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Technology Level Evaluation Based On Technology Growth Model and Its Implication - In Case of 'Biochip and Biosensor Technology' (기술성장모형에 기반을 둔 기술수준평가 결과 및 시사점 - 바이오칩.센서기술을 중심으로)

  • Han, Min-Kyu;Kim, Byoung-Soo;Ryu, Ji-Yeon;Byeon, Soon-Cheon
    • Journal of Korea Technology Innovation Society
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    • v.13 no.2
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    • pp.252-281
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    • 2010
  • In this paper, we analyze the result of the Technology Level Evaluation of 'Biochip and biosensor (BB) Technology' consisted of 3 sub-categorized technologies; biochip sensing (BS), lab on a chip and high-efficient customized health care technology. As an analysis tool, authors used a delphi (a repeated survey) and dynamic methodology with technology growth model to overcome limits of previous evaluations. As a result, levels of BB were evaluated 51.5% (Korea) and 75.1% (US), and the technology gap between two countries was 6.1 yrs. In 2013, these levels were expected to change to 60.1% (Korea), 78.4% (US) and 4.3 yrs, respectively. In comparison with other biotechnology, the gap of BB was smaller and expected to catch up with US faster. In the case of sub-categorized technologies, they showed the smallest gap and would have faster catch-up speed than other sub-categorized technologies in the Biotechnology field. Based on the result of the survey, relative superiority of BB in Korea was originated from competent researchers and research fund, but weak basic science would be weak points. We think that BB's characteristic as an emerging technology and concentrated research activities on BB are additional strong points. This research proposes the supporting and supplemented points to promote the BB in Korea.

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Dislodgement resistance of modified resin-bonded fixed partial dentures utilizing tooth undercuts: an in vitro study

  • Doh, Re-Mee;Lee, Keun-Woo
    • The Journal of Advanced Prosthodontics
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    • v.1 no.2
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    • pp.85-90
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    • 2009
  • STATEMENT OF PROBLEM. Over the years, resin-bonded fixed partial dentures (RBFPDs) have gone through substantial development and refinement. Several studies examined the biomechanics of tooth preparation and framework design in relation to the success rate of RBFPDs and considered retention and resistance form essential for increase of clinical retention. However, these criteria required preparations to be more invasive, which violates not only the original intentions of the RBFPD, but may also have an adverse effect on retention due to loss of enamel, an important factor in bonding. PURPOSE. The object of this in vitro study was to compare the dislodgement resistance of the new types of RBFPDs, the conventional three-unit fixed partial denture, and conventional design of RBFPD (Maryland bridge). MATERIAL AND METHODS. Fifty resin mandibular left second premolars and second molars were prepared on dentiforms, according to the RBFPD design. After model fabrication (five group, n = 10), prostheses were fabricated and cemented with zinc phosphate cement. After cementation, the specimens were subjected to tensile loading at a cross head speed of 4 mm/min in a universal testing machine. The separation load was recorded and analyzed statistically using one-way analysis of variance followed by Duncan's multiple range test. RESULTS. Group V, the pin-retained RBFPDs, had the highest mean dislodgement resistance, whereas specimens of group II, the conventional RBFPDs, exhibited a significantly lower mean dislodgement resistance compared to the other 4 groups (P <.05). There were no significant differences between group I, III, and IV in terms of dislodgement resistance (P>.05). Group V had the highest mean MPa (N/$mm^2$) (P <.05). There was no significant difference between groups I, II, III and IV (P > .05). CONCLUSION. Within the limits of the design of this in vitro study, it was concluded that: 1. The modified RBFPDs which utilizes the original tooth undercuts and requires no tooth preparation, compared with the conventional design of RBFPDs, has significantly high dislodgement resistance (P < .05). 2. The modified RBFPDs which utilizes the original tooth undercuts and requires minimal tooth preparation, compared with the conventional FPDs, has significantly no difference in retention and dislodgement resistance)(P>.05). 3. The pin-retained FPDs showed a high dislodgement resistance compared to the conventional three-unit FPDs (P<.05).

