• Investigative Magnetic Resonance Imaging
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• v.25 no.2
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• pp.118-128
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• 2021

Purpose: To investigate the value of MR textural analysis, including use of diffusion-weighted imaging (DWI) to differentiate malignant from benign soft-tissue tumors on 3T MRI. Materials and Methods: We enrolled 69 patients (25 men, 44 women, ages 18 to 84 years) with pathologically confirmed soft-tissue tumors (29 benign, 40 malignant) who underwent pre-treatment 3T-MRI. We calculated MR texture, including mean, standard deviation (SD), skewness, kurtosis, mean of positive pixels (MPP), and entropy, according to different spatial-scale factors (SSF, 0, 2, 4, 6) on axial T1- and T2-weighted images (T1WI, T2WI), contrast-enhanced T1WI (CE-T1WI), high b-value DWI (800 sec/mm²), and apparent diffusion coefficient (ADC) map. We used the Mann-Whitney U test, logistic regression, and area under the receiver operating characteristic curve (AUC) for statistical analysis. Results: Malignant soft-tissue tumors had significantly lower mean values of DWI, ADC, T2WI and CE-T1WI, MPP of ADC, and CE-T1WI, but significantly higher kurtosis of DWI, T1WI, and CE-T1WI, and entropy of DWI, ADC, and T2WI than did benign tumors (P < 0.050). In multivariate logistic regression, the mean ADC value (SSF, 6) and kurtosis of CE-T1WI (SSF, 4) were independently associated with malignancy (P ≤ 0.009). A multivariate model of MR features worked well for diagnosis of malignant soft-tissue tumors (AUC, 0.909). Conclusion: Accurate diagnosis could be obtained using MR textural analysis with DWI and CE-T1WI in differentiating benign from malignant soft-tissue tumors.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1142-1151
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• 2021

Objective: To evaluate microstructural damage in high myopia (HM) patients using 3T diffusion kurtosis imaging (DKI). Materials and Methods: This prospective study included 30 HM patients and 33 age- and sex-matched healthy controls (HCs) with DKI. Kurtosis parameters including kurtosis fractional anisotropy (FA), mean kurtosis (MK), axial kurtosis (AK), and radial kurtosis (RK) as well as diffusion metrics including FA, mean diffusivity, axial diffusivity (AD), and radial diffusivity derived from DKI were obtained. Group differences in these metrics were compared using tract-based spatial statistics. Partial correlation analysis was used to evaluate correlations between microstructural changes and disease duration. Results: Compared to HCs, HM patients showed significantly reduced AK, RK, MK, and FA and significantly increased AD, predominately in the bilateral corticospinal tract, right inferior longitudinal fasciculus, superior longitudinal fasciculus, inferior fronto-occipital fasciculus, and left thalamus (all p < 0.05, threshold-free cluster enhancement corrected). In addition, DKI-derived kurtosis parameters (AK, RK, and MK) had negative correlations (r = -0.448 to -0.376, all p < 0.05) and diffusion parameter (AD) had positive correlations (r = 0.372 to 0.409, all p < 0.05) with disease duration. Conclusion: HM patients showed microstructural alterations in the brain regions responsible for motor conduction and vision-related functions. DKI is useful for detecting white matter abnormalities in HM patients, which might be helpful for exploring and monitoring the pathogenesis of the disease.

• Investigative Magnetic Resonance Imaging
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• v.26 no.2
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• pp.104-116
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• 2022

The purpose of this study is to systematically determine an optimal percentile cut-off in histogram analysis for calculating the mean parameters obtained from a non-Gaussian continuous-time random-walk (CTRW) diffusion model for differentiating individual glioma grades. This retrospective study included 90 patients with histopathologically proven gliomas (42 grade II, 19 grade III, and 29 grade IV). We performed diffusion-weighted imaging using 17 b-values (0-4000 s/mm²) at 3T, and analyzed the images with the CTRW model to produce an anomalous diffusion coefficient (D_m) along with temporal (𝛼) and spatial (𝛽) diffusion heterogeneity parameters. Given the tumor ROIs, we created a histogram of each parameter; computed the P-values (using a Student's t-test) for the statistical differences in the mean D_m, 𝛼, or 𝛽 for differentiating grade II vs. grade III gliomas and grade III vs. grade IV gliomas at different percentiles (1% to 100%); and selected the highest percentile with P < 0.05 as the optimal percentile. We used the mean parameter values calculated from the optimal percentile cut-offs to do a receiver operating characteristic (ROC) analysis based on individual parameters or their combinations. We compared the results with those obtained by averaging data over the entire region of interest (i.e., 100th percentile). We found the optimal percentiles for D_m, 𝛼, and 𝛽 to be 68%, 75%, and 100% for differentiating grade II vs. III and 58%, 19%, and 100% for differentiating grade III vs. IV gliomas, respectively. The optimal percentile cut-offs outperformed the entire-ROI-based analysis in sensitivity (0.761 vs. 0.690), specificity (0.578 vs. 0.526), accuracy (0.704 vs. 0.639), and AUC (0.671 vs. 0.599) for grade II vs. III differentiations and in sensitivity (0.789 vs. 0.578) and AUC (0.637 vs. 0.620) for grade III vs. IV differentiations, respectively. Percentile-based histogram analysis, coupled with the multi-parametric approach enabled by the CTRW diffusion model using high b-values, can improve glioma grading.

