• International Journal of Vascular Biomedical Engineering
• /
• v.3 no.1
• /
• pp.1-5
• /
• 2005

Background: Coronary atherosclerosis artery disease is the leading cause of morbidity and mortality. Coronary artery bypass grafting (CABG) which utilizes the saphenous vein graft, has helped in alleviating the suffering of these patients. Newer techniques are being developed to improve upon the techniques. Still there is significant number of failures, leading to re-grafting or re-vascularization. Some studies have helped in identifying the high and low shear stress regions. Further studies based on their realistic models are required. Material, methods and results: we developed the realistic model of fully blocked right coronary with bypass graft placed at angle of $5^0$ with curvature similar to that of artery. Pulsatile flow of birefringent solution through this model by polarized light was visualized. The images of complete flow field in the model were recorded and analyzed. Regions of high flow disturbances which are prone to further changes are identified. Existence of recirculation in the blocked coronary may initiate new blood-tissue interactions deleterious to bypass graft. Conclusion: Our study shows that by selecting the procedure to place bypass graft at minimum angle with curvature similar to that of artery and smooth sutures may improve the life span of the graft. This study also identified that coronary blocked regions contributing by recirculation flow at the proximal and distal regions of bypass which may require further studies.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.6 no.5
• /
• pp.29-36
• /
• 2002

In the maintenance and retrofit planning of a bridge system, the optimal strategy for inspection and repair are suggested by minimizing the expected total life-cycle cost, which includes the initial cost, the costs of inspection, repair, and failure. Degradation of seismic performance is modeled by using a damage function. And failure probability is computed according to the degree of damage detection by random vibration theory and the event tree analysis. As an example to illustrate the proposed approach, a 10-span continuous bridge structure is used. The numerical results show that the optimum number of the inspection and the repair are increased, as the seismic intensity is increased and the soil condition of a site becomes more flexible.

• Smart Structures and Systems
• /
• v.17 no.5
• /
• pp.691-708
• /
• 2016

Recently, number of smart material are investigated and widely used in civil construction and other industries. Present study investigates the application of smart semi-active piezoelectric friction damper (PFD) made with piezoelectric material for the seismic control of the horizontally curved bridge isolated with lead rubber bearing (LRB). The main aim of the study is to investigate the effectiveness of hybrid system and to find out the optimum parameters of PFD for seismic control of the curved bridge. The selected curved bridge is a continuous three-span concrete box girder supported on pier and rigid abutment. The PFD is located between the deck and abutments or piers in chord and radial directions. The bridge is excited with four different earthquake ground motions with all three components (i.e. two horizontal and a vertical) having different characteristics. It is observed that the use of semi-active PFD with LRB is quite effective in controlling the response of the curved bridge as compared with passive system. The incorporation of the smart damper requiring small amount of energy in addition with an isolation system can be used for effective control the curved bridge against the dynamic loading.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.19 no.1
• /
• pp.100-106
• /
• 2006

Today, restricted energy sources, environmental considerations and the high cost of transporting fuel have limited the number and location of available power plant sites. The pressures resulting from these conditions have tended to require the construction of long, high-capacity, high-voltage power lines. it's used to adapt to STACIR/AW(Super Thermal-resistant Aluminum alloy Conductors, aluminum-clad Invar-Reinforced) conductor for coping with these situations. STACIR/AW conductor was formed by the combination of INVAR/AW as the core for low sag and super thermal-resistant aluminum alloy conductor for current capacity increase. increase of temperature by current capacity and long span lines make the susceptible to the deterioration of thermo-mechanical properties(conductivity, tensile strength, E-modulus and twist property et al). In the present work, changes of thermo-mechanical properties with aging have been studied in STACIR/AW $410 mm^2$ conductor with forms of single wire and strand wire.

• The Journal of Korean Medicine
• /
• v.22 no.2
• /
• pp.22-30
• /
• 2001

This study was attempted to investigate the anti-tumor and anti-metastatic effects of Sobokchukeotang(SBCT) and Kamisobokchukeotang(KSBCT). Cytotoxicity against various cancer cell lines, anti-adhesion, pulmonary colonization, anti-angiogenesis, and T/C% were evaluated. SBCT and KSBCT exhibited no cytotoxicity against HT-1080, A549, SK-OV-3, B16-F10 and SK-Mel-2 cell lines. In inhibitory effect on DNA topoisomerase I, the $IC_{50S}$ were shown $250-500{\;}\mu\textrm{g}/ml$ of SBCT and $62.5-125{\;}\mu\textrm{g}/ml$ of KSBCT respectively. In the in vivo experiments, SBCT(135.98%) and KSBCT(151.92%) apparently increased the life span of mice bearing sarcoma-180. KSBCT significantly inhibited the adhesion of HT-1080 to complex extracellular matrix in a dose-dependent manner in contrast to SBCT. In pulmonary colonization assay by B16-F10, a number of colonies in the lungs were decreased more significantly in KSBCT group than those in SBCT group. In vitro neovascularization and CAM assay, angiogenesis was more significantly inhibited in KSBCT-treated group than in SBCT- treated group. Above results suggests that KSBCT is more effectively applied to prevention and treatment of cancer than SBCT.

