• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.1
• /
• pp.159-163
• /
• 2013

Background: This study used Surveillance, Epidemiology and End Results (SEER) pancreatic cancer data to identify predictive models and potential socio-economic disparities in pancreatic cancer outcome. Materials and Methods: For risk modeling, Kaplan Meier method was used for cause specific survival analysis. The Kolmogorov-Smirnov's test was used to compare survival curves. The Cox proportional hazard method was applied for multivariate analysis. The area under the ROC curve was computed for predictors of absolute risk of death, optimized to improve efficiency. Results: This study included 58,747 patients. The mean follow up time (S.D.) was 7.6 (10.6) months. SEER stage and grade were strongly predictive univariates. Sex, race, and three socio-economic factors (county level family income, rural-urban residence status, and county level education attainment) were independent multivariate predictors. Racial and socio-economic factors were associated with about 2% difference in absolute cause specific survival. Conclusions: This study s found significant effects of socio-economic factors on pancreas cancer outcome. These data may generate hypotheses for trials to eliminate these outcome disparities.

• The Journal of the Acoustical Society of Korea
• /
• v.23 no.2E
• /
• pp.51-55
• /
• 2004

In this paper, we propose a style-specific language model adaptation scheme using n-gram based tf*idf similarity for Korean spontaneous speech recognition. Korean spontaneous speech shows especially different style-specific characteristics such as filled pauses, word omission, and contraction, which are related to function words and depend on preceding or following words. To reflect these style-specific characteristics and overcome insufficient data for training language model, we estimate in-domain dependent n-gram model by relevance weighting of out-of-domain text data according to their n-. gram based tf*idf similarity, in which in-domain language model include disfluency model. Recognition results show that n-gram based tf*idf similarity weighting effectively reflects style difference.

• BMB Reports
• /
• v.31 no.6
• /
• pp.525-535
• /
• 1998

A critical step in the faithful translation of genetic information is specific tRNA recognition by aminoacyl-tRNA synthetases. These enzymes catalyze the covalent attachment of particular amino acids to the terminal adenosine of cognate tRNA substrates. In general, there is one synthetase for each of the twenty amino acids and each enzyme must discriminate against all of the cellular tRNAs that are specific for the nineteen noncognate amino acids. Primary sequence information combined with structural data have resulted in the division of the twenty synthetases into two classes. In recent years, several high-resolution co-crystal structures along with biochemical data have led to an increased understanding of tRNA recognition by synthetases of both classes. The anticodon sequence and the amino acid acceptor stem are the most common locations for critical recognition elements. This review will focus on acceptor stem discrimination by class II synthetases. In particular, the results of in vitro aminoacylation assays and site-directed and atomic group mutagenesis studies will be discussed. These studies have revealed that even subtle atomic determinants can provide signals for specific tRNA aminoacylation.

• International Journal of Aerospace System Engineering
• /
• v.6 no.2
• /
• pp.11-16
• /
• 2019

A system analysis program has been developed for a gas generator cycle liquid rocket engine of 30 ton class. Numerical models have been proposed for a combustor, a turbopump, a gas generator and pressure drop through a regenerative cooling system. Numerical algorithm has been validated by comparing with the published data of MC-1. The major source of error is not the numerical algorithm but the imperfect performance models of subsystems. So the precision of the program can be improved by revising the performance models using experimental data. The sea level specific impulse and vacuum specific impulse have been demonstrated for a 30 ton class gas generator engine. The optimal condition of combustor pressure and mixture ratio for specific impulse which is a typical characteristic of a gas generator cycle engine has been illustrated.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.4
• /
• pp.2567-2570
• /
• 2013

Background: This study analyzed Surveillance, Epidemiology and End Results (SEER) data to assess if socio-economic factors (SEFs) impact on endometrial cancer survival. Materials and Methods: Endometrial cancer patients treated from 2004-2007 were included in this study. SEER cause specific survival (CSS) data were used as end points. The areas under the receiver operating characteristic (ROC) curve were computed for predictors. Time to event data were analyzed with Kaplan-Meier method. Univariate and multivariate analyses were used to identify independent risk factors. Results: This study included 64,710 patients. The mean follow up time (S.D.) was 28.2 (20.8) months. SEER staging (ROC area of 0.81) was the best pretreatment predictor of CSS. Histology, grade, race/ethnicity and county level family income were also significant pretreatment predictors. African American race and low income neighborhoods decreased the CSS by 20% and 3% respectively at 5 years. Conclusions: This study has found significant endometrial survival disparities due to SEFs. Future studies should focus on eliminating socio-economic barriers to good outcomes.