• Journal of the Economic Geographical Society of Korea
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• v.6 no.1
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• pp.171-191
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• 2003

Today universities are regarded as one of the key institutions in the national and regional innovation systems. First of all the diffusion and distribution of the knowledges, technologies, information and know-hows from higher educations to regions are capable of promoting an innovation-led regional development. This study aims to evaluate the transfer and spatial diffusion of knowledge and technology from the Chonnam National University(CNU) in Kwangju to the regions and to focus the analysis of the technology transfer, personnel transfer and spin-off development. The results show that there are some differences in the spatial range and effects of the knowledge and technology transfer of the CNU by the type of transfers. And the Analysis provide evidence that the knowledge and technology distributions from the CNU make more and less positive contribution to regional developments.

• Journal of the Korean association of regional geographers
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• v.1 no.1
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• pp.103-116
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• 1995

The purpose of this paper is to explore a brief review of trends in existing geographical research on music and to analyze music by the 5 themes of geography and to explore a variety of classroom techniques which examine song lyrics for their geographic content. The results of this paper are summarized as followed : Firstly, the trends in geographical research on music can be classified into five areas, the first is on spatial diffusion in music, the second on spatial diffusion in music, the third on regional division in music, the fourth on regional characteristics in music, the fifth on pedagogical tools in the teaching of geography. Secondly, music holds numerous possibilities for regional geographical study. The lyrics of music are littered with geographical term through which song writers impart image of culture, the distinct geographical nature of music lyrics gives rise to many geographical question, also, music lyrics gives place its special character. The results of analyses by the 5 themes of geography indicate that music are useful to learning of regional geography. The application of music to learning regional geography attracts much attentions. In the respect of importance of learning new regional geography, and in the respect of adapting globalization have to be focused on this subject.

• Journal of the Korean Society of Radiology
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• v.12 no.2
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• pp.253-260
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• 2018

Diffusion tensor images were obtained to investigate the damage of brain white matter in non-smokers and an adequate drinking group (less than 10 points) selected by scores of the Korean versions of alcohol use disorders identification test questionnaire. Factional anisotropy (FA) values, according to the variables of age and body mass index (BMI), were not statistically significant in all regions of the brain white matter after measurement of factional anisotropy (FA) values by the tract-based spatial statics (TBSS) method. In other words, age and body mass index (BMI) do not significantly affect the microstructural changes of the brain white matter.

• Journal of Korea Spatial Information System Society
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• v.12 no.1
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• pp.10-17
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• 2010

Sensor nodes used in Geosensor network are resource limited and power constrained. So it is necessary to research on routing protocols to gather data by using energy efficiently. Wireless sensor networks collect data gathered from sensor nodes by transfering it to the sink using multihop. However, it has two problems. First, the existing works require unnecessary data transmission for choosing a proper parent node to transfer data. Secondly, they have a large number of data transmission because each sensor node has a different path. To solves the problems, we, in this paper, propose a designated path based data aggregation scheme for efficient energy management in WSNs. The proposed scheme can reduce unnecessary data transmission by pre-determining a set of paths and can enable all the sensor nodes to participate in gathering data by running them in round-robin fashion. We show from performance analysis that the proposed scheme is more energy efficient than the existing directed diffusion(DD) and the hierarchical data aggregation(HDA).

• Journal of the Korean Association of Geographic Information Studies
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• v.5 no.3
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• pp.107-117
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• 2002

Public policy responses to the digital/information revolution and the micro-economic reforms that it facilitates have inspired exploration of the scope for local government implementation of digital spatial data handling(DSDH) of information relating to, among other things, asset inventory, environmental and utility management, address management, and planning. The results from these explorations are such that few doubt the value of bringing the public policies to practice, but diffusion rate and pattern of the approaches demonstrated by the scoping experiments will reflect institutional/cultural matters, indicators of the relative significance of which might be at least partly predicted from appraisal of case studies. This argument is exemplified by reference to case studies in adoption of DSDH by local government organizations in Korea and in Australia.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.10C
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• pp.1023-1032
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• 2003

Object-based coding, such as MPEG-4, enables various content-based functionalities for multimedia applications. In order to support such functionalities, as well as to improve coding efficiency, each frame of video sequences should be segmented into video objects. In this paper. we propose an effective video object segmentation method using nonlinear multiscale filtering and spatio-temporal information. Proposed method performs a spatial segmentation using a nonlinear multiscale filtering based on the stabilized inverse diffusion equation(SIDE). And, the segmented regions are merged using region adjacency graph(RAG). In this paper, we use a statistical significance test and a time-variant memory as temporal segmentation methods. By combining of extracted spatial and temporal segmentations, we can segment the video objects effectively. Proposed method is more robust to noise than the existing watershed algorithm. Experimental result shows that the proposed method improves a boundary accuracy ratio by 43% on "Akiyo" and by 29% on "Claire" than A. Neri's Method does.

• Journal of the Korean Association of Geographic Information Studies
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• v.26 no.4
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• pp.188-199
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• 2023

CCTV is widely used as a crime prevention method globally; however, there is insufficient evidence regarding its effectiveness. This study assesses the suitability of CCTV locations and their impact on crime prevention. First, to analyze the appropriateness of the location of CCTVs, we overlaid the locations of crimes and CCTV, and found that there are many cases where CCTV were placed where crime rarely occurred. Using various cases, we verified CCTV's crime prevention effectiveness. The WDQ was applied to comprehensively analyze the impact of CCTV surveillance area and surrounding areas to determine the crime prevention effect. As a result of the analysis, CCTV was found to be effective in preventing crime. In 53.09% of the cases, there was a diffusion effect of crime control benefits in the surrounding area, which was four times more than the cases with a transfer effect. Thus, strategically installing CCTV in appropriate locations enhances crime prevention effectiveness based on spatial analysis.