting the JAK family, which is responsible for signal transduction from multiple receptors, have garnered great interest in the field of autoimmune and hematologic diseases. However, there are still unmet medical needs in terms of therapeutic efficacy and safety profiles. Emerging therapies aim to induce immune tolerance without compromising immune function, using advanced molecular engineering techniques.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 심포지엄 논문집 정보 및 제어부문
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• pp.218-220
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• 2005

In this paper, we have designed a home network system based on WIPI. WIPI (Wireless Internet Platform for Interoperability) is the standard specification for the mobile platform made by the Mobile Platform Special subcommittee of the Korea Wireless Internet Standardization Forum(KWISP). The system consists of three parts - a server, client, and simulator, and all parts are developed with JAVA. People can control household appliances anytime, anywhere by using cell phones which can use the wireless Internet, so the system offers convenience to people.

• Bulletin of the Korean Chemical Society
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• 제32권8호
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• pp.2761-2764
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• 2011

A new Ruddlesden-Popper phase $NdSr_2MnCrO_7$ has been prepared by the standard ceramic method. The powder X-ray diffraction studies suggest that the phase crystallizes with tetragonal unit cell in the space group I4/mmm. The electrical transport properties show that the phase is an electrical insulator and the electrical conduction in the phase occurs by a 3D variable range hopping mechanism. The magnetic studies suggest that the ferromagnetic interactions are dominant.

• 한국통신학회:학술대회논문집
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• 한국통신학회 1986년도 추계학술발표회 논문집
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• pp.91-94
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• 1986

In this paper, a servo motor control IC for VTR is developed using standard cell library. All the cells are designed by single metal and the 3um design rule. A desinged circuit consists of circuits which generates a switching pulse and a control reference signal in VTR. The operation of VTR chip is verified by COSMOS simulator. Finally, layout is drawn by YOSELA.