• Journal of Microbiology and Biotechnology
• /
• v.18 no.6
• /
• pp.1130-1135
• /
• 2008

The effect of pH on anaerobic hydrogen production was investigated under various pH conditions ranging from pH 3 to 10. When the modified Gompertz equation was applied to the statistical analysis of the experimental data, the hydrogen production potential and specific hydrogen production rate at pH 5 were 1,182 ml and 112.5 ml/g biomass-h, respectively. In this experiment, the maximum theoretical hydrogen conversion ratio was 22.56%. The Haldane equation model was used to find the optimum pH for hydrogen production and the maximum specific hydrogen production rate. The optimum pH predicted by this model is 5.5 and the maximum specific hydrogen production rate is 119.6 ml/g VSS-h. These data fit well with the experimented data($r^2=0.98$).

• Journal of Environmental Science International
• /
• v.9 no.1
• /
• pp.75-80
• /
• 2000

Kinetic data for the acid phase anaerobic digestion were presented in this study and the constants were determined with acid production rate and gas production rate. Process models based on continuous culture theory were used to describe the characteristics of the acid forming microorganisms and to enable further development toward utilization of the process in a more rational manner. Acid phase digestion can be separated with appropriate manipulation of hydraulic retention time in anaerobic digestion. Kinetic analysis of data from the various hydraulic retention times using a phase specific model obtained form the acid phase indicated maximum specific growth rate of 0.40/h, saturation constant of 2,000mgCOD.$\ell$, yield coefficient of 0.35 mgVSS/msCOD utilized and decay constant of 0.04/h for the acid production rate. Similar analysis of data for the gas production rate indicated maximum specific growth rate of 0.003/h, saturation constant of 2,200mgCOD/$\ell$, yield coefficient of 0.035 mgVSS/mgCOD utilized and decay constant of 0.06/h.

• Journal of IKEEE
• /
• v.19 no.4
• /
• pp.625-631
• /
• 2015

In this paper, an 8051 microcontroller with application-specific instructions and I/O ports for data transmission is designed. The designed microcontoller includes two UART ports and one SMBus port to control external devices and to transmit data with them. Application-specific instruction is developed and added to the instruction set to exploit these I/O ports. So the designed microcontroller can perform multi-device control and multi-byte transmission. Also, it can reduce the code size of the application program. Especially, the designed microcontroller does not stall and can execute other programs during data transmission, which significantly increases its efficiency. Synthesized in 0.18 um technology, the area overhead due to application-specific instructions was negligible. Operations of all instructions and I/O ports were verified to run correctly on a FPGA board.

• The Korean Journal of Health Service Management
• /
• v.10 no.3
• /
• pp.199-211
• /
• 2016

Objectives : This study compared the influencing factors on life satisfaction after retirement between public pension and specific corporate pension recipients. Methods : This study used the fifth year data of 2013 from the raw data of the Korean Retirement and Income Study collected by the National Pension Research Institute. The data analysis in this study was done with the chi-square test, t-test, and linear regression using SPSS ver. 22.0 to verify the relevance between the general characteristics of pension recipients. Results : This study shows that there was a difference in expenditures and health care costs between public pension and special corporate pension recipients. The influencing factors on life satisfaction for public pension recipients were the level of spending, whether there were limitations in daily life and social activity, whether recipients had financial assets and health care costs while for specific corporate pension recipients, they were education level, level of spending and chronic diseases. Conclusions : A health policy that maximizes life satisfaction and takes into account the type of pencion needs to be considered and implemented.

• Journal of the Korean Society of Physical Medicine
• /
• v.13 no.3
• /
• pp.113-120
• /
• 2018

PURPOSE: This study was conducted to investigate the characteristics of a specific functional shoe in terms of the range of motion (ROM) of ankle and foot joints during walking when compared to a standardized shoe. METHODS: Kinematic ROM data pertaining to ankle, tarsometatarsal, and metatarsophalangeal joints were collected from twenty-six healthy individuals during walking using a ten-camera motion analysis system. Kinematic ROM of each joint in three planes was obtained over ten walking trials consisting of two different shoe conditions. Visual3D motion analysis was finally used to coordinate the kinematic data. All kinematic ROM data were interpolated using a cubic spline algorithm and low-pass filtered with a cutoff frequency of 6 Hz for smoothing. RESULTS: The overall ROM of the ankle joint in the sagittal and coronal planes when wearing the specific functional shoe was significantly decreased in both ankles during walking when compared to wearing a standard shoe (p<.05). Significantly more flexibility was observed when wearing the specific functional shoe in the tarsometatarsal and metatarsophalangeal joints compared to a standard shoe (p<.05). CONCLUSION: Although clinical application of the specific functional shoe has shown clear positive effects on knee and ankle moments, the results of this study provide important background information regarding the kinematic mechanisms of these effects.