Efficient Integer pel and Fractional pel Motion Estimation on H.264/AVC (H.264/AVC에서 효율적인 정화소.부화소 움직임 추정)

  • Yoon, Hyo-Sun;Kim, Hye-Suk;Jung, Mi-Gyoung;Kim, Mi-Young;Cho, Young-Joo;Kim, Gi-Hong;Lee, Guee-Sang
    • The KIPS Transactions:PartB
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    • v.16B no.2
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    • pp.123-130
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    • 2009
  • Motion estimation (ME) plays an important role in digital video compression. But it limits the performance of image quality and encoding speed and is computational demanding part of the encoder. To reduce computational time and maintain the image quality, integer pel and fractional pel ME methods are proposed in this paper. The proposed method for integer pel ME uses a hierarchical search strategy. This strategy method consists of symmetrical cross-X pattern, multi square grid pattern, diamond patterns. These search patterns places search points symmetrically and evenly that can cover the overall search area not to fall into the local minimum and to reduce the computational time. The proposed method for fractional pel uses full search pattern, center biased fractional pel search pattern and the proposed search pattern. According to block sizes, the proposed method for fractional pel decides the search pattern adaptively. Experiment results show that the speedup improvement of the proposed method over Unsymmetrical cross Multi Hexagon grid Search (UMHexagonS) and Full Search (FS) can be up to around $1.2{\sim}5.2$ times faster. Compared to image quality of FS, the proposed method shows an average PSNR drop of 0.01 dB while showing an average PSNR gain of 0.02 dB in comparison to that of UMHexagonS.

An Electronic Keyboard Instrument Using PC MIDI and USB Interface (PC MIDI와 USB Interface를 이용한 전자건반악기 개발)

  • Lim, Gi-Jeong;Lee, Jung-Chul
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.11
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    • pp.85-93
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    • 2011
  • The music education improves the creative talent, social skills and academic achievement of the students. For the efficient music education, the learner centered study is highly recommended rather than the passive education, which supports self-control in selecting teaching materials, learning patterns and speed. For the successful self learning, it is requested to develop the collaborative educational learning tools, especially electronic collaborators such as H/W and S/W. Though there exist many commercialized electronic instruments and the PC MIDI based softwares, these tools have some limits and problems for the primary student to learn playing the musical instrument by himself. In this paper, we propose a supporting tool implementation method using an electronic keyboard instrument with USB Interface and PC-based software to help the primary student to learn playing the musical instrument. We implemented an electronic keyboard instrument module compactly and at low cost using a PIC18F4550 MCU. PC based software was developed to edit musical score, process the MIDI information, and interact with the electronic keyboard instrument module. This tool can offer a similar keyboard instrument environment and can be incorporated with self learning contents.

A Study on Developing Crash Prediction Model for Urban Intersections Considering Random Effects (임의효과를 고려한 도심지 교차로 교통사고모형 개발에 관한 연구)

  • Lee, Sang Hyuk;Park, Min Ho;Woo, Yong Han
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.14 no.1
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    • pp.85-93
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    • 2015
  • Previous studies have estimated crash prediction models with the fixed effect model which assumes the fixed value of coefficients without considering characteristics of each intersections. However the fixed effect model would estimate under estimation of the standard error resulted in over estimation of t-value. In order to overcome these shortcomings, the random effect model can be used with considering heterogeneity of AADT, geometric information and unobserved factors. In this study, data collections from 89 intersections in Daejeon and estimates of crash prediction models were conducted using the random and fixed effect negative binomial regression model for comparison and analysis of two models. As a result of model estimates, AADT, speed limits, number of lanes, exclusive right turn pockets and front traffic signal were found to be significant. For comparing statistical significance of two models, the random effect model could be better statistical significance with -1537.802 of log-likelihood at convergence comparing with -1691.327 for the fixed effect model. Also likelihood ration value was computed as 0.279 for the random effect model and 0.207 for the fixed effect model. This mean that the random effect model can be improved for statistical significance of models comparing with the fixed effect model.