• Proceedings of the KSME Conference
• /
• 2001.11b
• /
• pp.746-751
• /
• 2001

We used a cylindrical model which simulates turbine blade leading edge to investigate the effects of free-stream turbulence intensity and blowing ratio on film cooling of turbine blade leading edge. Tests are carried out in a low-speed wind tunnel on a cylindrical model with three rows of injection holes. Mainstream Reynolds number based on the cylinder diameter was $7.1\times10^4$. Two types of turbulence grid are used to increase a free-stream turbulence intensity. The effect of coolant blowing ratio was studied for various blowing ratios. For each blowing ratios, wall temperatures around the surface of the test model are measured by thermocouples installed inside the model. Results show that blowing ratios have small effect on spanwise-averaged film effectiveness at high free-stream turbulence intensity. However, an increase in free-stream turbulence intensity enhances significantly spanwise-averaged film effectiveness at low blowing ratio.

• Structural Engineering and Mechanics
• /
• v.9 no.3
• /
• pp.289-304
• /
• 2000

This study discusses on the experimental and analytical results of the global buckling tests, carried out on aluminum alloy double layer space grids composed of tubular members, ball joints and connecting bolts at the member ends, with the purpose of demonstrating the effectiveness of a simplified analysis method using an equivalent slenderness ratio for the members. Because very few experiments have been carried out on this type of aluminum space grids, the buckling behavior is investigated experimentally over the post buckling regions using several space grid specimen with various values for the member slenderness ratio. The observed behavior duping the experiments is compared with the analytically obtained results. The comparison is made based on two different schemes; one on the plastic hinge method considering a bending moment-axial force interaction for members and the other on a method using an equivalent slenderness ratio. It is confirmed that the equivalent slenderness method can be effectively applied, even in the post buckling regions, once the effects of the rotational rigidity at the ball joints are appropriately evaluated, because the rigidity controls the buckling behavior. The effectiveness of the equivalent slenderness method will be widely utilized for estimation of the ultimate strength, even in post buckling regions for large span aluminum space grids composed of an extreme large number of nodes and members.

• Wind and Structures
• /
• v.18 no.3
• /
• pp.235-252
• /
• 2014

An effective numerical technique to calculate the reactions of a multi-spanned transmission line conductor system, under arbitrary loads varying along the spans, is developed. Such variable loads are generated by High Intensity Wind (HIW) events in the form of tornadoes and downburst. First, a semi-closed form solution is derived to obtain the displacements and the reactions at the ends of each conductor span. The solution accounts for the nonlinearity of the system and the flexibility of the insulators. Second, a numerical scheme to solve the derived closed-form solution is proposed. Two conductor systems are analyzed under loads resulting from HIW events for validation of the proposed technique. Non-linear Finite Element Analyses (FEA) are also conducted for the same two systems. The responses resulting from the technique are shown to be in a very good agreement with those resulting from the FEA, which confirms the technique accuracy. Meanwhile, the semi-closed form technique shows superior efficiency in terms of the required computational time. The saving in computational time has a great advantage in predicting the response of the conductors under HIW events, since this requires a large number of analyses to cover different potential locations and sizes of those localized events.

• Structural Engineering and Mechanics
• /
• v.50 no.2
• /
• pp.137-149
• /
• 2014

In this study, modal parameters such as natural frequencies, mode shapes and damping ratios of RC frames with low strength are determined for different construction stages using ambient vibration test. For this purpose full scaled, one bay and one story RC frames are produced and tested for plane, brick in-filled and brick in-filled with plaster conditions. Measurement time, frequency span and effective mode number are determined by considering similar studies and literature. To obtain experimental dynamic characteristics, Enhanced Frequency Domain Decomposition and Stochastic Subspace Identification techniques are used together. It is shown that the ambient vibration measurements are enough to identify the most significant modes of RC frames. The results indicate that modal parameters change significantly depending on the construction stages. In addition, Infill walls increase stiffness and change the mode shapes of the RC frame. There is a good agreement between mode shapes obtained from brick in-filled and in-filled with plaster conditions. However, some differences are seen in plane frame, like expected. Dynamic characteristics should be verified using finite element analysis. Finally, inconsistency between experimental and analytical dynamic characteristics should be minimize by finite element model updating using some uncertain parameters such as material properties, boundary condition and section properties to reflect the current behavior of the RC frames.

• Computers and Concrete
• /
• v.21 no.1
• /
• pp.11-20
• /
• 2018

The possibilities of non-linear analysis of reinforced-concrete structures are under development. In particular, current research areas include structural analysis with the application of advanced computational and material models. The submitted article aims to evaluate the possibilities of the determination of material properties, involving the tensile strength of concrete, fracture energy and the modulus of elasticity. To evaluate the recommendations for concrete, volume computational models are employed on a comprehensive series of tests. The article particularly deals with the issue of the specific properties of fracture-plastic material models. This information is often unavailable. The determination of material properties is based on the recommendations of Model Code 1990, Model Code 2010 and specialized literature. For numerical modelling, the experiments with the so called "classic" concrete beams executed by Bresler and Scordelis were selected. It is also based on the series of experiments executed by Vecchio. The experiments involve a large number of reinforcement, cross-section and span variants, which subsequently enabled a wider verification and discussion of the usability of the non-linear analysis and constitutive concrete model selected.