Design and Evaluation of a High-performance Key-value Storage for Industrial IoT Environments (산업용 IoT 환경을 위한 고성능 키-값 저장소의 설계 및 평가)

  • Han, Hyuck
    • The Journal of the Korea Contents Association
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    • v.21 no.7
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    • pp.127-133
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    • 2021
  • In industrial IoT environments, sensors generate data for their detection targets and deliver the data to IoT gateways. Therefore, managing large amounts of real-time sensor data is an essential feature for IoT gateways, and key-value storage engines are widely used to manage these sensor data. However, key-value storage engines used in IoT gateways do not take into account the characteristics of sensor data generated in industrial IoT environments, and this limits the performance of key-value storage engines. In this paper, we optimize the key-value storage engine by utilizing the features of sensor data in industrial IoT environments. The proposed optimization technique is to analyze the key, which is the input of a key-value storage engine, for further indexing. This reduces excessive write amplification and improves performance. We implement our optimization scheme in LevelDB and use the workload of the TPCx-IoT benchmark to evaluate our proposed scheme. From experimental results we show that our proposed technique achieves up to 21 times better than the existing scheme, and this shows that the proposed technique can perform high-speed data ingestion in industrial IoT environments.

Analysis of braking characteristics of electric multiple unit for train control system (열차제어시스템을 위한 전동차 제동특성 분석)

  • Choi, Don Bum;Oh, Sehchan;Kim, Min-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.887-895
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    • 2018
  • This paper presents a braking model that can be used to design the safety distance of a train control system and a train braking system to increase the volume of traffic. For the braking model, a train set (electric multiple unit composed 6 cars) was tested. The factors that can affect the braking characteristics include the friction coefficient, braking pressure, and regenerative braking. The braking pressure was classified into service and emergency braking and reflected the characteristics of the vehicle. The external force acting on the running railway car was tested in accordance with KS R 9217, and the running resistance of the train is presented in the form of a polynomial. The dynamic behavior of the train running on a straight flat line was simulated using UM 8.3. The results were validated with experimental data, and the results were reasonable. With the validated model, a stopping distance was determined according to the initial braking speed and compared with the deceleration braking model. In addition, a safety distance for the train control system could be changed according to the frictional coefficient limits. These results are expected to be useful for analyzing the dynamic behavior of trains, and for analyzing various railway environments and improving the braking performance.

Vertical Measurement and Analysis of Meteorological Factors Over Boseong Region Using Meteorological Drones (기상드론을 이용한 보성 지역 기상 인자의 연직 측정 및 분석)

  • Chong, Jihyo;Shin, Seungsook;Hwang, Sung Eun;Lee, Seungho;Lee, Seung-Hyeop;Kim, Baek-Jo;Kim, Seungbum
    • Journal of the Korean earth science society
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    • v.41 no.6
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    • pp.575-587
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    • 2020
  • Meteorological phenomena are observed by the Korea Meteorological Administration in a variety of ways (e.g., surface, upper-air, marine, ocean, and aviation). However, there are limits to the meteorological observation of the planetary boundary layer (PBL) that greatly affects human life. In particular, observations using a sonde or aircraft require significant observational costs in economic terms. Therefore, the goal of this study was to measure and analyze the meteorological factors of the vertical distribution of the see-land breeze among local meteorological phenomena using meteorological drones. To investigate the spatial distribution of the see-land breeze, a same integrated meteorological sensor was mounted on each drone at three different points (seaside, bottom of mountain, and mountainside), including the Boseong tall tower (BTT) at the Boseong Standard Weather Observatory (BSWO) in the Boseong region. Vertical profile observations for air temperature, relative humidity, wind direction, wind speed, and air pressure were conducted up to 400 m every 30 minutes from 1100 LST to 1800 LST on August 4, 2018. The spatial characteristics of meteorological phenomena for temperature, relative humidity, and atmospheric pressure were not shown at the four points. Strong winds (~8 m s-1) were observed from the midpoint (~100 m) at strong solar radiation hour, and in the afternoon the wind direction changed from the upper layer at the inland area to the west wind. It is expected that the analysis results of the lower atmospheric layer observed using the meteorological drone may help to improve the weather forecast more accurately.

NIRS Analysis of Liquid and Dry Ewe Milk

  • Nunez-Sanchez, Nieves;Varo, Garrido;Serradilla-Manrique, Juan M.;Ares-Cea, Jose L.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1251-1251
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    • 2001
  • The routine analysis of milk chemical components is of major importance both for the management of animals in dairy farms and for quality control in dairy industries. NIRS technology is an analytical technique which greatly simplifies this routine. One of the most critical aspects in NIRS analysis of milk is sample preparation and analysis modes which should be fast and straightforward. An important difficulty when obtaining NIR spectra of milk is the high water content (80 to 90%) of this product, since water absorbs most of the infrared radiation, and, therefore, limits the accuracy of calibrating for other constituents. To avoid this problem, the DESIR system was set up. Other ways of radiation-sample interaction adapted for liquids or semi-liquids exist, which are practically instantaneous and with limited or null necessity of sample preparation: Transmission and Folded Transmission or Transflectance. The objective of the present work is to compare the precision and accuracy of milk calibration equations in two analysis modes: Reflectance (dry milk) and Folded Transmission (liquid milk). A FOSS-NIR Systems 6500 I spectrophotometer (400-2500 nm) provided with a spinning module was used. Two NIR spectroscopic methods for milk analysis were compared: a) folded transmission: liquid milk samples in a 0.1 pathlength sample cell (ref. IH-0345) and b) reflectance: dried milk samples in glass fibre filters placed in a standard ring cell. A set of 101 milk samples was used to develop the calibration equations, for the two NIR analysis modes, to predict casein, protein, fat and dry matter contents, and 48 milk samples to predict Somatic Cell Count (SCC). The calibrations obtained for protein, fat and dry matter have an excellent quantitative prediction power, since they present $r^2$ values higher than 0.9. The $r^2$ values are slightly lower for casein and SCC (0.88 and 0.89 respectively), but they still are sufficiently high. The accuracy of casein, protein and SCC equations is not affected by the analysis modes, since their ETVC values are very similar in reflectance and folded transmission (0.19% vs 0.21%; 0.16% vs 0.19% and 55.57% vs 53.11% respectively), Lower SECV values were obtained for the prediction of fat and dry matter with the folded transmission equations (0.14% and 0.25% respectively) compared to the results with the reflectance ones (0.43% and 0.34% respectively). In terms of accuracy and speed of analytical response, NIRS analysis of liquid milk is recommended (folded transmission), since the drying procedure takes 24 hours. However, both analysis modes offer satisfactory results.

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Design Optimization to achieve an enhanced flatness of a Lab-on-a-Disc for liquid biopsy (액체생검용 Lab-on-a-Disc의 평탄도 향상을 위한 최적화)

  • Seokkwan Hong;Jeong-Won Lee;Taek Yong Hwang;Sung-Hun Lee;Kyung-Tae Kim;Tae Gon Kang;Chul Jin Hwang
    • Design & Manufacturing
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    • v.17 no.1
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    • pp.20-26
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    • 2023
  • Lab-on-a-disc is a circular disc shape of cartridge that can be used for blood-based liquid biopsy to diagnose an early stage of cancer. Currently, liquid biopsies are regarded as a time-consuming process, and require sophisticated skills to precisely separate cell-free DNA (cfDNA) and circulating tumor cells (CTCs) floating in the bloodstream for accurate diagnosis. However, by applying the lab-on-a-disc to liquid biopsy, the entire process can be operated automatically. To do so, the lab-on-a-disc should be designed to prevent blood leakage during the centrifugation, transport, and dilution of blood inside the lab-on-a-disc in the process of liquid biopsy. In this study, the main components of lab-on-a-disc for liquid biopsy are fabricated by injection molding for mass production, and ultrasonic welding is employed to ensure the bonding strength between the components. To guarantee accurate ultrasonic welding, the flatness of the components is optimized numerically by using the response surface methodology with four main injection molding processing parameters, including the mold & resin temperatures, the injection speed, and the packing pressure. The 27 times finite element analyses using Moldflow® reveal that the injection time and the packing pressure are the critical factors affecting the flatness of the components with an optimal set of values for all four processing parameters. To further improve the flatness of the lab-on-a-disc components for stable mass production, a quarter-disc shape of lab-on-a-disc with a radius of 75 mm is used instead of a full circular shape of the disc, and this significantly decreases the standard deviation of flatness to 30% due to the reduced overall length of the injection molded components by one-half. Moreover, it is also beneficial to use a quarter disc shape to manage the deviation of flatness under 3 sigma limits.

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